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Introduction About GLIZID MV TABLET
GLIZID MV TABLET is a combination of Gliclazide, Metformin, and Voglibose, called Antidiabetic agents. It manages type II diabetes in patients whose blood sugar level is not controlled by diet alone.
Your doctor may advise you to take a blood and urine sugar level test before or along with the management. Do not take GLIZID MV TABLET if you have severe liver, kidney, and heart problems. GLIZID MV TABLET is not advised for use in pregnant and breast-feeding women. Consult your doctor before taking.
GLIZID MV TABLET is not recommended for use in children, and it should be used with caution in elderly patients.
Common side effects of taking GLIZID MV TABLET are headache, nausea, constipation, indigestion, diarrhea, and abdominal pain. Consult your doctor if the side effects do not improve.
Uses Of GLIZID MV TABLET
- Manages type II diabetes mellitus
Benefits of GLIZID MV TABLET
- Combination of Metformin, Gliclazide, Voglibose for daily blood glucose support
- Convenient oral dosing for adults with type 2 diabetes
- Sustained release formulation for steady effect
- Helps maintain post-meal glucose balance
How GLIZID MV TABLET Works
The mechanism of action of GLIZID MV TABLET involves a triple combination of active ingredients Metformin, Gliclazide, and Voglibose, that work together to regulate blood glucose levels in people with type 2 diabetes through distinct pathways:
- Metformin: Decreases glucose production in the liver, reduces glucose absorption from the intestines, and improves insulin sensitivity, allowing the body to use available insulin more effectively.
- Gliclazide: Stimulates the beta cells of the pancreas to release more insulin, which helps lower blood sugar levels.
- Voglibose: Acts as an alpha-glucosidase inhibitor that delays the digestion and absorption of carbohydrates in the intestines, thereby preventing rapid spikes in blood glucose after meals.
Together, these three components provide comprehensive blood sugar regulation by targeting insulin secretion, insulin sensitivity, and carbohydrate absorption, helping to maintain blood glucose within a healthy range when combined with lifestyle measures like diet and exercise
How to use GLIZID MV TABLET
- GLIZID MV Tablet should be taken exactly as prescribed by your healthcare provider.
- Swallow the tablet whole with a glass of water or milk.
- Do not chew, crush, or break the tablet as it is designed for sustained release to maintain steady blood sugar control.
- It is recommended to take the tablet with meals, preferably just before or during food intake, to reduce gastrointestinal side effects and optimize effectiveness.
- Consistent daily timing improves steady blood levels for better glucose management.
Dosage Guidance for Adults and Elderly
- Adults typically start with one tablet daily, which may be increased based on response and tolerance.
- Elderly patients or those with decreased kidney function should have doses carefully adjusted to minimize risks like hypoglycemia.
- Regular consultation with your healthcare provider helps ensure that the dosage is appropriate and safe.
Daily Intake and Timing Instructions
- GLIZID MV is most effective when taken daily at consistent times in relation to meals, usually once or twice per day.
- Taking the tablet with meals reduces potential side effects and supports better glucose absorption control.
- Do not alter the dosing schedule without medical advice.
What if I forgot to take GLIZID MV TABLET
- If a scheduled dose is missed, take the tablet as soon as you remember unless it is near your next dose time.
- Avoid taking two doses simultaneously to prevent low blood sugar episodes.
- If unsure, contact your healthcare provider or pharmacist for guidance.
Overdose
If you or anyone else accidentally used too much of GLIZID MV TABLET, consult your doctor immediately or visit any nearby hospital. Symptoms of an overdose are low blood sugar, such as sweating, trembling, weakness, double vision, palpitations, confusion, and symptoms of lactic acidosis that are non-specific, such as vomiting, abdominal pain with muscle cramps, a feeling of being unwell with severe tiredness, and difficulty breathing.
Side Effects Of GLIZID MV TABLET
Common
- nausea, vomiting, diarrhoea, abdominal pain, indigestion, constipation
- loss of appetite
- altered taste sensation
- skin rashes, pale skin, redness, itching, and hives
- signs of low sodium levels like whole body dizziness, fatigue, lethargy, weakness, or thirst
When to consult your doctor?
- allergic reaction like skin rash or angioedema (rapid swelling of tissues such as the eyelids, face, lips, mouth, tongue, or throat that may result in breathing difficulty)
- flu-like symptoms and a rash on the face, then an extended rash with a high temperature, the rash progressing to widespread blistering or peeling of the skin
- hepatitis or liver failure causing fatigue, excessive tiredness, weakness, loss of appetite, weight loss, fever, changes in liver enzymes, and jaundice (yellowing of the skin or whites of the eyes)
- lactic acidosis
Warning & Precautions
Pregnancy
ContraindicatedGLIZID MV TABLET is not advised for use by pregnant women. Consult your doctor before taking it.
Breastfeeding
ContraindicatedGLIZID MV TABLET is not advised for use by breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionGLIZID MV TABLET does not affect your ability to drive or operate any machinery. Take special care while driving or operating machines since it may cause difficulty in concentration.
