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Introduction About JOSPAN 40 TABLET
JOSPAN 40 TABLET is used to manage peptic ulcers, gastroesophageal reflux disease (GERD) and reflux esophagitis and its associated symptoms such as acidity, heartburn, acid reflux and pain in swallowing. It contains Pantoprazole which belongs to the group of medicines called Proton pump inhibitors. JOSPAN 40 TABLET can also be used to manage peptic ulcer caused due to long-term use of non-steroidal anti-inflammatory drugs (such as aspirin, ibuprofen).
Take JOSPAN 40 TABLET at least 1 hour before meals to achieve maximum benefits. During management with JOSPAN 40 TABLET your doctor will closely monitor kidney functions, liver functions and blood magnesium levels to avoid the risk of unwanted side effects. Before taking inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have weak bones or any previous history of bleeding in the gut.
Consult your doctor before taking JOSPAN 40 TABLET if you are pregnant or breastfeeding. The most common side effects are dryness of mouth, constipation and flatulence. You must also inform your doctor immediately if you experience severe tiredness with abnormal muscle movements, dizziness, confusion, disorientation and irregular heartbeat, as it could be a sign of low magnesium levels in blood.
Uses Of JOSPAN 40 TABLET
It is used to manage:
- Peptic ulcer and manages its recurrence
- Gastrointestinal Reflux disease (GERD)
- Reflux esophagitis (inflammation of the esophagus)
- Acidity, Heartburn, Pain in swallowing
How JOSPAN 40 TABLET Works
JOSPAN 40 TABLET contains Pantoprazole which helps to reduce gastric acid secretion by the blocking the actions of a protein membrane called H+K+Atpase (proton pump) across the stomach lining. As a result, it manages the worsening of ulcers, heals the existing ulcers and esophageal lesions and provides relief from the unpleasant symptoms of GI tract (such as acidity, heartburn and acid reflux).
How to use JOSPAN 40 TABLET
- Take JOSPAN 40 TABLET 30 minutes to 1 hour before meals or as advised by your physician
- Swallow the medicine with a glass of water. Do not crush or chew the medicine
- Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
- Do not stop taking JOSPAN 40 TABLET unless your doctor advice you to stop
Side Effects Of JOSPAN 40 TABLET
Common side effects of JOSPAN 40 TABLET:
- benign polyps in the stomach
- headache
- dizziness, drowsiness
- feeling weak
- nausea or vomiting
- diarrhea, constipation, stomach pain, flatulence
- dry mouth
Stop taking JOSPAN 40 TABLET and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions (such as skin rash, itching, swelling of the lips, face or body and difficulty in breathing or swallowing)
- signs of liver problems (yellowing of the skin and eyes, dark urine and tiredness)
- severe skin reactions (such as redness, blistering, peeling of skin and bleeding in the lips, eyes, mouth, nose and genitals with fever)
- signs of kidney problem (such as lower back pain, painful urination)
- signs of low magnesium levels in blood (such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat)
- sudden weight loss, looking pale and weak (anemia)
- signs of bleeding in the gut (such as bloody vomits/stools)
- uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture
Warning & Precautions
Pregnancy
Monitoring requiredJOSPAN 40 TABLET should be used in pregnant women only if it is considered necessary by the physician.
Breastfeeding
Monitoring requiredJOSPAN 40 TABLET may pass through breast milk. Therefore, it should be used in breastfeeding women only if it is considered necessary by the physician.
Driving and Using Machines
Use with CautionJOSPAN 40 TABLET does not affect your ability in driving or handling heavy tools or machines.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking JOSPAN 40 TABLET, as it could aggravate your existing condition.
Kidney
Use with CautionJOSPAN 40 TABLET should be used with caution in patients with kidney problems.
Liver
Use with CautionJOSPAN 40 TABLET should be used with caution in patients with liver problems.
Allergy
ContraindicatedDo not take JOSPAN 40 TABLET if you are allergic to Pantoprazole or any other ingredients of this medicine.
Use In Pediatrics
ContraindicatedJOSPAN 40 TABLET is not recommended for use in children and adolescents as it has not been proven to work in children below 12 years of age.
Use In Geriatrics
Use with CautionJOSPAN 40 TABLET should be used with caution in elderly patients (aged 65 years and above).
