Homochek Capsule 10'S

Introduction About HOMOCHEK CAPSULE

Homochek Capsule is a vitamin-rich nutritional supplement designed to help meet the daily requirements of essential B-complex vitamins like methylcobalamin (Vitamin B12), folic acid (Vitamin B9) and pyridoxine (Vitamin B6). These nutrients play a key role in maintaining healthy nerve function, supporting red blood cell formation, and improving overall energy levels. Homochek is commonly used in individuals with vitamin B12 or folate deficiencies, people with diabetic neuropathy, or those experiencing fatigue, numbness, or tingling in the limbs due to nerve imbalances.

It is particularly suited for individuals at risk of B-vitamin deficiency, such as vegetarians, elderly patients, people with diabetes, chronic alcohol users, or those on long-term medications like metformin or anticonvulsants. Homochek may also benefit patients recovering from illness or surgery and those with high physical or mental stress levels. The combination of active ingredients is formulated to promote nerve regeneration, reduce neuropathic discomfort, and support cognitive and cardiovascular well-being.

The recommended dose is usually one capsule daily, taken with or after meals, as advised by a healthcare provider. To get the most benefit, take it at a consistent time each day. Avoid taking it with tea, coffee, or high-fibre foods, which may interfere with absorption. Inform your doctor if you are on other medications, as some drug interactions may occur (e.g., with phenytoin, levodopa, or methotrexate). Do not exceed the recommended dose without medical advice.

Homochek Capsule is generally safe but may cause mild side effects like nausea, bloating, or headache in some users. It can be used during pregnancy or breastfeeding under medical supervision, especially when additional folic acid and B12 are needed. However, always consult your doctor before use in these cases. Store the capsule in a cool, dry place and keep it out of reach of children. Regular monitoring of vitamin levels may be advised during prolonged use.

Uses Of HOMOCHEK CAPSULE

• Helps manage vitamin B6, B9 and B12 deficiencies
• Supports control of high homocysteine levels
• Aids in nerve health and function
• Beneficial in anaemia related to vitamin B12 or folate deficiency
• Supports heart and brain health through improved metabolism

Benefits of HOMOCHEK CAPSULE

Homochek Capsule Use in Daily Nutrition

Homochek Capsule can be a helpful addition to daily nutrition, especially for individuals with dietary gaps or increased nutritional demands. It combines folic acid, pyridoxine and vitamin B12 nutrients that support red blood cell formation, energy production, and overall wellness. It may benefit people with unbalanced diets, busy lifestyles, or those recovering from illness. Daily use should follow healthcare guidance to maintain optimal nutrient levels safely

Homochek Capsule: Folic acid Support and Vitamin B12 Needs

Homochek Capsule is specially formulated to help meet folic acid and vitamin B12 requirements. Folic acid is essential for the production and maintenance of new cells, including red blood cells and helps reduce homocysteine levels to support overall cell growth and healthy blood formation, while vitamin B12 supports nerve health and DNA synthesis. Homochek can be useful for individuals prone to low energy, fatigue, or those with higher nutritional needs due to age, dietary habits, or specific health conditions.

Homochek for Low Folic Acid Levels

Homochek Capsule may be suitable for individuals with low folic acid levels, as it contains folic acid along with pyridoxine and vitamin B12. Folic acid is important for healthy red blood cell production and supporting maternal health. However, it’s important to confirm folic acid deficiency through medical evaluation. Always take Homochek as advised by a healthcare provider, especially if you are pregnant, breastfeeding, or managing other medical conditions.

How HOMOCHEK CAPSULE Works

Mechanism of Action of Homochek

The mechanism of action of Homochek capsule is based on its three key vitamin components—methylcobalamin (vitamin B12), folic acid (vitamin B9), and pyridoxine (vitamin B6)—which work synergistically to support crucial physiological functions:

• Methylcobalamin (Vitamin B12): Acts as a cofactor for the enzyme methionine synthase, facilitating the transfer of methyl groups to convert homocysteine into methionine. This reduces homocysteine levels, which helps prevent cardiovascular and neurological damage. It also supports normal red blood cell production by promoting nucleic acid synthesis and maturation of erythrocytes, thereby preventing megaloblastic anemia. Additionally, it supports proper functioning of the brain and nervous system.

