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Introduction About DOLTEUS 1.5MG TABLET
DOLTEUS 1.5MG TABLET contains Haloperidol which belongs to the group of medicines called Antipsychotics. It is used to manage mental health problems like schizophrenia, bipolar disorder and behavioural problems which affects the person’s ability to think, feel and behave normally.
DOLTEUS 1.5MG TABLET is also used to manage Huntington’s disease (degeneration of nerve cells in the brain) and Tourette’s syndrome (disease involving unwanted sounds or repetitive movements).
Your doctor might want you to take several diagnostic tests before or during your management with DOLTEUS 1.5MG TABLET such as ECG (electrocardiogram) or checking the levels of electrolytes such as magnesium or potassium in your blood.
DOLTEUS 1.5MG TABLET is not recommended in patients having heart disease, Parkinson’s disease, Lewy body dementia, progressive supranuclear palsy, or low potassium levels. Before taking DOLTEUS 1.5MG TABLET, inform your doctor if you have kidney problems, liver problems, thyroid problems, blood disorders, depression, bleeding in the brain, prolactin-dependent tumors, or epilepsy.
DOLTEUS 1.5MG TABLET should be used with caution in pregnant women only if the potential benefit justifies the potential risk to the baby and is not recommended for use in breastfeeding women. Avoid consumption of alcohol during management with DOLTEUS 1.5MG TABLET, as it may have additive side effects and lower the blood pressure.
DOLTEUS 1.5MG TABLET is not recommended for use in children under 3 years of age and should be used with caution in elderly patients. The most common side effects of taking DOLTEUS 1.5MG TABLET are feeling agitated, difficulty sleeping, headache, dizziness, sleepiness, nausea, vomiting or constipation. Contact your doctor if any of the above symptoms worsen or doesn’t improve.
Uses Of DOLTEUS 1.5MG TABLET
Manages mental health problems such as:
- schizophrenia
- bipolar disorder
- behavioural problems
- Huntington’s disease
- Tourette’s syndrome
How DOLTEUS 1.5MG TABLET Works
DOLTEUS 1.5MG TABLET contains Haloperidol which is an antipsychotic that works by blocking certain receptors in the brain called dopamine (D2) receptors. This decreases the levels of dopamine, a nerve chemical. Thus, rebalancing dopamine to improve thinking, mood, and behaviour.
How to use DOLTEUS 1.5MG TABLET
Take DOLTEUS 1.5MG TABLET as advised by your doctor. Swallow the medicine with enough water. Do not crush or chew the medicine. Try to take DOLTEUS 1.5MG TABLET daily at the same time in the evening. Your doctor will decide the correct dose and duration of DOLTEUS 1.5MG TABLET for you depending on your age, body weight, and disease condition.
Side Effects Of DOLTEUS 1.5MG TABLET
Common
- agitation
- difficulty sleeping or sleepiness
- headache
- delusions (a false belief about the things which are not there)
- hallucinations (perception of feeling, seeing, and hearing things that are not there)
- depression
- abnormal muscle tension
- dizziness, including sitting or standing up
- fast or upward eye movements, uncontrollable eye movements
- blurred vision
- low blood pressure
- nausea
- vomiting
- constipation
- dry mouth or increased saliva
- skin rash
- unable to pass urine or completely empty the bladder
- impotence (difficulty in getting and keeping an erection)
- weight gain or loss
- changes in liver function (abdominal pain, nausea, vomiting, dark urine, pale stool, jaundice)
Uncommon
- decreased white blood cells and platelets (fever, bleeding easily)
- confusion
- decreased or loss of libido
- fits (seizures)
- stiff muscles and joints
- muscle spasms, twitching, or contractions
- neck spasm causing the neck to twist on one side
- problems in walking
- shortness of breath
- increased skin sensitivity to sunlight
- itching
- excessive sweating
- changes in the menstrual cycle (periods) (like no periods, or long, heavy, painful periods)
