Caldob Cream 30gm

Introduction About CALDOB CREAM

CALDOB CREAM is a combination of Calcium Dobesilate, Hydrocortisone Acetate, Lignocaine and Zinc Oxide which belong to the group of medicines called Anti-haemorrhoids. It is used to manage haemorrhoids or piles (lumps inside or around your anus) and anal fissures (a small tear in the lining of anus) and constipation.

CALDOB CREAM is not recommended for use if you have tuberculous or fungal lesions or skin vaccinia (viral infection), varicella (chicken pox) and acute herpes simplex infection. Consult with your doctor before using it. CALDOB CREAM should be used with caution in patients with lung, liver and heart problems. CALDOB CREAM can be used during pregnancy only if clearly necessary. It should be used with caution in breastfeeding women. Consult your doctor before using the medicine.

CALDOB CREAM is not recommended for use in children and adolescents under 12 years of age. It should be used with caution in elderly patients. The most common side effects of using CALDOB CREAM are burning, irritation, redness, itchiness at the application site. Consult your doctor if any of the side effects worsen.

Uses Of CALDOB CREAM

It is used to manage:

• haemorrhoids
• anal fissures
• constipation

How CALDOB CREAM Works

Calcium Dobesilate is a vasoprotective medicine that works by strengthening the blood vessels at the affected site and also promote fast healing. Lignocaine is a local anaesthetic which blocks the transmission of pain signals from nerves to brain and Hydrocortisone belongs to the class of steroids works by decreasing itching, inflammation, redness and swelling. Zinc oxide is an astringent, which helps to reduce painful swelling and shrink the haemorrhoids. It also protects the skin on the anus from infections. Thus CALDOB CREAM helps to shrink pile mass and heals anal fissure effectively.

How to use CALDOB CREAM

Apply CALDOB CREAM as advised by your physician. It is for external use only. Wash your hands before and after use. Apply a thin layer of this medicine over the affected area with the help of an applicator or as directed by physician. Avoid the medicine in contact with your eyes, ears, nose or mouth. If accidental exposure occurs, wash your eyes with water and seek immediate medical attention. 

Side Effects Of CALDOB CREAM

Warning & Precautions

Pregnancy

Monitoring required

CALDOB CREAM should be used during pregnancy only if clearly necessary. Consult your doctor before using it.

Breastfeeding

Use with Caution

CALDOB CREAM should be used with caution in breastfeeding women. Consult your doctor before using it.

Liver

Use with Caution

CALDOB CREAM should be used with caution in patients with liver problems. Consult with your doctor before using it.

Allergy

Contraindicated

Do not use CALDOB CREAM if you are allergic to Calcium Dobesilate, Hydrocortisone Acetate, Lignocaine, Zinc Oxide or any other ingredient of this medicine.

Lungs

Use with Caution

CALDOB CREAM should be used with caution in patients with lung problems. Consult with your doctor before using it.

Heart Disease

Use with Caution

CALDOB CREAM should be used with caution in patients with severe shock and heart block. Consult with your doctor before using it.

Use In Pediatrics

Contraindicated

CALDOB CREAM is not recommended for use in children and adolescents under 12 years of age. Consult your doctor before using it.

Use In Geriatrics

Use with Caution

CALDOB CREAM should be used with caution in elderly patients. Consult your doctor before using it.

Interactions

A. Drug-Drug Interactions:

Before using CALDOB CREAM, inform your doctor if you are using any of the following medicine:

• medicine used to manage chest pain, high blood pressure (ex. nitroglycerin, nitroprusside, nitric oxide, nitrous oxide)
• anaesthetics (medicines used to produce temporary loss of consciousness (ex. benzocaine, lidocaine, bupivacaine, mepivacaine)
• medicine used for cancer (ex. cyclophosphamide, flutamide, rasburicase, ifosfamide, hydroxyurea)
• antibiotics (medicine used to manage infections) (ex. dapsone, sulfonamides, nitrofurantoin, para-aminosalicylic acid)
• medicine used for malaria (ex. quinine, chloroquine, primaquine)
• medicine used to manage fits (ex. phenytoin, sodium valproate, phenobarbital)
• acetaminophen (used to relieve pain and fever)
• metoclopramide (used for nausea and vomiting)
• sulfasalazine (used for ulcerative colitis and Crohn’s disease)
• oral laxatives (used to manage constipation) (ex. lactulose)
• antiarrhythmics (used to manage irregular heartbeats) (ex. quinidine)

Overdosage:

If you or anyone else accidentally ingested or used too much of CALDOB CREAM, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep CALDOB CREAM out of reach of children
• Store CALDOB CREAM at room temperature

FAQs About CALDOB CREAM

Q: Is CALDOB CREAM safe to use?