• Folic Acid (Vitamin B9): Essential for DNA synthesis and repair, folic acid supports the formation and maintenance of new cells, especially rapidly dividing cells such as red blood cells. It works together with vitamin B12 to lower homocysteine levels by remethylation, which helps reduce cardiovascular risk and supports healthy blood formation.

• Pyridoxine (Vitamin B6): Involved in protein metabolism and acts as a coenzyme in the conversion of homocysteine to cystathionine via the transsulfuration pathway, further lowering homocysteine concentrations. It also plays a role in neurotransmitter synthesis (e.g., serotonin and dopamine) and supports nerve health and immune function.

How Does Vitamin B12 Function in the Body

Vitamin B12 plays a vital role in maintaining the health of nerves and blood cells. It is essential for DNA synthesis, supports brain function, and helps in the formation of red blood cells. A lack of B12 can lead to fatigue, nerve issues, and megaloblastic anaemia. In Homochek capsule, vitamin B12 complements iron and folic acid to support complete blood health and energy levels.

How to use HOMOCHEK CAPSULE

How Do I Take Homochek Capsule

• Take Homochek Capsule exactly as prescribed by your healthcare provider.
• Swallow the capsule whole with a glass of water; do not chew or crush it.
• Usually taken once daily try to take it at the same time each day.
• Do not skip doses or take more than the recommended amount.
• Complete the full course even if symptoms improve early.

Should Homochek Capsule Be Taken Before or After Food

• Homochek Capsule can be taken with or without food.
• It is generally recommended to take the capsule after food to:
  • Enhance absorption of the vitamins.
  • Reduce the risk of stomach upset or gastrointestinal discomfort.
• Taking it after meals may improve the bioavailability of methylcobalamin, folic acid and pyridoxine.
• Follow your doctor’s instructions regarding the timing and dosage.
• Take the capsule at a consistent time daily for optimal effectiveness.

What if I forgot to take HOMOCHEK CAPSULE

• If you miss a dose of Homochek Capsule, take it as soon as you remember.
• If it’s almost time for your next scheduled dose, skip the missed one do not double the dose.
• Avoid taking two capsules at once to make up for the missed dose.
• Try to take the capsule at the same time daily to build a routine.
• If you miss doses frequently, set reminders or speak with your doctor for guidance.3

Overdose

If you or anyone else accidentally took more HOMOCHEK CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include nausea, vomiting, stomach pain, dizziness, or confusion.

Side Effects Of HOMOCHEK CAPSULE

Common side effects of Homochek Capsule:

• Stomach discomfort
• Headache
• Skin rash, itching, redness
• Dizziness
• Nausea, vomiting

When to Seek Medical Attention?

Stop taking Homochek capsule and contact your physician immediately if you experience any of the following side effects:

• Swelling of face, lips, tongue, or throat
• Difficulty breathing or wheezing
• Severe skin rash, hives, or itching
• Seizures or sudden jerky movements
• Chest pain, palpitations, or tightness
• Unusual tiredness, confusion, or vision changes
• High fever or persistent sore throat

How To Manage Side Effects

Dizziness Or Drowsiness

• If dizziness occurs suddenly, lie down in a quiet, dark room and close your eyes.
• Ginger may support circulation and reduce queasy or lightheaded feelings.
• Sip on warm ginger tea or chew a small piece of raw ginger (if comfortable) once or twice a day.

Headache

• Dehydration is a common cause of headaches.
• Drink a glass of water and continue sipping fluids throughout the day

Nausea And Vomiting

• Smelling or sipping lemon juice in warm water can calm the stomach.
• Add honey if needed. Avoid if you have acidity.