- production of breast milk suddenly, breast pain or discomfort
- high body temperature
- swelling caused by fluid that is build-up in the body
Rare
- difficulty breathing due to narrowed airways
- unable to or difficulty in opening mouth
- high levels of prolactin in the blood (changes in menstrual cycle, infertility, menopausal symptoms)
Stop taking DOLTEUS 1.5MG TABLET and contact your physician immediately if you experience any of the following side effects:
- neuroleptic malignant syndrome (signs include high fever, severe muscle stiffness, confusion, and loss of consciousness)
- heart problems such as irregular heartbeat, abnormally fast heartbeat, extra heartbeats
- extrapyramidal disorder (problems controlling movements of the body or limbs) (signs include movements of the mouth, tongue, jaw, and sometimes limbs, feeling restless or difficulty sitting, increased body movements, slow or reduced body movements, jerking or twisting movements, muscle tremors or stiffness, a shuffling walk, being unable to move, and lack of normal facial expression)
- severe allergic reaction (signs include a swollen face, lips, mouth, tongue, or throat, difficulty swallowing or breathing, and itchy rash (hives))
- blood clots in the veins, especially in the legs that can move to lungs
How To Manage Side Effects
Nausea:
Take DOLTEUS 1.5MG TABLET with or after meals. Stick to simple meals while taking DOLTEUS 1.5MG TABLET. Avoid eating rich or spicy food. Do not take any medication on your own. Ask for your doctor’s advice if the nausea doesn’t improve.
Headache:
Try to take rest and don’t involve yourself in exertive activities. Rest in a quiet and dark room. Apply a pain-relieving balm on your forehead. Ask for your doctor’s advice if the headache doesn’t improve
Vomiting:
Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, oily, or sweet foods. Avoid carbonated drinks. Ask for your doctor’s advice if vomiting doesn’t improve.
Dizziness:
Lie, or sit down immediately when you feel dizzy. If you're feeling severe episodes of spinning(vertigo), lie in a dark and quiet place with your eyes closed. Try to avoid vehicle driving. Discuss with your doctor if the symptom worsens.
Constipation:
Eat plenty of fibre-rich foods such as vegetables, fresh fruits, and cereals and drink plenty of water. Exercise more regularly. Ask for your doctor’s advice if constipation doesn’t improve.
Dry mouth:
Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your physician for advice.
Warning & Precautions
Pregnancy
DOLTEUS 1.5MG TABLET should be used with caution in pregnant women only if the potential benefit outweighs the potential risk to the unborn baby. If DOLTEUS 1.5MG TABLET is taken during third trimester it may cause muscle tremors, stiff or weak muscles, being sleepy or agitated, or problems in breathing or feeding in newborn babies. Consult your doctor before taking DOLTEUS 1.5MG TABLET.
Breastfeeding
DOLTEUS 1.5MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Do not drive or use machinery if you feel sleepy or have reduced alertness after taking DOLTEUS 1.5MG TABLET.
Alcohol
Avoid consumption of alcohol while taking DOLTEUS 1.5MG TABLET as it may make you sleepy, less alert and lower down the blood pressure.
Kidney
DOLTEUS 1.5MG TABLET should be used with caution in patients with kidney diseases. Consult your doctor before taking it.
Liver
DOLTEUS 1.5MG TABLET should be taken with caution in patients with liver diseases. Consult your doctor before taking it.
Allergy
Do not take DOLTEUS 1.5MG TABLET if you are allergic to Haloperidol or any of the other ingredients of this medicine.
Heart Disease
DOLTEUS 1.5MG TABLET is not recommended in patients having heart conditions like prolonged QT interval or any other problem with the heart rhythm, heart failure, or recently had a heart attack. DOLTEUS 1.5MG TABLET should be used with caution in patients having other heart diseases such as slow heartbeat. Consult your doctor before taking DOLTEUS 1.5MG TABLET.
