New Revised MRP, 100% GST benefit passed Kabipem 100mg Injection 1's
Netmeds First Membership
Quick Links
Introduction About KABIPEM 100MG INJECTION
KABIPEM 100MG INJECTION contains Pemetrexed which belongs to the group of medicines called Anticancer agents. It is used to manage advanced stages of non-small cell lung cancer (NSCLC). It can be used as a management option to control cancer progression in patients who have failed to respond adequately to conventional therapies.
KABIPEM 100MG INJECTION is also used to manage malignant cancer of pleural membrane (a protective layer surrounding the lungs), called as pleural mesothelioma. It is mostly used in combination with other anti-cancer medicines (such as cisplatin, carboplatin) to achieve better results.
Before receiving KABIPEM 100MG INJECTION inform your doctor if you have any lung, liver, kidney or heart problems or a previous history of the same. You must also inform your doctor if you have fluid accumulation in the lungs or recently received or planning to receive any radiation therapy or vaccination in the upcoming days as a precaution.
KABIPEM 100MG INJECTION is not recommended for use in pregnant or breastfeeding women and in children aged below 18 years. Men and women receiving KABIPEM 100MG INJECTION must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with KABIPEM 100MG INJECTION and for until 6 months after stopping the therapy.
The most common side effects of receiving KABIPEM 100MG INJECTION are increased infections, sore throat, nausea, vomiting, stomach pain, dizziness, tiredness, weight loss, changes in taste, skin rash, hair loss and mouth ulcers. Contact your doctor if any of these side effect worsens.
Uses Of KABIPEM 100MG INJECTION
- Manage advanced non-small cell lung cancer (NSCLC)
- Manage malignant pleural mesothelioma (cancer of the protective layer of the lungs)
How KABIPEM 100MG INJECTION Works
KABIPEM 100MG INJECTION is an anticancer medication. It works by blocking the activity of certain enzymes (Ex. dihydrofolate reductase, thymidylate synthase etc.) in the body that may help cancer cells to grow and multiply. As a result, it reduces abnormal growth and multiplication of cancer cells in the body.
How to use KABIPEM 100MG INJECTION
KABIPEM 100MG INJECTION will be given to you only by a doctor or a nurse into a vein (as an intravenous infusion).
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Side Effects Of KABIPEM 100MG INJECTION
Common
- infections, fever, sore throat
- hair loss
- nausea, vomiting, loss of appetite
- stomach pain, indigestion, constipation, diarrhea
- mouth ulcers (pain, redness, swelling on the mouth)
- tiredness, dehydration, dizziness
- skin rash (marks may resemble bull’s eye)
- flaky skin, loss of sensation on the skin, increased skin pigmentation
- changes in taste
- muscle weakness or wasting, unsteady movements
- eye inflammation, dry eyes, eye swelling, eye irritation, tearing
- irregular heartbeat
- increase in liver and kidney enzymes
- swelling of body parts
- inflammation of the gut
Uncommon
- rectal inflammation or bleeding
- inflammation and redness of esophagus
Rare
Contact your doctor immediately if you experience any of the following side effects after receiving KABIPEM 100MG INJECTION:
- fever, increased infections, sepsis (infections of the blood)
- chest pain, fast heart rate
- inflammation of the mouth with pain, redness and swelling
- signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth, or throat which can lead to difficulty in breathing or swallowing)
- severe skin reactions with blistering and peeling of skin, burning or prickling sensation or fever
- signs of low RBC in blood (tiredness, pale skin, fainting, breathlessness)
- increased tendency to bleed (such as bleeding gums, bleeding from the nose or mouth)
- unexpected bruising
- signs of blood clot in lungs (such as breathlessness, heavy chest pain or cough with bloody sputum)
How To Manage Side Effects
Skin rash:
Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash worsens.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Consult your doctor if your headache worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Consult your doctor if your dizziness worsens.
Nausea and Vomiting:
Stick to simple meals. Avoid eating oil rich or spicy foods. If your nausea worsens, consult your doctor for advice
Mouth ulcers:
Avoid eating spicy foods. Drink plenty of water. Apply a pain-relieving gel on the affected areas of the mouth if required. Consult your doctor if the symptom did not improve
Diarrhoea
Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to manage diarrhoea and consult your doctor if the symptom gets worse.