Others
Before taking JOSPAN 40 TABLET, inform your doctor if you:
- have osteoporosis
- have a history of bleeding in the gut
- have vitamin B12 deficiency (sore tongue, mouth ulcers, pale skin)
- are going to test Chromogranin A level
Interactions
A. Drug-Drug interactions:
Before taking JOSPAN 40 TABLET inform your doctor if you are taking any of the following medicines such as:
- Antifungal (Ex. ketoconazole, itraconazole and Posaconazole)
- Anti-cancer agents (Ex. erlotinib)
- Anticoagulants (Ex. warfarin and phenprocoumon)
- Antimetabolites (Ex. methotrexate)
- Anti-viral agents (Ex. atazanavir)
- Antidepressants (Ex. fluvoxamine)
- Antibiotics (Ex. rifampicin)
- Herbal medicine (Ex. St. John’s wort)
Overdosage:
If you or anyone else accidentally took more JOSPAN 40 TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Pantoprazole |
| Pharmacological Category | : | Proton pump inhibitors |
| Therapeutic Indication | : | Peptic ulcer, GERD, Reflux esophagitis |
| Dosage Forms | : | Tablet, Capsule, Injection, Infusion, Prefilled Syringe, Kit |
FAQs About JOSPAN 40 TABLET
Q: What is JOSPAN 40 TABLET used for?
A: JOSPAN 40 TABLET is used to manage peptic ulcers, gastroesophageal reflux disease (GERD) and reflux esophagitis and its associated symptoms such as acidity, heartburn, acid reflux and pain in swallowing.
Q: How and when to take JOSPAN 40 TABLET?
A: Take JOSPAN 40 TABLET at least 1 hour before meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Q: How long should I take JOSPAN 40 TABLET?
A: You need to take JOSPAN 40 TABLET for the stipulated duration prescribed by your doctor. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: What is the best time to take JOSPAN 40 TABLET?
A: JOSPAN 40 TABLET must be taken before meals to avoid gastrointestinal side effects.
Q: What to do if I forgot to take a dose of JOSPAN 40 TABLET?
A: If you forgot to take a dose of JOSPAN 40 TABLET, take it as soon as you remember. However, if it is time for the next dose, skip the missed dose and take the next one regularly.
Q: What are the most common side effects of taking JOSPAN 40 TABLET?
A: The most common side effects of taking JOSPAN 40 TABLET are dryness of mouth, constipation and flatulence. Consult your doctor if any of these side effect bothers you.
Q: Can I stop taking JOSPAN 40 TABLET without consulting your doctor?
A: No. You should not stop taking JOSPAN 40 TABLET without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using JOSPAN 40 TABLET, consult your doctor for advice.
Q: Will taking a higher dose of JOSPAN 40 TABLET be more effective?
A: No, taking a higher dose of JOSPAN 40 TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Q: What precautions do I need to follow while taking JOSPAN 40 TABLET?
A: Make sure to take JOSPAN 40 TABLET 30 minutes to 1 hour before meals. Before taking JOSPAN 40 TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have weak bones or a previous history of bleeding in the gut. Regularly visit your doctor and take all the blood tests recommended by your doctor without fail.
Q: Can I take medication for high blood pressure along with JOSPAN 40 TABLET?
A: It is not advisable to take medicines to control blood pressure while taking JOSPAN 40 TABLET without consulting your doctor as they have known interactions with the medicine.
Q: Can JOSPAN 40 TABLET be used in pregnant women?
A: JOSPAN 40 TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.
Q: Can JOSPAN 40 TABLET cause constipation?
A: Yes. Constipation is a common side effect of taking JOSPAN 40 TABLET. Eat plenty of fiber rich foods such as fresh fruits, vegetables, cereals as well as drink plenty of water and exercise more regularly when taking this medicine. Contact your doctor if this side effect bothers you.
References
1. KD Tripathi. Drugs for Peptic Ulcer and Gastroesophageal Reflux Disease. Essentials of medical pharmacology. Eighth Edition. 2019. Page –701.
2. Andrzej Dabrowski, Borut Štabuc and Leonid Lazebnik. Meta-analysis of the efficacy and safety of pantoprazole in the treatment and symptom relief of patients with gastroesophageal reflux disease. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. March 2018. [Accessed on 22nd October 2022] click here
3. Balkanpharma – Dupnitsa AD. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed on 22nd October 2022] click here
4. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in November 2021] [Accessed on 22nd October 2022] click here
5. Central Drugs Standard Control Organization. Pantoprazole Tablets. [Revised in December 1998] [Accessed on 22nd October 2022] click here
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