New Revised MRP, 100% GST benefit passed Faslodex 250mg Injection 2X5ml
Netmeds First Membership
Quick Links
Introduction About FASLODEX 250MG INJECTION
FASLODEX 250MG INJECTION contains Fulvestrant which belongs to the group of Estrogen blockers. It is used for a type of breast cancer called estrogen receptor positive breast cancer in postmenopausal women that is locally advanced or has spread to other parts of the body (metastatic). This medicine is also used with combination with palbociclib for women with a type of breast cancer called hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer, that is locally advanced or has spread to other parts of the body (metastatic). Women who have not reached menopause will also be managed with a medicine called a luteinizing hormone releasing hormone (LHRH) agonist.
FASLODEX 250MG INJECTION is not recommended to use in patients with severe liver problems. Before receiving FASLODEX 250MG INJECTION, inform your doctor if you have or ever had kidney problems, liver problems, osteoporosis, low number of platelets, bleeding problems, or previous problems with blood clots.
Avoid consumption of alcohol while receiving FASLODEX 250MG INJECTION, as it may lead to unwanted side effects. FASLODEX 250MG INJECTION is not recommended for use in pregnant and breastfeeding women. The most common side effects of receiving FASLODEX 250MG INJECTION are headache, vomiting, diarrhea, loss of appetite, urinary tract infection, back pain, vaginal bleeding, and thromboembolism. Consult your physician if any of the symptoms worsen or persists for a longer duration.
Uses Of FASLODEX 250MG INJECTION
It is used for:
- a type of breast cancer called estrogen receptor positive breast cancer (in postmenopausal women)
- a type of breast cancer called hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer (in combination with other medicines)
How FASLODEX 250MG INJECTION Works
FASLODEX 250MG INJECTION blocks the action of estrogen on breast cancer cells which lowers the growth of some breast cancer cells that need estrogen to grow.
How to use FASLODEX 250MG INJECTION
FASLODEX 250MG INJECTION will be administered by your doctor or nurse. The correct dose and duration will be decided by your doctor depending on your age, body weight, and disease condition.
Side Effects Of FASLODEX 250MG INJECTION
Serious
Stop receiving FASLODEX 250MG INJECTION and contact your physician immediately if you experience any of the following side effects:
- injection site reactions, such as pain or inflammation
- elevated levels of liver enzymes
- weakness, tiredness
- joint and musculoskeletal pain
- hot flushes
- skin rash
- allergic reactions (symptoms like swelling of the face, lips, tongue, and/or throat)
Common
- headache
- vomiting
- diarrhea
- loss of appetite
- urinary tract infections
- back pain
- increase in bilirubin
- thromboembolism (increased risk of blood clots)
- decreased levels of platelets (thrombocytopenia)
- vaginal bleeding
- lower back pain irradiating to leg on one side (sciatica)
- peripheral neuropathy (sudden weakness, tingling, numbness, or loss of movement in the leg, especially on only one side of the body, sudden problems with walking or balance)
Uncommon
- infection of the vagina symptoms like thick, whitish vaginal discharge and candidiasis
- bruising and bleeding at the site of injection
- hepatitis (inflammation of the liver)
- liver failure
- numbness, tingling, and pain
- anaphylactic reactions
How To Manage Side Effects
Diarrhea
Drink more fluids like water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your physician.
Nausea And Vomiting
Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily-rich or spicy foods.
Warning & Precautions
Pregnancy
ContraindicatedFASLODEX 250MG INJECTION is not recommended for use in pregnant women. Consult your doctor for advice.
Breastfeeding
ContraindicatedFASLODEX 250MG INJECTION is not recommended for use in breastfeeding women as it may pass through breast milk. Consult your doctor for advice.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel tired after receiving FASLODEX 250MG INJECTION.
Alcohol
Consult your doctorAvoid consumption of alcohol while receiving FASLODEX 250MG INJECTION. Consult your doctor for advice.
Kidney
Use with CautionFASLODEX 250MG INJECTION should be used with caution in patients with kidney disease. Consult your doctor before receiving.
