DISTOSIDE 600mg Tablet 4's
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Introduction About DISTOSIDE 600MG TABLET
DISTOSIDE 600MG TABLET contains Praziquantel which belongs to the group of medicines called Anthelmintics. DISTOSIDE 600MG TABLET is used in adults and children (aged above 6-years) to manage Schistosomiasis, which is an acute and chronic parasitic disease caused by various types of blood fluke worms (such as Schistosoma mansoni, Schistosoma haematobium, Schistosoma japonicum, Schistosoma mekongi, Schistosoma intercalatum) generally characterized by symptoms such as fever, chills, cough, and/or muscle aches in affected individuals.
DISTOSIDE 600MG TABLET is not recommended for use in patients allergic to Praziquantel. It is also not recommended for use in patients suffering from ocular cysticercosis (parasitic infestation of eye), epilepsy, and/or other parasitic infections involving central nervous system (such as cysticercosis).
Before taking DISTOSIDE 600MG TABLET, inform your doctor if you suffer from neurocysticercosis (parasitic infection caused by larval cysts of pork tapeworm), and/or have moderate to severe liver disease, kidney problems (such as renal impairment), and heart problems (such as cardiac arrhythmias/cardiac insufficiency).
DISTOSIDE 600MG TABLET should be used with caution in pregnant women only if it is clearly necessary. It is not recommended for use in breastfeeding women as the medicine may pass through milk.
DISTOSIDE 600MG TABLET should be used with caution in children and adolescents (aged 6 to 18 years) and advised to be used with caution in elderly patients (aged 65 years and above) after consulting the doctor.
The most common side effects of taking DISTOSIDE 600MG TABLET are headache, dizziness, abdominal pain, nausea, vomiting, diarrhoea, urticaria (red itchy welts), and/or fatigue. Consult your doctor if any of these symptoms worsens.
Uses Of DISTOSIDE 600MG TABLET
- Manage and prevents Schistosomiasis (parasitic disease caused by various types of blood fluke worms)
How DISTOSIDE 600MG TABLET Works
DISTOSIDE 600MG TABLET works by inducing a specific effect on the permeability of cell membrane which leads to rapid contraction of muscles in worms thus resulting in its paralysis and elimination of disease in affected individuals.
How to use DISTOSIDE 600MG TABLET
Take DISTOSIDE 600MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of DISTOSIDE 600MG TABLET
Common
- headache, dizziness
- abdominal pain, nausea, vomiting, diarrhoea
- urticaria (red itchy welts)
- fatigue
- vertigo (sudden internal/external spinning sensation)
- somnolence (excess sleepiness)
- anorexia (eating disorder)
- muscle pain
- feeling unwell, fever
How To Manage Side Effects
Headache:
If DISTOSIDE 600MG TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking DISTOSIDE 600MG TABLET. If it lasts more than a week or becomes severe, then consult and inform your doctor.
Nausea and vomiting:
Take DISTOSIDE 600MG TABLET with/just after a meal. Stick to simple meals. Avoid eating oil rich/spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, and drink slowly in between meals. Consult your doctor if the condition worsens.
Diarrhoea:
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult and inform your doctor if the symptom worsens.
Warning & Precautions
Pregnancy
DISTOSIDE 600MG TABLET should be used with caution during pregnancy only if it is clearly necessary. Contact your doctor before taking the medicine.
Breastfeeding
DISTOSIDE 600MG TABLET is not recommended for use in breastfeeding women as the medicine may pass through milk. Consult your doctor before taking the medicine.
Driving and Using Machines
Do not drive or operate machines if you experience dizziness, somnolence (excessive sleepiness), and/or seizures after taking DISTOSIDE 600MG TABLET.
Kidney
DISTOSIDE 600MG TABLET should be used with caution in patients with kidney problems such as renal impairment. Consult your doctor before taking DISTOSIDE 600MG TABLET.
Liver
DISTOSIDE 600MG TABLET should be used with caution in patients with moderate to severe liver disease. Consult your doctor before taking DISTOSIDE 600MG TABLET.
Allergy
Do not take DISTOSIDE 600MG TABLET if you are allergic to Praziquantel, and/or any other ingredients of this medicine.