Others
DOLTEUS 1.5MG TABLET is not recommended for use if you have:
- lack of awareness of things around you or unusually slow reactions
- Parkinson’s disease
- Lewy body dementia
- progressive supranuclear palsy (PSP)
- low levels of potassium in the blood which is not being manageed
Before taking DOLTEUS 1.5MG TABLET, inform your doctor if you have:
- thyroid problems
- low blood pressure or dizziness while standing up or sitting
- low levels of magnesium or other electrolytes
- bleeding in the brain or a tendency to have a stroke
- history of blood clots or any of your family member has it
- depression or bipolar disorder
- high levels of prolactin or tumor such as breast cancer
- epilepsy or ever had fits
- lactose intolerance
Use in pediatrics:
DOLTEUS 1.5MG TABLET is not recommended to use in children below 3 years of age. Consult your child’s doctor before giving DOLTEUS 1.5MG TABLET to your child.
Use in geriatrics:
DOLTEUS 1.5MG TABLET should be used with caution in elderly patients. Your doctor may adjust your dose depending on your present condition, age and body weight. Consult your doctor before taking DOLTEUS 1.5MG TABLET.
Interactions
A. Drug-Drug interactions:
Before taking DOLTEUS 1.5MG TABLET, inform your doctor if you are taking any of the following medicine:
- medicines used to manage heart problems (Ex. amiodarone, dofetilide, disopyramide, dronedarone, ibutilide, quinidine, verapamil, guanethidine, methyldopa, bepridil and sotalol)
- medicine used to manage depression (Ex. citalopram and escitalopram), anxiety or induce sleep (Ex. alprazolam or buspirone)
- medicines used to manage psychoses (Ex. levomepromazine, fluphenazine, perphenazine, pimozide, sertindole, prochlorperazine, promazine, thioridazine, trifluoperazine, triflupromazine, fluvoxamine, duloxetine, fluoxetine, paroxetine, nefazodone, sertraline, St John’s Wort (herbal), or venlafaxine and ziprasidone)
- medicine used to manage bacterial infections (Ex. azithromycin, rifampicin, clarithromycin, erythromycin, levofloxacin, moxifloxacin, and telithromycin)
- medicine used to manage fungal infections (Ex. pentamidine, itraconazole, posaconazole or voriconazole)
- halofantrine (used to manage malaria)
- medicine used to manage nausea and vomiting (Ex. dolasetron, chlorpromazine, promethazine)
- medicine used to manage cancer (Ex. toremifene and vandetanib)
- medicine used to manage pain or drug addiction (Ex. methadone)
- medicine used to manage epilepsy (Ex. carbamazepine, phenobarbital, or phenytoin)
- medicine used to help you leave smoking (Ex. bupropion)
- medicine used to manage Cushing’s syndrome (Ex. ketoconazole)
- medicine used to manage human immunodeficiency virus or HIV (Ex. indinavir, ritonavir, or saquinavir)
- medicines used to manage severe allergic reactions (Ex. adrenaline)
- medicines used to manage attention deficit hyperactivity disorder (ADHD) (Ex. methylphenidate), Parkinson’s diseases (Ex. levodopa)
- medicines used as blood thinners (Ex. phenindione)
Overdosage:
If you or anyone else accidentally took more of DOLTEUS 1.5MG TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage are extrapyramidal reactions (problems controlling movements of the body), low blood pressure, and sedation.
Synopsis
| Drug | : | Haloperidol |
| Pharmacological Category | : | Antipsychotic |
| Therapeutic Indication | : | Management of mental health problems |
| Dosage Forms | : | Tablet, Injection, Syrup, Liquid |
More Information
- Keep DOLTEUS 1.5MG TABLET out of reach of children
- Store DOLTEUS 1.5MG TABLET at a temperature, not more than 25°C
FAQs About DOLTEUS 1.5MG TABLET
What if I forget to take a dose of DOLTEUS 1.5MG TABLET?
