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Cipla Ltd

Hydrazide 50mg Tablet 200'S

Hypertension
MRP ₹16.96 (Inclusive of all taxes)
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    Introduction About HYDRAZIDE 50MG TABLET

    HYDRAZIDE 50MG TABLET contains Hydrochlorothiazide which belongs to the group of medicines called Diuretics. It is as an adjuvant therapy in managing edema (fluid accumulation) that is caused due to heart failure, liver inflammation (Ex. liver cirrhosis), kidney problems or due to intake of steroid medications. It can also be used in the management of hypertension (high blood pressure) either alone or in combination with other medications.

    During management with HYDRAZIDE 50MG TABLET your doctor will constantly monitor your kidney functions, blood pressure, electrolyte levels and blood sugar levels to avoid the risk of unwanted side effects.

    Before taking HYDRAZIDE 50MG TABLET inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have diabetes, asthma, diabetes, low blood potassium levels, gout or electrolyte imbalance as a precaution.

    Consult your doctor before taking HYDRAZIDE 50MG TABLET if you are pregnant or breastfeeding. The most common side effects of taking HYDRAZIDE 50MG TABLET are headache, dizziness, stomach pain, constipation, muscle spasm, blurred vision and impotence. Contact your doctor if any of these side effect worsens.

    Uses Of HYDRAZIDE 50MG TABLET

    • Manage oedema (fluid accumulation in the body parts which causes swelling)
    • Manage hypertension (high blood pressure)

    How HYDRAZIDE 50MG TABLET Works

    HYDRAZIDE 50MG TABLET is a diuretic. It acts by removing excess water from the body in the form of urine. This reduces swelling of body parts and manages fluid accumulation. It also reduces the thickness of blood which reduces the strain on the heart and helps the heart to pump blood more smoothly with less pressure.

    How to use HYDRAZIDE 50MG TABLET

    Take HYDRAZIDE 50MG TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Try to take HYDRAZIDE 50MG TABLET at the same time each day.

    Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Continue to take HYDRAZIDE 50MG TABLET for the stipulated duration instructed by your doctor without any interruption to achieve better results.

    Side Effects Of HYDRAZIDE 50MG TABLET

    Common

    • weakness
    • feeling dizzy while standing up
    • nausea or vomiting
    • stomach pain, diarrhea, constipation, indigestion
    • changes in blood count
    • skin sensitivity towards light
    • skin rash, itching
    • muscle spasm
    • spinning sensation, dizziness, headache
    • tingling and numbness of body parts
    • blurred vision, colour blindness
    • impotence, low sex drive

    Rare

    Stop taking HYDRAZIDE 50MG TABLET and contact your doctor immediately if you experience any of the following side effects:

    • signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth or throat which can lead to difficulty in breathing or swallowing)
    • severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane)
    • severe kidney problems
    • glaucoma or vision problems

    How To Manage Side Effects

    Constipation

    Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.

    Dizziness Or Drowsiness

    Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

    Headache

    Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

    Nausea And Vomiting

    Take HYDRAZIDE 50MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.

    Warning & Precautions

    Pregnancy

    Monitoring required

    HYDRAZIDE 50MG TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.

    Breastfeeding

    Use with Caution

    HYDRAZIDE 50MG TABLET may pass through breast milk. Therefore, it should be used with caution in breastfeeding women. Consult your doctor for advice before taking it.

    Driving and Using Machines

    Use with Caution

    Do not drive or handle any heavy tools or machines if you experience dizziness or drowsiness after taking HYDRAZIDE 50MG TABLET.

    Alcohol

    Consult your doctor

    Avoid consumption of alcohol while taking HYDRAZIDE 50MG TABLET as it might make you feel dizzier and drowsier.

    Kidney

    Use with Caution

    HYDRAZIDE 50MG TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.

    Liver

    Use with Caution

    HYDRAZIDE 50MG TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.

    Allergy

    Contraindicated

    Do not take HYDRAZIDE 50MG TABLET if you are allergic to Amlodipine or Hydrochlorothiazide.

    Lungs

    Use with Caution

    HYDRAZIDE 50MG TABLET should be used with caution in patients with asthma or any breathing problems. Therefore, consult your doctor before taking it.

    Use In Pediatrics

    Consult your doctor

    There is no proper information regarding the use of HYDRAZIDE 50MG TABLET in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice before taking it.

    Use In Geriatrics

    Use with Caution

    HYDRAZIDE 50MG TABLET should be used with caution in the elderly patients. Therefore, consult your doctor before taking it.

    Others

    HYDRAZIDE 50MG TABLET is not recommended for use if you:

    • do not pass urine (anuria)

    Before taking HYDRAZIDE 50MG TABLET, inform your doctor if you:

    • have a history of allergy
    • have diabetes
    • have hypokalaemia (low blood potassium levels)
    • have gout (painful joints)
    • have low sodium, potassium, or magnesium levels in the blood
    • are scheduled for testing parathyroid functions

    Interactions

    A. Drug - Drug interactions:

    Before taking HYDRAZIDE 50MG TABLET, inform your doctor if you are taking any of the following medicines such as:

    • other medicines used to manage high blood pressure or angina (Ex. diltiazem, verapamil)
    • medicines that can depress the brain such as barbiturates (Ex. phenobarbital)
    • narcotic drugs (used for pain relief) such as morphine, fentanyl, pethidine
    • medicines used to manage diabetes (such as insulin, metformin, glimepiride)
    • medicines used to reduce blood cholesterol levels (such as cholestyramine, colestipol)
    • corticosteroids (used to manage inflammation) Ex. prednisolone
    • noradrenaline (a medicine used to increase blood pressure)
    • tubocurarine, dantrolene (medicines used to relax muscles)
    • medicines used for pain and inflammation (such as ibuprofen or indomethacin)
    • lithium (a medicine used to manage metal illnesses)

    Overdosage:

    If you or anyone else accidentally took more HYDRAZIDE 50MG TABLET, consult your doctor immediately. Overdosage may cause electrolyte imbalance and dehydration.

