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Introduction About DEXONA 0.5MG TABLET
DEXONA 0.5MG TABLET contains Dexamethasone which belongs to the group of medicines called Corticosteroids. It is used to manage problematic conditions of the adrenal glands (such as adrenal insufficiency, congenital adrenal hyperplasia and nonsuppurative thyroiditis)
It can also be used to manage various inflammatory auto-immune disease conditions affecting the bones and joints (Ex. rheumatoid arthritis, ankylosing spondylitis), skin and collagen (Ex. Stevens-Johnson syndrome, psoriasis), eyes (Ex. optic neuritis, uveitis or iritis), respiratory tract (Ex. asthma, pneumonitis, tuberculosis), blood and lymph (Ex. leukaemia, anemia, thrombocytopenia, blood cancer, lymph cancer, sarcoidosis), bowel and gut (Ex. Crohn’s disease and ulcerative colitis), brain (Ex. tuberculous meningitis, cerebral edema associated with brain tumor) and heart (inflammation of heart membranes)
It is also indicated in the management of drug induced hypersensitivity reactions and in other allergic reactions (such as atopic dermatitis, allergic conjunctivitis and allergic rhinitis). It also corrects calcium levels among cancer patients and increases urine output or reduces protein loss via urine among patients having kidney problems (such as nephrotic syndrome).
Before taking DEXONA 0.5MG TABLET inform your doctor if you any liver, kidney or heart problems. You must also inform your doctor if you have diabetes, hypertension, glaucoma, epilepsy, underactive thyroid, muscle problems, osteoporosis, stomach problems, tuberculosis, depression, mania or any other mental problems as a precaution.
DEXONA 0.5MG TABLET is not recommended for use in patients with serious unmanageed fungal or viral infections in the body. Do not take DEXONA 0.5MG TABLET without consulting your doctor if you are pregnant or breastfeeding.
The most common side effects of taking DEXONA 0.5MG TABLET are headache, dizziness, acne, stomach discomfort, slow wound healing, skin thinning, high blood pressure, fluid retention, swelling and weight gain of the body and face, high blood sugar levels, muscle weakness, bone thinning and irregular menstrual periods. Consult your doctor if any of these side effect worsens.
Uses Of DEXONA 0.5MG TABLET
It is used to manage the following disease conditions:
- Adrenal insufficiency and its associated conditions
- Bone and joint problems (Ex. rheumatoid arthritis, ankylosing spondylitis)
- Skin and collagen disorders (Ex. Stevens-Johnson syndrome, psoriasis)
- Eye problems (Ex. optic neuritis, uveitis or iritis)
- Respiratory tract diseases (Ex. asthma, tuberculosis, pneumonitis)
- Blood cancer (leukemia), lymph cancer (lymphoma)
- Anemia (low RBC count in blood), thrombocytopenia (low platelet count in blood)
- Problems of bowel and gut (Ex. Crohn’s disease and ulcerative colitis)
- Brain problems (Ex. tuberculous meningitis)
- Heart inflammation (Ex. endocarditis)
- Drug induced hypersensitivity reactions
- Allergic reactions (such as atopic dermatitis, allergic conjunctivitis and allergic rhinitis)
- High blood calcium levels caused due to cancer management
- Protein loss via urine due to kidney problems
How DEXONA 0.5MG TABLET Works
DEXONA 0.5MG TABLET is a steroid medicine with anti-inflammatory and immune suppressant properties. It boosts your body with sufficient corticosteroid levels (cortisol, aldosterone) during deficient conditions and helps your body to function properly.
It also reduces the release of certain chemicals (prostaglandins) in the body that causes inflammation, pain, irritation and swelling. As a result, it reduces allergic and inflammatory conditions in the body.
How to use DEXONA 0.5MG TABLET
Take DEXONA 0.5MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It must be taken with or just after meals to manage stomach upset.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking DEXONA 0.5MG TABLET without consulting your doctor.
Side Effects Of DEXONA 0.5MG TABLET
Common
- headache, dizziness
- spinning sensation, increased sweating
- acne, skin rash, bruising
- nausea, stomach pain or discomfort, increased appetite
- changes in vision, feeling weak or tired, slow wound healing
- skin thinning
- fits
- difficulty in swallowing, sore throat
- high blood pressure, fluid retention
- swelling and weight gain of the body and face
- high blood sugar levels, with excessive thirst
- muscle weakness and wasting
- bone thinning with an increased risk of fractures
- raised pressure in the eye, cataracts
- irregular or lack of menstrual periods
- increased infections
Rare
Stop taking DEXONA 0.5MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of allergic reaction (such as skin rash, itching, blistering and peeling of the skin, swelling of the face, lips, mouth, throat which may lead to breathing difficulties)
- severe skin rashes with blistering and peeling of skin
- feeling depressed, suicidal thoughts, mania, mood swings
- anxiety, sleeping problems, problems in thinking, confusion, memory loss
- hallucinations, strange thoughts, behavioural changes
- signs of pheochromocytoma crisis (headaches, sweating, palpitations and hypertension)
- signs of adrenal suppression (such as swelling and weight gain around the trunk, excessive hair growth in women, muscle weakness and wasting, irregular or missing periods, stunted growth in children, purple stretch marks on body skin, changes in the levels of protein and calcium in your body)
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Nausea And Vomiting
Take DEXONA 0.5MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.