Skin rash Or Itching

• Apply a clean, soft cloth soaked in cold water to the rash for 10–15 minutes.
• Helps reduce inflammation, itching, and redness quickly.
• If the symptom does not improve, contact your doctor immediately.

Warning & Precautions

Pregnancy

Consult your doctor

Homochek Capsule may be used during pregnancy if prescribed by a doctor. Folic acid are often required in pregnancy but dosage should be monitored to avoid excess intake. Always consult your healthcare provider before starting.

Breastfeeding

Consult your doctor

Homochek Capsule may be considered safe during breastfeeding, as folic acid and vitamin B12 are essential during this phase. However, it should only be used under medical supervision to ensure appropriate dosing.

Driving and Using Machines

Use with Caution

Homochek is unlikely to affect your ability to drive or use machinery. However, if you experience dizziness or fatigue, avoid such activities and inform your doctor.

Kidney

Use with Caution

Homochek capsule should be used with caution in individuals with kidney disorders. Always follow your doctor's advice.

Liver

Use with Caution

Patients with liver issues should use Homochek cautiously. Medical guidance is important to ensure safe use.

Allergy

Contraindicated

Do not take Homochek Capsule if you are allergic to any of its ingredients (Folic acid, pyridoxine or vitamin B12). Signs of an allergic reaction include rash, itching, swelling, or difficulty breathing seek immediate help if these occur.

Lungs

Homochek does not directly affect lung function. However, if you have breathing problems or are on long-term medications, consult your doctor before use.

Heart Disease

Use with Caution

Homochek capsule should be used with caution in individuals with heart conditions. Consult your doctor before taking it.

Use In Pediatrics

Consult your doctor

Homochek Capsule is generally not recommended for children unless specifically prescribed by a paediatrician. Accidental ingestion can be harmful store out of children's reach. 

Use In Geriatrics

Consult your doctor

Older adults may benefit from the nutrients in Homochek, especially if they have deficiencies. However, dosing should be monitored as absorption and metabolism may vary with age. 

Other Warnings for HOMOCHEK CAPSULE

Before taking homochek capsule inform your doctor if you have

• have iron overload disorders (e.g., hemochromatosis or hemosiderosis)
• have pernicious anaemia or other vitamin B12.
• have peptic ulcer disease or inflammatory bowel conditions like ulcerative colitis or Crohn’s disease.
• have undergone frequent blood transfusions.

Who should not take [GBNKEYWORD

Homochek capsule is not recommended for use if you have or had:

• Rare hereditary problems of galactose intolerance, fructose intolerance, or vitamin B12 malabsorption, unless supervised by a doctor.

Safety Advice

• Always read the label and leaflet provided with the medicine before use.
• Use Homochek Capsule only for the duration prescribed do not continue long-term unless advised.
• Avoid taking Homochek with other supplements containing Vitamin B6, B9, or B12 unless recommended.
• Discuss your complete medical history, including current supplements or herbal products, before starting.

Diet and Lifestyle Advice

• Include folate-rich foods in your meals such as spinach, lentils, broccoli, and citrus fruits.
• Eat foods high in Vitamin B12, like eggs, dairy, meat, and fortified cereals.
• Add whole grains, beans, and green leafy vegetables to support B-vitamin absorption.
• Limit intake of processed foods and sugary snacks, which may deplete vitamin levels.
• Drink plenty of water daily to stay hydrated and support metabolic functions.
• Engage in regular physical activity like walking, yoga, or stretching to improve blood flow and nutrient utilization.
•  Practice stress management (e.g., meditation or deep breathing), as stress can lower vitamin B levels.
•  Ensure adequate sleep (7–8 hours per night) to support overall recovery and wellness.
• Stop smoking, as it reduces the effectiveness of B-vitamins in the body.

