Fosfofic 4Gm Injection 1'S
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Introduction About FOSFOFIC 4GM INJECTION
FOSFOFIC 4GM INJECTION contains Fosfomycin which belongs to a group of medicines called Antibiotics. It is used to manage certain infections in adults and children, including neonates, when the commonly recommended medicines have less or no efficacy. The infections include acute osteomyelitis, complicated urinary tract infections, nosocomial lower respiratory tract infections, bacterial meningitis, and bacteraemia associated with any of the listed infections.
FOSFOFIC 4GM INJECTION should be used with caution in patients with heart and kidney diseases, high blood pressure, hyperaldosteronism, high levels of sodium, pulmonary oedema, and liver cirrhosis. Contact your doctor before receiving it.
FOSFOFIC 4GM INJECTION should be used with caution during pregnancy. FOSFOFIC 4GM INJECTION can be given to children and adolescents. However, the dose and duration will be decided by the doctor. The most common side effects of FOSFOFIC 4GM INJECTION include retching, stomach ache, and a rash with skin redness. Contact your doctor if any of the symptoms worsen.
Uses Of FOSFOFIC 4GM INJECTION
It is used to manage certain infections in adults and children including neonates when the commonly recommended medicines have less or no efficacy. The infections include acute osteomyelitis, complicated urinary tract infections, nosocomial lower respiratory tract infections, bacterial meningitis and bacteraemia associated with any of the listed infections.
How FOSFOFIC 4GM INJECTION Works
FOSFOFIC 4GM INJECTION works by managing the enzymatic synthesis of the bacterial cell wall. It exerts a bactericidal effect on the bacteria and thereby helps manage the infection.
How to use FOSFOFIC 4GM INJECTION
FOSFOFIC 4GM INJECTION will only be given to you by a doctor or nurse. The dose and duration will be decided by your doctor depending on your age, body weight and disease severity.
Side Effects Of FOSFOFIC 4GM INJECTION
Common
- retching, stomach-ache
- rash with redness of skin
Uncommon
- nausea, vomiting, mild diarrhoea
- altered taste
- shortness of breath
- rash
- decreased appetite
- headache
- dizziness
- tiredness
- increased levels of liver enzymes
- swelling caused due to fluid retention
Rare
- pallor, weakness, or breathlessness
- eosinophilia (elevated white blood cell levels) associated with allergic diseases
Stop receiving FOSFOFIC 4GM INJECTION and contact your doctor immediately if you experience any of the following side effects:
- serious allergic reaction (symptoms include breathing or swallowing difficulties, sudden wheezing, dizziness, swelling of face, eyelids, lips and tongue, rash or itching)
- severe and persistent diarrhoea (may or may not be associated with abdominal pain or fever)
- jaundice (yellowish discolouration of skin or whites of eyes)
- confusion, muscle twitching or abnormal heart rhythm
- pain, burning, redness or swelling along the vein in which the medicine has been infused
- bleeding and bruising more often than usual
Warning & Precautions
Pregnancy
Use with CautionFOSFOFIC 4GM INJECTION should be used with caution in pregnant females. Contact your doctor before receiving it.
Breastfeeding
Use with CautionFOSFOFIC 4GM INJECTION should be used with caution in breastfeeding females as it may pass on to the breastmilk. Contact your doctor before receiving it.
Driving and Using Machines
ContraindicatedUse of FOSFOFIC 4GM INJECTION may cause dizziness, therefore it is not recommended to drive or use heavy machines while receiving this medicine.
Kidney
Use of FOSFOFIC 4GM INJECTION in patients with kidney diseases, especially patients undergoing dialysis may require dose reduction. Therefore, contact your doctor before receiving it.
Liver
Use with CautionFOSFOFIC 4GM INJECTION should be used with caution in patients with liver cirrhosis. Therefore, contact your doctor before receiving it.
Allergy
ContraindicatedDo not receive FOSFOFIC 4GM INJECTION if you are allergic to Fosfomycin or any other ingredients of this medicine
Lungs
Use with CautionFOSFOFIC 4GM INJECTION should be used with caution in patients with pulmonary oedema. Contact your doctor before receiving it.
Heart Disease
FOSFOFIC 4GM INJECTION should be used with caution in patients with heart diseases, and high blood pressure. Therefore, contact your doctor before receiving it.
Use In Pediatrics
Consult your doctorFOSFOFIC 4GM INJECTION can be given to children and adolescents. However, the dose and duration will be decided by the doctor. Therefore, contact your doctor before receiving it.
