LACOTAB Syrup 200ml
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Introduction About LACOTAB SYRUP
LACOTAB SYRUP contains Lacosamide which belongs to the group of medicines called Antiepileptics. It is used to manage a certain type of epilepsy characterised by the occurrence of partial onset seizure with or without secondary generalisation.
In this type of epilepsy, fits first affect only one side of your brain. However, these may then spread to larger areas on both sides of your brain. It may be used on its own or with other antiepileptic medicines.
Epilepsy is a neurological disorder of the central nervous system in which the brain activity becomes abnormal, causing seizures or periods of unusual behavior, sensations and sometimes loss of awareness.
Before taking LACOTAB SYRUP, inform your doctor if you have or ever had a certain type of heartbeat problem called second or third-degree AV block.
LACOTAB SYRUP is not recommended to use among women who are pregnant or breastfeeding. Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Consult your doctor before taking.
The most common side effects of taking LACOTAB SYRUP are headache, feeling dizzy or sick, nausea and double vision. Contact your doctor if any of the above symptoms worsen.
Uses Of LACOTAB SYRUP
- Used as an adjunctive management of partial onset seizures in patients above 17 years of age
How LACOTAB SYRUP Works
LACOTAB SYRUP works slowly by inactivating the sodium gated channels, which decreases the abnormal and excessive activity of the nerve cells in the brain and controls seizures or fits.
How to use LACOTAB SYRUP
Take LACOTAB SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of LACOTAB SYRUP
Common
- headache
- nausea
- double vision
- myoclonic seizures (short jerks of a muscle or group of muscles)
- difficulties in coordinating movements or walking
- problems in keeping balance, tremors, tingling or muscle spasms, falling easily and getting bruises
- troubles with memory, thinking or finding words, confusion
- blurred vision, rapid and uncontrollable movements of the eyes
- vertigo
- vomiting, dry mouth, constipation, indigestion, excessive gas in the stomach or bowel, diarrhea
- reduced sensitivity or feeling, difficulty in articulating words, disturbance in attention
- noise in the ear such as buzzing, ringing or whistling
- irritability, trouble sleeping, depression
- sleepiness, tiredness or weakness
- itching, rash
- runny nose, fever, sore throat, eating less than usual (in children)
Uncommon
- hallucinations
- blood tests might show abnormal liver function, liver injury
- self-harming thoughts
- feeling angry or agitated
- abnormal thinking or losing touch with reality
- swelling of the face, throat, hands, feet, ankles or lower legs and hives
- feeling sleepy or lacking in energy
How To Manage Side Effects
Nausea or Vomiting:
Take this medicine with or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods.
Diarrhea:
Drink a lot of fluids such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
Constipation:
Eat plenty of fiber-rich foods such as fresh fruits, vegetables and cereals and drink plenty of water. Exercise more regularly.
Warning & Precautions
Pregnancy
LACOTAB SYRUP is not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it.
Breastfeeding
LACOTAB SYRUP is generally not recommended for use in breastfeeding women as it may pass through breast milk. Consult your doctor before taking it.
Driving and Using Machines
Do not drive or operate any machines if you feel dizzy or blurred vision after taking LACOTAB SYRUP.
Alcohol
Avoid consumption of alcohol while taking LACOTAB SYRUP. Consult your doctor for advice.
Kidney
LACOTAB SYRUP should be used with caution in patients with kidney problems. Consult your doctor before taking it.
Liver
LACOTAB SYRUP should be used with caution in patients with liver problems. Consult your doctor before taking it.
Allergy
Do not take LACOTAB SYRUP if you are allergic to Lacosamide or any of the other ingredients of the medicine.
Heart Disease
LACOTAB SYRUP is not recommended for use in patients with second or third-degree AV block and LACOTAB SYRUP should be used with caution in patients with heart disease like AV block, atrial fibrillation, atrial flutter, heart failure, heart attack. Consult your doctor before taking it.
