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Introduction About LUCENTIS 0.5MG INJECTION
LUCENTIS 0.5MG INJECTION is an ophthalmic injection used in the management of severe eye conditions caused due to diabetes, macular degeneration, and macular swelling. It reduces abnormal growth and leakage of blood vessels in the eye that can cause vision loss.
It contains a medicine called Ranibizumab which is an anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the growth and leakage of abnormal blood vessels in the eye(s) that may cause vision loss.
LUCENTIS 0.5MG INJECTION is administered by your eye doctor as a single injection directly into the eye, using a local anesthetic. Before receiving LUCENTIS 0.5MG INJECTION, inform your doctor if you have any eye infections, eye inflammations, cataract, previous history of stroke or any pre-existing eye problems as a precaution. You must inform your doctor before receiving LUCENTIS 0.5MG INJECTION if you are pregnant or breastfeeding as a precaution.
The most common side effects of using LUCENTIS 0.5MG INJECTION are eye redness, irritation, discomfort, a feeling of having some small particles in the eye, increased tear production, dry eyes, sore throat, nasal congestion, runny nose, headache, joint pain, Blurring of vision, Discharge from the eye and Light sensitivity. Talk to your doctor if any of these side effects troubles you.
Uses Of LUCENTIS 0.5MG INJECTION
It is used in the management of following eye diseases such as:
- Diabetes related eye conditions
- Wet age-related macular degeneration
- Macular edema due to retinal vein occlusion or pathological myopia
How LUCENTIS 0.5MG INJECTION Works
Ranibizumab is an injection that works by targeting a specific protein in the eye called vascular endothelial growth factor (VEGF). VEGF can cause abnormal blood vessels to grow under the retina, leading to leakage and vision problems, which are common in conditions like age-related macular degeneration (AMD) and diabetic retinopathy. Ranibizumab binds to VEGF, blocking its activity and preventing these abnormal blood vessels from growing and leaking. This action helps to reduce swelling, slow down vision loss, and in many cases, improve vision in patients with these eye conditions.
How to use LUCENTIS 0.5MG INJECTION
- LUCENTIS 0.5MG INJECTION should be used under medical supervision.
- It will be administered as a single injection into your eye by your eye doctor under a local anaesthetic.
- Your doctor will decide the correct dosage and how many times this medicine should be taken based on your eye condition.
- Do not stop receiving LUCENTIS 0.5MG INJECTION without doctor consultation.
Side Effects Of LUCENTIS 0.5MG INJECTION
Common Side Effects of LUCENTIS 0.5MG INJECTION:
- Eye redness, irritation, discomfort
- A feeling of having some small particles in the eye
- Increased tear production
- Dry eyes
- Increased eye pressure
- Sore throat, nasal congestion, runny nose, headache and joint pain
- Decreased sharpness of vision
- Swelling of some parts of the eye
- Blurring of vision
- Discharge from the eye with itching, redness and swelling
- Light sensitivity
- Urinary tract infection
- Low red blood cells count causing tiredness, breathlessness, dizziness, pale skin
- Cough
- Nausea
Contact your doctor immediately if you experience any of the following side effects after using LUCENTIS 0.5MG INJECTION:
- eye pain or increased discomfort
- worsening eye redness
- eye infections or inflammations
- development of cataracts
- flashes of light with floaters progressing to a temporary loss of sight
Warning & Precautions
Pregnancy
Consult your doctorThere is no proper information regarding the use of Ranibizumab injection in pregnant women. Therefore, LUCENTIS 0.5MG INJECTION should be used in pregnant women only if it is considered necessary.
Women of childbearing potential must use effective contraception during treatment and for at least three further months after the last injection of LUCENTIS 0.5MG INJECTION.
Breastfeeding
ContraindicatedStudies have shown that small amounts of ranibizumab injection may pass into breast milk. Therefore, LUCENTIS 0.5MG INJECTION is not recommended during breast-feeding.
Driving and Using Machines
Use with CautionDo not drive or handle any heavy machinery if you experience any visual disturbances after using LUCENTIS 0.5MG INJECTION. Wait until your vision becomes clear to be on the safer side.
Allergy
ContraindicatedBefore receiving LUCENTIS 0.5MG INJECTION inform your doctor if you are allergic to Ranibizumab
Use In Pediatrics
Consult your doctorThe safety and effectiveness of Ranibizumab injection have not been established in children. Therefore, consult your doctor before using LUCENTIS 0.5MG INJECTION.
Use In Geriatrics
Consult your doctorLUCENTIS 0.5MG INJECTION can be used in elderly patients with dose adjustments.
