New Revised MRP, 100% GST benefit passed LUMETHER 80 ORANGE FLAVOUR Dispersible Tablet 6's
Netmeds First Membership
Quick Links
Introduction About LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET is a combination of Artemether and Lumefantrine which belongs to the group of medicines called Antimalarials. It is used in infants, children and adults for the management of acute uncomplicated malaria (mosquito borne disease with symptoms of fever with chills, tiredness, nausea, vomiting, stomach pain) caused by a parasite called plasmodium falciparum.
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET should be used with caution in patients with severe liver or kidney problems or if the patient feels worse or unwell to eat and drink.
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET is not recommended for use in patients having severe type of malarial infection affecting the lungs, kidney or brain, heart condition such as changes in the heart rhythm, slow heartbeat or severe heart disease and low levels of electrolytes such as potassium or magnesium in the blood.
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET is generally not recommended for use during the first trimester of pregnancy and it should be used with caution during the second and third trimester of pregnancy and breast-feeding women only if advised by the doctor.
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET should be used with caution in children and your child’s doctor may adjust the dose depending upon child’s age and body weight.
The most common side effects of taking LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET are headache, dizziness, vomiting, stomach pain, nausea, muscle pain and loss of appetite. Consult your doctor if any of the side effects worsen.
Uses Of LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET
- Manage acute uncomplicated malarial infections (caused by plasmodium falciparum) in infants, children and adults
How LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET Works
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET effectively manages malarial infections, where artemether effectively kills the malarial parasites by binding to haem (part of molecules that contains iron which is toxic to malarial parasites) which is produced during the breakdown of haemoglobin. Lumefantrine works by binding to hemin where it manages the formation of a toxic malarial pigment called hemozoin, thereby it manages malarial infection. In addition to this artemether and lumefantrine blocks nucleic acid and protein synthesis in parasite that damages the parasitic cell membrane of plasmodium falciparum which leads to the death of parasite. Thus, it helps in managing the malarial infection.
How to use LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET
Take LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET exactly as advised by your doctor.
For Tablet, Capsule: Swallow LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET with a glass of water. This medicine should be taken with food or drinks rich in fat such as milk. Crush the medicine into powder if your child is unable to swallow the whole medicine.
For Dispersible Tablet: Disperse LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution.
Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of the disease condition.
Side Effects Of LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET
Common
- headache, dizziness
- nausea, vomiting
- stomach pain
- diarrhea
- muscle or joint pain
- difficulty to sleep
- loss of appetite
- cough
- fast heartbeat
- general weakness, tiredness
- involuntary muscle spasms
- abnormal walking (in children above 12 years)
- tingling sensation or numbness of hand and feet
- rashes or itching in the skin
- disturbance in heart rhythm (prolonged QTc interval)
Uncommon
- sleepiness
- decreased skin sensitivity
- inability to coordinate movements
Rare
- allergic reactions
Stop taking LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET and contact your doctor immediately if you experience any of the following side effects:
- swelling of the face, lips, tongue or throat with difficulty in breathing and swallowing
- skin condition with large fluid filled blisters (bullous eruption)
How To Manage Side Effects
Headache:
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Do not consume too much of alcohol. Consult your doctor if the symptom does not improve.
Nausea and vomiting:
Stick to simple meals while taking this medicine. Avoid eating oily, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.
Stomach pain:
Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-manage on your own and consult your doctor if the symptom does not improve.
Diarrhea:
Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhea. Consult your doctor if the symptom does not improve.
Tiredness:
Drink plenty of fluid and eat balanced diet and frequent meals. Do regular minimal exercise and follow regular sleep schedule. Consult your doctor if the symptom does not improve.
Warning & Precautions
Pregnancy
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET is generally not recommended for use during the first trimester of pregnancy. It should be used with caution during second and third trimester of pregnancy only if considered clearly necessary. Consult your doctor before taking LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET.
Breastfeeding
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET should be taken with caution in breast feeding women only if considered clearly necessary. Consult your doctor before taking LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET.
Driving and Using Machines
Do not drive or operate any machines if you experience dizziness, sleepiness or weakness after taking LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET.
Kidney
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET is not recommended for use in patients having severe type of malarial infection affecting the kidneys. It should be taken with caution in patients with severe kidney problems. Consult your doctor before taking LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET.
Liver
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET should be taken with caution in patients with severe liver problems. Consult your doctor before taking LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET.
Allergy
Do not take LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET if you are allergic to Artemether, Lumefantrine or any other ingredients of this medicine.
Lungs
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET is not recommended for use in patients having malaria with pulmonary edema or severe type of malarial infection affecting the lungs. Consult your doctor before taking it.
Heart Disease
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET is not recommended for use in patients with severe heart disease or with heart diseases such as slow heartbeat, changes in the rhythm or rate of the heartbeat or family history of death due to heart problems or born with heart problems. LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET should be taken with caution in patients with variations in ECG (prolongation of QTc interval). Consult doctor before taking LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET.
