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INTRODUCTION ABOUT HYDROEYES
HYDROEYES contains Cyclosporin which belongs to the group of medicines called Immunosuppressants. It is used to manage severe dry eye syndrome (keratoconjunctivitis sicca) in children and in adolescents (aged between 4-18 years).
Dry Eye Syndrome (also known as keratoconjunctivitis sicca) is an allergic eye condition that affects the transparent layer in the front part of the eye and the thin membrane covering the front part of the eye. It is characterized by excessive eye dryness, redness, itching, inflammation and discomfort. Persons having dry eye syndrome do not produce sufficient tears to lubricate and nourish the eyes.
HYDROEYES is for ophthalmic use only. Wash your hands before and after application. Avoid touching the tip of the container with your mouth, nose or other parts of body to avoid contamination.
If you wear soft contact lenses, make sure to remove them before using HYDROEYES. Consult your doctor about the usage of contact lenses while undergoing management for dry eyes.
Before using HYDROEYES inform your doctor if you have any other eye conditions apart from dry eye syndrome such as eye infection or glaucoma. HYDROEYES is not recommended for use in patients having cancer in and around the eye areas. Consult your doctor before using HYDROEYES if you are pregnant or breastfeeding.
The most common side effects of using HYDROEYES are eye pain, redness, irritation or discomfort, watery eyes and blurred vision. Consult your doctor if they trouble you.
USES OF HYDROEYES
- Manage severe dry eye syndrome
HOW HYDROEYES WORKS
HYDROEYES is an immunosuppressive agent. Following application on the eyes, it blocks the release of certain chemicals in the eye (such as T-cells, interleukins and cytokines) that causes eye inflammation, allergies and discomfort. As a result, it reduces inflammation and swelling on the eye and keeps your eyes lubricated by allowing your eye to produce tears.
DIRECTIONS FOR USE
Use HYDROEYES as advised by your physician. It is for ophthalmic use only. Wash your hands before application. Tilt your head slightly backwards and place the tip of the container close to your eyes.
Gently pull your lower eyelid and instil few drops of the medicine as directed by your physician. Close your eyes and gently press the inner corner of your eye for 2 minutes. Repeat the same for the other eye if required.
Do not touch the tip of the container with your eyes, eyelids or areas around your eyes or fingers, to avoid contamination. Avoid wearing contact lenses while undergoing therapy for dry eyes.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop using HYDROEYES unless your doctor tells you to stop.
SIDE EFFECTS OF HYDROEYES
COMMON
- Eye pain, redness, irritation or discomfort
- Sensation of foreign body in the eye
- Increased watering of eyes
- Blurred vision
- Swelling and redness of eyelids
- Upper respiratory tract
- Cough, headache
HOW TO MANAGE SIDE EFFECTS
Eye irritation, redness or discomfort:
Avoid watching direct light sources. Do not strain your eyes too much. Protect your eyes from bright light while going outdoors using sunglasses. Consult your doctor if this side effect bothers you.
Blurred vision:
Close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
WARNING & PRECAUTIONS

PREGNANCY
HYDROEYES is not recommended for use in pregnant women. Therefore, consult your doctor before using it. Women of childbearing potential should use suitable contraceptive to manage pregnancy while undergoing therapy with HYDROEYES.

BREASTFEEDING
HYDROEYES should be used with caution in breast-feeding women. Therefore, consult your doctor before using it.

DRIVING AND USING MACHINES
HYDROEYES may temporarily blur your vision. Therefore, do not drive or handle any heavy tools or machines if you experience blurred vision after applying HYDROEYES.

ALCOHOL
Consumption of alcohol is not recommended during management with HYDROEYES.

