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Introduction About DAZTOR 20MG TABLET
DAZTOR 20MG TABLET is a combination of Atorvastatin and Cholecalciferol (or Vitamin D3) which belongs to the group of medicines called Cholesterol lowering agents and Vitamin D respectively. It is used to reduce high blood cholesterol levels (hyperlipidaemia) in patients when diet and lifestyle changes does not result in adequate response.
By reducing blood cholesterol levels, it can also be used to manage the risk of heart attack, stroke, angina and other heart related problems. It can also be used to manage vitamin D3 deficiency and bone disorders (such as osteoporosis) among patients who have both hyperlipidemia and vitamin D3 deficiency.
Along with the management, you must follow a cholesterol-lowering diet, lifestyle changes and regular physical activity as instructed by your doctor to achieve better results. Avoid consuming alcohol or grapefruit juice while taking DAZTOR 20MG TABLET as it may lead to unwanted side effects.
Before taking DAZTOR 20MG TABLET inform your doctor if you have any lung, liver, kidney, or heart problems. You must also inform your doctor if you have diabetes, hypertension, thyroid problems, or a family history of muscle disorders.
Do not take DAZTOR 20MG TABLET if you are pregnant or breastfeeding without consulting your doctor. The most common side effects of taking DAZTOR 20MG TABLET are inflammation of nasal passage, throat pain, joint pain, back pain, constipation, nausea and headache. Consult your doctor if any of these side effect worsens.
Uses Of DAZTOR 20MG TABLET
- Manage hyperlipidemia (high blood cholesterol levels)
- Prevents the risk of heart attack, stroke, angina and other heart problems
- Manage and manages Vitamin D3 deficiency
- Manage and manages bone problems (such as osteoporosis)
How DAZTOR 20MG TABLET Works
DAZTOR 20MG TABLET contains two medicines namely, atorvastatin and cholecalciferol. Atorvastatin is a cholesterol lowering agent. It effectively reduces the levels of bad cholesterol (LDL) and triglycerides in the body by blocking the actions of an enzyme called HMG-CoA reductase that synthesizes cholesterol within the body. It also acts on the liver and improves the body’s ability to remove fat particles from the blood.
Cholecalciferol is a form of Vitamin D. It supplements your body with a sufficient amount of Vitamin D3 which manages vitamin D3 deficiency and its associated bone problems. It also improves the cholesterol-reducing actions of atorvastatin and can reduce the muscle pain and damage caused due to atorvastatin within the body.
How to use DAZTOR 20MG TABLET
Take DAZTOR 20MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. DAZTOR 20MG TABLET can be taken with or without meals.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not stop taking DAZTOR 20MG TABLET without consulting your doctor.
Side Effects Of DAZTOR 20MG TABLET
Common
- inflammation of the nasal passages
- throat pain, nose bleeds
- increase in blood sugar levels
- increase in blood creatine kinase
- headache
- nausea, constipation, indigestion, diarrhoea
- joint pain, muscle pain and back pain
- liver problems
Uncommon
- anorexia (loss of appetite)
- weight gain
- dizziness
- having nightmares, insomnia
- tingling sensation
- decreased sensation to pain or touch
- changes in sense of taste
- loss of memory
- blurring of vision
- ringing in the ears followed by vomiting
- bloating, abdominal pain
- neck pain, muscle fatigue
- fatigue, feeling unwell, weakness, chest pain
- swelling especially in the ankles (oedema)
- raised temperature
- high blood calcium levels
- increased calcium levels in urine
Rare
- visual disturbance
- unexpected bleeding or bruising
- cholestasis (yellowish discoloration of the skin and whites of the eyes)
- tendon injury
Stop taking DAZTOR 20MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions (such as skin rash, blisters in the skin, severe peeling, blistering of the skin and swelling of the skin, mouth, eyes, face, lips, tongue and/or throat with difficulty in breathing or swallowing)
- unexplained muscle pain or weakness, especially if accompanied by fever, weakness, or reddish-brown urine (rhabdomyolysis)
- unexpected bleeding or bruising
- severe skin rash with joint disorders and changes in blood counts (Lupus-like disease syndrome)
How To Manage Side Effects
Nausea and Vomiting:
Take DAZTOR 20MG TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.
Headache:
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume excessive alcohol. Reduce looking into bright light and try to get adequate sleep. Consult your doctor if your headache worsens.
