INTRODUCTION ABOUT CHESTON EXPECTORANT

CHESTON EXPECTORANT is a combination of Bromhexine, Chlorpheniramine maleate and Guaifenesin which belongs to the group of medicines called Mucolytics, Antihistamines and Nasal decongestants. It is used for symptomatic relief of productive cough.

Avoid alcohol consumption while taking CHESTON EXPECTORANT as it may increase drowsiness. CHESTON EXPECTORANT is not recommended for use in patients with severe hypertension, severe coronary artery disease or porphyria. CHESTON EXPECTORANT should be used with caution in patients with asthma, bronchitis, bronchiectasis or chronic lung disorders; severe liver or kidney disease; hypotension; ischaemic heart disease or cardiovascular collapse; fits; diabetes mellitus; a peptic ulcer; and glaucoma.

CHESTON EXPECTORANT is not recommended for use in pregnancy unless considered necessary. CHESTON EXPECTORANT is not recommended for breastfeeding women unless considered necessary, as it may pass through breast milk. In children aged 2 to 12 years, CHESTON EXPECTORANT should be used with caution.CHESTON EXPECTORANT should be used with caution in patients over the age of 65.

The most common side effects of taking CHESTON EXPECTORANT are drowsiness and sedation, change in concentration, incoordination, dizziness, headache, blurred vision, nausea, vomiting, dry mouth and fatigue. If your symptoms worsen, consult your doctor.

USES OF CHESTON EXPECTORANT

For symptomatic relief of productive cough

HOW CHESTON EXPECTORANT WORKS

CHESTON EXPECTORANT is a cough suppressant, whereas Bromhexine is a mucolytic that thins and breaks down phlegm, making it easier to cough up. Chlorpheniramine maleate is an antihistamine that blocks the binding of histamine (responsible for allergic reactions such as sneezing, watery and itchy eyes and a runny nose) to histamine H1 receptors, thus managing allergic reactions. Guaifenesin is an expectorant that relieves chest congestion, making breathing easier by loosening and clearing phlegm from the lungs and making it easier to cough up.

DIRECTIONS FOR USE

Take CHESTON EXPECTORANT as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

SIDE EFFECTS OF CHESTON EXPECTORANT

COMMON

drowsiness and sedation
change in concentration
un-coordination
dizziness, headache
blurred vision
nausea, vomiting, dry mouth, fatigue

UNCOMMON

stomach pain, diarrhoea

RARE

rash, urticaria

Stop taking CHESTON EXPECTORANT and contact your physician immediately if you experience any of the following side effects:

skin rash (including lesions of the mucous membranes such as mouth, throat, nose, eyes and genitals)
serious allergic reactions include an itchy rash, swelling of the face or throat causing wheezing or difficulties in breathing or fainting
skin lesions such as severe blistering or peeling of the skin, mouth, throat, nose, eyes and genitals

HOW TO MANAGE SIDE EFFECTS

Dizziness and drowsiness:

Try to rest and relax. Get enough sleep. Do not drive or operate any machines if you feel dizzy or drowsy. Do not consume alcohol, as it increases dizziness or drowsiness. Contact your doctor if your dizziness or drowsiness does not improve.

Headache:

Rest and relax. Drink plenty of fluids, such as water or electrolytes and apply a pain-relieving balm on the head if necessary. Do not consume alcohol. Contact your doctor if the headache worsens.

Nausea, vomiting:

Eat simple meals. Avoid eating oily or spicy foods. Contact your doctor if nausea and vomiting worsen.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices, to keep you hydrated. Take no medication on your own to manage diarrhea. Contact your doctor if your diarrhoea does not improve.

Stomach pain:

Try to rest and relax. Consume small meals regularly. Keep a heating pad on your stomach. Contact your doctor if your stomach pain worsens.

Skin rash:

Avoid a hot water bath as it irritates the skin and does not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturisers to soothe and hydrate the affected area. Contact your doctor if the rashes worsen.

WARNING & PRECAUTIONS

PREGNANCY

CHESTON EXPECTORANT is not recommended for use in pregnancy unless considered necessary. Contact your doctor before taking it.

BREASTFEEDING

CHESTON EXPECTORANT is not recommended for use in breastfeeding women unless considered clearly necessary as it may pass through the breast milk. Contact your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate machines if you feel drowsiness, dizziness and blurred vision after taking CHESTON EXPECTORANT.

ALCOHOL

Avoid alcohol consumption while taking CHESTON EXPECTORANT as it may increase drowsiness.

KIDNEY

CHESTON EXPECTORANT should be used with caution in patients with severe kidney disease. Contact your doctor before taking it.

LIVER

CHESTON EXPECTORANT should be used with caution in patients with severe liver disease. Contact your doctor before taking it.

ALLERGY

Do not use CHESTON EXPECTORANT if you are allergic to Bromhexine, Chlorpheniramine maleate, Guaifenesin or other ingredients of the medicine.

LUNGS

CHESTON EXPECTORANT should be used with caution in patients with asthma, bronchitis, bronchiectasis or chronic lung disorders. Contact your doctor before taking it.