Heart Disease
DISTOSIDE 600MG TABLET should be used with caution in patients with heart problems such as cardiac arrhythmias or cardiac insufficiency. Consult your doctor before taking DISTOSIDE 600MG TABLET.
Others
DISTOSIDE 600MG TABLET is not recommended for use if you:
- suffer from ocular cysticercosis (parasitic infestation of eye)
- have/had epilepsy
- have/had other parasitic infections involving central nervous system (such as cysticercosis)
Before taking DISTOSIDE 600MG TABLET, inform your doctor if you:
- suffer from neurocysticercosis (parasitic infection caused by larval cysts of pork tapeworm)
Use in Paediatrics:
DISTOSIDE 600MG TABLET is recommended to be used in children and adolescents (aged 6 to 18 years) to manage/prevent the disease. Consult your doctor before administering the medicine to the child.
Use in Geriatrics:
DISTOSIDE 600MG TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking DISTOSIDE 600MG TABLET.
Interactions
A. Drug-Drug interactions:
Before taking DISTOSIDE 600MG TABLET, inform your doctor if you are taking any of the following medicine:
- rifampicin (medicine used for tuberculosis)
- antiepileptic medicines (used to manage epilepsy) Ex. carbamazepine, phenytoin, phenobarbital
- dexamethasone (medicine used to manage inflammation)
- cimetidine (medicine used to manage ulcers of stomach and intestines)
- ketoconazole, itraconazole (medicine used to manage fungal infections)
- erythromycin (used to manage bacterial infections)
- chloroquine (used to manage malaria)
B. Drug-Food interaction:
Avoid consumption of grapefruit juice while taking DISTOSIDE 600MG TABLET as it may alter the effect of the medicine.
Overdosage:
If you or anyone else accidentally takes too much of DISTOSIDE 600MG TABLET, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.
Synopsis
| Drug | : | Praziquantel |
| Pharmacological Category | : | Antihelmentics |
| Therapeutic Indication | : | Schistosomiasis |
| Dosage Forms | : | Tablet |
More Information
- Keep DISTOSIDE 600MG TABLET out of the sight and reach of children
- Do not store DISTOSIDE 600MG TABLET above 30°C
FAQs About DISTOSIDE 600MG TABLET
Q. What is DISTOSIDE 600MG TABLET used for?
A. DISTOSIDE 600MG TABLET is used in adults and children (aged above 6-years) to manage Schistosomiasis, which is an acute and chronic parasitic disease caused by various types of blood fluke worms (such as Schistosoma mansoni, Schistosoma haematobium, Schistosoma japonicum, Schistosoma mekongi, Schistosoma intercalatum) generally characterized by symptoms such as fever, chills, cough, and/or muscle aches in affected individuals.
Q. What are the side effects of DISTOSIDE 600MG TABLET?
A. The most common side effects of taking DISTOSIDE 600MG TABLET are headache, dizziness, abdominal pain, nausea, vomiting, diarrhoea, urticaria (red itchy welts), and/or fatigue. Consult your doctor if any of these symptoms worsens.
Q. How DISTOSIDE 600MG TABLET is taken?
A. Take DISTOSIDE 600MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Q. What happens if DISTOSIDE 600MG TABLET is taken more than its required dosage?
A. If you or anyone else accidentally takes too much of DISTOSIDE 600MG TABLET, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.
Q. How DISTOSIDE 600MG TABLET works?
A. DISTOSIDE 600MG TABLET works by inducing a specific effect on the permeability of cell membrane which leads to rapid contraction of muscles in worms thus resulting in its paralysis and elimination of disease in affected individuals.
References
1. K.D. Tripathi. Anthelmintic drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 855.
2. Praziquantel. NIH National Library of Medicine. National Center for Biotechnology Information. August 2022. [Accessed on 6th August 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Praziquantel#section=Metabolism-Metabolites
3. Macleods Pharmaceuticals Limited. Praziquantel. [Revised in April 2020] [Accessed on 6th August 2022] https://extranet.who.int/pqweb/sites/default/files/NT004part4_0.pdf
4. Bayer HealthCare Pharmaceuticals Inc. U.S. Food & Drug Administration (USFDA). [Revised in January 2019] [Accessed on 6th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/018714s018lbl.pdf
Useful Diagnostic Tests
- Microscopic examination of stool/urine
- Blood test
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