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Introduction About CORTEL TRIO TABLET
CORTEL TRIO TABLET is a combination medication specifically designed to manage hypertension (high blood pressure) when a single therapy is insufficient. By effectively lowering blood pressure, it reduces the risk of severe complications such as heart attack, stroke, and kidney damage.
This medicine combines the benefits of Telmisartan, Amlodipine, and Hydrochlorothiazide, providing a comprehensive solution to manage high blood pressure. It works by relaxing blood vessels, improving blood flow, and increasing urine output (diuretic effect) to help reduce fluid retention, which can contribute to high blood pressure.
Take CORTEL TRIO TABLET with or without food, ideally at the same time every day for maximum effectiveness. As it contains a diuretic (water pill), it may cause increased urination. Avoid taking it within four hours of bedtime to prevent sleep disturbances.
Even if you feel well, continue using this medication as prescribed, as hypertension often shows no symptoms but poses significant health risks if untreated.
Before taking CORTEL TRIO TABLET, inform your doctor if you have liver or kidney problems, are pregnant, or are breastfeeding before starting this medication. Let your doctor know about any other medications you’re taking, especially those for heart conditions or blood pressure.
Regular monitoring of your blood pressure, kidney function, electrolytes, and blood sugar levels is essential to ensure the medicine is working effectively. By consistently taking CORTEL TRIO TABLET and following medical advice, you can manage high blood pressure effectively and reduce the risk of life-threatening complications.
The most common side effects of CORTEL TRIO TABLET includes headache, dizziness, and fatigue, taste changes, diarrhea, and sinusitis, flu-like symptoms and muscle weakness. Stay hydrated to manage side effects like dry mouth, muscle cramps, and excessive thirst. If these symptoms persist or worsen, consult your doctor promptly.
Key Composition
- Amlodipine
- Hydrochlorothiazide
- Telmisartan
Uses Of CORTEL TRIO TABLET
- Hypertension (high blood pressure)
Key Benefits of CORTEL TRIO TABLET for Hypertension:
- Effective Blood Pressure Management: Combines Telmisartan and Amlodipine to lower and maintain blood pressure, reducing strain on the heart.
- Protects Against Heart and Kidney Complications: Helps prevent heart attacks, strokes, and kidney damage caused by uncontrolled hypertension.
- Improves Blood Circulation: Relaxes blood vessels for smoother blood flow, reducing symptoms like dizziness and headaches.
- Convenient Once-Daily Dose: Simplifies hypertension treatment with a single, easy-to-take tablet for better adherence.
How CORTEL TRIO TABLET Works
CORTEL TRIO TABLET helps to manage hypertension. Amlodipine is a calcium channel blocker that relaxes blood vessels by inhibiting the entry of calcium into the muscle cells of the heart and blood vessels. This reduces blood pressure and improves blood flow, making it easier for the heart to pump blood.
Hydrochlorothiazide is a thiazide diuretic that helps the kidneys remove excess salt and water from the body. This reduces fluid buildup, lowers blood pressure, and helps decrease swelling (edema).
Telmisartan is an angiotensin II receptor blocker (ARB) that relaxes blood vessels by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict. This helps lower blood pressure and makes it easier for the heart to circulate blood.
How to use CORTEL TRIO TABLET
How to use CORTEL TRIO TABLET for high blood pressure:
- Take CORTEL TRIO TABLET as advised by your physician.
- Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Dosage and Administration:
- The recommended dosage is determined by your doctor based on your medical condition and response to treatment.
- CORTEL TRIO TABLET can be taken with or without meals.
- Take this medicine at the same time each day to maintain a steady level of medication in your body.
- Avoid Nighttime Doses: As this medicine contains a diuretic, avoid taking it within four hours of bedtime to prevent excessive urination at night.
Missed Dosage instructions for CORTEL TRIO TABLET:
- If you miss a dose, take it as soon as you remember.
- If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule.
- Do not double the dose to make up for a missed one.
Overdosage instructions for CORTEL TRIO TABLET:
- Taking more than the prescribed dose may lead to serious symptoms such as severe dizziness, fainting, or a significant drop in blood pressure.
- In case of suspected overdose, seek immediate medical attention or visit the nearest emergency room.
Doctor’s Advice for Stopping CORTEL TRIO TABLET:
- Stopping this medication suddenly can cause your blood pressure to rise significantly, increasing the risk of heart attack or stroke.
- Always consult your doctor before discontinuing the medication. They may gradually reduce your dose if necessary.
Key Tips for Taking CORTEL TRIO TABLET:
- Stay hydrated to prevent side effects like muscle cramps, dry mouth, or weakness.
- Follow your doctor’s advice on lifestyle changes such as a low-salt diet, regular exercise, and stress management to improve the effectiveness of the medication.
