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Introduction About CHLORPROMAZINE 100MG TABLET
CHLORPROMAZINE 100MG TABLET contains Chlorpromazine which belongs to the group of medicines called Antipsychotics. It is used to manage the following conditions such as schizophrenia and other psychoses (especially paranoid), mania and hypomania, anxiety psychomotor agitation excitement, violent or dangerously impulsive behaviour, intractable hiccup and nausea, vomiting of terminal illness (where other medicines have failed or are not available). It is also used to manage schizophrenia and autism (in children).
It is not recommended for use in patients with CNS depression, bone marrow depression and Phaeochromocytoma. Consult your doctor for advice before taking the medicine.
Before taking this medicine inform your doctor if you have heart diseases, liver disease or kidney problems, thyroid, epilepsy, and parkinson’s disease.
Pregnant and breastfeeding women should consult their doctors before taking this medicine. Tell your doctor if you will be exposed to extreme heat, or to insecticide poisons while you are taking this medicine.
The most common side effects are drowsiness, dry mouth or stuffy nose, blurred vision, constipation and impotence. Consult your doctor if any of the above side effects gets worse.
Uses Of CHLORPROMAZINE 100MG TABLET
It is used to manage the following conditions:
- schizophrenia and other psychoses (especially paranoid), mania and hypomania
- anxiety psychomotor agitation excitement, violent or dangerously impulsive behaviour
- intractable hiccup
- nausea and vomiting of terminal illness (where other medicines have failed or are not available)
- schizophrenia and autism (in children)
How CHLORPROMAZINE 100MG TABLET Works
CHLORPROMAZINE 100MG TABLET exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby managing the excess of dopamine in the brain.
How to use CHLORPROMAZINE 100MG TABLET
Take CHLORPROMAZINE 100MG TABLET as directed by your physician. Swallow the medicine as a whole with a plenty of water and do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your conditions.
Side Effects Of CHLORPROMAZINE 100MG TABLET
Common
- drowsiness
- dry mouth or stuffy nose
- blurred vision
- constipation
- impotence
Rare
Stop taking and contact your doctor immediately, if you have,
- sudden appearance of sore throat, fever or other signs of infection
- allergic reactions symptoms such as hives, difficult breathing, swelling of your face, lips, tongue, or throat
- uncontrolled muscle movements in your face such as chewing, lip smacking, frowning, tongue movement, blinking or eye movement
- stiffness in your neck, tightness in your throat, trouble breathing or swallowing
- confusion, agitation, feeling jittery, trouble sleeping
- weakness
- breast swelling or discharge
- seizures
- jaundice (yellowing of the skin or eyes)
- low white blood cell counts such as fever, chills, mouth sore, skin sore, sore throat, cough, trouble breathing, feeling light-headed
- severe nervous system reactions such as very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors
How To Manage Side Effects
Dry mouth:
Chew sugar-free gum. Control caffeine intake. Do not use mouthwashes. Sip water regularly.
Constipation:
Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.
Warning & Precautions
Pregnancy
CHLORPROMAZINE 100MG TABLET is not recommended for use in pregnant women. Consult your doctor before taking this medicine.
Breastfeeding
CHLORPROMAZINE 100MG TABLET is not recommended for use in breast feeding women as it may pass into breast milk. Consult your doctor before taking this medicine.
Driving and Using Machines
Do not drive or operate any machines, after taking CHLORPROMAZINE 100MG TABLET since it may reduce the alertness.
Alcohol
Avoid consumption of alcohol while taking this medicine.
Kidney
CHLORPROMAZINE 100MG TABLET should be used with caution in patients suffering from kidney diseases. Consult your doctor before taking this medicine.
Liver
CHLORPROMAZINE 100MG TABLET is not recommended for use in patients with liver failure or active liver disease. Consult your doctor before taking this medicine.
Allergy
Do not take CHLORPROMAZINE 100MG TABLET if you are allergic (hypersensitive) to Chlorpromazine or other ingredients of this medicine.
Lungs
CHLORPROMAZINE 100MG TABLET should be used with caution in patients suffering chronic respiratory disorders. Consult your doctor before taking this medicine.
