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Introduction About KOLA 20MG TABLET
KOLA 20MG TABLET is used in the management of schizophrenia and severe manic episodes of bipolar disorders and its recurrence. It contains Olanzapine which belongs to group of medicines known as Antipsychotics. It works by blocking certain brain receptors for dopamine and serotonin, which helps to reduce symptoms like hallucinations and mood swings in conditions like schizophrenia and bipolar disorder.
Along with this management, your doctor might ask you to make certain lifestyle changes, such as eating a healthy diet, regular exercise and quitting alcohol. Prior to the management, your doctor may want you to take several blood tests to understand the existing condition. Avoid consumption of alcohol during management with KOLA 20MG TABLET as it can make you feel drowsy. KOLA 20MG TABLET is not recommended for use in patients previously diagnosed with eye problems like glaucoma or dementia in elderly. Before taking KOLA 20MG TABLET, inform your doctor if you have a history of blood clotting, stroke, Parkinson’s disease, prostate, intestine, heart, liver or kidney disease, diabetes, and seizures.
KOLA 20MG TABLET should be used with caution among women who are pregnant. It is not recommended for use in breastfeeding women and in children and adolescents less than 18 years of age. KOLA 20MG TABLET should be used with caution in elderly patients with dementia. The most common side effects are changes in the levels of some blood cells, weight gain, sleepiness and feeling dizzy.
Uses Of KOLA 20MG TABLET
It is used in the management of the psychotic conditions such as:
- Schizophrenia
- Severe manic episodes of bipolar disorder and its recurrence
How KOLA 20MG TABLET Works
KOLA 20MG TABLET contains Olanzapine which belongs to antipsychotics that works by altering the activity of certain chemicals in the brain, particularly dopamine and serotonin. It blocks receptors for these chemicals, which helps to reduce symptoms like hallucinations, delusions, and mood swings in conditions like schizophrenia and bipolar disorder. By balancing these neurotransmitters, olanzapine helps stabilize mood, improve thinking, and reduce agitation.
How to use KOLA 20MG TABLET
- For Tablet: Swallow the medicine with a glass of water. Do not crush or chew the medicine
- For Mouth Dissolving or Orally disintegrating tablet: Place the medicine inside your mouth and allow it to dissolve completely. Do not swallow or chew the medicine
- For Dispersible Tablet (DT): Drop the medicine in a glass of water and allow it to dissolve. Consume the mixture once the medicine dissolves completely
- Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
- Continue to take KOLA 20MG TABLET for the stipulated duration prescribed by your doctor to achieve better results
Side Effects Of KOLA 20MG TABLET
Common side effects of KOLA 20MG TABLET:
- weight gain
- sleepiness
- increases in levels of prolactin in the blood
- changes in the levels of some blood cells
- feel dizzy (with a slow heart rate), especially while getting up from a lying or sitting position
- restlessness, tremor, unusual movements
- constipation
- dry mouth
- rashes
- loss of strength, extreme tiredness, feeling more hungry
- swelling of the hands, ankles, or feet
- fever, joint pain
- sexual dysfunction
- seizures, muscle stiffness
- syndrome of restless legs, problems with speech (stuttering)
- memory loss or forgetfulness
- hair loss
- changes in breasts in males and females like an abnormal production of breast milk or abnormal growth
Stop taking KOLA 20MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- unusual movement of face or tongue
- blood clots in the veins especially in the legs (swelling, pain, and redness in the leg), which may travel through blood vessels to the lungs causing chest pain and difficulty in breathing
- fever, faster breathing, sweating, muscle stiffness and drowsiness
Warning & Precautions

Pregnancy
Use with CautionKOLA 20MG TABLET should be used with caution in pregnant women.

Breastfeeding
ContraindicatedKOLA 20MG TABLET is not recommended for use in breastfeeding women as it can pass through breast milk.

Driving and Using Machines
Use with CautionDo not drive and use machines while taking KOLA 20MG TABLET as it can make you feel drowsy.

Alcohol
ContraindicatedDo not drink alcohol while taking KOLA 20MG TABLET as it can make you feel drowsy.