Others
Before taking LACOTAB SYRUP, inform your doctor if you:
- self-harming thoughts
- often dizzy or fall over
Use in pediatrics:
LACOTAB SYRUP is not recommended for use in children aged under 4 years. Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Consult your doctor before taking it.
Use in geriatrics:
LACOTAB SYRUP should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking it.
Interactions
A. Drug-Drug interactions:
Before taking LACOTAB SYRUP, inform your doctor if you are taking any of the following medicine:
- medicines used to manage heart problems
- medicines used to manage epilepsy or pain (Ex. carbamazepine, lamotrigine or pregabalin)
- medicines used for fungal infections (Ex. fluconazole, itraconazole or ketoconazole)
- medicine used to manage HIV (Ex. ritonavir)
- medicines used to manage bacterial infections (Ex. clarithromycin or rifampicin)
- herbal medicine used to manage mild anxiety and depression (Ex. St. John’s wort)
Overdosage:
If you or anyone else accidentally takes too much of LACOTAB SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are dizziness, nausea, vomiting, fits (seizures), heartbeat problems such as a slow, fast or irregular heartbeat or a fall in blood pressure with rapid heartbeat and sweating.
Synopsis
| Drug | : | Lacosamide |
| Pharmacological Category | : | Antiepileptics |
| Therapeutic Indication | : | Epilepsy |
| Dosage Forms | : | Tablet, Injection, Syrup |
More Information
- Keep LACOTAB SYRUP out of reach of children
- Store at a temperature not exceeding 30°C
FAQs About LACOTAB SYRUP
What are the symptoms of overdose of LACOTAB SYRUP?
Symptoms of overdose of LACOTAB SYRUP are dizziness, nausea, vomiting, fits (seizures), heartbeat problems such as a slow, fast or irregular heartbeat. Consult your doctor immediately if you experience these unusual reactions.
How to take LACOTAB SYRUP?
Take LACOTAB SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Is it safe to use LACOTAB SYRUP in patients with kidney problems?
LACOTAB SYRUP should be used with caution in patients with kidney problems. Consult your doctor before taking it.
How do LACOTAB SYRUP work?
LACOTAB SYRUP works slowly by inactivating the sodium gated channels, which decreases the abnormal and excessive activity of the nerve cells in the brain and controls seizures or fits.
Is it safe to take LACOTAB SYRUP during pregnancy?
LACOTAB SYRUP is generally not recommended to use in pregnant women unless clearly considered necessary. Consult your doctor before taking it.
What are the common side effects of LACOTAB SYRUP?
The common side effects of LACOTAB SYRUP are headache, feeling dizzy or sick (nausea) and double vision (diplopia). Consult your doctor for advice.
References
1. Misty D. Smith, Cameron S. Metcalf and Karen S. Wilcox. Pharmacotherapy of the Epilepsies. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018 Page – 303-326.
2. Liyan Hou, Bingjie Peng, Defu Zhang, Jingjing Yang, Ying Wang, Li Tong, Sheng Li, Qingshan Wang1 and Jie Zhao. Clinical Efficacy and Safety of Lacosamide as an Adjunctive Treatment in Adults With Refractory Epilepsy. Frontiers in neurology. December 2021. [Accessed on 21st May] https://www.frontiersin.org/articles/10.3389/fneur.2021.712717/full
3. Jon Allard, William Henley, Brendan Mclean, Sunil Ram, Manny Bagary, Rohit Shankar. Lacosamide in the general population and in people with intellectual disability: Similar responses? European Journal of Epilepsy. March 2020. [Accessed on 21st May] https://www.seizure-journal.com/article/S1059-1311(20)30054-6/fulltext
4. G. L. Krauss. Lacosamide for the treatment of epilepsy. Taylor and Francis online. June 2011. [Accessed on 21st May] https://www.tandfonline.com/doi/full/10.3109/07853890.2011.603700
5. Torrent pharmaceutical LTD. [Revised in April 2021] [Accessed on 21st May] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2867.pdf
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