Liver
Consult your doctorFASLODEX 250MG INJECTION is not recommended for use in patients with serious liver problems and can be used with caution in patients with mild to moderate liver problems. Consult your doctor before receiving.
Allergy
Use with CautionDo not receive FASLODEX 250MG INJECTION if you are allergic to Fulvestrant or any of the other ingredients of the medicine.
Use In Pediatrics
ContraindicatedFASLODEX 250MG INJECTION is not recommended for use in children and adolescents (below the age of 18 years). Consult your doctor for advice.
Use In Geriatrics
Use with CautionFASLODEX 250MG INJECTION should be used with caution in elder patients. Consult your doctor for advice.
Others
Before receiving FASLODEX 250MG INJECTION, inform your doctor if you:
- Have previous problems with blood clots or bleeding disorders
- Have osteoporosis (loss of bone density)
Interactions
A. Drug-Drug interactions:
Before receiving FASLODEX 250MG INJECTION, inform your doctor if you are taking any of the following medicine:
- Anticoagulants (a medicine used to thin the blood clots) (Ex. warfarin)
Overdosage:
FASLODEX 250MG INJECTION will be administered to you only by a doctor or nurse in a hospital, so it is unlikely to receive an overdose. However, consult your physician or health care professionals if you experience any unusual symptoms.
Synopsis
| Drug | : | Fulvestrant |
| Pharmacological Category | : | Estrogen receptor antagonists |
| Therapeutic Indication | : | Breast cancer |
| Dosage Forms | : | Injection |
More Information
- Keep FASLODEX 250MG INJECTION out of reach of children
- Store at 2 to 8°C
FAQs About FASLODEX 250MG INJECTION
Q: How is FASLODEX 250MG INJECTION administered?
A: FASLODEX 250MG INJECTION will be given to you only by a doctor or nurse as a slow intramuscular administration. The correct dose and duration of FASLODEX 250MG INJECTION will be decided by your doctor depending on your age, body weight, and disease condition.
Q: Does FASLODEX 250MG INJECTION causes tiredness?
A: Tiredness is one of the most common side effects of FASLODEX 250MG INJECTION. However, it does not affect every individual. Consult your doctor immediately if you experience any unusual symptoms that occur after receiving FASLODEX 250MG INJECTION.
Q: Who should avoid administering FASLODEX 250MG INJECTION?
A: FASLODEX 250MG INJECTION is not recommended for patients having severe kidney problems, liver problems, bleeding disorders, osteoporosis, or previous problems with blood clots. Consult your doctor before receiving FASLODEX 250MG INJECTION.
Q: Is it safe to use FASLODEX 250MG INJECTION in pregnancy?
A: FASLODEX 250MG INJECTION is not recommended for use in pregnant women. Consult your doctor before receiving the medicine.
Q: Is there any food restriction before receiving FASLODEX 250MG INJECTION?
A: As such, there is no food restriction. Consult your doctor before receiving FASLODEX 250MG INJECTION.
References
1. Claudine Isaacs, Anton Wellstein, and Anna T. Riegel. Hormones and Related Agents in Therapy of Cancer. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018 Page – 1237-1247.
2. Mark R. Nathan and Peter Schmid. A Review of Fulvestrant in Breast Cancer. Journal of Oncology and Therapy. May 2017 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488136/
3. I. Blancas, C. Olier, V. Conde, J. L. Bayo, C. Herrero, I. Zarcos-Pedrinaci, F. Carabantes, J. M. Baena-Cañada, J. Cruz & M. Ruiz-Borrego. Real-world data of fulvestrant first-line treatment of postmenopausal women with estrogen receptor-positive metastatic breast cancer. Journal of Nature. February 2021 https://www.nature.com/articles/s41598-021-83622-1
4. Katalin Boer. Fulvestrant in advanced breast cancer: evidence date and place in therapy. Journal of Therapeutic advances in medical oncology. June 2017 https://journals.sagepub.com/doi/10.1177/1758834017711097
5. AstraZeneca UK Limited. Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed on 17th May] https://www.medicines.org.uk/emc/files/pil.68.pdf
Author Details