Others
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET is not recommended for use if you have:
- severe type of malarial infection that has affected the brain
- low levels of electrolytes such as potassium or magnesium in blood
Before taking LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET, inform your doctor if you:
- infected with both the plasmodium falciparum and plasmodium vivax parasites
- feeling worse or if you feel too unwell to eat and drink
Use in pediatrics
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET should be given with caution in children as the dosages of LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET vary in children according to their body weight. So, consult a paediatrician before you give this medicine to your child.
Use in geriatrics
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET can be used in elderly patients. However, consult your doctor before taking this medicine.
Interactions
A. Drug – drug interactions:
Before taking LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used to manage heart rhythm problems (Ex. Flecainide, metoprolol)
- medicines used to manage depression (Ex. imipramine, amitriptyline, clomipramine, St. John’s wort)
- medicine used to manage leprosy or tuberculosis (Ex. rifampicin)
- medicines used to manage bacterial infections (EX. fluroquinolones such as ciprofloxacin, levofloxacin, macrolide antibiotics like azithromycin, erythromycin)
- medicines used to manage fungal infection (Ex. ketoconazole, fluconazole, itraconazole)
- medicines used to manage allergy (Ex. terfenadine, astemizole)
- medicine used to manage stomach disturbance (Ex. cisapride)
- medicines used to manage fits (Ex. carbamazepine, phenytoin)
- medicines used to manage malaria (Ex. atovaquone/proguanil, chloroquine)
- medicines used to manage HIV infection (Ex. indinavir, ritonavir)
- medicine used to manage pregnancy (Ex. Ethinyl estradiol)
B. Drug – Food interactions
Drink grapefruit juice with caution while taking LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET as it may interact with this medicine.
Overdosage:
If you or anyone else accidentally take too much of LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET, consult your doctor immediately or visit a nearby hospital.
Synopsis
| Drug | : | Artemether, Lumefantrine |
| Pharmacological Category | : | Antimalarials |
| Therapeutic Indication | : | Manages acute uncomplicated malaria |
| Dosage Forms | : | Tablet, Dispersible tablet, Injection, Syrup, Oral suspension, Dry Syrup |
More Information
- Keep LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET out of reach of children
- Store LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET at room temperature
FAQs About LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET
What is LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET used for?
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET is used in infants, children and adults for the management of acute uncomplicated malaria (mosquito born disease with symptoms of fever with chills, tiredness, nausea, vomiting, stomach pain) caused by a parasite called plasmodium falciparum.
Does LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET helps to manage malaria?
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET is not used to manage malaria. It is only used to manage malarial infection caused by a parasite called plasmodium falciparum. Consult your doctor for advice before taking this medicine.
Is LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET safe to use in pregnant women?
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET is generally not recommended for use during the first trimester of pregnancy. It should be used with caution during second and third trimester of pregnancy only if considered clearly necessary. Consult your doctor before taking LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET.
Can LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET be used in patients with kidney problems?
LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET is not recommended for use in patients having severe type of malarial infection affecting the kidneys. It should be taken with caution in patients with severe kidney problems. Consult your doctor before taking LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET.
Does LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET cause diarrhea?
Yes, LUMETHER 80 ORANGE FLAVOUR DISPERSIBLE TABLET may cause diarrhea in some individuals. To manage this effect, drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhea. Consult your doctor if the symptom does not improve.
References
1. KD Tripathi. Antimalarial drugs. Essentials of Medical Pharmacology. Eighth edition. 2019. Page: 875-77.
2. Stephan Ehrhardt, Christian G Meyer. Artemether–lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria. NIH. National Library of medicine. National center for Biotechnology Information. PubMed central. October 2009. [Accessed on 3rd November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762439/
3. Novartis Pharmaceuticals. Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria (CALINA). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in March 2020] [Accessed on 3rd November 2022] https://clinicaltrials.gov/ct2/show/NCT04300309
4. Novartis Ireland Limited. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 3rd November 2022] https://www.medicines.org.uk/emc/files/pil.1628.pdf
5. Ajanta Pharma Ltd. Food and Drugs Authority (FDA).[Revised in February 2018] [Accessed on 3rd November 2022] https://fdaghana.gov.gh/img/smpc/Artefan%20(Artemether-Lumefantrine%2060mg-360mg)%20Tablets.pdf
6. Ajanta Pharma Ltd. Artefan 80/480 (Artemether and Lumefantrine). [Revised in March 2019] [Accessed on 3rd November 2022] https://extranet.who.int/pqweb/sites/default/files/MA130part3.pdf
7. Ajanta Pharma Ltd. Artefan 40/240 (Artemether and Lumefantrine). [Revised in March 2019] [Accessed on 3rd November 2022] https://extranet.who.int/pqweb/sites/default/files/MA128part3.pdf
8. Getz pharma ltd. Artheget (Artemether + Lumefantrine). [Accessed on 3rd November 2022] https://getzpharma.com/wp-content/uploads/2016/07/Artheget-Range-Leaflet-Pakistan.pdf
9. Cipla Ltd. Lumet 80 Tablets (Artemether + Lumefantrine). CiplaMed. [Revised in October 2013] [Accessed on 3rd November 2022] https://ciplamed.com/content/lumet-80-tablets
Useful Diagnostic Tests
- Peripheral Smear for Malaria
Author Details