Alcohol
Consult your doctorDo not consume alcohol while taking GLIZID MV TABLET, as it may increase the risk of side effects.
Kidney
ContraindicatedGLIZID MV TABLET is not advised for use in patients with severe kidney problems. Consult your doctor before taking GLIZID MV TABLET.
Liver
ContraindicatedGLIZID MV TABLET is not advised for use in patients with severe liver problems. Consult your doctor before taking GLIZID MV TABLET.
Allergy
ContraindicatedDo not take GLIZID MV TABLET if you are allergic to Gliclazide, Metformin, Voglibose, or any ingredients of this medicine.
Lungs
ContraindicatedGLIZID MV TABLET is not advised for use in patients with lung or bronchial infections.
Heart Disease
ContraindicatedGLIZID MV TABLET is not advised for use in patients with acute heart failure or who have recently had a heart attack.
Use In Pediatrics
ContraindicatedGLIZID MV TABLET is not advised for use with children. Consult your doctor for advice before taking the medicine.
Use In Geriatrics
Use with CautionGLIZID MV TABLET should be used cautiously with elderly patients. Consult your doctor for advice.
Other Warnings for GLIZID MV TABLET
Before taking GLIZID MV TABLET, inform your doctor if you:
- have an inherited condition where your red blood cells do not produce enough of the enzyme G6PD (glucose-6 phosphate dehydrogenase)
- have hormone-induced disorders such as functional disorders of the thyroid gland, pituitary gland, or adrenal cortex
- have low blood sugar (hypoglycaemia)
- have lactic acidosis
Who should not take [GBNKEYWORD
GLIZID MV TABLET is not recommended for use if you:
- have porphyria (a disorder of red blood cells)
- have diabetes ketoacidosis
- have type 1 diabetes
- have to undergo any operation or have previously suffered from severe trauma or infection
- have severe hyperglycemia (high blood glucose)
- have dehydration problems
- have gastrointestinal obstruction
Diet and Lifestyle Advice
- Balanced Diet: Focus on a diet rich in whole grains, vegetables, lean proteins, and healthy fats. Limit intake of refined sugars, processed foods, and high-fat meals to help maintain steady blood glucose levels.
- Meal Timing: Eat meals and snacks at regular intervals to avoid blood sugar spikes and dips. Taking GLIZID MV Tablet with or just before meals enhances its effectiveness.
- Carbohydrate Management: Choose complex carbohydrates, such as brown rice, oats, and beans, which digest slower and help prevent rapid blood sugar increases.
- Hydration: Drink plenty of water throughout the day to support kidney function and overall metabolic health.
- Physical Activity: Incorporate regular moderate exercise like walking, cycling, or swimming for at least 30 minutes most days of the week. Exercise improves insulin sensitivity and aids glucose utilization.
- Weight Management: Maintaining a healthy weight through diet and exercise can improve blood sugar control and reduce the risk of diabetes complications.
- Avoid Alcohol and Smoking: Limit or avoid alcohol, as it can interfere with blood sugar control and medication tolerance. Smoking cessation is highly recommended to improve cardiovascular health.
- Stress Management: Practice relaxation techniques such as yoga, meditation, or deep breathing to manage stress, which can impact blood sugar levels.
- Regular Monitoring: Keep track of blood sugar levels as advised by your healthcare provider and report any unusual symptoms promptly.
|
Feature |
GLIZID MV TABLET |
Metformin Monotherapy |
Gliclazide Monotherapy |
Voglibose Monotherapy |
|
Main Ingredients |
Metformin + Gliclazide + Voglibose |
Metformin |
Gliclazide |
Voglibose |
|
Type of Drug |
Fixed-dose combination |
Single active ingredient |
Single active ingredient |
Alpha-glucosidase inhibitor |
|
Mechanism of Action |
Multi-pathway: Liver glucose reduction, insulin stimulation, carbohydrate absorption delay |
Reduces liver glucose production, improves insulin sensitivity |
Stimulates insulin release |
Slows carbohydrate digestion |
|
Typical Use |
When dual therapy needs enhancement |
First-line therapy for type 2 diabetes |
For controlling blood sugar alone or with other agents |
To control post-meal blood sugar spikes |
|
Dosing Frequency |
Usually once or twice daily |
Once or twice daily |
Once or twice daily |
Usually once daily |
|
Benefits |
Comprehensive blood sugar control, reduces post-meal spikes |
Effective for initial management |
Good for basal control |
Reduces carbohydrate absorption, prevents spikes |
|
Side Effects |
Hypoglycemia, gastrointestinal upset, rash |
Gastrointestinal issues, lactic acidosis risk |
Hypoglycemia, weight gain |
Gastrointestinal discomfort, flatulence |
|
Suitable for |
Adults with type 2 diabetes requiring combination therapy |
All ages, first-line therapy |
Suitable alone or in combination |
Adjunct in post-meal blood sugar management |
|
Monitoring Needed |
Blood glucose, kidney, liver functions |
Blood glucose, kidney function |
Blood glucose, kidney function |
Blood sugar, gastrointestinal health |
Drug - Drug interaction
GLIZID MV Tablet contains Metformin, Gliclazide, and Voglibose, and it is important to be aware of potential interactions when taking this medication alongside other drugs:
- Other Antidiabetic Agents: Combining GLIZID MV with insulin, sulfonylureas (like glimepiride), or other oral diabetes medicines may increase the risk of low blood sugar (hypoglycemia). Dosage adjustments may be necessary under medical supervision.
