New Revised MRP, 100% GST benefit passed GEN D3 6L INJECTION 1ML
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Introduction About GEN D3 6L
GEN D3 6L contains Cholecalciferol (Vitamin D3) which belongs to the group of medicines called Vitamin D analogs. It is used for the prophylaxis of vitamin D deficiency symptoms due to malabsorption (Ex. caused by chronic intestinal diseases, scarred alteration of the liver tissue (biliary hepatocirrhosis), extended stomach or intestines resections) or if an oral therapy is impossible or ineffective.
Along with this management, your doctor might advise you to eat and drink foods that are rich in calcium. Your doctor might want to take certain blood tests prior to the management to understand the existing condition.
GEN D3 6L is not recommended for use if you have high levels of calcium in the blood (hypercalcemia) or urine (hypercalciuria), tend to form kidney stones having calcium, suffer from hereditary dysfunction of the excretion of phosphate (pseudohypoparathyroidism).
Before receiving GEN D3 6L inform your doctor if your kidney excretion of calcium and phosphate is impaired, your mobility is reduced (Ex. due to a cast), suffer from sarcoidosis (a multisystem chronic inflammatory condition which can affect your lungs, heart and kidneys).
GEN D3 6L is not recommended for use in pregnant and breastfeeding women. Inform your doctor immediately if you experience any unusual symptoms during management with this medicine.
Uses Of GEN D3 6L
Used for the:
- Prophylaxis of vitamin D deficiency (due to malabsorption or if an oral therapy is not possible)
How GEN D3 6L Works
GEN D3 6L helps the body to absorb calcium and phosphorus by increasing their absorption from the gut and reducing the amount removed by the kidneys and is a fat-soluble vitamin.
How to use GEN D3 6L
GEN D3 6L will be given to you by your doctor or a nurse as an injection into a muscle (intramuscularly). Your doctor will decide the right dose and duration for you depending on your age, body weight and disease condition.
Side Effects Of GEN D3 6L
Rare
Inform your doctor immediately if you experience any of the following side effects while receiving GEN D3 6L:
- hypercalcemia (increased calcium concentration in the blood)
- symptoms of impaired kidney function
Warning & Precautions
Pregnancy
GEN D3 6L is not recommended for use in pregnant women or women planning to have a baby as an overdosage of this medicine can lead to physical and mental retardation as well as to congenital heart and eye diseases of the child. Consult your doctor before receiving it.
Breastfeeding
GEN D3 6L is not recommended for use in breastfeeding women. Consult your doctor before receiving it.
Driving and Using Machines
GEN D3 6L does not affect your ability to drive or use machines. Consult your doctor for advice.
Kidney
GEN D3 6L is not recommended for use in patients with kidney problems who tend to form kidney stones with calcium. GEN D3 6L should be used with caution in patients with impaired kidney excretion of calcium and phosphate. Consult your doctor before receiving it.
Allergy
Do not receive GEN D3 6L if you are allergic to Cholecalciferol or any other ingredients of this medicine.
Others
GEN D3 6L is not recommended for use if you:
- have high levels of calcium in the blood or urine
- suffer from hereditary dysfunction of the excretion of phosphate (pseudohypoparathyroidism)
Before receiving GEN D3 6L, inform your doctor if you:
- your mobility is reduced (Ex. due to a cast)
- suffer from sarcoidosis (a multisystem chronic inflammatory condition which can affect your lungs, heart, and kidneys)
Interactions
A. Drug-Drug Interactions:
Before receiving GEN D3 6L, inform your doctor, if you are taking any of the following medicines:
- medicines used to manage epilepsy (Ex. phenobarbital, phenytoin, primidone)
- other vitamin D containing medicines including multi-vitamins
- cardiac glycosides (used to increase the contraction force of the cardiac muscle) Ex. digoxin
- thiazide diuretics (water tablets) (Ex. benzothiadiazine)
- glucocorticosteroids (Ex. hydrocortisone or prednisolone)
Overdosage:
As GEN D3 6L is given by your doctor or nurse it’s unlikely for you to have an overdose. Consult your doctor immediately if you experience any unusual symptoms like nausea, vomiting, diarrhea, severe constipation, loss of appetite, weakness, headache, muscle and joint pain, muscle weakness as well as persistent drowsiness, azotemia (increased nitrogen concentration in blood), excessive thirst and increased urge to urinate, dehydration.
Synopsis
| Drug | : |
Cholecalciferol |
| Pharmacological Category | : |
Vitamin D analogs |
| Therapeutic Indication | : |
Vitamin D deficiency |
| Dosage Forms | : | Tablet, Chewable tablet, Disintegrating tablet, Disintegrating strip, Capsule, Softgel capsule, Injection, Oral solution, Syrup, Suspension, powder, Sachet, Oral drops, Nano drops, Oral Spray, Granules |
More Information
- Store GEN D3 6L at room temperature
FAQs About GEN D3 6L
What is GEN D3 6L used for?
GEN D3 6L is used for the prophylaxis of vitamin D deficiency symptoms due to malabsorption (Ex. caused by chronic intestinal diseases, scarred alteration of the liver tissue (biliary hepatocirrhosis), extended stomach or intestines resections) or if an oral therapy is impossible or ineffective.
How does GEN D3 6L work?
GEN D3 6L helps the body to absorb calcium and phosphorus and is a fat-soluble vitamin. It is produced naturally by your skin after exposure to the sun and is also found in some foods. GEN D3 6L is prescribed as a dietary supplement when there is a deficiency of Vitamin D or during increased requirement.
Can GEN D3 6L be used in pregnant women?
GEN D3 6L is not recommended for use in pregnant women or women planning to have a baby as an overdosage of this medicine can lead to physical and mental retardation as well as to congenital heart and eye diseases of the child. Consult your doctor before receiving it.
Can GEN D3 6L be used in patients with kidney problems?
GEN D3 6L is not recommended for use in patients with kidney problems who tend to form kidney stones with calcium. GEN D3 6L should be used with caution in patients with impaired kidney excretion of calcium and phosphate. Consult your doctor before receiving it.
How is GEN D3 6L administered?
GEN D3 6L will be given to you by your doctor or a nurse as an injection into a muscle (intramuscularly). Your doctor will decide the right dose and duration for you depending on your age, body weight and disease condition.
References
1. KD. Tripathi. Section 11, Vitamins. Essentials of medical pharmacology. Seventh edition. 2013. Page – 909.
2. Nair, Rathish, and Arun Maseeh. Vitamin D: The "sunshine" vitamin. National library of Medicine, National center for Biotechnology information. Pubmed Central. 2012. [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356951/
3. J Christopher Gallagher, Daniel D Bikle. Vitamin D: Mechanisms of Action and Clinical Applications.National library of Medicine, National center for Biotechnology information. Pubmed.gov 2017. [Accessed on 21st June 2022] Vitamin D: Mechanisms of Action and Clinical Applications - PubMed (nih.gov)
4. Ever Pharma Jena GmbH. D3-Vicotrat. (Vitamin D3 injection). [Revised in April 2018] [ Accessed on 21st June 2022] https://www.heyl-berlin.de/img_upload/pdf/PIL_D3-Vicotrat_EN_2018-04.pdf
Useful Diagnostic Tests
- Vitamin D3 test
- Kidney function test
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