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Introduction About LIOFEN 25MG TABLET
LIOFEN 25MG TABLET contains Baclofen which belongs to the group of medicines called Muscle relaxants. It is used to manage muscle spasms caused due to cerebral palsy, multiple sclerosis, stroke or due to any other nerve or spinal cord disorders.
Before taking LIOFEN 25MG TABLET inform your doctor if you have diabetes, hypertension or any problems with your lung, liver, kidney or heart. You must also inform your doctor if you have fits, problems in urination, any mental illness or a previous history of alcoholism or drug abuse.
LIOFEN 25MG TABLET should not be used in pregnant or breastfeeding women unless considered necessary by the physician. During management with LIOFEN 25MG TABLET, your doctor will periodically monitor your health condition through several blood tests and urine tests to avoid the risk of unwanted side effects.
LIOFEN 25MG TABLET may causes excessive sleepiness. Therefore, avoid engaging into hazardous activities that requires complete alertness. Do not drive or handle any heavy tools or machines. Also, avoid consumption of alcohol as it may make you feel drowsier.
The most common side effects of taking LIOFEN 25MG TABLET are drowsiness, confusion, weakness and feeling unsteady or shaky. Consult your doctor if any of the symptoms worsen. You must also inform your doctor immediately if you feel extremely sad or depressed along with thoughts of committing suicide after taking LIOFEN 25MG TABLET.
Uses Of LIOFEN 25MG TABLET
- Manage muscle spasms (painful muscle contractions)
How LIOFEN 25MG TABLET Works
LIOFEN 25MG TABLET is a muscle relaxant. It acts by increasing the effects of certain chemical messengers (such as GABA) in the spinal cord that induces muscle relaxation. As a result, it manages muscle twitching, relieves pain caused due to muscle spasms and improves muscle movement.
How to use LIOFEN 25MG TABLET
Take LIOFEN 25MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It is preferably taken with food or milk to avoid nausea.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Do not stop taking LIOFEN 25MG TABLET without consulting your doctor as it may cause withdrawal symptoms such as muscle spasms, increased muscle tightness, fast heart rate, fever, confusion, hallucinations, mood changes, mental disorders, feeling attacked or persecuted or convulsions (fits).
Side Effects Of LIOFEN 25MG TABLET
Common
- nausea, vomiting
- tiredness, sleepiness
- weak limbs, muscle pain
- constipation, diarrhoea, dry mouth
- lack of sleep, nightmares
- confusion, hallucination
- breathing difficulties
- vision problems
- urge to pass urine
- feeling unsteady or shaky
- feeling faint due to low blood pressure
- skin rash, sweating
- increased liver enzymes
Rare
- numbness or tingling in hands or feet
- change in sense of taste
- slurred or slow speech
- sexual problems in men, such as impotence
- convulsions (fits)
Stop taking LIOFEN 25MG TABLET and inform your doctor immediately if you experience any of the following side effects such as:
- feeling extremely depressed with thoughts of harming or killing themselves (suicidal thoughts)
- signs of severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat or tongue causing difficulty in breathing or swallowing)
- uncontrollable muscle spasms affecting the eyes, head, neck or body
- irregular or slow heartbeat, breathing difficulties, chest pain
- fainting or seizures (fits)
- behavioural changes (such as aggression, excitement, confusion, restlessness, agitation, irritability, rages, hallucinations, nightmares)
- difficulty in passing urine, bloody urine, painful urination
How To Manage Side Effects
Constipation
Eat plenty of fiber rich foods such as fresh fruits, vegetables and cereals and drink plenty of water. Exercise more regularly. Consult your doctor if the symptom did not improve.
Nausea And Vomiting
Take LIOFEN 25MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.
Sleepiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling sleepy. Do not consume excessive alcohol, as it could aggravate your sleepiness. Consult your doctor if your sleepiness worsens.
Warning & Precautions
Pregnancy
Monitoring requiredLIOFEN 25MG TABLET is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it.
Breastfeeding
Use with CautionLIOFEN 25MG TABLET should be used with caution in breastfeeding women. Therefore, consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if you feel drowsy, dizzy or problems with your vision after taking LIOFEN 25MG TABLET.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking LIOFEN 25MG TABLET as it may make you feel dizzier or drowsier.
Kidney
Use with CautionLIOFEN 25MG TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
Liver
Use with CautionLIOFEN 25MG TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take LIOFEN 25MG TABLET if you are allergic to Baclofen.
Lungs
Use with CautionLIOFEN 25MG TABLET should be used with caution in patients with lung problems. Therefore, consult your doctor before taking it.
