LINVAS 4mg Tablet 10's

Introduction About LINVAS 4MG TABLET

LINVAS 4MG TABLET contains Saroglitazar which belongs to the group of medicines called Antidiabetic agents. It is indicated for the management of diabetic dyslipidaemia and hypertriglyceridemia (high levels of triglycerides) with Type 2 diabetes mellitus which is not controlled by statin therapy.

Diabetic Dyslipidaemia refers to a condition in which there are elevated triglycerides and LDL cholesterol, low HDL cholesterol, and major presence of small LDL particles. Your doctor may ask you to undergo certain diagnostic tests before starting the management with this medicine. Along with LINVAS 4MG TABLET, your doctor might ask you to make certain lifestyle changes such as eating healthy, adequate sleep, weight and stress management, quitting smoking and alcohol.

LINVAS 4MG TABLET should be used with caution in patients having liver, kidney or heart disease (with episodic congestive heart failure) and history of muscle diseases. LINVAS 4MG TABLET should be used with caution in pregnant women and is not recommended for use in breast-feeding women.

Safety and effectiveness of this medicine has not been established in children, hence, ask for your doctor’s advice before taking. LINVAS 4MG TABLET should be used with caution in elderly patients. The most common side effects of taking LINVAS 4MG TABLET are gastritis, weakness, and fever. Consult your doctor if any of the above side effects does not improve or persists for a longer duration.

Uses Of LINVAS 4MG TABLET

It is used to manage:

• diabetic dyslipidaemia
• hypertriglyceridemia (high levels of triglycerides) with Type 2 diabetes mellitus which is not controlled by statin therapy

How LINVAS 4MG TABLET Works

LINVAS 4MG TABLET influences glucose metabolism as well as fat metabolism. It acts on certain receptors and helps in lowering high blood triglycerides as well as the glucose levels in the blood and improves insulin resistance. It acts on the liver and increases the degradation of lipids (fats) and decreases their formation as well hence, resulting in reduced triglycerides.

How to use LINVAS 4MG TABLET

Take LINVAS 4MG TABLET as advised by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, condition, and body weight.

Side Effects Of LINVAS 4MG TABLET

Warning & Precautions

Pregnancy

Use with Caution

LINVAS 4MG TABLET should be used with caution in pregnant women or women planning to have a baby. Consult with your doctor before taking it.

Breastfeeding

Contraindicated

LINVAS 4MG TABLET is not recommended for use in breastfeeding women as it is not known if it passes through the breast milk. Consult your doctor before taking it.

Kidney

Use with Caution

LINVAS 4MG TABLET should be used with caution in patients with abnormal kidney function. Consult your doctor before taking it.

Liver

Use with Caution

LINVAS 4MG TABLET should be used with caution in patients with abnormal liver function. Consult your doctor before taking.

Allergy

Contraindicated

Do not take LINVAS 4MG TABLET if you are allergic to Saroglitazar or any other ingredients of this medicine.

Heart Disease

Use with Caution

LINVAS 4MG TABLET should be taken with caution in patients with type 2 diabetes mellitus having heart diseases with episodic congestive heart failure. Consult your doctor before taking.

Use In Pediatrics

Consult your doctor

Safety and effectiveness of LINVAS 4MG TABLET has not been established in children. Consult with your doctor before taking.

Use In Geriatrics

Use with Caution

LINVAS 4MG TABLET should be used with caution in elderly patients. Consult with your doctor before taking.

Interactions

A. Drug-Drug Interactions:

Before taking LINVAS 4MG TABLET, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, non-prescription or any herbal medicine.

Overdosage:

If you or anyone else accidentally takes too much of LINVAS 4MG TABLET, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep LINVAS 4MG TABLET out of reach of children
• Store at room temperature below 25°C

FAQs About LINVAS 4MG TABLET

Q: What is LINVAS 4MG TABLET and why is it prescribed?

A: LINVAS 4MG TABLET contains Saroglitazar which belongs to the group of medicines called Antidiabetics. It is used to manage Diabetic dyslipidemia and Hypertriglyceridemia (high levels of triglycerides) with Type 2 diabetes mellitus which is not controlled by statin therapy.

Q: Can LINVAS 4MG TABLET be given to pregnant and breast-feeding women?