HEART DISEASE

CHESTON EXPECTORANT is not recommended for use in patients with severe hypertension and severe coronary artery disease and should be used with hypotension, ischaemic heart disease or cardiovascular collapse. Contact your doctor before taking it.

OTHERS

CHESTON EXPECTORANT is not recommended for use if you have:

porphyria

Before taking CHESTON EXPECTORANT, inform your doctor if you have:

peptic ulcer
diabetes mellitus
increased intraocular pressure (glaucoma)
hyperthyroidism or thyrotoxicosis
prostatic enlargement or urinary retention
fits
intestinal obstruction
intolerance to sugars
urine test for sugars
low salt diet

Use in Paediatrics:

CHESTON EXPECTORANT should be used with caution in children aged 2 to 12 years of age. Contact your doctor before taking it.

Use in Geriatrics:

CHESTON EXPECTORANT should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking it.

INTERACTIONS

A. Drug-Drug interactions:

Before taking CHESTON EXPECTORANT, inform your doctor if you are taking any of the following medicine:

monoamine oxidase (MAO) inhibitors Ex. moclobemide (medicines used for depression)
antibiotics such as ampicillin, amoxicillin, erythromycin or oxytetracycline (medicines used for bacterial infections)
phenytoin (medicines used to manage fits)
benzodiazepines Ex. diazepam, lorazepam (medicines used for anxiety, fits)
paracetamol (medicines used for pain and fever)

Overdosage:

If you or anyone else accidentally take too much of CHESTON EXPECTORANT, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting, diarrhoea, indigestion, drowsiness, fever, ataxia, excitement, tremors, psychosis, hallucinations and fits, dilated pupils, dry mouth and facial flushing. Cardiorespiratory collapse, coma and even death.

SYNOPSIS

Drug	:	Bromhexine, Chlorpheniramine maleate and Guaifenesin
Pharmacological Category	:	Mucolytic, Antihistamine and Expectorant
Therapeutic Indication	:	Cough
Dosage Forms	:	Syrup, Expectorant

MORE INFORMATION

Keep CHESTON EXPECTORANT out of the sight and reach from children
Store CHESTON EXPECTORANT below 30°C

FAQs ABOUT CHESTON EXPECTORANT

Q: What is CHESTON EXPECTORANT and how does it work?

A: CHESTON EXPECTORANT is a combination of bromhexine, chlorpheniramine maleate and guaifenesin, which belongs to the group of medicines called mucolytics, antihistamines and nasal decongestants. It is used to manage the symptoms of a productive cough.

Q: Can I use CHESTON EXPECTORANT with children?

A: Yes. In children aged 2 to 12 years, CHESTON EXPECTORANT should be used with caution. Contact your doctor before taking it.

Q: Is CHESTON EXPECTORANT safe during pregnancy?

A: No. CHESTON EXPECTORANT is not recommended for use in pregnancy unless clearly necessary. Contact your doctor before taking it.

Q: Does CHESTON EXPECTORANT cause drowsiness?

A: Yes. CHESTON EXPECTORANT may cause drowsiness. Try to rest and relax. Get enough sleep. Do not drive or operate any machines if you feel drowsy. Do not consume alcohol, as it increases drowsiness. Contact your doctor if your drowsiness does not improve.

Q: What are the side effects of taking CHESTON EXPECTORANT?

A: The most common side effects of taking CHESTON EXPECTORANT are drowsiness and sedation, change in concentration, incoordination, dizziness, headache, blurred vision, nausea, vomiting, dry mouth and fatigue. If your symptoms worsen, consult your doctor.

REFERENCES

1. KD Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 219, 220, 218.

2. Delpharm Reims S.A.S. Health Products Regulatory Authority (HPRA). Revised in September 2021] [Accessed on 23rd July 2022] https://www.hpra.ie/img/uploaded/swedocuments/4550f813-c219-4e0a-b51a-5e6ed8a8e9f0.pdf

3. Farmaclair. Electronic Medicines Compendium (EMC). Revised in March 2022] [Accessed on 23rd July 2022] https://www.medicines.org.uk/emc/files/pil.3928.pdf

4. Reckitt Benckiser Healthcare (UK) Limited. Electronic Medicines Compendium (EMC). Revised in May 2016] [Accessed on 23rd July 2022] https://www.medicines.org.uk/emc/files/pil.8440.pdf

5. Reckitt Benckiser Healthcare (UK) Limited. Health Products Regulatory Authority (HPRA). [Accessed on 23rd July 2022] http://www.hpra.ie/img/uploaded/swedocuments/33802379-fb3b-42e2-a664-44a2ae2b4657.pdf

6. Cheston Expectorant (Bromhexine, Chlorpheniramine maleate and Guaifenesin). [Revised in November 2013] [Accessed on 23rd July 2022] https://www.ciplamed.com/content/Cheston-expectorantdt

AUTHOR DETAILS

Written By Dr. Dhivakaran R - BDS

Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)

Last updated on 06 Jan 2023 | 05:00 PM(IST)

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