Heart Disease
Use with CautionLIOFEN 25MG TABLET should be used with caution in patients with heart problems. Therefore, consult your doctor before taking it.
Use In Pediatrics
Monitoring requiredLIOFEN 25MG TABLET can be used in children and adolescents aged below 18 years if prescribed by the physician. However, it is not suitable for use in children weighing below 33kg of body weight. Therefore, consult your doctor for advice.
Use In Geriatrics
Use with CautionLIOFEN 25MG TABLET should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
Others
LIOFEN 25MG TABLET is not recommended for use if you:
- have ever had a stomach ulcer
Before taking LIOFEN 25MG TABLET, inform your doctor if you:
- have ever had stroke in the past
- have epilepsy (fits)
- have any mental illness
- have high blood pressure
- have Parkinson’s disease (shaking, stiffness and difficulty with walking or balance)
- have diabetes
- have difficulties in passing urine
- are an alcoholic or have a history of drug abuse or dependence
- are scheduled for any surgery in the upcoming days
Interactions
A. Drug-Drug interactions:
Before taking LIOFEN 25MG TABLET, inform your doctor if you are taking any of the following medicines such as:
- Other muscle relaxants (Ex. tizanidine)
- Antidepressants (Ex. lithium, amitriptyline)
- Antihypertensives (Ex. diltiazem)
- Pain killers (Ex. ibuprofen, morphine)
- Anti-Parkinsonian agents Ex. levodopa or carbidopa)
- Antiallergic medicines (Ex. promethazine)
- Sedatives (Ex. temazepam)
- Antiepileptics (Ex. carbamazepine)
B. Drug-Food interactions:
LIOFEN 25MG TABLET can be taken with food or milk.
Overdosage:
If you or anyone else accidentally took more LIOFEN 25MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include increased drowsiness, difficulties in breathing, feeling faint, muscle weakness, confusion, hallucinations, fits, low blood pressure, slow heartbeat, nausea, vomiting, diarrhoea, excessive saliva production or reflex problems, etc.
Synopsis
| Drug | : | Baclofen |
| Pharmacological Category | : | γ-Aminobutyric acid (GABA) mimetic |
| Therapeutic Indication | : | Muscle Spasms |
| Dosage Forms | : | Tablet, Capsule, Injection |
More Information
Storage
- Keep LIOFEN 25MG TABLET out of reach of children
- Store LIOFEN 25MG TABLET below 25°C
FAQs About LIOFEN 25MG TABLET
Q: What is the use of LIOFEN 25MG TABLET?
A: LIOFEN 25MG TABLET is used to manage muscle spasms caused due to cerebral palsy, multiple sclerosis, stroke or due to any other nerve or spinal cord disorders.
Q: How LIOFEN 25MG TABLET works?
A: LIOFEN 25MG TABLET is a muscle relaxant. It acts by increasing the effects of certain chemical messengers (such as GABA) in the spinal cord that induces muscle relaxation. As a result, it manages muscle twitching, relieves pain caused due to muscle spasms and improves muscle movement.
Q: How to take LIOFEN 25MG TABLET?
A: Take LIOFEN 25MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not chew or crush the medicine. It is preferably taken with meals or milk to avoid nausea.
Q: What is the best time to take LIOFEN 25MG TABLET?
A: LIOFEN 25MG TABLET can be taken during bedtime or while performing activities such as washing, dressing and shaving etc. However, your doctor will decide the best time to take LIOFEN 25MG TABLET.
Q: Can I stop taking LIOFEN 25MG TABLET once I started feeling better?
A: No. Do not stop taking LIOFEN 25MG TABLET without consulting your doctor as it may make your symptoms re-appear once again or can cause withdrawal symptoms such as increased muscle tightness, fast heart rate, fever, confusion, hallucinations or fits.
Q: Can I take LIOFEN 25MG TABLET daily?
A: Take LIOFEN 25MG TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take LIOFEN 25MG TABLET every day or not.
Q: Will taking a higher dose of LIOFEN 25MG TABLET be more effective?
A: No. Taking a higher dose of LIOFEN 25MG TABLET will not be effective rather it would be making you drowsier. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Q: What to do if I forgot to take a dose of LIOFEN 25MG TABLET?
A: If you forgot to take a dose of LIOFEN 25MG TABLET, take it as soon as you remember. However, if it is time for the next dose of LIOFEN 25MG TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of LIOFEN 25MG TABLET to compensate the missed ones. Consult your doctor for advice.
Q: What are the side effects of LIOFEN 25MG TABLET?