Warning & Precautions
Pregnancy
ContraindicatedDEXONA 0.5MG TABLET is not recommended for use in pregnant women as it may cause serious harm to the growing baby. Therefore, consult your doctor before taking it.
Breastfeeding
ContraindicatedDEXONA 0.5MG TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk and affect the nursing infant. Therefore, consult your doctor before taking it.
Driving and Using Machines
SafeDEXONA 0.5MG TABLET is unlikely to affect your ability to drive or handle any heavy tools or machines.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking DEXONA 0.5MG TABLET as it may make you feel drowsier.
Kidney
Use with CautionDEXONA 0.5MG TABLET should be used with caution in patients with kidney diseases. Therefore, consult your doctor before taking it.
Liver
Use with CautionDEXONA 0.5MG TABLET should be used with caution in patients with liver diseases. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take DEXONA 0.5MG TABLET if you are allergic to Dexamethasone.
Heart Disease
Use with CautionDEXONA 0.5MG TABLET should be used with caution in patients with heart problems (such as recent heart attack or heart failure). Therefore, consult your doctor before taking it.
Others
DEXONA 0.5MG TABLET is not recommended for use if you:
- have any serious unmanageed fungal or viral infections in the body
- are about to get vaccinated (live-virus vaccine)
- currently have or previously had depression, bipolar disorder or any other mental illnesses
- have a family history of mental problems
Before taking DEXONA 0.5MG TABLET, inform your doctor if you:
- have diabetes or a family history of diabetes
- have fits
- have or have a family history of glaucoma
- have viral or fungal infections of the eyes
- have hypertension (high blood pressure)
- have underactive thyroid gland (hypothyroidism)
- have malaria affecting the brain
- have or had been in contact with someone who has chickenpox, measles or shingles
- have any muscle problems (Ex. myasthenia gravis)
- have osteoporosis (brittle bones)
- have pheochromocytoma (a rare tumor of the adrenal glands)
- have stomach ulcer or other serious stomach or intestinal problems
- have or had tuberculosis
- have symptoms of tumour lysis syndrome (such as muscle cramping, muscle weakness, confusion, visual loss or disturbances and shortness of breath)
- are scheduled for any upcoming surgery (including dental surgery)
Use in Pediatrics:
DEXONA 0.5MG TABLET should be used in children and adolescents (aged below 18 years) only if prescribed by the physician. Therefore, consult your doctor for advice before taking it.
Use in Geriatrics:
DEXONA 0.5MG TABLET should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.
Interactions
A. Drug - Drug interactions:
Before taking DEXONA 0.5MG TABLET, inform your doctor if you are taking any of the following medicines such as:
- aminoglutethimide or cyclophosphamide (used for managing cancer)
- anticoagulants (used for blood thinning) such as acenocoumarol, phenindione and warfarin
- medicines used to manage bacterial infections (Ex. isoniazid, erythromycin, clarithromycin and troleandomycin)
- medicines used to manage diabetes (Ex. metformin, glipizide)
- non-steroidal anti-inflammatory medicines (used for fever and pain relief) such as aspirin, ibuprofen
- medicines used to manage epilepsy (such as carbamazepine, phenytoin and primidone)
- ephedrine (used for cough)
- medicines used to manage HIV infections such as ritonavir, cobicistat
- medicines used to manage fungal infection (such as ketoconazole, amphotericin B, itraconazole)
- diuretics (used to manage edema and hypertension) Ex. furosemide, chlorothiazide, hydrochlorothiazide
- rifampicin and rifabutin (used to manage tuberculosis)
- medicines used to reduce anxiety and to induce sleep (such as phenobarbital, pentobarbital)
- thalidomide (a medicine used to manage skin problems and muscle problems)
Overdosage:
If you or anyone else accidentally took more DEXONA 0.5MG TABLET, consult your doctor immediately or visit the nearby hospital straight away.
