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ECOSPRIN AV 75/40 Capsule 10's

High Cholesterol
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    Introduction About ECOSPRIN AV 75/40 CAPSULE

    What is Ecosprin AV 75/40?

    ECOSPRIN AV 75/40 Capsule is commonly used to support heart health and manage cholesterol levels, as advised by healthcare professionals. It combines two active agents that help maintain optimal cardiovascular wellness and support circulatory system health. Always use under valid prescription.

    ECOSPRIN AV 75/40 Capsule helps in maintaining blood flow by acting on platelet function. It also assists in cholesterol management by reducing LDL levels.

    ECOSPRIN AV 75/40 is typically taken with food and water, once daily unless otherwise directed. Adhering to prescribed instructions enhances the benefit and minimizes risks.

    Before taking ECOSPRIN AV 75/40, consult a physician before starting, especially if on other medications. Inform your doctor about allergies or existing health conditions.

    The most common side effects of ECOSPRIN AV 75/40 are indigestion, constipation, flatulence, stomach pain, headache, dizziness and nausea. Consult your doctor if any of the above side effects worsen or persists for a longer duration.   

    Key Composition

    • Contains: Aspirin (75 mg) and Atorvastatin (40 mg)
    • Category: Antiplatelet & lipid-lowering agent
    • Pack size: 10 capsules per strip

    Uses Of ECOSPRIN AV 75/40 CAPSULE

    • Used to support heart health and manage cholesterol levels

    How ECOSPRIN AV 75/40 CAPSULE Works

    1. Composition & Mechanism

    • Aspirin: Helps in maintaining blood flow by acting on platelet function
    • Atorvastatin: Assists in cholesterol management by reducing LDL levels

    The combined mechanism for cardiovascular health support in ECOSPRIN AV 75/40 is based on the synergistic action of two active ingredients: Atorvastatin and Aspirin.

    • Atorvastatin is a statin that works by inhibiting the enzyme HMG-CoA reductase, reducing the production of cholesterol in the liver. This leads to lower levels of “bad” LDL cholesterol and triglycerides, while increasing “good” HDL cholesterol, thereby helping to maintain open, flexible blood vessels and reduce atherosclerotic plaque buildup
    • Aspirin, in its low-dose form, acts as an antiplatelet agent. It inhibits the cyclooxygenase (COX) enzyme, which lowers the production of thromboxane, a substance that promotes platelet aggregation (clot formation). By reducing platelet clumping, aspirin improves blood flow, decreases the risk of clots, and further protects against arterial blockages that can cause heart attacks or strokes.

    How to use ECOSPRIN AV 75/40 CAPSULE

    1. Dosage and Administration Guidelines for ECOSPRIN AV 75/40 Capsule

    Dosage and duration should follow healthcare provider recommendations. ECOSPRIN AV 75/40 is typically taken with food and water, once daily unless otherwise directed. Adhering to prescribed instructions enhances the benefit and minimizes risks.

    What if I forgot to take ECOSPRIN AV 75/40 CAPSULE

    • If a dose of ECOSPRIN AV 75/40 Capsule is missed, take it as soon as you remember
    • However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing routine
    • Do not take two doses at once to make up for the missed dose, as this can increase the risk of side effects
    • Keeping a consistent schedule for your medication is important for best results.

    Overdose

    In case of an overdose, symptoms may include nausea, vomiting, dizziness, headache, ringing in the ears (tinnitus), and stomach upset. Some individuals might experience more severe effects such as increased risk of bleeding or muscle pain and weakness. Overdose can also lead to liver problems, so timely medical evaluation is critical.

    Side Effects Of ECOSPRIN AV 75/40 CAPSULE

    Common Side Effects of ECOSPRIN AV 75/40

    • indigestion
    • constipation
    • flatulence
    • stomach pain
    • headache
    • dizziness
    • nausea

    When to consult a doctor?

    • stomach pain, dark urine or severe muscle pain or cramps especially if accompanied by fever and malaise  

    Warning & Precautions

    Pregnancy

    Contraindicated

    ECOSPRIN AV 75/40 is not recommended during pregnancy as it contains atorvastatin, which is classified as a Category X medication for pregnancy due to a risk of harm to the fetus. Consult your doctor before taking this medicine.

    Breastfeeding

    Contraindicated

    Taking ECOSPRIN AV 75/40 during breastfeeding is considered unsafe. Limited clinical data suggests the components may pass into breast milk and potentially cause harm to the infant. Consult your doctor before taking this medicine.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any heavy tools or machines if you feel dizzy after taking ECOSPRIN AV 75/40

    Kidney

    Use with Caution

    ECOSPRIN AV 75/40 should be used with caution and under medical supervision.

    Liver

    Consult your doctor

    ECOSPRIN AV 75/40 is strictly not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other minor liver problems.

    Allergy

    Contraindicated

    Do not use ECOSPRIN AV 75/40 if you are allergic to Aspirin, Atorvastatin or any other ingredients of this medicine.

    Heart Disease

    Use with Caution

    ECOSPRIN AV 75/40 should be used with caution in patients with heart diseases.

