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Introduction About CETROLIX 0.25MG INJECTION
CETROLIX 0.25MG INJECTION contains Cetrorelix which belongs to the group of medicines called Gonadotrophin-releasing hormone antagonists. It is used to manage premature ovulation (early release of eggs from ovaries). It is typically used among women during assisted reproductive techniques, where it helps the doctors to collect fertile eggs from the women’s body at the appropriate time.
CETROLIX 0.25MG INJECTION stops your body from releasing an egg until it becomes fully matured. When your eggs reach the optimum maturity, your doctor will give you another medicine that will help in releasing them.
Before receiving CETROLIX 0.25MG INJECTION inform your doctor if you have any liver or kidney problems. It should not be used in pregnant women after successful conception. It is also not recommended for use in breastfeeding women and in children or adolescents (aged below 18 years).
The most common side effect of receiving CETROLIX 0.25MG INJECTION is irritation, redness, itching and swelling at the site of injection. Consult your doctor if it troubles you.
Uses Of CETROLIX 0.25MG INJECTION
It is used among women undergoing assisted reproductive techniques to:
- prevent premature ovulation (release of immature eggs from ovaries)
- prevent premature LH surge
How CETROLIX 0.25MG INJECTION Works
CETROLIX 0.25MG INJECTION works by managing the early release of a hormone called luteinizing hormone, which controls ovulation. This stops your body from releasing an egg to early during the menstrual cycle which helps the doctors to collect fully grown eggs from the women’s body among women undergoing assisted reproductive techniques to become pregnant.
How to use CETROLIX 0.25MG INJECTION
CETROLIX 0.25MG INJECTION will be given to you by a doctor or a nurse beneath the skin (subcutaneously) of your belly. It can also be self-administered by the patient if instructed by the doctor. Carefully follow the instructions given by your doctor in case of self-administration.
Your doctor will decide the correct dose, time of administration and duration of therapy depending upon your body condition.
Side Effects Of CETROLIX 0.25MG INJECTION
Common
- injection site reactions (redness, itching, swelling or mild short or lasting irritation)
Uncommon
- headache
- nausea
Contact your doctor immediately if you experience any of the following side effects after receiving CETROLIX 0.25MG INJECTION:
- signs of ovarian hyperstimulation syndrome (such as lower abdominal pain with sensation of nausea or vomiting, weight gain, difficulty in breathing, difficulty in passing urine, enlarged ovaries and fluid build-up in chest or abdomen)
- signs of allergic reactions (such as skin rash, itching, redness, raised lumps, runny nose, irregular or fast heartbeat, swelling of the eyes, face, lips, tongue or throat leading to difficulty in breathing or swallowing, dizziness)
How To Manage Side Effects
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Injection Site Reactions
Place an ice pack on the affected area. Do not frequently move the injection site. Consult your doctor if the symptom did not improve.
Nausea And Vomiting
Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your symptom worsens.
Warning & Precautions
Pregnancy
ContraindicatedCETROLIX 0.25MG INJECTION is not recommended for use in pregnant women. Therefore, consult your doctor before receiving it.
Breastfeeding
ContraindicatedCETROLIX 0.25MG INJECTION is not recommended for use in breastfeeding women. Therefore, consult your doctor before receiving it.
Driving and Using Machines
SafeCETROLIX 0.25MG INJECTION does not affect your ability to drive or operate machinery.
Kidney
Consult your doctorCETROLIX 0.25MG INJECTION is not recommended for use in patients with severe kidney disease. It should be used with caution in patients with other kidney problems. Therefore, inform your doctor before receiving it.
Liver
Use with CautionCETROLIX 0.25MG INJECTION should be used with caution in patients with liver diseases. Therefore, inform your doctor before receiving it.
Allergy
ContraindicatedTalk to your doctor before receiving CETROLIX 0.25MG INJECTION if you are allergic to Cetrorelix.
Use In Pediatrics
ContraindicatedCETROLIX 0.25MG INJECTION is not indicated for use in children and adolescents (aged below 18 years).
Use In Geriatrics
Consult your doctorCETROLIX 0.25MG INJECTION is not intended for use in elderly patients (aged 65 years or older).
