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Introduction About EBAST 20MG TABLET
EBAST 20MG TABLET contains Ebastine, which belongs to the group of medicines called Antihistamines. It is used in adults and children above 12 years of age for the management of seasonal and persistent allergic rhinitis (runny nose), with or without allergic conjunctivitis (inflammation of the eye). It is also used for the management of itching and urticaria (hives) in adults over the age of 18 years.
Seasonal and perennial allergic rhinitis is an inflammatory condition of the nose that occurs when exposed to allergens. Symptoms include nasal congestion, sneezing, itching, or a runny nose.
EBAST 20MG TABLET should be used with caution in patients with severe liver disease, abnormal heart rhythm disorders, and low potassium levels in the blood. Contact your doctor before taking it.
EBAST 20MG TABLET should be used during pregnancy only if it is considered necessary, and it is not recommended for use in breastfeeding women. Consult your doctor before taking this medicine.
EBAST 20MG TABLET is not recommended for use in children below 12 years of age. It is also not recommended for the management of urticaria (hives) in patients under the age of 18 years. Consult your doctor before taking it.
The most common side effects of taking EBAST 20MG TABLET are headache, drowsiness, and dry mouth. Consult your doctor if any of these symptoms get worse.
Uses Of EBAST 20MG TABLET
- Manage seasonal and persistent allergic rhinitis with or without allergic conjunctivitis in adults and children above 12 years of age
- Manage itching and urticaria (hives) in adults over the age of 18 years
How EBAST 20MG TABLET Works
EBAST 20MG TABLET works by blocking the effect of histamine (a chemical messenger), which is responsible for allergic reactions in the body, thereby providing relief from allergic symptoms such as sneezing, runny noses, watery eyes, and itchy skin rashes.
How to use EBAST 20MG TABLET
Take EBAST 20MG TABLET as advised by your physician. It can be taken with or without meals.
For Tablet: Swallow EBAST 20MG TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse EBAST 20MG TABLET in the specified quantity of water as mentioned on the label. Consume the mixture immediately after reconstitution.
For Oral Disintegrating Tablet, Mouth Dissolving Tablet: Place EBAST 20MG TABLET inside your mouth and allow it to dissolve completely. Do not swallow or chew the medicine.
Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Side Effects Of EBAST 20MG TABLET
Common
- headache
- drowsiness
- dry mouth
Uncommon
- sore throat (pharyngitis)
- runny nose (rhinitis)
- nose bleeds
Rare
- nervousness, insomnia
- altered sensation such as pins and needles (hypoesthesia), altered taste (dysgeusia)
- palpitations, fast pulse
- abdominal pain, nausea, indigestion, vomiting
- inflammation of the liver
- problems with the elimination of bile causing itchiness and yellowing of the skin and eyes
- rash, nettle rash, inflammation of the skin
- menstrual disorders
- oedema (accumulation of water in the tissues)
- weakness (asthenia), dizziness
Stop taking EBAST 20MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- serious allergic reaction such as swelling of the face, tongue, or throat, which may cause difficulty in swallowing or breathing
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling drowsy. Do not consume alcohol, as it can aggravate your drowsiness. Contact your doctor if the drowsiness does not improve.
Dry Mouth
Try to drink plenty of cold water. Sip on cold, unsweetened drinks and use lip balm if your lips are dry. Try to brush your teeth twice a day and use mouthwash. Consult your doctor if the dry mouth gets worse.
Headache
Rest and relax. Drink plenty of fluids, such as water or ORS (Oral Rehydrating Solution) and apply a pain-relieving balm on the head if necessary. Contact your doctor if the headache does not improve.
Warning & Precautions
Pregnancy
Monitoring requiredEBAST 20MG TABLET should be used during pregnancy only if it is considered necessary. Consult your doctor before taking EBAST 20MG TABLET.
Breastfeeding
ContraindicatedEBAST 20MG TABLET is not recommended for use in breastfeeding women as it is not known whether this medicine passes into breast milk. Consult your doctor before taking EBAST 20MG TABLET.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel sleepiness, dizziness, tiredness, and fainting after taking EBAST 20MG TABLET.