Constipation:
Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.
Warning & Precautions
Pregnancy
DAZTOR 20MG TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it. Women of childbearing age must use a reliable contraceptive method to avoid pregnancy while undergoing therapy with DAZTOR 20MG TABLET. However, if you accidentally become pregnant while taking DAZTOR 20MG TABLET, stop taking it and consult your doctor immediately.
Breastfeeding
DAZTOR 20MG TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
Driving and Using Machines
Do not drive or operate any heavy tools or machines if you feel dizzy or sleepy after taking DAZTOR 20MG TABLET.
Alcohol
Avoid consumption of alcohol while taking DAZTOR 20MG TABLET as it may lead to unwanted side effects.
Kidney
DAZTOR 20MG TABLET is not recommended for use in patients with kidney stones. It should be used with caution in patients with other kidney problems. Therefore, consult your doctor before taking it.
Liver
DAZTOR 20MG TABLET is not recommended for use in patients with severe liver diseases. It should be used with caution in patients with a history of liver problems. Therefore, consult your doctor before taking it.
Allergy
Do not take DAZTOR 20MG TABLET if you are allergic to Atorvastatin or Cholecalciferol.
Lungs
DAZTOR 20MG TABLET should be used with caution in patients with lung diseases (such as severe respiratory failure). Therefore, consult your doctor before taking it.
Heart Disease
DAZTOR 20MG TABLET should be used with caution in patients with high blood pressure. Therefore, consult your doctor before taking it.
Others
DAZTOR 20MG TABLET is not recommended for use if you:
- have hypercalcemia (high blood calcium levels)
- have hypercalciuria (high calcium levels in the urine)
- have increased amount of vitamin D in blood (hypervitaminosis)
Before taking DAZTOR 20MG TABLET, inform your doctor if you:
- have an unexplained muscle pain
- had any muscle problems in the past
- have an improper functioning of thyroid gland
- have a personal or a family history of muscle problems
- are an alcoholic
- have diabetes
- are overweight
- have a previous history of stroke
- have a previous history of bleeding within the brain
- have small holes or pockets in the brain due to previous stroke
- have sarcoidosis (a type of connective tissue disease)
Use in pediatrics:
DAZTOR 20MG TABLET should be used in children and adolescents (aged 12 years or older) only if prescribed by the physician. Your doctor will decide the correct dose of DAZTOR 20MG TABLET depending on your child’s age, body weight and health condition.
Use in geriatrics:
DAZTOR 20MG TABLET should be used with caution in elderly patients (aged 70 years or older). Therefore, consult your doctor for advice before taking it.
Interactions
A. Drug-Drug interactions:
Before taking DAZTOR 20MG TABLET, inform your doctor if you are taking any of the following medicines such as:
- medicines used to manage graft rejection (Ex. cyclosporine)
- medicines used to manage bacterial infection (such as fusidic acid, erythromycin, clarithromycin, telithromycin)
- medicines used to manage fungal infection (such as ketoconazole, itraconazole, voriconazole, fluconazole, posaconazole)
- rifampin (a medicine used to manage tuberculosis infection)
- other medicines used to reduce blood cholesterol levels (such as gemfibrozil, fenofibrate, cholestyramine, colestipol or ezetimibe)
- medicines used to manage heart problems (Ex. amlodipine, diltiazem, digoxin, verapamil, amiodarone)
- medicines used to manage viral infections such as HIV or Hepatitis C (Ex. letermovir, ritonavir, lopinavir, atazanavir, indinavir, darunavir, the combination of tipranavir/ritonavir, telaprevir, boceprevir and the combination of elbasvir/grazoprevir, ledipasvir/sofosbuvir)
- warfarin (a medicine used to manage blood clots)
- oral contraceptives (used to manage pregnancy) Ex. levonorgestrel
- medicines used to control epilepsy (such as phenytoin, stiripentol, phenobarbital)
- medicines used to manage stomach ulcers (such as cimetidine)
- antacids (used to neutralize stomach acid and to reduce heartburn) Ex. aluminium hydroxide or magnesium hydroxide
- phenazone (a medicine used for pain relief)
- colchicine (a medicine used to manage gout)
- St. John’s wort (an herbal preparation used to manage depression)
- laxatives (used to manage constipation) such as paraffin oil
- thiazide diuretics (used to remove excess water from the body) such as hydrochlorothiazide
- corticosteroids (used to manage pain and inflammation) such as prednisolone
B. Drug-Food interactions:
Avoid consumption of grapefruit while taking DAZTOR 20MG TABLET as it may lead to unwanted side effects.
