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CILACAR 10 Tablet 15's

Hypertension
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    Introduction About CILACAR 10 TABLET

    What is Cilacar 10 Tablet 15's?

    Cilacar 10 Tablet contains Cilnidipine, a calcium channel blocker used for managing high blood pressure (hypertension). It helps relax blood vessels, ensuring better blood flow and reducing the heart's workload.

    Take Cilacar 10 Tablet exactly as prescribed by your healthcare provider. Swallow the tablet whole with a glass of water, preferably at the same time each day. Avoid crushing or chewing the tablet.

    How Cilacar 10 mg helps improve quality of life?

    Cilacar 10 mg is a calcium channel blocker (CCB) that relaxes and widens blood vessels by inhibiting calcium entry into the smooth muscle cells. This leads to reduced blood pressure, which helps in reducing complications like heart attacks, strokes, and kidney damage.

    With better physical health, reduced stress, and greater energy, patients experience a significant improvement in overall quality of life, including emotional and social aspects.

    The common side effects of Cilacar 10 include dizziness, headache, and flushing. If you experience severe side effects, consult your doctor immediately.

    Uses Of CILACAR 10 TABLET

    • High blood pressure (Hypertension)

    Benefits of CILACAR 10 TABLET

    1. Effectively lowers high blood pressure: Dual Calcium Channel Blocking Action: Cilnidipine blocks two types of calcium channels, which sets it apart from other calcium channel blockers (CCBs):

    • L-Type Calcium Channels: It is found in the smooth muscle of blood vessels, by blocking these channels causes relaxation and dilation of blood vessels, reducing vascular resistance and lowering blood pressure
    • N-Type Calcium Channels: It is located in the sympathetic nerves that control stress responses. Also inhibits and reduces the release of norepinephrine, a neurotransmitter responsible for constricting blood vessels during stress. This helps in controlling stress-induced spikes in blood pressure

    2. Reduces the risk of heart attack and stroke:

    • Cilacar 10 mg is a calcium channel blocker (CCB) that relaxes and widens blood vessels by inhibiting the entry of calcium into the smooth muscle cells of blood vessel walls
    • This action reduces vascular resistance and lowers blood pressure, which is a primary risk factor for heart attacks and strokes
    • By reducing vascular resistance, Cilacar 10 decreases the effort required for the heart to pump blood, improving heart efficiency and reducing the risk of heart attacks

    3. Improves overall cardiovascular health:

    • Uncontrolled hypertension is a major risk factor for heart attacks and strokes. Cilacar 10 helps to maintain stable blood pressure, reducing the likelihood of these life-threatening events
    • It also protects the brain and heart by reducing sudden pressure spikes that can lead to vascular rupture or clots

    How CILACAR 10 TABLET Works

    Cilacar 10 mg Tablet contains Cilnidipine which is a vasodilator, blocks the channels, reducing calcium ions from entering the cells. This results in:

    • Relaxation of vascular smooth muscles
    • Dilation of blood vessels (vasodilation)
    • Reduction in vascular resistance, which leads to a decrease in blood pressure
    • As a result, it relaxes the blood vessels and allows blood to flow more smoothly across the blood vessels with less pressure
    • It also improves blood flow and oxygen supply to the heart muscles which reduces the strain on the heart, improves heart function and manages the risks of heart attack or stroke

    How to use CILACAR 10 TABLET

    Cilacar 10 is a prescription medicine which needs to be taken under medical supervision. Always consult your doctor or pharmacist if you have any questions or concerns about taking this medication.

    Recommended Dosage of Cilacar 10 Tablet:

    • The recommended dosage is one tablet daily or as prescribed by your healthcare provider
    • Always take this medicine as prescribed by your doctor, usually once daily

    How to take Cilacar 10 Tablet?