Constipation
Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate managements for constipation.
Warning & Precautions
Pregnancy
KABIPEM 100MG INJECTION is generally not recommended for use in pregnant women due to increased risk of side effects. Women of childbearing potential must use a suitable contraceptive to avoid pregnancy while undergoing therapy with KABIPEM 100MG INJECTION. If you accidentally became pregnant while receiving KABIPEM 100MG INJECTION, inform your doctor immediately.
Breastfeeding
KABIPEM 100MG INJECTION is generally not recommended for use in breastfeeding women as it may pass through breast milk. Therefore, consult your doctor before receiving it.
Driving and Using Machines
Do not drive or operate any machines if you feel tired after receiving KABIPEM 100MG INJECTION.
Kidney
KABIPEM 100MG INJECTION should be used with caution in patients with kidney problems. It should also be used with caution in patients who has a previous history of kidney problems. Therefore, consult your doctor before receiving it.
Liver
KABIPEM 100MG INJECTION should be used with caution in patients with liver problems. Therefore, consult your doctor before receiving it.
Allergy
Do not receive KABIPEM 100MG INJECTION if you are allergic to pemetrexed or to any of the other ingredients of the medicines.
Lungs
KABIPEM 100MG INJECTION should be used with caution in patients with fluid accumulation around the lungs. Therefore, consult your doctor before receiving it.
Heart Disease
KABIPEM 100MG INJECTION should be used with caution in patients with heart problems. It should also be used with caution in patients who has a previous history of heart problems. Therefore, consult your doctor before receiving it.
Others
Before receiving KABIPEM 100MG INJECTION inform your doctor if you:
- have had or are going to take radiation therapy
- have been recently vaccinated
Use in pediatrics:
KABIPEM 100MG INJECTION is generally not recommended for use in children and adolescents (under 18 years of age) due to lack of safety data. Therefore, consult your doctor before receiving it.
Use in geriatrics:
KABIPEM 100MG INJECTION should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before receiving it.
Interactions
A. Drug-Drug interactions:
Before receiving KABIPEM 100MG INJECTION inform your doctor if you are taking any of the following medicine:
- medicines used to manage pain and inflammation (Ex. ibuprofen)
- live or attenuated vaccines (Ex. yellow fever vaccine)
Overdosage:
KABIPEM 100MG INJECTION will be administered to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your physician or nurse if you experience any unusual symptoms.
Synopsis
| Drug | : | Pemetrexed |
| Pharmacological Category | : | Folate Antagonists |
| Therapeutic Indication | : | Advanced non-small cell lung cancer |
| Dosage Forms | : | Injection |
More Information
- Keep KABIPEM 100MG INJECTION out of reach of children
- Store KABIPEM 100MG INJECTION at room temperature
FAQs About KABIPEM 100MG INJECTION
What KABIPEM 100MG INJECTION is used for?
KABIPEM 100MG INJECTION is used to manage advanced non-small cell lung cancer. It can also be used to manage metastatic cancer of pleural membrane (a protective layer surrounding the lungs), called as pleural mesothelioma
How KABIPEM 100MG INJECTION works on my body?
KABIPEM 100MG INJECTION is an anticancer medication. It works by blocking the activity of certain enzymes (Ex. dihydrofolate reductase, thymidylate synthase etc.) in the body that may help cancer cells to grow and multiply. As a result, it reduces abnormal growth and multiplication of cancer cells in the body.
Can KABIPEM 100MG INJECTION manage cancer?
The manage rate of cancer depends upon the severity of the disease. However, KABIPEM 100MG INJECTION acts by managing the abnormal growth and multiplication of cancer cells in the body, which may help in managing cancer completely.
Can the use of KABIPEM 100MG INJECTION cause hair loss?
Hair loss is one of the common side effects of receiving KABIPEM 100MG INJECTION. If it bothers you, consult your doctor for advice.
Can the use of KABIPEM 100MG INJECTION cause mouth ulcers?
