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Glaxosmithkline Pharmaceuticals Ltd

Betnesol Tablet 20'S

Hormonal Therapy
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    Introduction About BETNESOL TABLET

    BETNESOL TABLET contains Betamethasone, which belongs to the group of medicines called Corticosteroids. It is used to manage many different types of conditions, including asthma and severe allergic reactions, certain conditions of the blood, rheumatoid arthritis (chronic inflammatory diseases affecting the joints), autoimmune diseases (like systemic lupus erythematosus (SLE) and polyarteritis nodosa), inflammatory conditions of the skin, kidney (like acute interstitial nephritis), bowels (like ulcerative colitis and Crohn's disease) and heart, some connective tissue disorders and malignant lymphoma. BETNESOL TABLET also help to manage organ transplant rejection following organ transplant surgery.

    Your doctor might recommend you take relevant tests to understand your condition before starting management with BETNESOL TABLET. Avoid drinking alcohol while using BETNESOL TABLET as it may worsen your existing condition.

    BETNESOL TABLET is not recommended for use in patients with an infection and who are not taking antibiotics. Before taking BETNESOL TABLET, inform your doctor if you have kidney, liver, heart problems, underactive thyroid gland, severe mental illness, tuberculosis, epilepsy, hypertension, pheochromocytoma, glaucoma, or diabetes.

    BETNESOL TABLET should be used with caution among women who are pregnant or breastfeeding. BETNESOL TABLET should be used with caution in children, adolescents, and elderly patients. Contact your doctor if any of the above symptoms worsen. Consult with your doctor if you experience any unusual behaviors, self-harming or depression, etc. after taking BETNESOL TABLET.

    Uses Of BETNESOL TABLET

    It is used to manage many different types of conditions including:

    • Asthma
    • Severe allergic reactions
    • Certain conditions of the blood
    • Rheumatoid arthritis
    • Autoimmune diseases (like systemic lupus erythematosus (SLE) and polyarteritis nodosa)
    • Inflammatory conditions of the skin, kidney (like acute interstitial nephritis), bowels (like ulcerative colitis and Crohn’s disease), and heart
    • Some connective tissue disorders
    • Malignant lymphoma
    • Prevents organ transplant rejection following an organ transplant surgery

    How BETNESOL TABLET Works

    BETNESOL TABLET inhibits certain chemical pathways in the body which reduces the formation of substances (arachidonic acid) that causes pain. It also enhances anti-inflammatory genes like interleukin 10. Thus, it helps in reducing pain and inflammation.

    How to use BETNESOL TABLET

    Take BETNESOL TABLET as advised by your doctor. Swallow the medicine with enough water. Do not crush or chew the medicine. Try to take BETNESOL TABLET daily at the same time.  Your doctor will decide the correct dose and duration of BETNESOL TABLET for you depending on your age, body weight and disease condition.

    Side Effects Of BETNESOL TABLET

    Rare

    Stop taking BETNESOL TABLET and contact your physician immediately if you experience any of the following side effects:

    • feeling depressed and suicidal thoughts
    • feeling high (mania) or moods swings
    • feeling anxious, having sleeping problems, having difficulty thinking or being confused, and losing the memory
    • feeling, hearing or seeing things that do not exist
    • having strange and frightening thoughts
    • changing how you act or having feelings of being alone
    • allergic reactions (signs include rash, swallowing or breathing problems, swelling of the lips, face, throat, or tongue
    • blistering or bleeding the skin including around the nose, lips, eyes, mouth, and genitals
    • Stevens-Johnson syndrome (flu-like symptoms and fever)

    Warning & Precautions

    Pregnancy

    BETNESOL TABLET should be used with caution by pregnant women as it may slow down the baby’s growth or may temporarily affect baby’s body and heart movements. If you become pregnant while taking BETNESOL TABLET, inform your doctor and do not stop taking the medicine unless are told to do so by your doctor. Consult your doctor before taking BETNESOL TABLET.

    Breastfeeding

    BETNESOL TABLET should be used with caution by breastfeeding women as it may pass through the breast milk. Consult your doctor before taking BETNESOL TABLET.