Side Effects Of CORTEL TRIO TABLET
Like all medicines, CORTEL TRIO TABLET may cause certain side effects, although not everybody gets them.
Possible side effects of CORTEL TRIO TABLET are:
- Headache and Dizziness
- Fatigue and Tiredness
- Taste Changes
- Diarrhea and Flu-Like Symptoms
- Sinusitis (Nasal Congestion
- Muscle Weakness and Cramps
- Dry Mouth and Increased Thirst
If any of these side effects persist, worsen, or become bothersome, consult your doctor immediately.
When to Seek Medical Attention for CORTEL TRIO TABLET Side Effects:
Stop taking CORTEL TRIO TABLET and consult your doctor immediately if you experience any of the following side effects:
- Allergic Reactions: Symptoms like rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing.
- Low Blood Pressure (Hypotension): Can cause fainting, extreme dizziness, or lightheadedness, especially after standing up.
- Electrolyte Imbalance: Symptoms include muscle weakness, irregular heartbeat, confusion, or severe dehydration due to excessive urination.
To know more about the adverse reactions for amlodipine+hydrochlorthiazide+telmisartan, refer package insert
How To Manage Side Effects
Dizziness Or Drowsiness
- Rise Slowly: When standing up, do so gradually to prevent sudden drops in blood pressure, which can cause dizziness.
- Avoid Sudden Movements: If you feel dizzy, sit or lie down until the sensation passes.
- Monitor Blood Pressure: Regularly check your blood pressure to ensure it's within a healthy range and discuss any concerns with your doctor.
Dry Mouth
- Stay Hydrated: Drink water frequently to relieve dry mouth and avoid dehydration.
- Use Sugar-Free Lozenges or Gum: These can help stimulate saliva production and keep your mouth moist.
- Avoid Caffeine and Alcohol: These can worsen dry mouth, so it's best to limit their consumption.
Headache
- Stay Hydrated: Drink plenty of water throughout the day to prevent dehydration, which can contribute to headaches.
- Take Over-the-Counter Pain Relievers: Non-prescription pain relief medications can help alleviate mild headaches. However, consult your doctor before use.
- Rest in a Quiet Room: Minimize noise and light to reduce the intensity of your headache.
Warning & Precautions
Pregnancy
Contraindicated- CORTEL TRIO TABLET may not be safe for use during pregnancy. Clinical studies suggest that the components of this medication (such as amlodipine and telmisartan) can be harmful to a developing fetus.
- Telmisartan has been associated with fetal toxicity, and as a result, its use is contraindicated during pregnancy, especially in the second and third trimesters. Therefore, inform your doctor before taking this medicine if you are pregnant or think you may be pregnant.
- Pregnant women should consult their healthcare provider for safer alternatives and personalized advice regarding blood pressure management.
Breastfeeding
ContraindicatedStudies have shown that this medicine can pass through breast milk and its effect on the nursing infant is not well-documented. Therefore, it is not recommended for breastfeeding women?.
Driving and Using Machines
Use with CautionDo not drive or handle heavy tools or machines if you feel dizzy after taking CORTEL TRIO TABLET.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking CORTEL TRIO TABLET as it make you feel dizzier.
Kidney
Consult your doctorCORTEL TRIO TABLET is not recommended for use in patients with severe kidney disease and anuria (low urine output). No dose adjustment is recommended for patients with mild to moderate kidney disease. Consult your doctor before taking it.
Liver
Consult your doctorCORTEL TRIO TABLET is not recommended for use in patients with liver disease. It should be used with caution in patients with mild liver problems. Such patients will be prescribed with a low dose and the dosage will be gradually increased. Therefore, consult your doctor for advice.
Allergy
ContraindicatedDo not take CORTEL TRIO TABLET if you are allergic to amlodipine, hydrochlorothiazide, telmisartan, or any other ingredients in this medicine.
Lungs
Use with CautionCORTEL TRIO TABLET should be used with caution in patients with a history of allergy or bronchial asthma due to increased risk of allergic reaction to the medication.
Heart Disease
Use with CautionCORTEL TRIO TABLET should be used with caution in patients with severe obstructive coronary artery disease due to the increased risk of worsening angina and acute myocardial infarction. It is also used with caution if you have severe congestive heart failure and volume depletion due to the increased risk of developing oliguria, progressive azotemia, or acute renal failure on this medication.
Use In Pediatrics
Consult your doctorCORTEL TRIO TABLET is typically not recommended for use in pediatric patients due to a lack of established safety and efficacy data in children. This medication, which combines amlodipine and telmisartan, is primarily used for managing hypertension in adults. For pediatric use, alternative antihypertensive medications should be considered, and any treatment should be guided by a healthcare professional.
Use In Geriatrics
Use with CautionCORTEL TRIO TABLET should be used with caution in elderly patients. Consult your doctor before taking it.