ALLERGY
Do not use HYDROEYES if you are allergic to cyclosporin.
OTHERS
HYDROEYES is not recommended for use if you:
- have or ever had cancer in or around eyes
- have an eye infection
Before using HYDROEYES inform your doctor if you:
- had an eye infection (herpes viral infection) or suspect of having it
- have any other eye problems (such as glaucoma)
Use in paediatrics:
HYDROEYES is not recommended for use in children (aged below 4 years). Therefore, consult your doctor before using it.
INTERACTIONS
A. Drug - Drug interactions:
Before using HYDROEYES, inform your doctor if you are taking any of the following medicine:
- eye drops containing steroids (Ex. dexamethasone)
- medicines used to manage glaucoma (Ex. latanoprost, travoprost, tafluprost, bimatoprost)
Overdosage:
If you or anyone else accidentally used excessive amount of HYDROEYES, rinse your eyes with plain water to ease the irritation. If you irritation persists, consult your doctor.
SYNOPSIS
Drug | : | Cyclosporin |
Pharmacological Category | : | Calcineurin Inhibitors |
Therapeutic Indication | : | Dry Eye Syndrome |
Dosage Forms | : | Tablet, capsule, Injection, Infusion, Oral Solution, Oral Suspension, Eye Drops, Ophthalmic Emulsion |
MORE INFORMATION
- Keep HYDROEYES out of reach of children
- Store HYDROEYES at room temperature
FAQs ABOUT HYDROEYES
What is the use of HYDROEYES?
HYDROEYES is used to manage severe dry eye syndrome (keratoconjunctivitis sicca) in children and in adolescents (aged between 4-18 years).
How HYDROEYES works?
HYDROEYES is an immunosuppressive agent. Following application on the eyes, it blocks the release of certain chemicals in the eye (such as T-cells, interleukins and cytokines) that causes eye inflammation, allergies and discomfort. As a result, it reduces inflammation and swelling on the eye and keeps your eyes lubricated by allowing your eye to produce tears.
How to take HYDROEYES?
Wash your hands before application. Tilt your head slightly backwards and place the tip of the container close to your eyes. Gently pull your lower eyelid and instil few drops of the medicine as directed by your physician. Close your eyes and gently press the inner corner of your eye for 2 minutes. Repeat the same for the other eye if required.
How long should I use HYDROEYES?
You need to use HYDROEYES for the stipulated duration prescribed by your doctor. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Is HYDROEYES safe?
HYDROEYES is safe at doses prescribed by the physician. Therefore, do not alter the dose of HYDROEYES without consulting your doctor.
Can I stop using HYDROEYES without consulting your doctor?
No. You should not stop using HYDROEYES without consulting your doctor as it may cause the symptoms to re-appear. Therefore, use HYDROEYES for the stipulated duration recommended by your doctor to achieve maximum results.
Will using a higher dose of HYDROEYES be more effective?
No, using a higher dose of HYDROEYES will not be effective rather it can lead to toxicity. Always apply the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Can HYDROEYES be used in pregnant women?
HYDROEYES is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before using it.
What are the common side effects of using HYDROEYES?
The most common side effects of using HYDROEYES are eye pain, redness, irritation or discomfort, watery eyes and blurred vision. Consult your doctor if they trouble you.
What to do if I forgot to apply HYDROEYES?
If you forgot to apply a dose of HYDROEYES, apply it as soon as you remember. However, if it is time for the next dose of HYDROEYES, skip the missed dose and apply the next one regularly. Do not apply a double dose of HYDROEYES to compensate the missed ones.
How long will it take for HYDROEYES to heal my condition?
You need to apply HYDROEYES as long as your doctor prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Can I use other eye medicines while using HYDROEYES?
Avoid using any other eye medicines along with HYDROEYES without consulting your doctor as it may increase the risk of side effects.
Can HYDROEYES reduce conjunctivitis?
Yes. HYDROEYES can be used to manage allergic eye conditions (such as allergic conjunctivitis, keratoconjunctivitis, etc.).
Can the use of HYDROEYES cause blurred vision?
Yes. HYDROEYES may cause blurred vision after application. If your vision becomes blur, close your eyes for some time and rest. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
REFERENCES
1. KD. Tripathi. Immunosuppressant Drugs. Essentials of Medical pharmacology. 7th Edition. 2013. Page – 878.
2. Philip Ames and Anat Galor. Cyclosporine ophthalmic emulsions for the treatment of dry eye: a review of the clinical evidence. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on 22nd November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420022/
3. Clyde Schultz. Safety and Efficacy of Cyclosporine in the Treatment of Chronic Dry Eye. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. June 2014. [Accessed on 22nd November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076204/
4. Santen Oy. Electronic Medicines Compendium (EMC) [Revised in January 2022] [Accessed on 22nd November 2022] https://www.medicines.org.uk/emc/files/pil.9491.pdf
5. Central Drugs Standard Control Organization. Cyclosporin 0.05% eye drops. March 2003. Cyclosporin Eye drops (0.1%). June 2006. [Accessed on 22nd November 2022] https://cdscoonline.gov.in/CDSCO/Drugs