Use In Geriatrics
Use with CautionNo dose adjustment is required in elderly patients above 65 years of age before receiving FOSFOFIC 4GM INJECTION. Contact your doctor before receiving it.
Others
Before receiving FOSFOFIC 4GM INJECTION tell your doctor if you have:
- hyperaldosteronism
- high levels of sodium
Interactions
Overdosage:
FOSFOFIC 4GM INJECTION will be given to you by a doctor or nurse only so there is minimal chance of overdose. However, if you feel you are receiving extra dose of this medicine, contact your doctor immediately.
Synopsis
| Drug | : | Fosfomycin |
| Pharmacological Category | : | Antibiotics |
| Therapeutic Indication | : | Manage bacterial infection of lungs, bones, kidneys and bladder, brain |
| Dosage Forms | : | Injection, sachets |
More Information
- Keep FOSFOFIC 4GM INJECTION out of sight and reach from children
- Store FOSFOFIC 4GM INJECTION at 2-8°C
FAQs About FOSFOFIC 4GM INJECTION
Q: How does FOSFOFIC 4GM INJECTION works?
A: Fosfomycin works by managing the enzymatic synthesis of the bacterial cell wall. It exerts a bactericidal effect on the bacteria and thereby helps manage the infection.
Q: What are the common side effects of FOSFOFIC 4GM INJECTION?
A: The most common side effects of FOSFOFIC 4GM INJECTION include retching, stomach ache, and a rash with skin redness. Contact your doctor if any of the symptoms worsen.
Q: What are the precautions before receiving FOSFOFIC 4GM INJECTION?
A: FOSFOFIC 4GM INJECTION should be used with caution in patients with heart and kidney diseases, high blood pressure, hyperaldosteronism, high levels of sodium, pulmonary oedema, and liver cirrhosis. FOSFOFIC 4GM INJECTION should be used with caution. Contact your doctor before receiving it.
Q: What is FOSFOFIC 4GM INJECTION and how is it used?
A: FOSFOFIC 4GM INJECTION contains Fosfomycin, which belongs to a group of medicines called antibiotics. It is used to manage certain infections in adults and children, including neonates, when the commonly recommended medicines have less or no efficacy. The infections include acute osteomyelitis, complicated urinary tract infections, nosocomial lower respiratory tract infections, bacterial meningitis, and bacteraemia associated with any of the listed infections.
Q: Is FOSFOFIC 4GM INJECTION safe for use by children?
A: FOSFOFIC 4GM INJECTION can be given to children and adolescents. However, the dose and duration will be decided by the doctor. Therefore, contact your doctor before receiving it.
References
1. Karen Whalen. Cell Wall Inhibitors. Lippincott Illustrated Reviews Pharmacology. Sixth edition. 2015. Page 494.
2. Anneke Corinne Dijkmans, Natalia Veneranda Ortiz Zacarías, Jacobus Burggraaf, Johan Willem Mouton, Erik Bert Wilms, Cees van Nieuwkoop, Daniel Johannes Touw, Jasper Stevens, and Ingrid Maria Catharina Kamerling. Fosfomycin: Pharmacological, clinical, and future perspectives. [Published on Oct 2017] [Accessed on 24th Nov 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745467/
3. Ciplamed. [Revised in Jun 2016] [Accessed on 24th Nov 2022] https://www.ciplamed.com/content/crifos-4-gm-injection#:~:text=Fosfomycin%20is%20primarily%20excreted%20renally%20unchanged.&text=Individual%20doses%20must%20not%20exceed%208%20g.,-a&text=The%20high%2Ddose%20regimen%20in,caused%20by%20less%20susceptible%20bacteria.&text=There%20are%20limited%20safety%20data,excess%20of%2016%20g%2Fday.
4. Verity Pharmaceuticals. [Revised in May 2019] [Accessed on 24th Nov 2022] https://pdf.hres.ca/dpd_pm/00050889.PDF
5. Taj Pharmaceuticals Ltd. [Accessed on 24th Nov 2022] https://tajpharma.in/portfolio-item/fosfomycin-sodium-for-injection-4g/
6. Alniche Life sciences. [Accessed on 24th Nov 2022] https://www.alniche.com/product/fosfona/
7. Frenius Kabi. [Accessed on 24th Nov 2022] https://www.fresenius-kabi.com/in/products/fresofos
8. MIMS Indonesia. [Accessed on 24th Nov 2022] https://www.mims.com/indonesia/drug/info/fosmicin?type=full
Useful Diagnostic Tests
- Complete blood count (CBC)
- Liver function tests
- Kidney Function tests
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