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Introduction About KEFLOR DT 125MG TABLET
KEFLOR DT 125MG TABLET contains Cefaclor which belongs to the group of medicines called Antibiotics. It is used to manage bacterial infections of the respiratory tract (Ex. tonsillitis, pharyngitis and bronchitis), lungs (pneumonia) and sinuses (sinusitis).
KEFLOR DT 125MG TABLET can also be used to manage infections of middle ear (otitis media), skin and soft tissue (Ex. muscle), urinary bladder (Ex. cystitis) and reproductive tract (Ex. gonococcal urethritis). Symptoms of bacterial infections generally include fever, extreme tiredness, swollen lymph nodes in the neck, armpits, groin or elsewhere, headache, nausea or vomiting.
Before taking KEFLOR DT 125MG TABLET, inform your doctor if you have any liver, kidney or gastrointestinal problems. KEFLOR DT 125MG TABLET should be used in pregnant women only if your doctor finds it clearly necessary. KEFLOR DT 125MG TABLET should be used with caution in breastfeeding woman. Safety and efficacy of KEFLOR DT 125MG TABLET in infants (less than one month of age) have not been established so, consult your child’s doctor for advice.
The most common side effects of taking KEFLOR DT 125MG TABLET are gastrointestinal symptoms like diarrhoea, itching in genital area, moniliasis (fungal infection), vaginitis (vaginal inflammation with pain, discharge and itchiness), etc. Consult your doctor if any of the symptoms worsen or does not improve.
Uses Of KEFLOR DT 125MG TABLET
Manages bacterial infections that occur in:
- respiratory tract (Ex. tonsillitis, pharyngitis and bronchitis)
- lung (pneumonia)
- sinuses (sinusitis)
- middle ear (otitis media)
- skin and soft tissue (Ex. muscle)
- urinary bladder (Ex. cystitis)
- and reproductive tract (Ex. gonococcal urethritis)
How KEFLOR DT 125MG TABLET Works
KEFLOR DT 125MG TABLET effectively kills the bacteria that causes infection by inactivating certain proteins (penicillin binding proteins) which are necessary for the bacterial cell wall integrity and strength, thereby damaging the cell wall and resulting in bacterial cell death.
How to use KEFLOR DT 125MG TABLET
Always take KEFLOR DT 125MG TABLET as directed by your physician.
For Tablet, Capsule: Swallow KEFLOR DT 125MG TABLET as whole with a glass of water. Do not crush or chew it.
For Dispersible Tablet: Disperse KEFLOR DT 125MG TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Continue to take KEFLOR DT 125MG TABLET for the stipulated duration prescribed by your doctor to achieve better results.
Side Effects Of KEFLOR DT 125MG TABLET
Common
- gastrointestinal symptoms like diarrhoea
- high eosinophil count in blood (fever, night sweats, swelling, weakness)
- itching in genital area, moniliasis (fungal infection) or vaginitis (vaginal inflammation with pain, discharge and itchiness)
- increased levels of certain liver enzymes
Uncommon
- itching, hives
- signs of serum-sickness-like reactions including erythema multiforme, rashes and other skin manifestations which is accompanied by joint pain with or without fever
Rare
- nausea, vomiting
- hypersensitivity reactions like serious skin rashes including Stevens-Johnson syndrome and toxic epidermal necrolysis characterized by reddish target-like macules or circular patch, skin peeling, ulcers of mouth, throat, nose, genitals and eyes along with fever and flu-like symptoms
- anaphylaxis reaction (life threatening allergic condition)
- low blood platelet count (easy bleeding or bruising)
- reversible interstitial nephritis (a kidney disease causing loss of appetite, decreased urinary output, fatigue)
- reversible hyperactivity, nervousness, agitation, inability to sleep, confusion, hypertonia or muscle stiffness, hallucinations, dizziness or drowsiness
- blood disorders (Ex. aplastic anemia, haemolytic anemia, agranulocytosis, reversible neutropenia)
Stop taking KEFLOR DT 125MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- allergic reaction
- diarrhea or colitis
- fits
How To Manage Side Effects
Nausea or Vomiting:
Take KEFLOR DT 125MG TABLET with or just after meals. Stick to simple meals. Try to avoid oil rich or spicy foods, sugary snacks and aerated drinks. Avoid drinking too much liquid or water along with your meals and slowly drink in between meals. If symptom persists, contact your doctor.
Diarrhoea:
Drinking plenty of water and other electrolyte balanced fluids (like diluted fruit juices, broths, sports drinks and caffeine-free sodas) will help with hydration. Try to eat less high-fat foods, like meat, eggs and cheese. Exercise more regularly. If symptom persists, contact your doctor.
Dizziness:
Lie or sit down immediately when you feel dizzy. If you have a spinning sensation, lie in a dark and quite place with eyes closed. Try to avoid vehicle driving. If symptom persists, contact your doctor.
Warning & Precautions
Pregnancy
KEFLOR DT 125MG TABLET should be used in pregnant woman only if clearly necessary. Consult your doctor before taking it.