Kidney
SafeEBAST 20MG TABLET can be used in patients with impaired kidney function with no dose adjustment. Contact your doctor before taking it.
Liver
Use with CautionEBAST 20MG TABLET can be used in patients with mild to moderate impaired liver function with no dose adjustment. It should be used with caution in patients with severe liver disease. Contact your doctor before taking it.
Allergy
ContraindicatedEBAST 20MG TABLET is not recommended for use if you are allergic to Ebastine or any of the other ingredients of this medicine.
Heart Disease
Use with CautionEBAST 20MG TABLET should be used with caution in patients with certain abnormal heart rhythm disorders, such as prolongation of the QTc interval on the ECG. Consult your doctor before taking EBAST 20MG TABLET.
Use In Pediatrics
ContraindicatedEBAST 20MG TABLET is not recommended for use in children under 12 years of age. It should not be used for the management of urticaria (hives) in patients under the age of 18 years, as safety and efficacy have not been established. Consult your doctor before taking EBAST 20MG TABLET.
Use In Geriatrics
Use with CautionEBAST 20MG TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking it.
Others
EBAST 20MG TABLET is not recommended for use if you have:
- hereditary intolerance to galactose, Lapp lactase deficiency, glucose, and galactose malabsorption
Before taking EBAST 20MG TABLET, inform your doctor if you have:
- intolerance to lactose or other sugars
- phenylketonuria
- low potassium levels in the blood
- skin prick test for allergies
Interactions
A. Drug-Drug Interactions:
Before taking EBAST 20MG TABLET, inform your doctor if you are taking any of the following medicines:
- ketoconazole, itraconazole (medicines used to manage fungal infections)
- erythromycin, clarithromycin, and josamycin (a medicine used to manage bacterial infections)
- rifampicin (used to manage tuberculosis)
Overdosage:
If you or anyone else accidentally takes too much of EBAST 20MG TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Ebastine |
| Pharmacological Category | : | Histamine H1 receptor antagonist |
| Therapeutic Indication | : | Seasonal and perennial allergic rhinitis (runny nose), with or without allergic conjunctivitis and urticaria |
| Dosage Forms | : | Tablet, Dispersible tablet, Oral disintegrating tablet, Mouth-dissolving tablet, Suspension |
More Information
Storage
- Keep the medicine out of reach of children
- Store EBAST 20MG TABLET at room temperature
FAQs About EBAST 20MG TABLET
Q: For what conditions is EBAST 20MG TABLET used?
A: EBAST 20MG TABLET is used in adults and children aged 12 years and older for the management of seasonal and persistent allergic rhinitis (runny nose), with or without allergic conjunctivitis (inflammation of the eye). It is also used for the management of itching and urticaria (hives) in adults over the age of 18 years. Consult your doctor before taking it.
Q: Does EBAST 20MG TABLET cause dry mouth?
A: Yes, EBAST 20MG TABLET can cause dry mouth. For long-term management, good oral hygiene should be maintained (teeth should be cleaned with fluoride toothpaste twice daily) to manage the risk of caries.
Q: Is EBAST 20MG TABLET used for "cold"?
A: Yes, EBAST 20MG TABLET is also used for the management of cold urticaria, dermographic urticaria, atopic asthma, mosquito bites, and the common cold in combination with a medicine called pseudoephedrine. Consult your doctor before taking EBAST 20MG TABLET.
Q: Who should avoid taking EBAST 20MG TABLET?
A: EBAST 20MG TABLET is not recommended for use in patients with an allergic history to Ebastine, galactose intolerance (a condition marked by increased blood glucose levels), Lapp lactose deficiency (a rare hereditary disorder where the body is unable to digest lactose (a sugar found in dairy products), or glucose-galactose malabsorption (a rare hereditary disorder where the body is unable to absorb glucose and galactose). Consult your doctor before taking EBAST 20MG TABLET.