    Use In Pediatrics

    Contraindicated

    ECOSPRIN AV 75/40 Capsule is not recommended for use in children and its safety and effectiveness in patients under 18 years have not been established.  

    Use In Geriatrics

    Use with Caution

    For elderly patients, ECOSPRIN AV 75/40 Capsule can be used but with caution. Consult your doctor before taking this medicine.

    Other Warnings for ECOSPRIN AV 75/40 CAPSULE

    Before taking ECOSPRIN AV 75/40, inform your doctor if you have:

    • stomach ulcers
    • bleeding problems
    • diabetes
    • family history of muscle disorders
    • are scheduled for any upcoming surgery

    Safety Advice

    • Take With Food: Take ECOSPRIN AV 75/40 Capsule with food to minimize stomach upset and reduce gastrointestinal side effects
    • Consistent Routine: Take the capsule at the same time each day for best effectiveness and to build a habit
    • Regular Monitoring: Attend all scheduled doctor visits and blood tests, as regular monitoring of liver, kidney function, cholesterol, and glucose levels is important, especially in elderly patients and those with pre-existing conditions
    • Watch for Side Effects: Report any unusual bleeding, dark urine, persistent muscle pain, yellowing skin/eyes, or severe stomach pain to your healthcare provider.
    • Inform physician: Tell all healthcare professionals (including dentists and surgeons) that you are taking this medication before any procedure.
    • Avoid Self-Adjustment: Do not stop or change your dose without consulting your doctor, as abrupt discontinuation can increase health risks
    • Medication Interactions: Avoid certain over-the-counter painkillers and check with a pharmacist or doctor before starting new medications to avoid interactions

    Diet and Lifestyle Advice

    • Balanced Diet: Incorporate a heart-friendly diet low in saturated fat and cholesterol and rich in vegetables, fruits, whole grains, and omega-3 fatty acids. Limit processed and fried foods for optimal cholesterol management.
    • Alcohol: Avoid or strictly limit alcohol consumption, as alcohol can increase the risk of stomach bleeding when used with ECOSPRIN AV 75/40.
    • Physical Activity: Engage in regular physical activity, such as brisk walking, cycling, or swimming, as recommended by healthcare providers. Exercise can further support cardiovascular health.
    • Smoking: If you smoke, seek support to stop, as smoking elevates cardiovascular risk and may reduce the benefits of your medication.
    • Hydration: Maintain adequate hydration, especially if experiencing side effects like indigestion.

    Drug - Drug interaction

    Interacting Class

    Interaction Description

    Risk/Advice

    Blood Thinners (Warfarin, Heparin)

    Increased risk of bleeding

    Avoid or monitor closely

    Other Antiplatelets (Clopidogrel)

    Additive effect, higher bleeding risk

    Use only under strict medical advice

    Painkillers (NSAIDs: Ibuprofen)

    Increased gastrointestinal bleeding

    Avoid simultaneous use

    Antibiotics (Clarithromycin)

    Increased muscle damage (rhabdomyolysis risk with statins)

    Avoid or adjust statin dosage

    Antifungals (Itraconazole)

    Increased blood levels of statin, risk of muscle injury

    Avoid or reduce statin dose

    Immunosuppressants (Cyclosporine)

    Higher risk of muscle side effects (statin induced)

    Avoid combination

    Niacin (Vitamin B3)

    Increased risk of muscle-related side effects with statins

    Use with caution

    Hepatitis C drugs (Glecaprevir/Pibrentasvir)

    Severe interactions, increased side effects

    Do not combine

    Heart/BP Meds (Amlodipine, Digoxin, Ramipril, Lisinopril)

    May increase side effects or alter effect of either drug

    Monitor by doctor

    Ezetimibe (lipid-lowering)

    Enhanced cholesterol reduction, but higher muscle risk

    Monitor muscles, use under advice

    Antacids

    May interact with statin absorption

    Take medications at different times

    Drug - Food interaction

    • Grapefruit and Grapefruit Juice: Grapefruit products can interfere with the metabolism of atorvastatin by slowing its breakdown in the liver. This may lead to increased blood levels of atorvastatin, raising the risk of side effects such as muscle pain or rare muscle breakdown (rhabdomyolysis). It is generally advised to avoid or limit grapefruit intake while taking this medication and consult with your healthcare provider for specific guidance

    Synopsis

    Drug

    Aspirin, Atorvastatin

    Pharmacological Category

    Non-selective cyclooxygenase (COX) inhibitor, Statins

    Therapeutic Indication

    Support heart health and manage cholesterol levels,

    Dosage Forms

    Tablet, Capsule

    More Information

    Safety Information

    • Consult a physician before starting, especially if on other medications
    • Inform your doctor about allergies or existing health conditions

    FAQs About ECOSPRIN AV 75/40 CAPSULE

    Q: How should ECOSPRIN AV 75/40 be stored?

    A: Store in a sealed pack, away from moisture and heat, as per label guidance.

    Q: Can I take this capsule with other heart medicines?

    A: Always inform the prescribing doctor about all ongoing medicines to ensure compatibility.

    Q: What is ECOSPRIN AV 75/40 CAPSULE used for?

