New Revised MRP, 100% GST benefit passed Clinzucia 600mg Injection 4ml
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INTRODUCTION ABOUT CLINZUCIA 600MG INJECTION
CLINZUCIA 600MG INJECTION contains Clindamycin, which belongs to the group of medicines called Antibiotics. It is used to manage serious bacterial infections in adults and adolescents above 12 years of age. Bacterial infection occurs when bacteria enter the body, increasing in number and causing a reaction in the body. Symptoms include fever, fatigue, headache, nausea, vomiting and swollen lymph nodes in the neck, armpits, groin or elsewhere.
Before receiving CLINZUCIA 600MG INJECTION, inform your doctor if you have or ever had impaired kidney and liver function, gastrointestinal diseases (colon inflammation) or problems with muscle function (Parkinson’s disease, myasthenia gravis). CLINZUCIA 600MG INJECTION should be used with caution in pregnant and breastfeeding women, consult your doctor before receiving.
CLINZUCIA 600MG INJECTION is generally not recommended for use in children below 12 years of age. CLINZUCIA 600MG INJECTION should be used with caution in elderly patients above 60 years of age. The most common side effects of receiving CLINZUCIA 600MG INJECTION are nausea, abdominal pain, vomiting, diarrhea, blood abnormalities and skin rashes. Consult your doctor if your symptoms do not improve.
USES OF CLINZUCIA 600MG INJECTION
- Manage serious bacterial infections in adults and adolescents (over 12 years of age)
HOW CLINZUCIA 600MG INJECTION WORKS
CLINZUCIA 600MG INJECTION acts against the bacteria by binding to the 50S subunit of the bacterial ribosome (site of protein synthesis). Which in turn manages protein synthesis and kills the infection-causing bacteria.
DIRECTIONS FOR USE
CLINZUCIA 600MG INJECTION will be administered to you only by a doctor or a nurse into your vein (intravenous infusion with a drip). Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
SIDE EFFECTS OF CLINZUCIA 600MG INJECTION
COMMON
- Gastrointestinal disorders (nausea, abdominal pain, vomiting, diarrhea)
- Severe or prolonged or bloody diarrhea during or after management may be a sign of bowel inflammation (pseudomembranous colitis)
- Blood abnormalities (changes in the number of white blood cells or reduction in blood platelets (which increases the risk of bleeding or bruising))
- Diseases of the blood vessels such as inflammation of the veins(thrombophlebitis).
- Skin lesions with large blistering skin rash (maculopapular exanthema, morbilliform exanthema), ’nettle rash’ (urticaria)
- The results of liver tests may be affected
UNCOMMON
- Nervous system disturbances, such as an inhibiting nerve impulse progression (neuromuscular blocking effect) and altered taste (dysgeusia)
- Difficulty breathing, low blood pressure
- Pain and abscess at the site of injection
RARE
- Fever
- Itchy skin (pruritus).
- Inflammation of the vaginal mucosa (vaginitis)
- Serious skin reactions:
- Stevens-Johnson syndrome (peeling of large areas of skin, especially around the mouth, nose, eyes, and genitals) and Lyell syndrome (a more serious illness with blistering of the skin)
- Extensive red skin rash with skin flaking (exfoliative dermatitis, bullous dermatitis, erythema multiforme)
- Serious allergic reaction which causes swelling of the face or throat(angioedema)
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Consult your doctor if symptoms do not show improvement.
Nausea And Vomiting
Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if symptoms do not show improvement.
Stomach Pain
Try to rest and relax. Eat and drink slowly or try to have smaller meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.
WARNING & PRECAUTIONS
PREGNANCY
Use with CautionCLINZUCIA 600MG INJECTION should be used with caution in pregnant women or women planning to have a baby. It will be given to you by the doctor only if it's clearly necessary. Consult your doctor before receiving it.
BREASTFEEDING
Use with CautionCLINZUCIA 600MG INJECTION should be used with caution in breastfeeding women as it can pass into breast milk. The breastfed infant can have diarrhea, fungal infections, and hypersensitivity. Consult your doctor before receiving it.
DRIVING AND USING MACHINES
Use with CautionDo not drive or use machines as CLINZUCIA 600MG INJECTION may cause mild to moderate side effects like feeling dizzy, tired or headaches. Consult your doctor for advice.
KIDNEY
Use with CautionCLINZUCIA 600MG INJECTION should be used with caution in patients with impaired kidney problems. Consult your doctor before receiving it.
LIVER
Use with CautionCLINZUCIA 600MG INJECTION should be used with caution in patients with impaired liver problems. Consult your doctor before receiving it.
ALLERGY
ContraindicatedDo not receive CLINZUCIA 600MG INJECTION if you are allergic to Clindamycin or any other ingredients of this medicine.
USE IN PEDIATRICS
ContraindicatedCLINZUCIA 600MG INJECTION is not recommended for use in children below 12 years of age. Consult your doctor before receiving CLINZUCIA 600MG INJECTION.