A: The most common side effects of taking LIOFEN 25MG TABLET are drowsiness, confusion, weakness and feeling unsteady or shaky. Consult your doctor if any of the symptoms worsen.
Q: Is LIOFEN 25MG TABLET safe to use in children?
A: LIOFEN 25MG TABLET can be used in children and adolescents aged below 18 years if prescribed by the physician. However, it is not suitable for use in children weighing below 33kg of body weight. Therefore, consult your doctor for advice.
Q: What precautions do I need to follow while taking LIOFEN 25MG TABLET?
A: Patients taking LIOFEN 25MG TABLET must inform their doctor about their pre-existing disease conditions like stomach ulcers, kidney, heart or liver problems. Patients should also inform if they have diabetes, hypertension, fits, any mental illness, history of alcoholism or if they are pregnant or breast-feeding. Avoid alcohol consumption. Consult your doctor immediately if you feel extremely depressed with thoughts of committing suicide after taking LIOFEN 25MG TABLET.
Q: Who should not take LIOFEN 25MG TABLET?
A: LIOFEN 25MG TABLET not recommended for use in patients who are allergic to baclofen. It is also not suitable for use in patients with stomach ulcer or during pregnancy. Therefore, consult your doctor for advice.
Q: Does LIOFEN 25MG TABLET make me feel sleepy?
A: LIOFEN 25MG TABLET may causes excessive sleepiness. Therefore, restrict yourself from engaging into hazardous activities that requires complete alertness. Do not drive or handle any heavy tools or machines. Also, avoid consumption of alcohol as it may make you feel drowsier. Consult your doctor if sleepiness worsens.
Q: Can I consume alcohol while taking LIOFEN 25MG TABLET?
A: Avoid consumption of alcohol while taking LIOFEN 25MG TABLET as it might make you feel dizzier and drowsier.
Q: Is LIOFEN 25MG TABLET safe to use in diabetic patients?
A: LIOFEN 25MG TABLET may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before taking LIOFEN 25MG TABLET as a precaution. Your doctor will closely monitor you blood sugar levels to avoid the risk of side effects.
Q: Can LIOFEN 25MG TABLET be taken during pregnancy?
A: LIOFEN 25MG TABLET should be used during pregnancy only if considered necessary by the physician. Therefore, consult your doctor before taking it.
Q: Can the use of LIOFEN 25MG TABLET affect the liver?
A: Yes. LIOFEN 25MG TABLET may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before taking it.
Q: Can the use of LIOFEN 25MG TABLET affect my sexual life?
A: LIOFEN 25MG TABLET may rarely cause problems in erection and ejaculation in some individuals. Consult your doctor if it troubles you.
References
1. KD. Tripathi. Drugs Acting on Peripheral (Somatic) Nervous System. Essentials of Medical Pharmacology. Seventh edition. 2013. Page-358.
2. Shirin Ghanavatian; Armen Derian. Baclofen. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. May 2022. [Accessed on 14th August 2024] https://www.ncbi.nlm.nih.gov/books/NBK526037/
3. Per Ertzgaard, MD, Claudia Campo, MS and Alessandra Calabrese, PhD. FFICACY AND SAFETY OF ORAL BACLOFEN IN THE MANAGEMENT OF SPASTICITY: A RATIONALE FOR INTRATHECAL BACLOFEN. Journal of Rehabilitation Medicine. January 2017. [Accessed on 14th August 2024] https://www.medicaljournals.se/jrm/content/html/10.2340/16501977-2211#:~:text=Baclofen%20was%20significantly%20more%20effective,25%2C%2026%2C%2030)
4. Accord. Electronic Medicines Compendium (EMC). [Revised in November 2020] [Accessed on 14th August 2024] https://www.medicines.org.uk/emc/files/pil.5728.pdf
5. NOVARTIS Pharmaceuticals Australia Pty Limited. Lioresal 10 and 25 mg. [Revised in March 2022]. [Accessed on 14th August 2024] https://www.guildlink.com.au/gc/ws/nv/cmi.cfm?product=nvclrsor10213
6. Camber Pharmaceuticals, Inc. Baclofen Tablet. Dailymed.com. [Revised in October 2021]. [Accessed on 14th August 2024] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ce48b5de-92d3-424e-ba70-c1f2edb28f66
7. Central Drugs Standard Control Organisation. Baclofen tablets. Baclofen ER Capsule 10 mg/50 mg (Additional Strength). Baclofen E.R capsule (30mg). [Accessed on 14th August 2024] https://cdscoonline.gov.in/CDSCO/Drugs
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