Overdosage:
If you or anyone else accidentally took more DAZTOR 20MG TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Atorvastatin, Cholecalciferol |
| Pharmacological Category | : | HMG-CoA reductase inhibitors, Vitamins |
| Therapeutic Indication | : | Hyperlipidaemia |
| Dosage Forms | : | Tablet |
More Information
- Keep DAZTOR 20MG TABLET out of reach of children
- Store DAZTOR 20MG TABLET at room temperature
FAQs About DAZTOR 20MG TABLET
Q: What are the uses of DAZTOR 20MG TABLET?
A: DAZTOR 20MG TABLET is a lipid lowering medicine. It is used to control elevated blood cholesterol levels. By reducing blood cholesterol levels, DAZTOR 20MG TABLET can also manage the risk of heart attack, stroke, angina and other heart problems. It can also be used to manage vitamin D3 deficiency and bone disorders (such as osteoporosis).
Q: Can the use of DAZTOR 20MG TABLET cause diabetes?
A: Yes. DAZTOR 20MG TABLET may increase blood sugar levels in some patients. This is most predominantly seen in patients who already have diabetes along with obesity and/or hypertension. Therefore, consult your doctor before taking this medicine if you are diabetic, obese or have hypertension. Your doctor will closely monitor your blood sugar levels while undergoing therapy with DAZTOR 20MG TABLET to avoid any unwanted side effects.
Q: What is the best time to take DAZTOR 20MG TABLET?
A: Take DAZTOR 20MG TABLET as advised by your physician. Your doctor will decide the best time for you to take DAZTOR 20MG TABLET. Try to take this medicine at the same time each day. It can be taken with or without food.
Q: What are the side effects of taking DAZTOR 20MG TABLET?
A: The most common side effects of taking DAZTOR 20MG TABLET are pain in joints and muscles, gastrointestinal problems such as constipation, diarrhoea, indigestion or nausea and headache. Contact your doctor if any of side effect worsens.
Q: Can I consume alcohol along with DAZTOR 20MG TABLET?
A: DAZTOR 20MG TABLET should be used with caution in patients who consume large amounts of alcohol. Therefore, it is advisable to avoid alcohol consumption while taking this medicine to achieve maximum benefits.
Q: Can the use of DAZTOR 20MG TABLET make me feel more tired?
A: Yes. The use of DAZTOR 20MG TABLET can make you feel more tired, because it acts by reducing the supply of energy to the muscles present in your body. However, you may also feel tired due to other reasons such as severe liver damage. Consult your doctor if you experience excessive tiredness with muscle pain.
Q: Who should not take DAZTOR 20MG TABLET?
A: DAZTOR 20MG TABLET is not recommended for use in patients with severe liver damage. It is also not suitable for use in patients having muscle problems, hypercalcemia and hypercalciuria. If you are pregnant or breastfeeding consult your doctor before taking DAZTOR 20MG TABLET. Before taking DAZTOR 20MG TABLET inform your doctor if you have diabetes or any kidney or heart problems. Do not take this medicine if you are undergoing therapy with antibiotics such as fusidic acid.
Q: What are the dietary restrictions that I need to follow while taking DAZTOR 20MG TABLET?
A: While taking DAZTOR 20MG TABLET, follow a low-cholesterol diet as instructed by your doctor and avoid excessive alcohol intake. Avoid eating oil rich or deep-fried foods. Limit your sugar intake by avoid eating biscuits, cakes, soft drinks, or pastries. Stick to a simple nutritious diet. Avoid consumption of grapefruit while taking DAZTOR 20MG TABLET as it may reduce its effectiveness.
Q: What should I do if I forget to take a dose of DAZTOR 20MG TABLET?
A: If you forget to take a dose of DAZTOR 20MG TABLET, take it as soon as you remember. However, if it is time to take the next dose of DAZTOR 20MG TABLET, skip the missed dose and take the next one at regular times. Do not take a double dose of DAZTOR 20MG TABLET to compensate the missed dose, as it could lead to toxicity.