    • Swallow the Cilacar 10 Tablet whole with water, preferably at the same time each day
    • Cilnidipine can be taken with or without food, but taking it at the same time every day helps maintain steady blood levels
    • Try to take it at the same time each day to maintain consistent control of your blood pressure

    Overdose

    • If you or anyone else accidentally took Cilacar 10, consult your doctor immediately or visit the nearby hospital

    Side Effects Of CILACAR 10 TABLET

    Common Side Effects of Cilacar 10:

    • dizziness
    • headache
    • flushing

    How To Manage Side Effects

    Dizziness Or Drowsiness

    • Avoid Sudden Movements: When transitioning from sitting or lying to standing, do so gradually
    • Rise Slowly: Stand up slowly and hold onto a stable surface, like a chair or wall, until you feel steady
    • Drink Plenty of Fluids: Drink enough water throughout the day to stay hydrated, as this can help maintain blood pressure levels

    Headache

    • Aim for 6-8 cups of water daily, depending on your activity level and climate
    • Avoid Caffeine: Caffeine can sometimes make headaches worse, especially if you drink it excessively
    • Rest in a quiet and dark room can help reduce the intensity. Minimize exposure to bright lights or loud noises, which can worsen the headache
    • Lie Down and Relax: Take short naps or rest to allow your body to recover

    Hot Flushes

    • Apply a cool cloth or ice pack to the face may help soothe flushing
    • Hot beverages and alcohol can trigger or worsen flushing
    • Avoid Sudden Movements: Standing up too quickly can lead to dizziness or an increase in flushing. Stand up slowly to allow your body to adjust and minimize sudden changes in blood flow

    Warning & Precautions

    Pregnancy

    Monitoring required

    Cilacar 10 (Cilnidipine) is classified as a Category C medication for pregnancy, indicating that its safety in pregnant women has not been established. It should only be used during pregnancy if the potential benefit outweighs the risk.

    Breastfeeding

    Consult your doctor

    There is no sufficient data on the excretion of Cilacar 10 (Cilnidipine) in breast milk, and due to potential risks to the infant, it is advised to avoid its use while breastfeeding or consult a healthcare provider for safer alternatives.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any heavy tools or machines if you feel dizzy after taking Cilacar 10.

    Alcohol

    Consult your doctor

    Avoid consumption of alcohol while taking Cilacar 10 as it could make you feel dizzier.

    Kidney

    Use with Caution

    Cilacar 10 should be used with caution in patients with kidney problems. Dosage adjustment and careful monitoring are required in such patients. Therefore, inform your doctor if you have any pre-existing kidney diseases as a precaution.

    Liver

    Use with Caution

    Cilacar 10mg Tablet should be used with caution in patients with liver problems. Regular medical check-ups and blood tests are required in such patients. Therefore, inform your doctor if you have any pre-existing liver diseases as a precaution.

    Allergy

    Contraindicated

    Do not take Cilacar 10 if you are allergic to Cilnidipine or any other ingredients of this medicine.

    Heart Disease

    Consult your doctor

    Cilacar 10 is not recommended for use in patients with severe heart problems such as heart failure or aortic stenosis (narrowing of arteries). It should be used with caution in patients with angina or heart failure. Therefore, consult your doctor before taking it.

    Use In Pediatrics

    Contraindicated

    Safety and efficacy of Cilacar 10 in paediatric patients has not been established. Thus, Cilacar are not recommended in children.

    Use In Geriatrics

    Use with Caution

    Cilacar 10 should be used with caution in elderly patients (aged 65 years or older). Therefore, consult your doctor before taking it.

    Others

    Before taking Cilacar 10, inform your doctor if you have:

    • severe low blood pressure (hypotension)
    • edema (swelling of body parts)

    Safety Advice

    • Inform Your Doctor About All Medications: Provide a complete list of all prescription medications, OTC drugs, herbal supplements, and vitamins
    • Monitor for Drug Interactions: Consult your doctor about past medications while taking Cilacar 10
    • Avoid Grapefruit and Grapefruit Juice: Grapefruit inhibits the metabolism of Cilnidipine via the CYP3A4 enzyme, increasing drug levels in the blood
    • Minimize alcohol intake: Alcohol enhances the blood pressure-lowering effects of Cilacar, potentially causing dizziness or fainting
    • Avoid sudden changes in position: Cilacar can cause dizziness or lightheadedness, especially when standing up quickly

    Diet and Lifestyle Advice

    Healthy Lifestyle Tips for Hypertension:

    1. Dietary Recommendations: Follow a DASH Diet (Dietary Approaches to Stop Hypertension)

    • Foods to Take: fruits, vegetables, whole grain like rice, oats, and quinoa, lean proteins like fish, poultry, low-fat like yogurt, or cheese, healthy fats like nuts and seeds
    • Foods to Avoid: saturated fats (fried foods, fatty cuts of meat), sugary snacks and beverages, processed and high-sodium foods (e.g., canned soups, fast food)
    • Reduce Sodium Intake: Limit daily sodium consumption to less than 2,300 mg (ideally 1,500 mg for those with high blood pressure)
    • Increase Potassium Intake: Include potassium rich foods such as bananas, oranges, spinach, sweet potatoes, and beans
    • Stay Hydrated: Drink plenty of water throughout the day. Limit or avoid alcohol and sugary drinks, as they can interfere with blood pressure management

    2. Exercise and Physical Activity:

    • Do regular physical activity which help to strengthen the heart and helps lower blood pressure

    3. Stress Management:

    • Practice mindfulness meditation or deep breathing exercises
    • Engage in hobbies that bring relaxation and joy
    • Ensure adequate sleep (7–9 hours per night)

    4. Regular Health Monitoring:

    • Check your blood pressure at home regularly using a reliable monitor
    • Keep track of your weight, cholesterol, and blood sugar levels

    Exercise for Heart Health: Cilacar 10 mg in Managing Blood Pressure

    1. Aerobic (Cardio) Exercises: Aerobic activities improve heart efficiency and reduce resting blood pressure by increasing oxygen flow and strengthening the heart muscle

    • Examples: Brisk walking, Jogging or running, Cycling or Swimming
    • Frequency: At least 30 minutes/day, 5 days/week (or 150 minutes/week)

    2. Flexibility and Balance Exercises: While these exercises do not directly impact blood pressure, they reduce stress and improve overall well-being

    • Examples: Stretching routines
    • Frequency: Daily or at least 3–4 times/week

    Activities to avoid while taking “CILACAR 10”

    • Strenuous Physical Activities: Like intense physical exertion can lead to sudden blood pressure fluctuations or exacerbate side effects like dizziness or fainting. Examples: Heavy weightlifting, sprinting or high-intensity interval training (HIIT)

    Activities Requiring Quick Position Changes: Cilacar can cause postural hypotension (a sudden drop in blood pressure when standing up), increasing the risk of dizziness or falls. Examples: Yoga styles with rapid position changes (e.g., Power Yoga), Gymnastics or fast-paced dance routines

    Drug - Drug interaction

    Before taking Cilacar 10, inform your doctor if you are taking any of the following medicines such as:

    1. Other Antihypertensive Drugs: (Blood Pressure Medications)

    • Types of Medications: ACE inhibitors (e.g., Enalapril), ARBs (e.g., Losartan), diuretics (e.g., Furosemide), beta-blockers (e.g., Atenolol), and other calcium channel blockers (e.g., Amlodipine)
    • Effect of Interaction: Cilacar 10 mg lowers blood pressure by dilating blood vessels. When combined with other blood pressure-lowering medications, there is an increased risk of hypotension (low blood pressure), which can cause dizziness, fainting, and other cardiovascular issues. Close monitoring of blood pressure is necessary when combining these medications
    • Management: Your healthcare provider may need to adjust the doses of these medications or monitor you more closely

    2. Blood Thinners (Anticoagulants): Examples: Warfarin, Apixaban, Rivaroxaban

    • Interaction: While there is no direct interaction, Cilacar’s blood pressure-lowering effects can increase the risk of falls or injuries, leading to complications like excessive bleeding in patients on anticoagulants
    • Symptoms: Increased bruising, bleeding gums, or prolonged bleeding
    • Management: Monitor for signs of bleeding and maintain caution to avoid injuries.

    3. Antidiabetic Medication. Examples: Insulin, Sulfonylureas (e.g., Glimepiride), SGLT2 inhibitors (e.g., Empagliflozin)

    • Interaction: Cilacar 10 can enhance the risk of hypoglycemia (low blood sugar) by altering insulin secretion or masking symptoms like sweating and palpitations
    • Symptoms: Dizziness, confusion, excessive fatigue, or shakiness
    • Management: Regularly monitor blood glucose levels and adjust antidiabetic medication doses if necessary

    Drug - Food interaction

    Cilacar 10 and grapefruit interaction:

    • Interaction: Consuming grapefruit or its juice can increase the absorption of Cilnidipine in the body. This heightened absorption may lead to an excessive lowering of blood pressure and an increased risk of side effects
    • Recommendation: Avoid grapefruit and grapefruit juice while taking Cilacar 10 mg

    FAQs About CILACAR 10 TABLET

    Q: What conditions does Cilacar 10 Tablet manage?