Mouth ulcers are one of the common side effects of receiving KABIPEM 100MG INJECTION. Avoid eating spicy foods. Drink plenty of water. Apply a pain-relieving gel on the affected areas of the mouth if required. Consult your doctor if the symptom did not improve
Can KABIPEM 100MG INJECTION be used in children?
KABIPEM 100MG INJECTION should not be used in children aged below 18 years. Therefore, consult your doctor before receiving it.
Is KABIPEM 100MG INJECTION a chemo drug?
Yes. KABIPEM 100MG INJECTION contains a medicine called pemetrexed which is a chemotherapeutic agent. It stops abnormal growth and multiplication of cancer cells in the body.
What precautions must be followed while taking KABIPEM 100MG INJECTION?
Before taking KABIPEM 100MG INJECTION inform your doctor if you have any lung, liver, kidney or heart problems. You must also inform your doctor if you have fluid accumulation in the lungs or recently received or planning to receive any radiation therapy or vaccination in the upcoming days as a precaution. Inform your doctor before receiving KABIPEM 100MG INJECTION if you are a pregnant or a breastfeeding woman. Men and women receiving KABIPEM 100MG INJECTION must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with KABIPEM 100MG INJECTION.
What happens if I stop receiving KABIPEM 100MG INJECTION?
No. Do not stop receiving KABIPEM 100MG INJECTION without consulting your doctor as it may make your symptoms reappear. Therefore, take KABIPEM 100MG INJECTION as advised by your doctor for the stipulated duration.
Can KABIPEM 100MG INJECTION be used during pregnancy?
KABIPEM 100MG INJECTION is generally not recommended for use in pregnant women. If you accidentally became pregnant while receiving KABIPEM 100MG INJECTION, inform your doctor immediately.
Can the use of KABIPEM 100MG INJECTION make me feel tired?
Yes. KABIPEM 100MG INJECTION may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anemic. Consult your doctor if you experience tiredness after receiving KABIPEM 100MG INJECTION. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while taking this medicine.
Can I drive a car after receiving KABIPEM 100MG INJECTION?
KABIPEM 100MG INJECTION may make you feel tired or dizzy. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by KABIPEM 100MG INJECTION.
How KABIPEM 100MG INJECTION is administered?
KABIPEM 100MG INJECTION will be given to you only by a doctor or a nurse into a vein (as an intravenous infusion).
How to control nausea caused due to KABIPEM 100MG INJECTION?
Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with KABIPEM 100MG INJECTION. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-manage nausea.
What are the side effects of receiving KABIPEM 100MG INJECTION?
The most common side effects of receiving KABIPEM 100MG INJECTION are increased infections, sore throat, nausea, vomiting, stomach pain, dizziness, tiredness, weight loss, changes in taste, skin rash, hair loss and mouth ulcers. Contact your doctor if any of these side effect worsens.
Who should avoid taking KABIPEM 100MG INJECTION?
KABIPEM 100MG INJECTION is not recommended for use if you are allergic to pemetrexed. It is also not recommended for use in pregnant or breastfeeding women and in children (aged below 18 years).
Is KABIPEM 100MG INJECTION safe to use in kidney disease?
KABIPEM 100MG INJECTION should be used with caution in patients with kidney problems. Your doctor will access your health condition and suggest a suitable dose for you.
Can the use of KABIPEM 100MG INJECTION affect the liver?
Yes. KABIPEM 100MG INJECTION may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before taking it.
References
1. KD. Tripathi. Anti-cancer Drugs. Essential of Medical Pharmacology. 7th Edition. 2013. Page – 863.
2. K. Al-Saleh, MBBS MSc, C. Quinton, MD and P.M. Ellis, MD PhD. Role of pemetrexed in advanced non-small-cell lung cancer: meta-analysis of randomized controlled trials, with histology subgroup analysis. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. February 2015. [Accessed on 15th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267597/
3. Seacross Pharmaceuticals Ltd. Medicines Compendium (EMC). [Revised in March 2021]. [Accessed on 15th November 2022] https://www.medicines.org.uk/emc/files/pil.8887.pdf
4. Central Drugs Standard Control Organization. Pemetrexed Injection. [Accessed on 15th November 2022] https://cdscoonline.gov.in/CDSCO/Drugs
Author Details