USE IN GERIATRICS
Use with CautionCLINZUCIA 600MG INJECTION should be used with caution in elderly patients above 60 years of age. consult your doctor before receiving CLINZUCIA 600MG INJECTION.
OTHERS
Before receiving CLINZUCIA 600MG INJECTION, inform your doctor if you:
- Have problems with your muscle functions (Ex. myasthenia gravis (pathological muscular weakness) or Parkinson’s disease (shaking palsy)
- Have previously suffered from gastrointestinal diseases (Ex. inflammation of the colon)
INTERACTIONS
A. Drug-Drug interactions:
Before receiving CLINZUCIA 600MG INJECTION, inform your doctor if you are taking any of the following medicine:
- Warfarin or similar medicines (Ex. acenocoumarol and fluindione) used to thin the blood.
- Muscle relaxants (Ex. cyclobenzaprine)
- Rifampicin (to manage tuberculosis)
- St John's wort (Hypericum perforatum) to manage depression
- Carbamazepine, phenytoin or phenobarbital (to manage epilepsy)
- Enzalutamide (manages prostate cancer), dabrafenib (cancer drug)
- Efavirenz (manages HIV/AIDS)
Overdosage:
CLINZUCIA 600MG INJECTION will be administered to you only by a doctor or a nurse in a hospital, so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.
SYNOPSIS
| Drug | : | Clindamycin |
| Pharmacological Category | : | Lincosamides |
| Therapeutic Indication | : | Serious bacterial infections |
| Dosage Forms | : | Injection, Tablet, Capsule, Gel, Cream, Lotion, Solution, Spray, Soap |
MORE INFORMATION
STORAGE
- Keep CLINZUCIA 600MG INJECTION out of reach of children
- Do not store above 25°C
FAQs ABOUT CLINZUCIA 600MG INJECTION
Q: What is CLINZUCIA 600MG INJECTION used for?
A: CLINZUCIA 600MG INJECTION is used to manage serious bacterial infections in adults and adolescents above 12 years of age. Bacterial infection occurs when bacteria enter the body, increasing in number and causing a reaction in the body. Symptoms include fever, fatigue, headache, nausea, vomiting and swollen lymph nodes in the neck, armpits, groin or elsewhere.
Q: Can I drive while receiving CLINZUCIA 600MG INJECTION?
A: Do not drive or use machines as CLINZUCIA 600MG INJECTION may cause mild to moderate side effects like feeling dizzy, tiredness or headaches. Consult your doctor for advice.
Q: How does CLINZUCIA 600MG INJECTION work?
A: CLINZUCIA 600MG INJECTION acts against the bacteria by binding to the 50S subunit of the bacterial ribosome (site of protein synthesis). Which in turn manages protein synthesis and kills the infection-causing bacteria.
Q: Can CLINZUCIA 600MG INJECTION be used in pregnancy?
A: CLINZUCIA 600MG INJECTION should be used with caution in pregnant women or women planning to have a baby. It will be given to you by the doctor only if it's clearly necessary. Consult your doctor before receiving it.
Q: Can CLINZUCIA 600MG INJECTION be used in children?
A: CLINZUCIA 600MG INJECTION is not recommended for use in children below 12 years of age. Consult your doctor before receiving it for more information on safety measures.
REFERENCES
1. KD Tripathi. Macrolide, Lincosamide, Glycopeptide and Other Anti bacteria IN Antibiotics. Urinary Antiseptics. Essentials of Medical Pharmacology. Eighth Edition. 2019. Page –805-806.
2. Patrick B, Murphy, Karlyle G. Bistas, Jacqueline K.Le. Clindamycin. National Library of medicine, National center for biotechnology information.[Revised in July 2021] [Accessed on 11th May 2022] https://www.ncbi.nlm.nih.gov/books/NBK519574/
3. Manuel Polanco Morales, Anna Paola Thome Carvallo, Karla Adriana Bautista Espinosa,and Edgar Enrique Meza Murillo. A young man with myelosuppression caused by clindamycin: a case report. National Library of medicine, National center for biotechnology information. Pubmed central 2014. [Accessed on 11th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917410/
4. Infomed Fluids Srl. Electronic Medicines Compendium (EMC). [Revised in March 2019] [Accessed on 11th May 2022] https://www.medicines.org.uk/emc/files/pil.11006.pdf
5. Pfizer. Pharmacia & Upjohn Co. U.S Food and Drug Administration. [Revised in October 2013] [Accessed on 11th May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/050441s079,050639s038lbl.pdf
6. Clindamycin. Health direct. [Revised in August 2020] [Accessed on 11th May 2022] https://www.healthdirect.gov.au/bacterial-infections
USEFUL DIAGNOSTIC TESTS
- Complete blood count tests
- Liver function test
- Kidney function test
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