Others
Before taking CORTEL TRIO TABLET, tell your doctor if you:
- Have diabetes
- Have eye disorders like acute myopia and acute closed-angle glaucoma
- Have systemic lupous erythematosus
- Had sympathectomy
Safety Advice
Expert Advice for Taking CORTEL TRIO TABLET:
- Consistency is Key: Take CORTEL TRIO TABLET at the same time daily to maintain its effectiveness.
- Monitor Blood Pressure: Regularly check your blood pressure to ensure the medication is working properly.
- Avoid Alcohol and Tobacco: Both can lower the effectiveness of the medication and raise blood pressure.
- Hydrate Well: Drink plenty of water to reduce the risk of dizziness and dehydration.
- Balanced Diet: Include potassium-rich foods, low-sodium options, and limit processed food intake.
- Exercise: Regular physical activity helps in blood pressure management and overall heart health.
- Follow-Up Appointments: Regular doctor visits are essential for assessing the effectiveness and adjusting doses.
Interactions
A. Drug-Drug Interactions:
Inform your physician if you are taking any of the following medicines before taking CORTEL TRIO TABLET:
- NSAIDs: Can reduce the blood pressure-lowering effect of CORTEL TRIO TABLET, potentially leading to less control over hypertension.
- Lithium: May increase the risk of lithium toxicity, requiring close monitoring of blood levels.
- Other Antihypertensive Medications: Can enhance blood pressure-lowering effects, increasing the risk of hypotension.
- Potassium Supplements: Risk of hyperkalemia, leading to potentially dangerous heart-related issues.
B. Other Drug-Drug interactions:
- Direct renin inhibitor (Ex. Aliskiren)
- Antimanic (Ex. Lithium)
- Cardiac glycosides (Ex. Digoxin)
- Antidiabetic drugs (Ex. glimepiride, insulin)
- Antihyperlipidemics (Ex. Cholestyramine and Colestipol)
- Phosphodiesterase inhibitors (Ex. Sildenafil)
- Statins (Ex. Simvastatin)
- Immunosuppressants (Ex. cyclosporine or tacrolimus)
C. Drug-food interactions:
- High Potassium Foods: Should be consumed cautiously to prevent excessive potassium levels, which may lead to heart complications.
- Alcohol: Can enhance dizziness and low blood pressure, increasing the risk of fainting.
Synopsis
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Drug |
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Pharmacological Category |
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Angiotensin receptor blockers, Calcium channel blockers, and Diuretics |
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Therapeutic Indication |
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Dosage Forms |
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Tablet |
More Information
Diet and Lifestyle Tips for CORTEL TRIO TABLET Users:
- Limit Salt Intake: Excessive sodium can elevate blood pressure, so aim to keep salt intake low.
- Focus on Whole Foods: Include fresh fruits, vegetables, and whole grains in your daily meals.
- Reduce Processed Foods: Minimize foods high in preservatives, trans fats, and artificial sweeteners.
- Increase Potassium-Rich Foods: Foods like bananas, spinach, and sweet potatoes help balance potassium levels.
- Stay Hydrated: Drink plenty of water to prevent dehydration, which can exacerbate dizziness.
- Exercise Regularly: Aim for at least 30 minutes of moderate activity most days of the week.
- Manage Stress: Practice relaxation techniques such as deep breathing, yoga, or meditation.
- Avoid Smoking and Excessive Alcohol: Both can interfere with the effectiveness of blood pressure medication.
- Monitor Blood Pressure Regularly: Keep track of your readings and share them with your doctor.
- Get Enough Sleep: Aim for 7-8 hours of quality sleep to support overall health.
These tips can complement your treatment and help manage hypertension effectively. Always consult your doctor for personalized advice.
Reviews and Ratings for Amlodipine + Hydrochlorothiazide + Telmisartan:
FAQs About CORTEL TRIO TABLET
Q: What is CORTEL TRIO TABLET used for?
A: CORTEL TRIO TABLET is a combination medication used primarily for managing hypertension (high blood pressure). It contains Amlodipine, Telmisartan and Hydrochlorothiazide. Together, these work by relaxing blood vessels to lower blood pressure, reducing the risk of heart attack, stroke, and kidney damage. CORTEL TRIO TABLET is often prescribed when other single medications for hypertension are insufficient in controlling blood pressure levels. Regular use of this medication helps in improving heart function and managing overall cardiovascular health.
Q: How do I take CORTEL TRIO TABLET?
A: CORTEL TRIO TABLET should be taken exactly as prescribed by your healthcare provider. Typically, it can be taken with or without food, but it’s best to take it at the same time every day for consistency. The usual dosage is one tablet per day, but the dose may vary based on your blood pressure and response to the medication. Do not crush or chew the tablet; swallow it whole with a glass of water.
Q: What are the side effects of CORTEL TRIO TABLET?