Interactions
A. Drug-Drug interactions:
Before receiving CETROLIX 0.25MG INJECTION, inform your doctor if you are taking any other medicines including prescription medicines and all over-the-counter health or herbal supplements.
Overdosage:
If CETROLIX 0.25MG INJECTION was administered to you by a doctor or a nurse in a hospital, it is unlikely to receive an overdose. If you overdosed this medicine during self-administration, consult your doctor for advice immediately.
Synopsis
| Drug | : | Cetrorelix |
| Pharmacological Category | : | Gonadotrophin-releasing hormone antagonists |
| Therapeutic Indication | : | Premature ovulation |
| Dosage Forms | : | Injection |
More Information
- Keep CETROLIX 0.25MG INJECTION out of reach of children
- Store CETROLIX 0.25MG INJECTION in a refrigerator between 2-8°C
FAQs About CETROLIX 0.25MG INJECTION
Q: What is the use of CETROLIX 0.25MG INJECTION?
A: CETROLIX 0.25MG INJECTION is used to manage premature ovulation (early release of eggs from ovaries). It is typically used among women during assisted reproductive techniques, where it helps the doctors to collect fertile eggs from the women’s body at the appropriate time.
Q: How CETROLIX 0.25MG INJECTION works?
A: CETROLIX 0.25MG INJECTION works by managing the early release of a hormone called luteinizing hormone, which controls ovulation. This stops your body from releasing an egg to early during the menstrual cycle.
Q: How CETROLIX 0.25MG INJECTION is administered?
A: CETROLIX 0.25MG INJECTION will be given to you by a doctor or a nurse beneath the skin (subcutaneously). It can also be self-administered by the patients if advised by the physician. Carefully, follow the instructions given by the doctor in case of self-administration.
Q: What precautions must be followed while receiving CETROLIX 0.25MG INJECTION?
A: Before receiving CETROLIX 0.25MG INJECTION inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you are pregnant or breastfeeding before this medicine is administered to you. Regularly visit your doctor and perform all blood tests and ultrasounds recommended by him/her without fail.
Q: Is CETROLIX 0.25MG INJECTION safe?
A: CETROLIX 0.25MG INJECTION is considered safe at the doses prescribed by the physician. However, consult your doctor if you experience any unusual side effects
Q: What are the common side effects of receiving CETROLIX 0.25MG INJECTION?
A: The most common side effect of receiving CETROLIX 0.25MG INJECTION is irritation, redness, itching and swelling at the site of injection. Consult your doctor if it troubles you.
Q: Can I stop receiving CETROLIX 0.25MG INJECTION once my symptoms subside?
A: Do not stop taking CETROLIX 0.25MG INJECTION without consulting your doctor. You need to receive CETROLIX 0.25MG INJECTION for the duration recommended by your doctor to achieve better results.
Q: How CETROLIX 0.25MG INJECTION helps in becoming pregnant?
A: CETROLIX 0.25MG INJECTION manages premature ovulation. It stops your body from releasing an immature egg during the menstrual cycle. Your doctor may prescribe this medicine to you if your body release eggs too early before reaching maturity. When your eggs reach the optimum maturity level, your doctor will give you another medicine that will help in releasing them. Therefore, this medicine helps your doctor to collect matured eggs that might support pregnancy among women undergoing assisted fertility techniques to become pregnant.
References
1. KD. Tripathi. Anterior pituitary Hormones. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 243.
2. Heng-Ju Chen Yu-Hung Lin, Bih-Chwen Hsieh, Kok-Min Seow, Jiann-Loung Hwang and Chii-Ruey Tzeng. Is a lower dose of cetrorelix acetate effective for prevention of LH surge during controlled ovarian hyperstimulation? NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. July 2006. [Accessed on 24th March 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506367/
3. Merck Serono Ltd. Cetrotide 0.25 mg powder and solvent for solution for injection. Electronic Medicines Compendium. [Revised in January 2021]. [Accessed on 24th March 2023] https://www.medicines.org.uk/emc/files/pil.1605.pdf
4. EMD Serono, Inc. Cetrotide (Cetrorelix acetate for injection) 0.25 and 3mg. U.S. Food and Drug Administration. [Revised in April 2008]. [Accessed on 24th March 2023] https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021197s010lbl.pdf
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