Macfresh 0.25mg Tablet 10'S

Introduction About MACFRESH 0.25MG TABLET

MACFRESH 0.25MG TABLET contains Etizolam which belongs to the group of medicines called Antidepressants. It is used in the management of short-term anxiety. Anxiety is a mental health disease characterized by fear, worry, and excessive nervousness.

MACFRESH 0.25MG TABLET is also used to manage insomnia. Insomnia is a sleep disease that causes trouble in falling asleep or staying asleep.

MACFRESH 0.25MG TABLET can have a serious side effect like suicidal thoughts, consult your doctor immediately if you have suicidal or aggressive thoughts.

MACFRESH 0.25MG TABLET is not recommended for use in patients having severe liver disease, lung diseases, myasthenia gravis, acute narrow-angle glaucoma (increased pressure in the eye), chronic psychosis, or porphyria.

Before taking MACFRESH 0.25MG TABLET, inform your doctor if you have kidney disease, alcohol addiction, or personality disorders. MACFRESH 0.25MG TABLET is not recommended for use in pregnant or breastfeeding women. MACFRESH 0.25MG TABLET can be used in children and adolescents. However, consult with your child’s doctor before giving it to your child.

In elderly patients, MACFRESH 0.25MG TABLET should be used with caution. The most common side effects of taking MACFRESH 0.25MG TABLET are decreased heart rate, impaired coordination, sleepiness, yawning, decreased appetite, nausea, vomiting, dry mouth and headache. Ask for your doctor’s advice if any of these worsen or doesn’t improve.

Uses Of MACFRESH 0.25MG TABLET

Manage:

• short-term anxiety
• insomnia

How MACFRESH 0.25MG TABLET Works

MACFRESH 0.25MG TABLET work by increasing the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) and inducing sleep. Thereby, relaxes muscles, reduces anxiety, and helps to fall asleep.

How to use MACFRESH 0.25MG TABLET

Take MACFRESH 0.25MG TABLET as advised by your physician. Take this medicine with or without meals.

For Tablet, Capsule: Swallow MACFRESH 0.25MG TABLET with a glass of water. Do not crush or chew the medicine.

For Mouth Dissolving Tablet, Orally Disintegrating Tablet: Place MACFRESH 0.25MG TABLET inside your mouth and allow it to dissolve completely. Do not swallow or chew the medicine.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Continue to take MACFRESH 0.25MG TABLET for the stipulated duration prescribed by your doctor to achieve better results.

Side Effects Of MACFRESH 0.25MG TABLET

How To Manage Side Effects

Nausea:

Take this medicine with or after meals. Stick to simple meals while taking this medicine. Avoid eating rich or spicy food. Do not take any medication on your own. Ask for your doctor’s advice if nausea doesn’t improve.

Headache:

Try to take rest and don’t involve yourself in exertive activities. Rest in a quiet and dark room. Apply a pain-relieving balm on your forehead. Ask for your doctor’s advice if headache doesn’t improve

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, oily, or sweet foods. Avoid carbonated drinks. Ask for your doctor’s advice if vomiting doesn’t improve.

Dry mouth:

Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your physician for advice.

Warning & Precautions

Pregnancy

MACFRESH 0.25MG TABLET is not recommended to use among pregnant women. Consult your doctor before taking it.

Breastfeeding

MACFRESH 0.25MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking it.

Driving and Using Machines

Do not drive or use machines if you feel sleepy or dizzy after taking MACFRESH 0.25MG TABLET.

Alcohol

Avoid drinking alcohol while taking MACFRESH 0.25MG TABLET as it can worsen the side effects.

Kidney

MACFRESH 0.25MG TABLET should be used with caution in patients having kidney diseases such as impaired kidney function. Consult your doctor before taking it.

Liver

MACFRESH 0.25MG TABLET is not recommended for use in patients with liver disease such as severe hepatic impairment and should be used with caution in patients having impaired liver function. Consult your doctor before taking MACFRESH 0.25MG TABLET.

Allergy

Do not take MACFRESH 0.25MG TABLET if you are allergic to Etizolam or any of the other ingredients of this medicine.

Lungs

MACFRESH 0.25MG TABLET is not recommended for use in patients having lung diseases such as respiratory depression or acute pulmonary insufficiency. It should be used with caution in patients having chronic pulmonary insufficiency. Consult your doctor before taking MACFRESH 0.25MG TABLET.

Interactions

A. Drug-Drug interactions:

Before taking MACFRESH 0.25MG TABLET, inform your doctor if you are taking any of the following medicine:

• medicines used to manage depression (Ex. fluoxetine, paroxetine), psychosis (Ex. risperidone, olanzapine), schizophrenia (Ex. clozapine)
• medicines used to manage allergy (Ex. levocetirizine)
• medicines used as general anesthetics (Ex. propofol, isoflurane)
• medicines used to manage sleep problems (Ex. zolpidem)
• medicines used to manage severe pain (Ex. tramadol, methadone)
• medicines used to manage stomach problems (Ex. cisapride, cimetidine, esomeprazole, omeprazole)
• medicines used to manage heart diseases (Ex. amlodipine, diltiazem, clonidine, moxonidine, propranolol, bisoprolol, nitroglycerine, isosorbide, hydralazine, minoxidil, losartan. nitroprusside)
• medicines used to manage low blood sugar (Ex. diazoxide)
• medicines used to manage chronic alcoholism (Ex. disulfiram)
• medicines used to manage fluid build-up in the body (Ex. spironolactone, furosemide)
• medicines used as muscle relaxants Ex. thiocolchicine)
• medicines used to manage Parkinson’s disease (Ex. levodopa)
• medicine used to manage withdrawal symptoms of opioid withdrawal (Ex. lofexidine)
• medicines used to manage fungal infections (Ex. ketoconazole, fluconazole)
• medicines used to manage epilepsy (Ex. clonazepam, phenytoin)
• medicines used to manage certain infections (Ex. erythromycin)

Overdosage:

If you or anyone else accidentally take too much of MACFRESH 0.25MG TABLET, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep MACFRESH 0.25MG TABLET out of reach of children
• Store MACFRESH 0.25MG TABLET below 30°C

FAQs About MACFRESH 0.25MG TABLET

What is MACFRESH 0.25MG TABLETused for?

MACFRESH 0.25MG TABLET contains Etizolam which belongs to the group of medicines called Antidepressants. It is used in the management of short-term anxiety and insomnia.

Can MACFRESH 0.25MG TABLETbe used in children?

MACFRESH 0.25MG TABLET can be used in children and adolescents. However, consult with your child’s doctor before giving MACFRESH 0.25MG TABLET to your child.

Can I stop taking MACFRESH 0.25MG TABLET?

Take MACFRESH 0.25MG TABLET for the time it has been prescribed to you. Do not stop taking MACFRESH 0.25MG TABLET until and unless your doctor advice you to. Stopping early or taking for prolonged periods of time may cause some unwanted side effects. Ask for your doctor’s advice if you wish to discontinue taking MACFRESH 0.25MG TABLET.

Can I drink alcohol while taking MACFRESH 0.25MG TABLET?

Avoid consumption of alcohol while taking MACFRESH 0.25MG TABLET as it can worsen your side effects or can make you feel dizzier. Consult your doctor before taking it.

Does MACFRESH 0.25MG TABLET affects my ability to drive?

Do not drive or use machines if you feel sleepy and dizzy after taking MACFRESH 0.25MG TABLET or until you know how it affects you. You can resume doing your activities once you feel normal again.

Is it safe to use MACFRESH 0.25MG TABLET in pregnant and breastfeeding women?

MACFRESH 0.25MG TABLET is not recommended to use among pregnant and breastfeeding women. Consult your doctor before taking it.

References

1. Sean C Sweetman. Anxiolytic Sedatives Hypnotics and Antipsychotics. Martindale-The Complete Drug Reference. Thirty Sixth Edition. 2009. Page – 996.

2. Yuki Omori, Takashi Kanbayashi, Yohei Sagawa, Aya Imanishi, Ko Tsutsui, Yuya Takahashi, Masahiro Takeshima, Manabu Takaki, Seiji Nishino, Tetsuo Shimizu. Low dose of aripiprazole advanced sleep rhythm and reduced nocturnal sleep time in the patients with delayed sleep phase syndrome: an open-labeled clinical observation. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. May 2018. [Accessed on 9th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965391/

3. Lohit Somashekar Reddy, Raghavendra Nayak, Sameeran S Chate, Nanasaheb M Patil. Etizolam: Use and safety profile in children and adolescent. Research Gate. December 2016 https://www.researchgate.net/publication/328529331_Etizolam_Use_and_safety_profile_in_children_and_adolescent#:~:text=Conclusions%3A%20Etizolam%20is%20effective%20in,tolerated%20with%20minimal%20adverse%20effects.

4. Scottish Drugs Forum. Etizolam [Revised in June 2014] [Accessed on 9th September 2022] https://www.nhsaaa.net/media/4654/etizolam_infosheet_sdf_drugwatch1_1-2.pdf

5. Vibcare Pharma Pvt. Ltd. Etizovib (Etizolam). [Accessed on 9th September 2022] https://vibcare.co.in/etizolam/

6. MIMS. Etizolam. [Accessed on 9th September 2022] https://www.mims.com/philippines/drug/info/etizolam?mtype=generic

7. Neuracle Lifesciences Private Limited. Ripstress (Etizolam). [Accessed on 9th September 2022] https://www.neuraclelife.com/product/etizolam-0-5-mg/

8. Leeford Healthcare. Nitocal 0.25 (Etizolam). [Accessed on 9th September 2022] https://www.leeford.in/product/757/nitocalm-025

9. Leeford Healthcare. Nitocal 0.5 (Etizolam). [Accessed on 9th September 2022] https://www.leeford.in/product/758/nitocalm-05

10. JABS Biotech Pvt Ltd. Etijab-1 (Etizolam). [Accessed on 9th September 2022] https://www.jabsbiotech.com/product/etijab-1

11. Drug Bank. Etizolam. [Accessed on 9th September 2022] https://go.drugbank.com/drugs/DB09166

Author Details

Written By Dr. Priyanka Goel - BDS

Reviewed For Accuracy By Dr. Aravindan Balachandran - MBBS, MD (Psychiatry)

Last updated on 01 Nov 2022 | 02:21 PM(IST)