If you forget a dose of DOLTEUS 1.5MG TABLET, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the next scheduled dose at the prescribed time. Do not double the dose to make up for the missed dose as this may increase the chances of developing side effects.
Can DOLTEUS 1.5MG TABLET cause headaches?
Yes. Headache is one of the most common side effects of taking DOLTEUS 1.5MG TABLET. Keep yourself hydrated by drinking more fluids such as water or electrolytes. If needed apply a pain-relieving balm on the forehead. Avoid consumption of alcohol. If the symptoms do not improve or persist, please consult your doctor for advice.
Is driving a car safe after taking DOLTEUS 1.5MG TABLET?
DOLTEUS 1.5MG TABLET may impair mental and/or physical abilities. Do not drive or operate any machines if you feel sleepy or have reduced alertness taking DOLTEUS 1.5MG TABLET. You can resume doing your activities as soon as you feel normal again.
Is DOLTEUS 1.5MG TABLET safe for use in elderly patients?
DOLTEUS 1.5MG TABLET should be used with caution in elderly patients. Your doctor may adjust your dose depending on your present condition, age and body weight. Some serious side effects have been reported in elderly patients having dementia. Consult your doctor before taking DOLTEUS 1.5MG TABLET.
Can I stop taking DOLTEUS 1.5MG TABLET on my own?
Do not stop taking DOLTEUS 1.5MG TABLET until and unless you are told by your doctor to do so. Stopping management suddenly may cause side effects such as nausea, vomiting, or difficulty in sleep. Ask for your doctor’s advice if you wish to discontinue your management with GBNKEYWORD].
Do I need to undergo any diagnostic tests before or while being managed with DOLTEUS 1.5MG TABLET?
Your doctor might want you to take several diagnostic tests before or during your management with DOLTEUS 1.5MG TABLET such as ECG (electrocardiogram) or checking the levels of electrolytes such as magnesium or potassium in your blood.
References
1. KD. Tripathi. Antipsychotic and Antimanic Drugs. Essentials of medical pharmacology. Eighth edition. 2019. Page – 467
2. Ibrahem Hanafi, Subhi Arafat, Lin Al Zayed, Majd Sukkar, Abdullah Albeirakdar, Dima Krayem, and Adib Essali. Haloperidol (route of administration) for people with schizophrenia. NIH National Library of Medicine National Centre for Biotechnology. Pubmed Central. October 2017. [Accessed on 3rd September 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485536/
3. Sajedur Rahman, Raman Marwaha. NIH National Library of Medicine National Centre for Biotechnology. Statpearls. Haloperidol. [Revised in July 2022]. [Accessed on 3rd September 2022] https://www.ncbi.nlm.nih.gov/books/NBK560892/
4. Keith Kleinman. Haloperidol. Science Direct. [Accessed on 3rd September 2022] https://www.sciencedirect.com/topics/medicine-and-dentistry/haloperidol
5. TEVA Pharmaceutical Work Pvt Ltd. Haloperidol Tablets. [Revised in October 2021]. [Accessed on 3rd September 2022] https://products.tevauk.com/mediafile/id/51800.pdf
6. Mylan Pharmaceuticals Inc. Haloperidol Tablet. Dailymed. [Revised in June 2022]. [Accessed on 3rd September 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c559b0b0-4087-d12a-e718-c18ccb6811e6
7. Crescent Pharma Limited. Haloperidol. My Healthbox. [Revised in July 2019]. [Accessed on 3rd September 2022] https://myhealthbox.eu/en/view/3747434/40b13b5ca124a8b41de0345de1c0f889/leaflet
8. MIMS. Haloperidol. [Accessed on 3rd September 2022] https://www.mims.com/indonesia/drug/info/haloperidol?mtype=generic#disclaimer
9. MIMS. Haldol. [Accessed on 3rd September 2022]. https://www.mims.com/india/drug/info/haldol
Useful Diagnostic Tests
- Electrocardiogram (ECG)
- Serum electrolytes
- EEG (Electroencephalogram)
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