    A: Cilacar 10 is used for managing high blood pressure (hypertension).

    Q: Can I take Cilacar 10 with other medications?

    A: Yes. Cilacar 10 can be taken with other medications, but it is important to be aware of potential drug interactions that may affect their effectiveness or cause side effects. Consult your doctor before taking any medications.

    Q: Does Cilacar 10 cause dizziness?

    A: Yes. It may cause dizziness in some individuals. Avoid sudden movements, stand up slowly and hold onto a stable surface, like a chair or wall, until you feel steady

    Q: Is Cilacar 10 safe during pregnancy?

    A: Cilacar 10 (Cilnidipine) is classified as a Category C medication for pregnancy, indicating that its safety in pregnant women has not been established. It should only be used during pregnancy if the potential benefit outweighs the risk.

    Q: Can I take Cilacar 10 with other blood pressure medications?

    A: Yes. Yes, Cilacar 10mg can be taken with other blood pressure medications, but it is important to do so under the guidance of a healthcare provider. Combining medications may enhance blood pressure control but also carries a risk of side effects.

    Q: How does Cilacar 10 work?

    A: Cilacar 10 mg is a calcium channel blocker (CCB) that relaxes and widens blood vessels by inhibiting calcium entry into the smooth muscle cells. This leads to reduced blood pressure, which helps in reducing complications like heart attacks, strokes, and kidney damage.

    Q: Can I stop taking Cilacar 10 abruptly?

    A: Do not stop taking Cilacar without consulting your doctor as your blood pressure may raise once again. Make sure to take the medicine for the stipulated duration recommended by your doctor to achieve maximum results.

    Q: What should I do if I miss a dose of Cilacar 10?

    A: Take Cilacar as soon as you remember, do not double the dose to make up for a missed dose.

    Q: What is the best time to take Cilacar 10 mg?

    A: Cilacar 10 mg can be taken with or without meals. Your doctor will decide the best time for you to take Cilacar 10 mg based on your age, body weight and disease condition.

    Q: Can I consume alcohol while taking Cilacar 10 mg Tablet?

    A: Avoid consumption of alcohol while taking Cilacar 10 mg Tablet as it might make you feel dizzier and drowsier.

    Q: Can Cilacar 10 mg Tablet cause ankle swelling?

    A: Cilacar 10 mg Tablet may cause edema or swelling of ankles in few patients. If you experience ankle swelling, keep your legs on a table or slightly elevated from the ground level. If this symptom bothers you, contact your doctor.

    Q: What are the common side effects of Cilacar 10 mg Tablet?

    A: The common side effects of Cilacar 10 include dizziness, headache, and flushing. If you experience severe side effects, consult your doctor immediately.

    Q: Can the use of Cilacar 10 affect the liver?

    A: Yes. Cilacar 10 may affect the way your liver work. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before taking it.

    References

    1. Lionel H. Opie. Calcium channel blockers. Drugs for the heart. 8th Edition. 2013. Page- 88-89.

    2. Junichi Minami, Yuhei Kawano, Yuriko Makino, Hiroaki Matsuoka and Shuichi Takishita. Effects of cilnidipine, a novel dihydropyridine calcium antagonist, on autonomic function, ambulatory blood pressure and heart rate in patients with essential hypertension. NIH. National Library of Medicine, National Center for biotechnology information. PMC. PubMed Central. September 2016. [Accessed on January 27th, 2025] 

    3. Unique pharmaceutical laboratories. Cilacar 20mg. September 2017. [Accessed on January 27th, 2025] 

    4. Cilnidipine. Centaurpharma.com. [Accessed on January 27th, 2025] 

    5. Cilocab. Cilnidipine. ACL limited. [Accessed on January 27th, 2025] 

    6. Blue cross laboratories. [Revised on April 2021] [Accessed on January 27th, 2025]

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    Author Details

    Written By Dr. Janet.C - Pharm.D
    Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)
    Last updated on 29 Jan 2025 | 12:20 PM(IST)
    Lab updated