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Introduction About DICLOBENZ GEL
DICLOBENZ GEL is a combination of Cyclobenzaprine, Diclofenac, Linseed Oil, Menthol and Methyl Salicylate which belongs to the group of medicines called Muscle relaxants, Non-Steroidal Anti- Inflammatory drugs, Cooling agents and Analgesics. It is used to relieve from the discomfort associated with acute, painful musculoskeletal conditions such as rigidity, tension, stiffness and muscle spasms.
Before using DICLOBENZ GEL tell your doctor if you have any liver, kidney, heart diseases, any allergies, pre-existing diseases, and current health conditions. There are limited information on the use of DICLOBENZ GEL in pregnant and breastfeeding women. Your doctor will decide the right dose depends on your child’s age, body weight and disease condition. Consult your doctor before using DICLOBENZ GEL.
Caution must be exercised while using DICLOBENZ GEL in elderly patients. The most common side effects of using DICLOBENZ GEL are skin rash, redness, itchiness (pruritis), general skin inflammation (eczema) and inflammation of the skin at the site of application that is characterised by swelling, rash, or papules (dermatitis, contact dermatitis). Consult your doctor if any of these symptoms doesn’t improve or worsens.
Uses Of DICLOBENZ GEL
- It is used to relieve from the discomfort associated with acute, painful musculoskeletal conditions such as rigidity, tension, stiffness and muscle spasms
How DICLOBENZ GEL Works
[GBKEYWORD] works by blocking the nerve signals of pain sensation, where Cyclobenzaprine causes muscle relaxation by inhibiting 5-Hydroxytryptophan (5-HT2). Diclofenac and Methyl salicylate works by reducing the effects of prostaglandin (substance produced during injury and inflammation causing pain) thereby blocking the pain signals between the brain and nerve endings. Linseed oil helps to reduce inflammation by inhibiting certain chemical substances and strengthens the blood vessel walls thereby reducing fluid leakage. Menthol provides a cooling effect on the skin by causing blood vessels dilatation and it also increase the penetration the medicine into the skin.
How to use DICLOBENZ GEL
Apply DICLOBENZ GEL as advised by your physician. It is for external use only. Apply a thin layer of the medicine and gently massage DICLOBENZ GEL on the affected area.
Side Effects Of DICLOBENZ GEL
Common
- skin rash, redness, itchiness
- general skin inflammation
- inflammation of the skin at the site of application that is characterised by swelling, rash, or papules (dermatitis, contact dermatitis)
Rare
- extensive skin changes with scaling, redness, and large bubbles (bullous dermatitis)
Stop using DICLOBENZ GEL and inform your doctor immediately if you experience any of the following side effects:
- allergic or hypersensitivity reaction includes skin eruption or rash with redness, difficulty in breathing and swallowing
- wheezing, feeling of chest tightness (asthma)
- signs of angioedema like swelling especially in face, throat, and lips
How To Manage Side Effects
Skin rash Or Itching
Try to avoid hot showers because it may cause skin irritation. Avoid frequent contact and rubbing over the affected area. Use sunscreen and protective clothing when outdoors. If this symptom does not get better, consult your doctor.
Warning & Precautions
Pregnancy
Consult your doctorThere are limited information available on the use of DICLOBENZ GEL in pregnant women. Consult your doctor before using.
Breastfeeding
Consult your doctorThere are limited information available on the use of DICLOBENZ GEL in breastfeeding women. Consult your doctor before using.
Driving and Using Machines
Use with CautionDICLOBENZ GEL does not affect your ability to drive or operate machineries. However, consult your doctor before using.
Allergy
ContraindicatedDo not use DICLOBENZ GEL if you are allergic to Cyclobenzaprine, Diclofenac, Linseed Oil, Menthol, Methyl Salicylate, or any other ingredients of this medicine.
Use In Pediatrics
Consult your doctorYour doctor will decide the right dose depends on your child’s age, body weight and disease condition. Consult your doctor before using DICLOBENZ GEL.
Use In Geriatrics
Use with CautionDICLOBENZ GEL should be used with caution in elderly patients. Your doctor will decide the correct dose and duration of the management with DICLOBENZ GEL depending upon your age, disease condition and body weight. Consult your doctor.
Others
Before using DICLOBENZ GEL, inform your doctor if you have:
- have any open wounds
Interactions
A. Drug-Drug interactions:
Before using DICLOBENZ GEL inform your doctor if you are taking or using any medicines with prescription, non-prescription and herbal supplements.