Q: Can I stop taking DAZTOR 20MG TABLET once my blood cholesterol level is controlled?
A: Do not stop taking this medicine without consulting your doctor, as it could once again increase your blood cholesterol levels. DAZTOR 20MG TABLET can only control your blood cholesterol levels and cannot manage them completely, therefore, it is important to take this medicine until your doctor advises you to stop.
Q: Can I take DAZTOR 20MG TABLET if I am diabetic?
A: DAZTOR 20MG TABLET may increase blood sugar levels in some patients. This is most predominantly seen in patients who already have diabetes along with obesity and/or hypertension. Therefore, consult your doctor before taking DAZTOR 20MG TABLET if you are diabetic, obese or have hypertension.
Q: Does DAZTOR 20MG TABLET cause muscle pain?
A: DAZTOR 20MG TABLET is combination of two medicines namely atorvastatin and cholecalciferol. Cholecalciferol present in this medicine, helps in reducing the muscle pain caused due to atorvastatin. Therefore, this medicine has lower incidence to cause muscle disorders compared to medicines containing plain atorvastatin. However, if you experience unexplained muscle pain or weakness, consult your doctor for advice.
Q: What is DAZTOR 20MG TABLET and what does it do?
A: DAZTOR 20MG TABLET is a lipid lowering medicine used to control elevated blood cholesterol and triglyceride levels. It effectively controls elevated blood cholesterol levels by blocking the action of an enzyme called HMG-CoA reductase which is involved in cholesterol production.
Q: How long should I take DAZTOR 20MG TABLET to manage high cholesterol?
A: You should take DAZTOR 20MG TABLET as long as your doctor advises you to take. Because DAZTOR 20MG TABLET will only help you in managing your cholesterol levels and cannot completely manage them. If you stop using DAZTOR 20MG TABLET, your cholesterol levels may raise once again.
Q: Can DAZTOR 20MG TABLET be taken by pregnant or breast-feeding women?
A: DAZTOR 20MG TABLET is not recommended for use in pregnant or breast-feeding women. Therefore, consult your doctor before taking it. Women of childbearing age must use a reliable contraceptive method to avoid pregnancy while undergoing therapy with this medicine. However, if you accidentally become pregnant while taking this medicine, stop taking it and consult your doctor immediately.
References
1. KD. Tripathi. Drugs Affecting Calcium Balance. Insulin, Hypolipidemic Drugs and Plasma Expanders. Essentials of medical pharmacology. Seventh edition. 2013. Page – 340 & 637.
2. Lindsey A. McIver, Momin S. Siddique. Statpearls. Mechanism of Action of Atorvastatin. National Institute of Health, National Library of Medicine, National center for biotechnology information. Pubmed.gov. September 2021. [Accessed on 7th January 2023] https://www.ncbi.nlm.nih.gov/books/NBK430779/#:~:text=Go%20to%3A-,Mechanism%20of%20Action,cholesterol%20production%20in%20the%20liver
3. José Luis Pérez-Castrillón, Laura Abad Manteca, Gemma Vega, Javier del Pino Montes, Daniel de Luis, and Antonio Duenas Laita. Vitamin D Levels and Lipid Response to Atorvastatin. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. August 2009. [Accessed on 7th January 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779456/
4. Sun Pharmaceutical Industries. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 7th January 2023] https://www.medicines.org.uk/emc/files/pil.4339.pdf
5. Zentiva Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in February 2021] [Accessed on 7th January 2023] https://www.medicines.org.uk/emc/files/pil.11753.pdf
6. Pfizer Ireland Pharmaceuticals. U.S. Food & Drug Administration. [Revised in June 2009] [Accessed on 7th January 2023] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020702s056lbl.pdf
7. Mylan Products Ltd. Desunin 800 IU tablets colecalciferol (vitamin D3). Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed on 7th January 2023] https://www.medicines.org.uk/emc/files/pil.4304.pdf
8. Labialfarma. Cholecalciferol 1000 IU Capsules. Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed on 7th January 2023] https://www.medicines.org.uk/emc/files/pil.7247.pdf
9. Torrent Pharmaceuticals Ltd. MODLIP-D (Atorvastatin and Vitamin D3 tablets). [Revised in October 2015] [Accessed on 7th January 2023] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2595.pdf
Useful Diagnostic Tests
- CBC
- Lipid Profile
- Liver Function Test
- Echocardiography
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