Heart Disease
CHLORPROMAZINE 100MG TABLET should be used with caution in patients suffering from heart diseases. Consult your doctor before taking this medicine.
Others
CHLORPROMAZINE 100MG TABLET is not recommended if you have:
- CNS depression
- jaundice or blood dyscrasia
- bone marrow depression
- phaeochromocytoma
- epilepsy
- parkinson’s disease
- hypoparathyroidism
- myasthenia gravis
- prostatic hypertrophy
Before taking CHLORPROMAZINE 100MG TABLET inform your doctor if you have:
- glaucoma
- stroke risk factors
- thromboembolism
Use in pediatrics:
CHLORPROMAZINE 100MG TABLET is not recommended for use in children under 1 year of age. Consult your doctor before taking this medicine.
Use in geriatrics:
CHLORPROMAZINE 100MG TABLET should be used with caution in elderly patients. Consult your doctor before taking this medicine.
Interactions
A. Drug-Drug interactions:
Before taking CHLORPROMAZINE 100MG TABLET tell your physician if you are taking any of the following medicine:
- benztropine (used to manage Parkinson’s disease)
- antacids (used to manage ulcers)
- lithium (used as mood stabilizers)
- ciprofloxacin (manages infection)
- fluvoxamine (manages OCD)
- oral contraceptives
- vemurafenib (used to manage cancer)
- oral anticoagulants (used to manage blood clot)
- guanethidine and clonidine
- quinidine, disopyramide, amiodarone and sotalol (manages heart disorders)
- bepridil, cisapride, sultopride, thioridazine, methadone
- intravenous erythromycin, intravenous vincamine
- halofantrine, pentamidine, sparfloxacin
- stimulant laxatives, intravenous amphotericin B
- glucocorticoids and tetracosactides
- other antipsychotic medicines
Overdosage:
If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms of overdose includes dry mouth, bloating or stomach cramps, feeling restlessness, fever, muscle stiffness, jerky muscle movements, changes in heart rate, fainting, or seizure (convulsions).
Synopsis
| Drug | : | Chlorpromazine |
| Pharmacological Category | : | Phenothiazines |
| Therapeutic Indication | : | Schizophrenia, Mania, Anxiety |
| Dosage Forms | : | Tablet, Injection |
More Information
- Keep out of reach of children
- Store at room temperature
FAQs About CHLORPROMAZINE 100MG TABLET
Can I take CHLORPROMAZINE 100MG TABLET during breastfeeding?
No, it is not recommended for use in breast feeding women. Consult your doctor before taking this medicine.
Can CHLORPROMAZINE 100MG TABLET cause constipation?
Yes, this medicine may cause constipation in some individuals. Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.
Is CHLORPROMAZINE 100MG TABLET benzodiazepine/sleeping medicine?
This medicine is not a benzodiazepine. It belongs to a class of medicines called phenothiazine antipsychotics. It should not be used as a sleeping medicine.
What does CHLORPROMAZINE 100MG TABLET do to the brain?
CHLORPROMAZINE 100MG TABLET exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby managing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms.
Does CHLORPROMAZINE 100MG TABLET cause any side effects?
The most common side-effects are feeling drowsy or dizzy, blurred vision and dry mouth. It may cause your skin to become more sensitive to sunlight than normal. Protect your skin from bright sunlight and do not use sunbeds.
References
1. Sukhmanjeet Kaur Mann; Raman Marwaha. Chlorpromazine. National Center for Biotechnology. Information, U.S. National Library of Medicine [Accessed 01 Dec 2021] https://www.ncbi.nlm.nih.gov/books/NBK553079/
2. Drugs.com. Chlorpromazine [Accessed 01 Dec 2021] https://www.drugs.com/mtm/chlorpromazine.html
3. Webmed.com. Chlorpromazine [Accessed 01 Dec 2021] https://www.webmd.com/drugs/2/drug-1444/chlorpromazine-oral/details
4. Sanofi-aventis New zealand limited. [Accessed 04 Feb 2013] [Accessed 01 Dec 2022] https://genesight.com/wp-content/uploads/2017/05/Chlorpromazine-Thorazine-FDA-Label.pdf
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