Overdosage:
In case of accidental ingestion or too much application of DICLOBENZ GEL consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Cyclobenzaprine, Diclofenac, Linseed Oil, Menthol, Methyl Salicylate |
| Pharmacological Category | : | Muscle relaxants, Non-Steroidal Anti- Inflammatory drugs, Cooling agents, Analgesics |
| Therapeutic Indication | : | Pain relief, Muscle spasms |
| Dosage Forms | : | Gel |
More Information
- Keep DICLOBENZ GEL out of reach of children
- Store below 25°C
FAQs About DICLOBENZ GEL
Q: What is DICLOBENZ GEL used for?
A: DICLOBENZ GEL is a combination of Cyclobenzaprine, Diclofenac, Linseed Oil, Menthol, Methyl Salicylate. It is used to relieve from the discomfort associated with acute, painful musculoskeletal conditions such as rigidity, tension, stiffness and muscle spasms.
Q: Do I need to take any precautions while using DICLOBENZ GEL?
A: DICLOBENZ GEL should be applied on healthy skin only and not on the open wounds. Do not apply it over connective tissue or mucous membrane like in mouth. Avoid exposure to sunlight after applying DICLOBENZ GEL.
Q: Can DICLOBENZ GEL be used in pregnant women?
A: There are limited information available on the use of DICLOBENZ GEL in pregnant women. Consult your doctor before using.
Q: What are the side effects of using DICLOBENZ GEL?
A: The common side effects are skin rash, redness, itchiness (pruritis), general skin inflammation (eczema) and inflammation of the skin at the site of application that is characterised by swelling, rash, or papules (dermatitis, contact dermatitis).
Q: Is DICLOBENZ GEL safe for use in elderly patients?
A: DICLOBENZ GEL should be used with caution in elderly patients. Your doctor will decide the correct dose and duration of the management with DICLOBENZ GEL depending upon your age, disease condition and body weight. Consult your doctor.
Q: What should I do in case of accidental contact of DICLOBENZ GEL with eyes?
A: Rinse your eyes thoroughly with water in case of accidental contact of DICLOBENZ GEL with eyes. Contact your doctor if eye irritation or any other discomfort persist.
References
1. KD. Tripathi. Nonsteroidal Anti-inflammatory Drugs. Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Eighth edition. 2019. Page –221, 948.
2. Justyna Kolodziejska and Michal Kolodziejczyk. Diclofenac in the treatment of pain in patients with rheumatic diseases. National Library of Medicine, National center for biotechnology information. PubMed Central. Revised in June 2018. [Accessed 23rd September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052370/
3. J V Pergolizzi Jr, R Taylor Jr, J-A LeQuang, R B Raffa. The role and mechanism of action of menthol in topical analgesic products. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. June 2018. [Accessed 23rd September 2022] https://pubmed.ncbi.nlm.nih.gov/29524352/#:~:text=Results%3A%20Menthol%20is%20a%20selective,nociceptors%20and%20then%20desensitizing%20them
4. Methyl salicylate. NIH National Library of Medicine, National Centre for biotechnology information. PubChem. August 2022. [Accessed 23rd September 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Methyl-salicylate
5. Diclofenac. NIH National Library of Medicine, National center for biotechnology information. Pubchem. August 2022. [Accessed 23rd September 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Diclofenac
6. Cyclobenzaprine. NIH National Library of Medicine, National Centre for biotechnology information. PubChem. August 2022. [Accessed 23rd September 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Cyclobenzaprine
7. Manufacturer Laboratórios Basi – Indústria Farmacêutica, S. Electronic Medicines Compendium (EMC). [Revised in July 2021] [Accessed 23rd September 2022] https://www.medicines.org.uk/emc/files/pil.12073.pdf
8. Novartis Consumer Health, Inc. U.S. Food & Drug Administration. [Revised in July 2009] [Accessed 24th September 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/022122s006lbl.pdf
9. Cyclobenzaprine hydrochloride: Summary Report. [Revised in December 2020] [Accessed 23rd September 2022] https://archive.hshsl.umaryland.edu/bitstream/handle/10713/14942/Cyclobenzaprine%20HCl_Final_2020_12.pdf?sequence=1&isAllowed=
10. Viapharma.com. [Accessed 23rd September 2022] https://www.veapharma.com/flexabenz-gel-cyclobenzaprine--4753530.html
11. Via implex. [Accessed 23rd September 2022] https://m.veapharma.com/flexabenz-gel-cyclobenzaprine--4753530.html
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