A: Common side effects of CORTEL TRIO TABLET include dizziness, headache, fatigue, diarrhea, and muscle cramps. Some individuals may also experience changes in taste or sinusitis. Although rare, more severe side effects like low blood pressure, electrolyte imbalances, or kidney issues can occur. If you experience any of these, or if side effects worsen, contact your healthcare provider. It's essential to stay hydrated while taking this medication to prevent dehydration and associated side effects like dry mouth and extreme thirst.
Q: Can I take CORTEL TRIO TABLET during pregnancy or breastfeeding?
A: CORTEL TRIO TABLET is generally not recommended during pregnancy, especially in the second and third trimesters, as it may harm the developing baby. If you're pregnant or planning to become pregnant, consult your doctor about alternative blood pressure treatments. Breastfeeding mothers should also avoid using Telma-AM H unless specifically advised by a healthcare professional. Both Telmisartan and Hydrochlorothiazide pass into breast milk, and their use could affect the nursing infant. Always seek medical advice before using any medication during pregnancy or breastfeeding.
Q: What should I do if I forgot a dose of CORTEL TRIO TABLET?
A: If you forgot a dose of CORTEL TRIO TABLET, take it as soon as you remember, unless it’s almost time for your next dose. In that case, skip the missed dose—do not take two doses at once. Missing a dose occasionally should not severely affect your treatment, but consistent adherence is key to managing high blood pressure effectively. Set reminders to help you stay on track with your daily dose, and consult your doctor if you have concerns about missed doses or need guidance on how to adjust your medication schedule.
Q: Can CORTEL TRIO TABLET interact with other medications?
A: Yes, CORTEL TRIO TABLET can interact with various medications, including other antihypertensive drugs, NSAIDs (nonsteroidal anti-inflammatory drugs), diuretics, and diabetes medications. Potassium supplements or salt substitutes containing potassium should be used with caution, as they can increase potassium levels when taken with Telma-AM H. Additionally, if you're taking medications for kidney problems, heart issues, or other conditions, it's important to inform your doctor before starting CORTEL TRIO TABLET to avoid harmful drug interactions. Regular monitoring of kidney function and electrolytes may be required during treatment.
Q: What lifestyle changes can help improve the effectiveness of CORTEL TRIO TABLET?
A: To maximize the benefits of CORTEL TRIO TABLET and manage hypertension effectively, it's important to make lifestyle changes alongside medication. Reduce sodium intake by avoiding processed and high-salt foods, and increase potassium-rich foods like bananas and spinach. Regular exercise, managing stress, and maintaining a healthy weight are key factors in controlling blood pressure. Limiting alcohol consumption, quitting smoking, and monitoring your blood pressure regularly also support better health outcomes. These steps complement the medication, helping you better manage hypertension and reduce cardiovascular risks.
Q: Who should not take CORTEL TRIO TABLET?
A: CORTEL TRIO TABLET is not recommended for use in patients with liver disease, severe kidney disease and anuria (low urine output), or allergic to amlodipine, hydrochlorothiazide, and telmisartan. Consult your doctor for advice.
Q: What precautions must be taken while using CORTEL TRIO TABLET?
A: CORTEL TRIO TABLET should be used with caution in patients with a history of allergy or bronchial asthma, severe obstructive coronary artery disease, severe congestive heart failure and volume depletion, or have diabetes, eye disorders like acute myopia and acute closed-angle glaucoma, systemic lupous erythematosus, or a history of sympathectomy.
Q: What are the side effects of CORTEL TRIO TABLET?
A: The most common side effects of taking CORTEL TRIO TABLET are fatigue, influenza-like symptoms, dizziness, nausea, diarrhea, sinusitis and upper respiratory tract infection, and oedema. Consult your doctor if any of the side effects worsen.
Q: What if I forget to take a dose of CORTEL TRIO TABLET?
A: If you miss a dose of CORTEL TRIO TABLET, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Q: Can I stop taking CORTEL TRIO TABLET once my blood pressure is normal?
A: No, even if your blood pressure becomes normal, you should continue taking the medication as prescribed. Stopping it suddenly can cause a rebound increase in blood pressure, leading to serious health risks. Always consult your doctor before stopping this medication.
References
1. Jitsuo Higaki, Issei Komuro, Kosuke Shiki, Ganghyuck Lee, Atsushi Taniguchi, Hiroshi Ikeda, Daisuke Kuroki, Seiichiro Nishimura, and Toshio Ogihara. Effect of hydrochlorothiazide in addition to telmisartan/amlodipine combination for treating hypertensive patients uncontrolled with telmisartan/amlodipine: a randomized, double-blind study. Hypertens Res. 2017. [Accessed on 19th September 2024] click here
2. Sanofi India Limited. Amlodipine, Hydrochlorothiazide, and Telmisartan. [Revised in December 2020] [Accessed on 18th September 2024] click here
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