    A: ECOSPRIN AV 75/40 is a lipid lowering medicine. It contains Aspirin and Atorvastatin as the key ingredients. It is used to manage elevated blood cholesterol levels in the body. It can also be used to manage other conditions associated with high cholesterol levels such as blood clots, atherosclerosis, heart attack, stroke or peripheral vascular disease.

    Q: What are the side effects of ECOSPRIN AV 75/40 CAPSULE?

    A: The common side effects of taking ECOSPRIN AV 75/40 CAPSULE are indigestion, constipation, flatulence, stomach pain, headache, dizziness or nausea. Consult your doctor if any of these side effect worsens. You must also inform your doctor if you experience stomach pain, dark urine or severe muscle pain or cramps especially if accompanied by fever and malaise after taking ECOSPRIN AV 75/40 CAPSULE.

    Q: Can I stop taking ECOSPRIN AV 75/40 CAPSULE once my symptoms subside?

    A: No. Do not stop taking ECOSPRIN AV 75/40 CAPSULE without consulting your doctor. As high blood cholesterol levels and blood clot problems are chronic conditions, long term management is necessary to control its symptoms. Therefore, take ECOSPRIN AV 75/40 CAPSULE as advised by your doctor for the stipulated duration. Discontinuation of therapy may cause the symptoms to reappear.

    Q: What should I do if I forget to take a dose of ECOSPRIN AV 75/40 CAPSULE?

    A:If you forget to take a dose of ECOSPRIN AV 75/40 CAPSULE, take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose of ECOSPRIN AV 75/40 CAPSULE and take the next one at the regular time. Do not take a double dose to compensate the missed dose.

    Q: Is ECOSPRIN AV 75/40 CAPSULE a blood thinner?

    A: Yes. ECOSPRIN AV 75/40 CAPSULE is a lipid lowering medicine with blood thinning properties. Aspirin manages the clumping of platelets in the blood vessels and atorvastatin reduces the levels of bad cholesterol (LDL) and triglycerides in the body. Collectively they cause blood thinning and reduces the chances of blood clots in the body.

    Q: What precautions do I need to follow while taking ECOSPRIN AV 75/40 CAPSULE?

    A: Before taking ECOSPRIN AV 75/40 CAPSULE inform your doctor if you have any kidney or heart problems. You must also inform your doctor if you have serious liver problems, stomach ulcers, bleeding problems, diabetes, family history of muscle disorders or if you are scheduled for any upcoming surgery. Consult your doctor before taking ECOSPRIN AV 75/40 CAPSULE if you are pregnant, planning to become pregnant or are breastfeeding. Regularly visit your doctor for checkups and perform all the necessary lab tests recommended for you. ECOSPRIN AV 75/40 CAPSULE may make you bleed more easily even after minor cuts or injuries and so avoid engaging yourself in activities that can injure you easily. Inform your doctor if you experience any unpleasant symptoms (such as stomach pain, dark urine or severe muscle pain or cramps with fever and malaise) after taking ECOSPRIN AV 75/40 CAPSULE.

    Q: Can the use of ECOSPRIN AV 75/40 CAPSULE affect the liver?

    A: Yes. ECOSPRIN AV 75/40 CAPSULE may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it is strictly not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other minor liver problems.

    Q: Should I stop taking ECOSPRIN AV 75/40 CAPSULE before any surgery?

    A: Yes. ECOSPRIN AV 75/40 CAPSULE is a blood thinner which may make you bleed more easily even after minor cuts or injuries. As surgeries are always associated with increased bleeding tendency, simultaneous use of ECOSPRIN AV 75/40 CAPSULE is not recommended as it may make you bleed more.

    Q: Which medicines should I avoid while taking ECOSPRIN AV 75/40 CAPSULE?

    A: While undergoing therapy with ECOSPRIN AV 75/40 CAPSULE, avoid concomitant use of antibiotics (erythromycin), antifungals (ketoconazole) and antiviral medicines (ritonavir) without consulting your doctor. Also, before taking other blood thinning medications (such as warfarin and heparin), you must consult your doctor as a precaution.

    References

    1. KD Tripathi MD. Autacoids and related drugs. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 195-199.

    2. Nikunj Satani, Xu Zhang, Kaavya Giridhar, Natalia Wewior, Chunyan Cai, Jaroslaw Aronowski, Sean I Savitz. A Combination of Atorvastatin and Aspirin Enhances the Pro-Regenerative Interactions of Marrow Stromal Cells and Stroke-Derived Monocytes In Vitro. [Reviewed on April 20, 2021] [Accessed on September 07, 2025]

    3. SUN PHARMA UK LIMITED. Electronic Medicines Compendium (EMC). [Revised on October 2024] [Accessed on September 07, 2025]

    4. Dexcel. Ltd. Electronic Medicines Compendium (EMC). [Revised on April 2025] [Accessed on September 07, 2025]

    Useful Diagnostic Tests

    Author Details

    Written By Dr. Janet.C - Pharm.D
    Reviewed For Accuracy By Dr. Venkatesh Poludasu - MBBS
    Last updated on 11 Sep 2025 | 04:44 PM(IST)
    Lab updated