Synopsis
| Drug | : | Dexamethasone |
| Pharmacological Category | : | Topical Corticosteroids |
| Therapeutic Indication | : | Adrenal insufficiency, Auto Immune Disease, Allergic reactions, Proteinuria |
| Dosage Forms | : | Tablet, Injection, Eye drops, Eye/Ear Drops |
More Information
- Keep DEXONA 0.5MG TABLET out of reach of children
- Store DEXONA 0.5MG TABLET at room temperature
FAQs About DEXONA 0.5MG TABLET
Q: What is DEXONA 0.5MG TABLET used for?
A: DEXONA 0.5MG TABLET is used to manage autoimmune and inflammatory conditions. It is used in adrenal insufficiency, drug induced hypersensitivity reactions, allergic reactions and various inflammatory auto-immune disease conditions affecting the skin, collagen, bones and joints, brain, gut, eyes. It also helps in increasing urine output and manages protein loss via urine among patients having kidney problems.
Q: Is DEXONA 0.5MG TABLET a steroid?
A: Yes. DEXONA 0.5MG TABLET is corticosteroid medicine used to manage problems of adrenal gland and various allergic, hypersensitivity and inflammatory autoimmune disease conditions.
Q: What are the most common side effects of DEXONA 0.5MG TABLET?
A: The most common side effects of taking DEXONA 0.5MG TABLET are headache, dizziness, acne, stomach discomfort, slow wound healing, skin thinning, high blood pressure, fluid retention, swelling and weight gain of the body and face, high blood sugar levels, muscle weakness, bone thinning and irregular menstrual periods. Consult your doctor if any of these side effect worsens or persists for a longer duration.
Q: Does DEXONA 0.5MG TABLET feel high?
A: Yes. DEXONA 0.5MG TABLET may feel high. Such symptoms may disappear once the therapy has been stopped. However, consult your doctor if it bothers you.
Q: How long will it take for DEXONA 0.5MG TABLET to control the disease?
A: The time taken by DEXONA 0.5MG TABLET to control the disease may vary from person-to-person depending upon the dose of dexamethasone and disease severity.
Q: Is DEXONA 0.5MG TABLET safe to use in diabetic patients?
A: DEXONA 0.5MG TABLET may alter the blood sugar levels in the body. Therefore, it is necessary to inform your doctor if you have diabetes before taking DEXONA 0.5MG TABLET as a precaution.
Q: Who should not take DEXONA 0.5MG TABLET?
A: DEXONA 0.5MG TABLET is not recommended for use in patients with serious viral fungal infections. It is also not suitable for use in patients having mental illnesses or a family history of the same.
Q: Can I stop taking DEXONA 0.5MG TABLET once by pain reduces?
A: Take DEXONA 0.5MG TABLET for the stipulated duration recommended by your doctor to achieve maximum results. Do not stop taking DEXONA 0.5MG TABLET or reduce the dose without consulting your doctor, as sudden cessation of the therapy may lead to unpleasant withdrawal symptoms such as skin itchiness, fever, headache, muscle pain, joint pain, runny nose, tiredness or weight loss, especially if you are taking higher dose of dexamethasone.
Q: What to do if I forgot to take a dose of DEXONA 0.5MG TABLET?
A: If you forgot to take a dose of DEXONA 0.5MG TABLET, take it as soon as you remember. However, if it is time for the next dose of DEXONA 0.5MG TABLET skip the missed dose and take the next one regularly. Do not take a double dose to compensate the missed dose.
Q: Can DEXONA 0.5MG TABLET be used in pregnant women?
A: DEXONA 0.5MG TABLET is not recommended for use in pregnant women as it may cause serious harm to the growing baby. Therefore, consult your doctor before taking it.
References
1. KD. Tripathi. Hormones and Related Drugs. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 289.
2. Donavon B. Johnson; Michael J. Lopez; Brendan Kelley. Dexamethasone. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed central. May 2022. [Accessed on 27th January 2023]. https://www.ncbi.nlm.nih.gov/books/NBK482130/
3. Aspire Pharma Limited. Dexamethasone 500 micrograms Tablets Dexamethasone 2mg Tablets. Electronics Medicines Compendium. [Revised in January 2022]. [Accessed on 27th January 2023]. https://www.medicines.org.uk/emc/files/pil.12995.pdf
4. Dexamethasone. NHS. UK. [Revised in August 2020]. [Accessed on 27th January 2023]. https://www.nhs.uk/medicines/dexamethasone-tablets-and-liquid/
5. Teva UK Limited. Dexamethasone 2mg Tablet. [Revised in June 2022]. [Accessed on 27th January 2023]. https://products.tevauk.com/mediafile/id/52838.pdf
6. Dexamethasone Sodium Phosphate Injection IP Dexamethasone Tablets IP. Dexam. Getwell Oncology Pvt Ltd. [Accessed on 27th January 2023]. https://www.getwelloncology.com/pi/dexamethasone-tablets.pdf
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