    Synopsis

    Drug :   Hydrochlorothiazide
    Pharmacological Category :   Thiazide diuretics
    Therapeutic Indication :   Oedema, Hypertension
    Dosage Forms :   Tablet

    More Information

    • Keep HYDRAZIDE 50MG TABLET out of reach of children
    • Store HYDRAZIDE 50MG TABLET at room temperature

    FAQs About HYDRAZIDE 50MG TABLET

    Q: What are the uses of HYDRAZIDE 50MG TABLET?

    A: HYDRAZIDE 50MG TABLET is prescription medicine used to manage oedema and hypertension.

    Q: What type of a medicine is HYDRAZIDE 50MG TABLET?

    A: HYDRAZIDE 50MG TABLET is a diuretic. It acts by removing excess water from the body in the form of urine. This reduces swelling of body parts and manages fluid accumulation. It also reduces the thickness of blood which reduces the strain on the heart and helps the heart to pump blood more smoothly with less pressure.

    Q: What happens when I stop taking HYDRAZIDE 50MG TABLET?

    A: Do not stop taking HYDRAZIDE 50MG TABLET without consulting your doctor as your symptoms may re-appear once again. Make sure to take HYDRAZIDE 50MG TABLET for the stipulated duration recommended by your doctor to achieve maximum results.

    Q: What is the best time to take HYDRAZIDE 50MG TABLET?

    A: HYDRAZIDE 50MG TABLET can be taken with or without meals. Your doctor will decide the best time for you to take HYDRAZIDE 50MG TABLET based on your age, body weight and disease condition.

    Q: What to do if I forgot to take a dose of HYDRAZIDE 50MG TABLET?

    A: If you forgot to take a dose of HYDRAZIDE 50MG TABLET, take it as soon as you remember. However, if it is time for the next dose of HYDRAZIDE 50MG TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of HYDRAZIDE 50MG TABLET to compensate the missed ones.

    Q: What precautions should be followed while taking HYDRAZIDE 50MG TABLET?

    A: Before taking HYDRAZIDE 50MG TABLET, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have diabetes, asthma, dehydration, gout or electrolyte imbalance. Consult your doctor before taking HYDRAZIDE 50MG TABLET if you are pregnant or breastfeeding. Regularly visit your doctor and take all the necessary blood test recommended by your doctor without fail.

    Q: Can I consume alcohol while taking HYDRAZIDE 50MG TABLET?

    A: Avoid consumption of alcohol while taking HYDRAZIDE 50MG TABLET as it might make you feel dizzier and drowsier.

    Q: What happens if I accidentally take more HYDRAZIDE 50MG TABLET?

    A: If you or anyone else accidentally took more HYDRAZIDE 50MG TABLET, consult your doctor immediately. Overdosage may cause severe dehydration.

    Q: Can I take HYDRAZIDE 50MG TABLET daily?

    A: Take HYDRAZIDE 50MG TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take HYDRAZIDE 50MG TABLET every day or not.

    Q: Is HYDRAZIDE 50MG TABLET safe to use in diabetic patients?

    A: HYDRAZIDE 50MG TABLET may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before taking HYDRAZIDE 50MG TABLET as a precaution. Your doctor will closely monitor you blood sugar levels to avoid the risk of side effects.

    Q: What are the side effects of HYDRAZIDE 50MG TABLET?

    A: The most common side effects of taking HYDRAZIDE 50MG TABLET are headache, dizziness, stomach pain, constipation, muscle spasm, blurred vision and impotence. Contact your doctor if any of these side effect worsens.

    Q: Can I stop taking HYDRAZIDE 50MG TABLET once my symptoms subside?

    A: No. Do not stop taking HYDRAZIDE 50MG TABLET without consulting your doctor. As hypertension is a chronic condition, long term management may be necessary to control its symptoms. Therefore, take HYDRAZIDE 50MG TABLET as advised by your doctor for the stipulated duration. Premature discontinuation of therapy may increase your blood pressure once again.

    Q: Can HYDRAZIDE 50MG TABLET be taken during pregnancy?

    A: HYDRAZIDE 50MG TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.

    Q: Is HYDRAZIDE 50MG TABLET safe to use in kidney disease?

    A: HYDRAZIDE 50MG TABLET should be used with caution in patients with kidney problems (such as kidney transplant, narrowing of renal arteries). Your doctor will access your health condition and suggest a suitable dose for you.

    Q: Can the use of HYDRAZIDE 50MG TABLET affect the liver?

    A: Yes. HYDRAZIDE 50MG TABLET may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before taking it.

    References

    1. KD. Tripathi. Antihypertensive Drugs. Diuretics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 559 & 582.

    2. Linda L. Herman; Khalid Bashir. Hydrochlorothiazide. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. July 2022. [Accessed on 11th February 2023].

    3. Mylan Pharmaceuticals Inc. U.S. Food and Drug Administration. [Revised in May 2011] [Accessed on 11th February 2023]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/040735s004,040770s003lbl.pdf

    Useful Diagnostic Tests

    • Kidney Function Test

    Author Details

    Written By Srilekha. R - B.Pharm
    Reviewed For Accuracy By Dr. Venkatesh Poludasu - MBBS
    Last updated on 14 Feb 2023 | 07:08 PM(IST)
    Lab updated