Breastfeeding
KEFLOR DT 125MG TABLET should be used with caution in breastfeeding woman as some of it may pass into the breast milk. Consult your doctor for advice.
Driving and Using Machines
KEFLOR DT 125MG TABLET is presumed to be safe or unlikely to produce an effect. However, consult your doctor for advice.
Kidney
KEFLOR DT 125MG TABLET should be sued with caution in patients having markedly impaired kidney function. Consult your doctor before taking it.
Liver
KEFLOR DT 125MG TABLET should be used with caution in patients having liver disease. Consult your doctor before taking it.
Allergy
Do not take KEFLOR DT 125MG TABLET if you are allergic to Cefaclor, other cephalosporin antibiotics, penicillin antibiotics or any of the other ingredients of this medicine.
Others
Before taking KEFLOR DT 125MG TABLET, inform your doctor if you:
- have history of gastrointestinal disease especially colitis (inflammation of colon)
Use in pediatrics:
Safety and efficacy of KEFLOR DT 125MG TABLET in infants (less than one month of age) have not been established. Consult your child’s doctor for advice.
Use in geriatrics:
No dosage changes of KEFLOR DT 125MG TABLET are necessary in elderly patients with normal kidney function. Consult your doctor before taking it.
Interactions
A. Drug - Drug interactions:
Before taking KEFLOR DT 125MG TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used as blood thinners to manage clotting of blood (Ex. warfarin, heparin)
- probenecid (used to manage gout)
Overdosage:
If you or anyone else accidentally take too much of KEFLOR DT 125MG TABLET, consult your doctor immediately or visit the nearby hospital. Signs and symptoms of overdose include nausea, vomiting, diarrhea and pain or discomfort in the upper abdomen.
Synopsis
| Drug | : | Cefaclor |
| Pharmacological Category | : | Cephalosporins |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet, Capsule, Syrup, Dry syrup, Suspension, Drops |
More Information
- Keep KEFLOR DT 125MG TABLET out of reach of children
- Store KEFLOR DT 125MG TABLET between 20-25°C
FAQs About KEFLOR DT 125MG TABLET
Can KEFLOR DT 125MG TABLET be given to infants?
Safety and efficacy of KEFLOR DT 125MG TABLET in infants (less than one month of age) have not been established so, consult your child’s doctor for advice. The doctor will determine the correct dose or select a suitable alternative management for your child.
Can KEFLOR DT 125MG TABLET be used to manage UTI?
Yes. KEFLOR DT 125MG TABLET is an antibiotic which effectively kills the bacteria that causes urinary tract infection (UTI) like cystitis by inactivating certain proteins which are necessary for the bacterial cell wall integrity and strength, thereby it damages the cell wall and kills the bacterial cell.
Can KEFLOR DT 125MG TABLET interfere with any blood tests?
Inform your doctor if you are having or are going to have any blood or urine tests as KEFLOR DT 125MG TABLET may interfere with these tests. Consult your doctor for further queries.
Can KEFLOR DT 125MG TABLET be used during pregnancy?
KEFLOR DT 125MG TABLET should be used in pregnancy only if your doctor finds it clearly necessary. If you are pregnant, think you may be pregnant or are planning to have a child, contact your doctor before taking it.
What should I do if I forget to take KEFLOR DT 125MG TABLET?
If you forget to take a dose of KEFLOR DT 125MG TABLET by chance, try to take it as soon as you notice. However, if the time for next dose is closer, skip the missed dose and do not double it.
Can I stop taking KEFLOR DT 125MG TABLET on my own?
Continue taking KEFLOR DT 125MG TABLET until your doctor tells you to stop, unless you experience any unwanted effects like an allergic reaction, diarrhoea, fits, worsening of your condition or any new symptoms. Contact your doctor in such situation.
References
1. KD. Tripathi. Beta-Lactam Antibiotics. Essentials of medical pharmacology. Eighth edition. 2019. Page –777.
2. PubChem Compound Summary for CID 51039, Cefaclor. National Center for Biotechnology Information. PubChem. November 2022. [Accessed on 24th November 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Cefaclor#:~:text=Cefaclor%20binds%20to%20and%20inactivates,cell%20wall%20strength%20and%20rigidity.
3. Hyo-In Rhyou, Go-Eun Doo, Jiwon Yoon, Chae-Yeon Ha, Hee-Joo Nam, Sung-Dae Woo, Youngsoo Lee, Young-Hee Nam and Young-Min Ye. Clinical characteristics and risk factors for cefaclor-induced immediate hypersensitivity: a retrospective observation at two university hospitals in Korea. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. February 2021. [Accessed on 24th November 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885353/
4. Douglas Pharmaceuticals Ltd. Cefaclor. [Revised in December 2018] [Accessed on 24th November 2022]. https://www.medsafe.govt.nz/profs/datasheet/r/RanbaxyCefaclorcapsusp.pdf
Useful Diagnostic Tests
- Complete blood count
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