- Cardiovascular and Blood Pressure Medications: Some blood pressure medicines (like ACE inhibitors), diuretics, and beta-blockers can alter blood sugar control and interact with GLIZID MV.
- Anticoagulants (Blood Thinners): Medications like warfarin may have altered effects when used with GLIZID MV, requiring close monitoring.
- Drugs Affecting Liver Enzymes: Certain drugs such as corticosteroids, thyroid products, phenothiazines, and estrogen-containing medicines can affect how GLIZID MV works and blood sugar levels.
- Specific Drugs to Inform Your Doctor About: Cimetidine, digoxin, morphine, quinidine, ranitidine, captopril, enalapril, isocarboxazid, phenelzine, clofibrate, and gemfibrozil may interact with GLIZID MV.
Always inform your healthcare provider about all medications, supplements, or herbal products you use to avoid harmful interactions and ensure safe treatment.
Synopsis
| Drug | : | Gliclazide, Metformin, Voglibose |
| Pharmacological Category | : |
Sulfonylureas, biguanides, and alpha-glucosidase inhibitors |
| Therapeutic Indication | : | Type II diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
Expert Backed Decision Guidance
- Choose GLIZID MV when dual therapy have not controlled glucose adequately
- Suitable for adults with type 2 diabetes requiring combination management
- Best when combined with doctor-recommended lifestyle changes
FAQs About GLIZID MV TABLET
Q: What is GLIZID MV TABLET and why is it given?
A: GLIZID MV TABLET contains Gliclazide, Metformin, and Voglibose, which are collectively used to manage type II diabetes (noninsulin-dependent diabetes) in patients whose blood sugar level is not controlled by diet alone.
Q: Can I drink alcohol while taking GLIZID MV TABLET?
A: Avoid alcohol consumption while taking GLIZID MV TABLET, as it may increase the risk of side effects. Consult your doctor for advice.
Q: Is GLIZID MV TABLET safe for pregnant and breast-feeding women?
A: GLIZID MV TABLET is not advised for use in pregnant women, if you are planning to become pregnant, or in breast-feeding women. Consult your doctor before taking it.
Q: Is GLIZID MV TABLET safe for use by children?
A: GLIZID MV TABLET is not advised for use with children. Your physician will prescribe you any other suitable medicine. Consult your doctor for advice before taking GLIZID MV TABLET.
Q: Does GLIZID MV TABLET cause skin rashes?
A: Yes, it may cause skin rash in some. Try to avoid hot showers because they may cause skin irritation. Avoid frequent contact with and rubbing over the affected area. Use sunscreen and protective clothing when outdoors.
Q: How should I take GLIZID MV Tablet?
A: Take the tablet exactly as prescribed by your healthcare provider, usually once or twice daily with meals. Swallow whole without crushing or chewing to ensure proper release and absorption.
Q: What should I do if I miss a dose?
A: If you miss a dose, take it as soon as you remember unless it’s close to the next dose. Do not double the dose to make up for a missed one. Consult your doctor if unsure.
Q: Are there any side effects I should be aware of?
A: Common side effects may include low blood sugar (hypoglycemia), nausea, diarrhea, headache, and dizziness. If you experience severe or persistent symptoms, contact your healthcare provider.
Q: Is GLIZID MV suitable for elderly patients?
A: Yes, but elderly patients should use GLIZID MV under medical supervision, as dosage may need adjustment and careful monitoring because of increased sensitivity to side effects.
References
1. KD. Tripathi. Oral Antidiabetic drugs. Essentials of medical pharmacology. Eighth edition. 2019. Page – 294.
2. Yi-Wei Wang, Si-Jia He, Xiao Feng, Jin Cheng, Yun-Tao Luo, Ling Tian, and Qian Huang. Metformin: a review of its potential indications. NIH National Library of Medicine, National Center for Biotechnology Information PubMed Central. August 2011. [Accessed on 19th September 2025] 
3. Gijs W. D. Landman,Geertruide H. de Bock,Kornelis J. J. van Hateren, Peter R. van Dijk, Klaas H. Groenier, Rijk O. B. Gans, Sebastiaan T. Houweling, Henk J. G. Bilo, and Nanne Kleefstra. Safety and Efficacy of Gliclazide as Treatment for Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Trials. NIH National Library of Medicine, National Center for Biotechnology Information PubMed Central. February 2014. [Accessed on 19th September 2025] 
4. Accord, Barnstaple. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed on 19th September 2025]
5. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in June 2020] [Accessed 19th September 2025]
6. Biocon Limited. [Accessed 19th September 2025]
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