1. Comparison table between Homochek Capsule and Folvite MB Tablet

2. Comparison table between Homochek Capsule and Folinext Gold Capsule

Drug - Drug interaction

1. Anticonvulsants (e.g., Phenytoin, Phenobarbital, Carbamazepine)

Interaction:
Long-term use of anticonvulsants can reduce folic acid and vitamin B6 levels. In turn, high doses of folic acid in Homochek may interfere with phenytoin effectiveness.
Management:
Monitor phenytoin levels if folic acid supplementation is needed. Adjust dosage if seizures become uncontrolled. Regular vitamin level assessments in patients on long-term anticonvulsants

2. Levodopa (used in Parkinson’s disease)

Interaction:
Pyridoxine (Vitamin B6) in Homochek may reduce the effectiveness of levodopa if taken without a dopa decarboxylase inhibitor (like carbidopa).
Management:
 Avoid taking high-dose pyridoxine with plain levodopa. Safe to use if the patient is on levodopa + carbidopa combination therapy. Clinical supervision advised when used concurrently

3. Methotrexate

Interaction:
Methotrexate interferes with folic acid metabolism, and folic acid supplementation in Homochek can reduce methotrexate-related side effects but may reduce its effectiveness in cancer therapy.
Management:
Folic acid is recommended in low-dose methotrexate therapy for rheumatoid arthritis. Avoid folic acid with methotrexate in cancer treatment unless advised. Coordinate with physician regarding timing and dosing

4. Proton Pump Inhibitors (e.g., Omeprazole, Pantoprazole)

Interaction:
Chronic use of PPIs may reduce absorption of Vitamin B12 in Homochek due to reduced stomach acid.
Management:
Consider B12 level testing in long-term PPI users. Intramuscular B12 may be required if oral absorption is impaired. Use Homochek at a different time from PPIs if possible

5. Metformin (used for Diabetes)

Interaction:
Metformin can reduce the absorption of Vitamin B12 over long-term use.
Management:
Monitor B12 levels regularly in patients taking metformin. Supplementation with Homochek can help restore levels. Intramuscular B12 may be needed in severe deficiencies

6. Chloramphenicol

Interaction:
Chloramphenicol can inhibit the red blood cell–producing effect of Vitamin B12 in Homochek.
Management:
Avoid combination unless necessary. Monitor blood counts regularly during co-administration. Use alternative antibiotics if prolonged therapy is expected

7. Oral Contraceptives

Interaction:
Can reduce serum levels of folic acid and Vitamin B6.
Management:
Supplementation through Homochek is beneficial. No major interaction risk, but monitor for symptoms of deficiency. Long-term users may need periodic nutrient assessment

Drug - Food interaction

1. High-Fiber Foods (e.g., bran, whole grains)

Interaction:
Dietary fibre may bind to vitamins, especially folic acid and B12, reducing their absorption in the gut.
Management:
Take Homochek Capsule 1–2 hours before or after consuming high-fibre meals. Avoid taking it immediately with fibre-rich drinks (like psyllium husk)

2. Dairy Products (e.g., milk, cheese, curd)

Interaction:
Excessive calcium in dairy can reduce absorption of certain vitamins and minerals, including folic acid and B12.
Management:
Maintain a 1–2-hour gap between Homochek and high-calcium foods. Moderate dairy intake if using supplements daily

3. Tea and Coffee (Caffeine-containing drinks)

Interaction:
Caffeine and tannins in tea/coffee may interfere with the absorption of B-vitamins like B12 and folic acid.
Management:
Avoid taking Homochek with or immediately after tea or coffee Maintain at least a 1-hour gap between supplement and caffeine intake

4. Vitamin C-Rich Foods (e.g., citrus fruits, juices)

Interaction:
Vitamin C may enhance the absorption of certain B-vitamins, especially folic acid (if present in the formula).
Management:
Can be taken alongside vitamin C–rich foods for better absorption. However, avoid acidic juices if the patient has gastric sensitivity