Q: Is EBAST 20MG TABLET safe?
A: Yes, EBAST 20MG TABLET is safe and effective in relieving symptoms of allergic rhinitis and chronic idiopathic urticaria and provides efficacy throughout the 24-hour dosing interval with once-daily administration, and clinical benefit is seen from the first day of management.
Q: What are the side effects of taking EBAST 20MG TABLET?
A: The most common side effects of taking EBAST 20MG TABLET are headache, drowsiness, and dry mouth. Consult your doctor if any of these symptoms get worse.
Q: Can EBAST 20MG TABLET be used during pregnancy?
A: EBAST 20MG TABLET should be used during pregnancy only if it is considered necessary. Consult your doctor before taking EBAST 20MG TABLET.
Q: When to take EBAST 20MG TABLET?
A: Take EBAST 20MG TABLET as advised by your physician. It can be taken with or without meals. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Q: Does EBAST 20MG TABLET make you sleepy?
A: Yes, EBAST 20MG TABLET may cause drowsiness as a common side effect. Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling drowsy. Do not consume alcohol, as it can aggravate your drowsiness. Contact your doctor if the drowsiness does not improve.
Q: Is EBAST 20MG TABLET safe for kids?
A: EBAST 20MG TABLET is not recommended for use in children under 12 years of age. It should not be used for the management of urticaria (hives) in patients under the age of 18 years, as safety and efficacy have not been established. Consult your doctor before taking EBAST 20MG TABLET.
References
1. KD. Tripathi. Histamine and Antihistaminics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page -167.
2. Seoul National University Hospital. The Effect of Ebastine/Pseudoephedrine on Subacute Cough. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in February 2014] [Accessed on 22nd August 2024] https://clinicaltrials.gov/ct2/show/NCT02065440
3. L. R. Wiseman, D. Faulds. Ebastine. A review of its pharmacological properties and clinical efficacy in the treatment of allergic disorders. National Institute of Health NLM, National Centre for Biotechnology Information. PubMed.gov. February 1996. [Accessed on 22nd August 2024] https://pubmed.ncbi.nlm.nih.gov/8808167/
4. Giorgio Ciprandi. Clinical utility and patient adherence with ebastine for allergic rhinitis. National Institute of Health NLM, National Centre for Biotechnology Information. PubMed Central. 2010 [Accessed on 22nd August 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003605/
5. S Rohatagi, M Gillen, M Aubeneau, C Jan, B Pandit, B K Jensen, G Rhodes. Effect of age and gender on the pharmacokinetics of ebastine after single and repeated dosing in healthy subjects. National Institute of Health NLM, National Centre for Biotechnology Information. PubMed.gov. March 2001. [Accessed on 22nd August 2024] https://pubmed.ncbi.nlm.nih.gov/11396753/
6. Ebastine. [Revised in November 2020] [Accessed on 22nd August 2024] https://docetp.mpa.se/LMF/Ebastine%20Generics%20orodispersible%20tablet%20ENG%20PL_09001bee807a05ec.pdf
7. STADA Arzneimittel AG. Ebastine. [Revised in June 2021] [Accessed on 22nd August 2024] https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h115466_piluk.pdf
8. Industrias Farmacéuticas Almirall, S.A. Ebastine. [Revised in June 2021] [Accessed on 22nd August 2024] https://www.ravimiregister.ee/en/Data/PIL_ENG/PIL_10430_ENG.pdf
9. Industrias Farmacéuticas Almirall, S.A. Ebastine. [Revised in May 2019] [Accessed on 22nd August 2024] https://medicarcp.com/website/pdf/pils/484%20-%20en.pdf
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Total IGE
- Wheeze/Rhinitis Comprehensive Panel Adult
- Basic Allergy Package
- Absolute Eosinophil Count, Blood
- Allergy Comprehensive Profile
- Allergy Post Screening Profile
- Eczema Comprehensive Panel
- Jaanch Mens Skin Care Checkup
- Jaanch Women Skin Care Checkup
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