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Introduction About CYCLOFEZ EYE DROPS
CYCLOFEZ EYE DROPS contains Cyclopentolate which belongs to the group of medicines called Mydriatic agents. It is used to dilate the pupil of the eye and to paralyse the lens temporarily for performing an eye examination or for preparing the eye for an operation. It is also used to manage uveitis (inflammation of middle layer of the eye tissues) and iritis (inflammation of coloured ring around the pupil of the eye).
CYCLOFEZ EYE DROPS is not recommended for use in patients with glaucoma and paralysis of the intestine. CYCLOFEZ EYE DROPS should be used with caution in patients with heart diseases (such as heart attack, heart failure or angina), enlarged prostate in men, history of ataxia and inflamed or red eyes. CYCLOFEZ EYE DROPS is not recommended for use in pregnant and breastfeeding women, unless advised by your doctor.
CYCLOFEZ EYE DROPS is not recommended for use in new-born babies (less than 28 days old) unless recommended by the doctor and in children with brain damage, particularly if they may have fits and it is not recommended for use in elderly patients with high pressure inside the eye.
The most common side effects of using CYCLOFEZ EYE DROPS are eye irritation, stinging sensation, fever, confusion, facial flushing, decreased movement of the gastrointestinal tract or slower transit of food and constipation. Consult your doctor if any of the side effect gets worsen or bothers you.
Uses Of CYCLOFEZ EYE DROPS
- Dilates the pupil of the eye and to paralyse the lens temporarily (for performing an eye examination or for preparing the eye for an operation)
- Manage certain types of eye inflammation (uveitis and iritis)
How CYCLOFEZ EYE DROPS Works
CYCLOFEZ EYE DROPS works by blocking the action of acetylcholine to produce relaxation of the sphincter muscle of the iris resulting in dilation of the pupil (mydriasis) and manages the eye from accommodating for near vision (cycloplegia). Therefore, helpful in performing eye examination or eye operation.
How to use CYCLOFEZ EYE DROPS
Use CYCLOFEZ EYE DROPS as advised by your physician. It is for ophthalmic use only. Wash your hands before and after application. Tilt your head slightly backwards and instil a few drops of the medicine into the affected eye. Your doctor will decide the correct dose and duration for you depending upon your age and severity of the condition.
Side Effects Of CYCLOFEZ EYE DROPS
Common
- eye irritation, stinging sensation
- fever
- confusion
- facial flushing
- decreased movement of the gastrointestinal tract or slower transit of food
- constipation
Rare
- allergic reaction
Stop using CYCLOFEZ EYE DROPS and contact your physician immediately if you experience any of the following side effects:
- abnormal heart rate
- difficulty in passing urine (urinary retention)
- hallucinations, mental disturbances
- symptoms of severe allergic reaction/anaphylactic shock (such as severe skin rash, swelling of the face, lips, throat or tongue causing difficulty breathing or swallowing)
- seizures or fits, difficult speaking or speaking in a nonsensible way (in infant or children)
- loss of consciousness affecting breathing, heart rate and blood pressure (in infant or children)
How To Manage Side Effects
Constipation
Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly (such as daily walk). Consult your doctor if the symptom does not improve.
Skin rash Or Itching
Avoid hot showers as it can irritate the skin further. Do not scratch the affected area. Use sunscreen and protective clothing when going outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area after consulting the doctor. If the symptom does not improve consult your doctor.
Warning & Precautions
Pregnancy
Monitoring requiredCYCLOFEZ EYE DROPS is not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before using CYCLOFEZ EYE DROPS.
Breastfeeding
Monitoring requiredCYCLOFEZ EYE DROPS is not recommended for use in breastfeeding women unless considered clearly necessary. Consult your doctor before using CYCLOFEZ EYE DROPS.
Driving and Using Machines
Use with CautionCYCLOFEZ EYE DROPS may cause sensitivity to light, difficulty in focusing and blurred vision therefore, do not drive or operate any machines while using CYCLOFEZ EYE DROPS.
Allergy
ContraindicatedDo not use CYCLOFEZ EYE DROPS if you are allergic to cyclopentolate or benzalkonium chloride or to any other ingredients of this medicine. Inform your doctor if you are sensitive to belladonna alkaloids (drugs such as atropine) before using CYCLOFEZ EYE DROPS.
Heart Disease
Use with CautionCYCLOFEZ EYE DROPS should be used with caution in patients with heart disease (such as heart attack, heart failure or angina). Consult your doctor before using CYCLOFEZ EYE DROPS.
Use In Pediatrics
Monitoring requiredCYCLOFEZ EYE DROPS is not recommended for use in new-born babies (less than 28 days old) unless recommended by the doctor and in children with brain damage, particularly if they may have fits. Consult doctor before administering CYCLOFEZ EYE DROPS to your child.
Use In Geriatrics
ContraindicatedCYCLOFEZ EYE DROPS is not recommended for use in elderly patients with high pressure inside the eye. Consult your doctor before using CYCLOFEZ EYE DROPS.