5. Protein-Rich Foods (e.g., meat, eggs, legumes)

 Interaction:
These foods may enhance Vitamin B12 absorption, but excessive protein or animal fat may interfere with other nutrient balance.
 Management:
 No harmful interaction – generally safe. Ensure a balanced protein intake if on multiple supplements

6. Antinutrient-Rich Foods (e.g., raw spinach, soybeans, legumes)

Interaction:
These contain compounds like phytates and oxalates that can reduce the bioavailability of vitamins and minerals.
Management:
Cook such foods to reduce antinutrient content. Take Homochek separately from raw antinutrient-rich meals

7. Grapefruit or Grapefruit Juice

Interaction:
Grapefruit may interfere with the metabolism of alpha-lipoic acid or other fat-soluble components in Homochek
Management:
Avoid grapefruit or maintain a 3–4. hour gap. Read the label to check for fat soluble ingredients.

Synopsis

More Information

FAQs About HOMOCHEK CAPSULE

Q: What is Homochek Capsule used for?

A: Homochek Capsule is a nutritional supplement used to support nerve health, improve energy levels, and maintain healthy blood and vitamin levels. It contains important B-complex vitamins like methylcobalamin, folic acid, and vitamin B6.

Q: How should I take Homochek Capsule?

A: Take Homochek Capsule as advised by your doctor, usually once daily. Swallow it whole with a glass of water. It is best taken after meals for better absorption.

Q: Can Homochek Capsule be taken daily?

A: Yes, Homochek is often taken daily for a few weeks or months, depending on your vitamin needs. Always follow your doctor’s recommended duration and dosage.

Q: Does Homochek Capsule cause side effects?

A: It is usually well-tolerated. Some people may experience mild side effects like nausea, bloating, or headache. Serious side effects are rare but consult your doctor if you feel unwell.

Q: Can I take Homochek Capsule with food?

A: Yes, you can take it with or after meals. Avoid taking it with tea, coffee, or high-fibre foods as they may affect vitamin absorption.

Q: How long should I take Homochek Capsule?

A: The duration depends on your health condition. Some people take it for weeks, others for longer. Follow your doctor’s instructions for best results.

Q: Can I drive after taking Homochek Capsule?

A: Homochek generally does not affect your ability to drive. However, if you feel dizzy or drowsy after taking it, avoid driving and consult your doctor.

Q: What are the common side effects of Homochek Capsule?

A: Mild side effects may include nausea, stomach upset, or a metallic taste in the mouth. These are temporary and usually go away on their own.

Q: Can Homochek Capsule be used for hair and skin health?

A: Though mainly used for nerve and blood health, B-vitamins also support hair growth and skin repair. It may offer general skin and hair benefits.

Q: Does Homochek Capsule cause weight gain?

A: No, it does not cause weight gain. It is a vitamin supplement and has no direct effect on body weight.

Q: Can I stop taking Homochek Capsule suddenly?

A: Yes, you can stop it if advised by your doctor. There are no withdrawal symptoms, but stopping too early may reduce its benefits.

References

1.Tripathi, K.D. Vitamins: Hematinics – Role of Vitamin B12, Folic Acid, and. Essentials of Medical Pharmacology, Seventh Edition. 2013. Page – 600. Pyridoxine in lowering homocysteine levels

2.Stanger O. Vitamin B12, folic acid, and the nervous system. In: Advances in Nutrition and Neurology. 2nd edition. New York, NY: Springer; 2019. p. 112-130.

3.Homocysteine-Lowering Therapy with Folic Acid and B Vitamins: Clinical Trial Data. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; revised 20 March 2024 [Accessed on 28th July 2025].

4.Vitamin B12 Fact Sheet for Health Professionals. National Institutes of Health (NIH) Office of Dietary Supplements. Revised 2 July 2025 [Accessed on 28th July 2025].

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Shruthi Raikar - BDS

Last updated on 29 Jul 2025 | 12:29 PM(IST)