A: LINVAS 4MG TABLET should be used with caution in pregnant women only if the potential benefits are more than the risks involved. It is not recommended for use in breastfeeding women as it is not known if it passes through breastmilk. Consult your doctor before taking it.

Q: Can LINVAS 4MG TABLET cause weight gain?

A: Although during the clinical studies, no significant weight gain and edema was reported with LINVAS 4MG TABLET, patients who experience rapid increase in weight should be assessed for fluid accumulation and volume-related events such as excessive edema and congestive heart failure. Consult your doctor for advice.

Q: How does LINVAS 4MG TABLET work?

A: LINVAS 4MG TABLET influences glucose metabolism as well as fat metabolism. It acts on certain receptors and helps in lowering high blood triglycerides as well as the glucose levels in the blood and improves insulin resistance. It acts on the liver and increases the degradation of lipids (fats) and decreases their formation as well hence, resulting in reduced triglycerides.

Q: Can LINVAS 4MG TABLET be taken by patients having heart diseases?

A: LINVAS 4MG TABLET should be taken with caution in patients with type 2 diabetes mellitus having heart diseases with episodic congestive heart failure. Consult your doctor before taking.

Q: Can LINVAS 4MG TABLET interact with other medical conditions?

A: Before starting LINVAS 4MG TABLET, inform your healthcare provider about any medical conditions you have, especially gastrointestinal disorders such as bowel obstruction or severe constipation. It should be used with caution in patients with these conditions.

Q: Can I drink alcohol while taking LINVAS 4MG TABLET?

A: It is important to consult your healthcare provider regarding alcohol consumption while taking LINVAS 4MG TABLET, as alcohol may interact with certain medications and could affect the kidney function.

Q: What should I do if I experience severe side effects while taking LINVAS 4MG TABLET?

A: If you experience severe side effects such as difficulty breathing, severe abdominal pain, or allergic reactions (e.g. rash, itching, swelling), seek immediate medical attention and discontinue the use. It is important to report any adverse reactions to your healthcare provider.

Q: Can I stop taking LINVAS 4MG TABLET if my phosphate levels improve?

A: Do not stop taking LINVAS 4MG TABLET without consulting your healthcare provider, even if your phosphate levels improve. Stopping the medication abruptly could cause your phosphate levels to rise again. Your healthcare provider will determine the appropriate duration of management based on your condition.

Q: How long does it take for LINVAS 4MG TABLET to start working?

A: The onset of action of LINVAS 4MG TABLET may vary from person to person. Some individuals may start to see a reduction in phosphate levels within a few days of starting management, while others may require several weeks. It is important to monitor phosphate levels regularly as directed by your healthcare provider.

References

1. KD. Tripathi. Hypolipidemic Drugs. Essentials of medical pharmacology. Eighth edition. 2018. Page – 688.

2. Shaival Chandalia. Hydroxychloroquine: Old wine in a new bottle & Saroglitazar: New Kid on the Block. Association of Diabetes Educators. Journal of Diabetes Education. March 2019. [Accessed on 23rd June 2022] https://www.diabeteseducatorsindia.com/uploads/Journal/pdfs/vol7-no1-jan-mar-2019-30.pdf

3. Mukul R Jain, Suresh R Giri, Chitrang Trivedi, Bibhuti Bhoi, Akshyaya Rath, Geeta Vanage, Purvi Vyas, Ramchandra Ranvir, Pankaj R Patel. Saroglitazar, a novel PPARα/γ agonist with predominant PPARα activity, shows lipid-lowering and insulin-sensitizing effects in preclinical models. NIH National library of medicine. National centre for biotechnology information. Pubmed.gov 2015. [Accessed on 23rd June 2022] https://pubmed.ncbi.nlm.nih.gov/26171220/

4. Cadila Healthcare Limited. Lipaglyn. [Accessed on 23rd June 2022] http://lipaglyn.com/downloads/Lipaglyn_Product_Monograph.pdf, http://www.lipaglyn.com/downloads/Lipaglyn_PI_Booklet.pdf

Useful Diagnostic Tests

• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
• Blood Glucose Fasting (FBS)
• Post Prandial Blood Sugar (PPBS)
• Insulin-Fasting
• Netmeds Diabetic Checkup
• Advance Diabetes Monitoring (Senior Female)
• Jaanch Diabetic Profile Basic

Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)

Last updated on 26 Feb 2024 | 11:51 AM(IST)