Others
CYCLOFEZ EYE DROPS is not recommended for use if you:
- have closed-angle glaucoma (elevated pressure inside the eye)
- have bowel paralysis (loss of movement in the intestine)
- wear soft contact lenses
Before using CYCLOFEZ EYE DROPS, inform your doctor if you have:
- enlarged prostate
- down’s syndrome (condition with an extra chromosome in the body)
- history of ataxia (condition that causes coordination problems and unsteadiness)
- inflamed or red eyes
Interactions
A. Drug-Drug interactions:
Before using CYCLOFEZ EYE DROPS, inform your doctor if you are using or taking any of the following medicines:
- ophthalmic cholinesterase inhibitors Ex. physostigmine, pilocarpine, carbachol (medicines used for glaucoma)
- antihistamines such as fexofenadine, cetirizine (used to manage allergy symptoms)
- amantadine (medicine used for parkinson’s disease and influenza A infection)
- anti-psychotics (used to manage schizophrenia and bipolar disorder) such as butyrophenones (Ex. haloperidol) and phenothiazine (Ex. chlorpromazine, fluphenazine)
- tricyclic anti-depressants (used to manage depression) such as amitriptyline, lofepramine and trimipramine
Overdosage:
If you or anyone else accidentally use too much of CYCLOFEZ EYE DROPS, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are increased intraocular pressure, reduced GI motility, decreased salivary, sweat glands, bronchial, pharynx, and nasal secretions, behavioural disturbances, high fever, increased heart rate, high blood pressure, vasodilation and urinary retention.
Synopsis
| Drug | : | Cyclopentolate |
| Pharmacological Category | : | Mydriatics |
| Therapeutic Indication | : | Dilates the pupil and paralyse the lens temporarily, Manages certain types of eye inflammation (uveitis and iritis) |
| Dosage Forms | : | Eye drops |
More Information
- Keep CYCLOFEZ EYE DROPS out of reach of children
- Store below 25°C
FAQs About CYCLOFEZ EYE DROPS
Q: What is CYCLOFEZ EYE DROPS used for?
A: CYCLOFEZ EYE DROPS is used to dilate the pupil of the eye and to paralyse the lens temporarily for performing an eye examination or for preparing the eye for an operation. It is also used to manage uveitis (inflammation of middle layer of the eye tissues) and iritis (inflammation of coloured ring around the pupil of the eye).
Q: Can I use CYCLOFEZ EYE DROPS during pregnancy?
A: CYCLOFEZ EYE DROPS is not recommended for use in pregnant women unless clearly advised by your doctor. Consult your doctor before using CYCLOFEZ EYE DROPS if you are pregnant or planning to get pregnant.
Q: Can CYCLOFEZ EYE DROPS be used in children?
A: CYCLOFEZ EYE DROPS is not recommended for use in new-born babies (less than 28 days old) unless recommended by the doctor and in children with brain damage, particularly if they may have fits. Consult doctor before administering CYCLOFEZ EYE DROPS to your child.
Q: How does CYCLOFEZ EYE DROPS work?
A: CYCLOFEZ EYE DROPS works by blocking the action of acetylcholine to produce relaxation of the sphincter muscle of the iris resulting in dilation of the pupil (mydriasis) and manages the eye from accommodating for near vision (cycloplegia). Therefore, helpful in performing eye examination or eye operation.
Q: Can I wear contact lenses while using CYCLOFEZ EYE DROPS?
A: No, remove the contact lens before instilling CYCLOFEZ EYE DROPS into the eye and re-insert after 15 minutes of using the medicine, as it may cause discolouration of the lenses. Consult your doctor before using CYCLOFEZ EYE DROPS.
References
1. KD. Tripathi. Drugs acting on ANS. Essentials of medical pharmacology. Seventh edition. 2013. Page – 118.
2. Laurence L. Brunton, John S. Lazo, Keith L. Parker. Ocular Pharmacology. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. Page- 1724.
3. Johns Hopkins University. Optimal Method for Mydriasis in Cataract Surgery. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in September 2019] [Accessed on 1st August 2022] https://clinicaltrials.gov/ct2/show/NCT02909140
4. Kalpana Babu and Padmamalini Mahendrada. Medical Management of Uveitis – Current Trends. NIH National Library of Medicine, National center for biotechnology information. PMC Pubmed Central. June 2013. [Accessed on 1st August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744780/
5. Holopack Verpackungstechnik GmbH. Health Products Regulatory Authority (HPRA). [Revised in March 2022] [Accessed on 1st August 2022] https://www.hpra.ie/img/uploaded/swedocuments/11d99839-c800-49fc-91a0-750d5788e318.pdf
6. Holopack Verpackungstechnik GmbH. Electronic Medicines Compendium (EMC). [Revised in June 2020] [Accessed on 1st August 2022] https://www.medicines.org.uk/emc/files/pil.1724.pdf
7. Laboratoire Chauvin. Health Products Regulatory Authority (HPRA). [Revised in June 2022] [Accessed on 1st August 2022] https://www.hpra.ie/img/uploaded/swedocuments/129246b2-08ee-417f-bdf7-860712764776.pdf
8. Bausch and Lomb Incorporated. Cyclopentolate. [Revised in June 2021] [Accessed on 1st August 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=ad85b220-6003-4a78-b900-5195ceaf0fd5
Useful Diagnostic Tests
- Tonometric examination
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