Kidney
Use with CautionKOLA 20MG TABLET should be used with caution in patients with kidney disease.

Liver
Use with CautionKOLA 20MG TABLET should be used with caution in patients with liver disease.

Allergy
ContraindicatedDo not take KOLA 20MG TABLET if you are allergic to Olanzapine or any other ingredients of this medicine.

Heart Disease
Use with CautionKOLA 20MG TABLET should be used with caution in patients with heart disease.

Use In Pediatrics
ContraindicatedKOLA 20MG TABLET is not recommended for children and adolescents under 18 years of age.

Use In Geriatrics
Consult your doctorKOLA 20MG TABLET should be used with caution in elderly patients. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Constant monitoring on blood pressure, blood sugar levels and cholesterol levels is recommended in elderly patients. It is not suitable for elders with dementia.
Others
It is not recommended for use if you:
- have been previously diagnosed with eye problems such as certain kinds of glaucoma
- have dementia (especially in elderly patients)
Before taking the medicine, inform your doctor if you:
- you or your family has a history of blood clots or blood disorders
- have a stroke or mini stroke
- have Parkinson’s disease
- have prostate problems, blocked intestine
- have diabetes
- have seizures
- have salt depletion because of prolonged severe diarrhea and vomiting
- are intolerant to some sugar
- have phenylketonuria (increase phenylalanine in blood)
Interactions
A. Drug-Drug interactions:
Before taking KOLA 20MG TABLET, inform your doctor if you are taking any of the following medicine:
- diuretics
- antidepressants
- tranquillizers
- antiparkinsonian agents (Ex. carbamazepine, fluvoxamine, or ciprofloxacin)
Overdosage:
If you or anyone else accidentally takes too much of KOLA 20MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are rapid beating of the heart, agitation, problems with speech, unusual movements (especially of the face or tongue), reduced level of consciousness, acute confusion, seizures.
Synopsis
Drug | : | Olanzapine |
Pharmacological Category | : | Antipsychotics |
Therapeutic Indication | : | Schizophrenia, Manic episodes, Bipolar disorder |
Dosage Forms | : | Tablet, Orally disintegrating tablet, Mouth dissolving Tablet |
More Information
FAQs About KOLA 20MG TABLET
Q: Is it safe to drink alcohol while taking KOLA 20MG TABLET?
A: Yes, avoid alcohol while taking KOLA 20MG TABLET since it may cause more drowsiness.
Q: Can I stop taking KOLA 20MG TABLET?
A: Do not stop taking KOLA 20MG TABLET just because you feel better. It is important that you should take for as long as your doctor tells you. If you suddenly stop taking KOLA 20MG TABLET symptoms such as sweating, unable to sleep, tremor, anxiety or nausea and vomiting might occur.
Q: Is KOLA 20MG TABLET a sleeping pill?
A: No. KOLA 20MG TABLET is an antipsychotic used to manage schizophrenia and bipolar disorder (manic depressive disorder). It causes episodes of depression, mania, and other abnormal moods.
Q: Can KOLA 20MG TABLET be taken during pregnancy?
A: KOLA 20MG TABLET should be avoided during pregnancy and should only be given if benefits outweigh the risk. Using it in last 3 months of pregnancy may cause unwanted symptoms in the unborn baby like shaking, muscle stiffness and/or weakness, sleepiness, agitation, breathing problems, and difficulty in feeding.
References
1. K D Tripathi. Drugs Used in Mental Illness: Antipsychotic and Antimanic Drugs. Essentials of Medical Pharmacology. Eighth Edition. 2019. Page –469.
2. Olanzapine. StatPearls. National Center for Biotecnology Information. National Library of Medicine. NCBI. PubMed Central. [Revised in August 2023] [Accessed on 21st August 2024] click here
3. Olanzapine 2.5, 5, 7.5, 10, 15, 20 mg Tablet, Orodispersible tablet. EMC. UK. Sun Pharmaceutical Industries Europe B.V. [Revised in May 2020] [Accessed on 21st August 2024] click here