Others
Before receiving GBNKEYWORD], inform your doctor if you:
- Are having eye infections
- Have intraocular inflammation (severe pain and redness of the eye)
- Have a tear in one of the layers in the back of the eye
- Have cataract
- Have a previous history of eye diseases
- Previously had stroke
Synopsis
| Drug | : | Ranibizumab |
| Pharmacological Category | : | vascular endothelial growth factor blocker |
| Therapeutic Indication | : | Eye conditions |
| Dosage Forms | : | Ophthalmic injection |
More Information
Diabetes-Related Eye Conditions: Diabetes can lead to damage in the tiny blood vessels of the retina, the light-sensitive tissue at the back of the eye. This can cause diabetic retinopathy, where blood vessels may leak fluid or bleed, leading to blurred vision, floaters, or even vision loss if untreated. Diabetic macular edema (DME) is another complication, resulting from fluid buildup in the macula (the central part of the retina), causing swelling and vision impairment.
Wet Age-Related Macular Degeneration (Wet AMD): Wet AMD is a chronic eye condition that causes blurred vision or blind spots due to the growth of abnormal blood vessels under the macula. These vessels may leak fluid or blood, leading to rapid vision loss. It's one of the leading causes of vision impairment in older adults and requires timely treatment to prevent severe vision loss.
Macular Edema Due to Retinal Vein Occlusion or Pathological Myopia: Macular edema is swelling in the macula, often due to retinal vein occlusion (a blockage in the retinal veins) or pathological myopia (severe nearsightedness). Retinal vein occlusion leads to blood and fluid leakage, which can damage the retina and macula, causing vision loss. Pathological myopia, on the other hand, stretches and thins the retina, which may also lead to macular edema and vision problems.
FAQs About LUCENTIS 0.5MG INJECTION
Q: What is LUCENTIS 0.5MG INJECTION used for?
A: LUCENTIS 0.5MG INJECTION is an ophthalmic injection used in the management of severe eye conditions caused due to diabetes, macular degeneration, and macular swelling. It reduces abnormal growth and leakage of blood vessels in the eye that can cause vision loss.
Q: Who can use LUCENTIS 0.5MG INJECTION?
A: LUCENTIS 0.5MG INJECTION is suitable for use in adults and in elderly people who have age related or diabetes related vision problems.
Q: Can LUCENTIS 0.5MG INJECTION reverse vision loss?
A: Studies have shown that Ranibizumab ophthalmic injection helps in improving vision clarity in patients with age related vision decline. However, the complete cure of the eye condition can be determined only by your doctor.
Q: I have cataract. Can I take LUCENTIS 0.5MG INJECTION?
A: If you already have cataract, inform the doctor prior to the administration of LUCENTIS 0.5MG INJECTION. You will decide whether you should take this medicine or not.
Q: How LUCENTIS 0.5MG INJECTION will be administered?
A: LUCENTIS 0.5MG INJECTION should be used under medical supervision. It will be administered as a single injection into your eye by your eye doctor under a local anaesthetic.
Q: Can LUCENTIS 0.5MG INJECTION be taken during pregnancy?
A: There is no proper information regarding the use of Ranibizumab injection in pregnant women. Therefore, LUCENTIS 0.5MG INJECTION should be used in pregnant women only if it is considered necessary. Consult your doctor for advice.
Q: Is LUCENTIS 0.5MG INJECTION safe?
A: LUCENTIS 0.5MG INJECTION is safe at doses prescribed by the physician. Therefore, do not overuse or miss any doses of LUCENTIS 0.5MG INJECTION and inform your doctor about all of pre-existing eye conditions as a precaution. If you experience any worsening eye symptoms, inform your doctor immediately.
Q: Are they any side effects for Ranibizumab injection?
A: Like other medicines, ranibizumab injection also causes certain side effects like eye redness, irritation, discomfort, a feeling of having some small particles in the eye, increased tear production, dry eyes, sore throat, nasal congestion, runny nose, headache, joint pain, Blurring of vision, Discharge from the eye and Light sensitivity. Talk to your doctor if any of these side effects troubles you.
References
- Ranibizumab. StatPearls. National Library of Medicine. National Center for Biotechnology Information. July 2023. [Accessed on 29th October 2024]. click here
- Ranibizumab. Lucentis 10 mg/ml solution for injection in pre-filled syringe. EMC. UK. Novartis Pharmaceuticals UK Ltd. [Revised in February 2023]. [Accessed on 29th October 2024]. click here
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