A: Yes. CALDOB CREAM is well-tolerated, with a consistent safety profile and provides an efficient fast and safe symptomatic relief from haemorrhoids or piles, anal fissures, bleeding with pain and itching. It also helps to promote easy evacuation of stools. Consult your doctor before using it.

Q: What lifestyle modifications have to be taken while using CALDOB CREAM?

A: Take bath with warm water while using this medicine. This will soothe the area and will also aid in pain. Take fiber rich foods in your diet such as fresh fruits, vegetables and whole grain bread and cereals to help in digestion and ensure speedy recovery. Make sure to avoid spicy, oil-rich food and drink at least 6-8 glasses of water daily and exercise regularly to maintain healthy bowel movement.

Q: How to use CALDOB CREAM?

A: Apply CALDOB CREAM as advised by your physician. It is for topical use only. Wash your hands before and after use. Apply a thin layer of this medicine over the affected area with the help of an applicator or as directed by physician. Avoid the medicine in contact with your eyes, ears, nose or mouth. If accidental exposure occurs, wash your eyes with water and seek immediate medical attention. 

Q: Can I stop using CALDOB CREAM when my symptoms are relieved?

A: No, do not stop using CALDOB CREAM and complete the full course of management. Your symptoms may improve before the condition is completely managed. Consult your doctor before discontinue the medicine Otherwise it may lead to worsening of your condition.

Q: Is CALDOB CREAM safe to use in pregnant women?

A: CALDOB CREAM should be used during pregnancy only if clearly necessary. Inform your doctor if you are pregnant or planning for pregnancy before using this medicine.

References

1. K.D. Tripathi. Drugs Acting on Skin and Mucous Membranes, Local Anaesthetics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 895, 887, 360.

2. Bethesda (MD). Calcium Dobesilate. NIH. National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on Feb 13th, 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Calcium%20Dobesilate

3. Bethesda (MD). Hydrocortisone. NIH. National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on Feb 13th, 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Hydrocortisone

4. Bethesda (MD). Lignocaine. NIH. National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on Feb 13th, 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Lignocaine

5. Bethesda (MD). Zinc Oxide. NIH. National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on Feb 13th, 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Zinc%20Oxide

6. The Boots Company. Electronic Medicines Compendium (EMC). [Revised in July 2016] [Accessed on Feb 13th, 2024] https://www.medicines.org.uk/emc/files/pil.6730.pdf

7. Lidocaine and Hydrocortisone Cream. Daily Med: National Library of Medicine: National Institute of Health. [Revised in February 2022] [Accessed on Feb 13th, 2024] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5c57a310-8d46-4862-bf2a-a7e4fd5bee57

8. Hydrocortisone Ointment. Daily Med: National Library of Medicine: National Institute of Health. [Revised in January 2022] [Accessed on Feb 13th, 2024] https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=7ba59aa6-b828-4048-bf86-90c90d9894a0&type=pdf

9. Lidocaine Ointment. Daily Med: National Library of Medicine: National Institute of Health. [Revised in May 2018] [Accessed on Feb 13th, 2024] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=12639881-632d-445d-9ff5-b84567f49179

10. Calcium Dobesilate, Lignocaine, Hydrocortisone Acetate, Zinc oxide Cream. MK Medicine. [Accessed on Feb 13th, 2024] https://www.mkmedicine.in/calcium-dobesilate-0.25-lignocaine-3-hydrocortisone-acetate-0.25-zinc-5.html

11. SWIFT CREAM (Calcium Dobesilate, Lignocaine, Hydrocortisone Acetate, Zinc oxide). Invision Medi Sciences Pvt. Ltd. [Accessed on Feb 13th, 2024] http://www.invisionmedi.com/category/swift-cream.htm

12. Pilesrin Cream (Calcium Dobesilate, Lignocaine, Hydrocortisone Acetate, Zinc oxide). Orion Life science Ltd. [Accessed on Feb 13th, 2024] https://www.orionlifes.com/product/calcium-dobesilatehydrocortisone-lignocaine-zinc-cream/

13. Doberest (Calcium Dobesilate, Lignocaine, Hydrocortisone Acetate, Zinc oxide). Arlak Biotech Pvt. Ltd. [Accessed on Feb 13th, 2024] https://www.arlakbiotech.com/products-offering/calcium-dobesilate-lignocalne-hydrocortisonezinc-cream/

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS

Last updated on 17 Feb 2024 | 09:43 AM(IST)