    Kidney

    BETNESOL TABLET should be used with caution in patients with kidney diseases. Consult your doctor taking BETNESOL TABLET.

    Liver

    BETNESOL TABLET should be taken with caution in patients with liver diseases. Consult your doctor before taking.

    Allergy

    Do not take BETNESOL TABLET if you are allergic to Betamethasone or any of the other ingredients of this medicine.

    Heart Disease

    BETNESOL TABLET should be used with caution in patients with heart diseases such as patients who had a recent heart attack. Consult your doctor taking BETNESOL TABLET.

    Others

    BETNESOL TABLET is not recommended for use if you have:

    • an infection and / or taking antibiotics

    Before taking BETNESOL TABLET, inform your doctor if you have:

    • tuberculosis (TB)
    • epilepsy (fits)
    • glaucoma (raised eye pressure)
    • chickenpox, shingles, or measles, or having contact with a person having these
    • diabetes
    • underactive thyroid gland
    • myasthenia gravis
    • to be vaccinated or vaccinated
    • hypertension (high blood pressure)
    • osteoporosis (thinning of bones specifically in postmenopausal women)
    • pheochromocytoma (tumor of adrenal gland)
    • had an ulcer in stomach or gut
    • blurred vision or other visual problems
    • severe mental illness

    Use in pediatrics:

    BETNESOL TABLET should be used with caution in children. Your doctor will decide the correct dose depending upon your child’s age, health condition and body weight. consult with your child’s doctor.

    Use in geriatrics:

    BETNESOL TABLET should be used with caution in elderly patients. Consult your doctor before taking BETNESOL TABLET.

    Interactions

    A. Drug-Drug interactions:

    Before taking BETNESOL TABLET, inform your doctor if you are taking any of the following medicine:

    • insulin or oral antidiabetic drugs (Ex. metformin, sitagliptin, glimepiride)
    • medicines used to manage HIV (Ex. ritonavir, cobicistat)
    • medicine used for hypertension (Ex. amlodipine, telmisartan), heart problems (Ex. digoxin), hypotension (Ex. ephedrine)
    • water tablets (diuretics) used to manage fluid retention (Ex. furosemide)
    • medicines used for thinning of the blood (Ex. warfarin)
    • medicines used to manage pain and inflammation such as non-steroidal anti-inflammatory drugs (Ex. ibuprofen), salicylates (Ex. aspirin)
    • medicines used to manage glaucoma (Ex. acetazolamide)
    • medicines used for myasthenia gravis (Ex. pyridostigmine)
    • medicines used to manage tuberculosis (Ex. rifampicin, rifabutin)
    • medicines used to manage epilepsy (Ex. carbamazepine, phenytoin, primidone, phenobarbitone, aminoglutethimide)
    • medicines used as oral contraceptives to manage pregnancy (Ex. estradiol, levonorgestrel)
    • medicines used to induce abortion in early pregnancy (Ex. mifepristone)
    • growth hormones to manage conditions like growth failure and short stature (Ex. somatropin)
    • medicines used as muscle relaxants (Ex. vecuronium)
    • medicines used to manage infections (Ex. fluoroquinolones such as ciprofloxacin, levofloxacin)
    • medicines used to improve symptoms of mental illnesses (Ex. quetiapine)
    • medicines used to manage bad acne (Ex. tretinoin)
    • medicines used to manage ulcers (Ex. carbenoxolone)
    • amphotericin-B (used to manage fungal infections)
    • theophylline (used to manage asthma and other allergic conditions)

    Overdosage

    If you or anyone else accidentally take too much of BETNESOL TABLET, consult your doctor immediately or visit the nearby hospital.

    Synopsis

    Drug :  

    Betamethasone

    Pharmacological Category :  

    Corticosteroids

    Therapeutic Indication :  

    Asthma, severe allergic reactions, certain conditions of the blood, rheumatoid arthritis, autoimmune diseases (like systemic lupus erythematosus (SLE) and polyarteritis nodosa), inflammatory conditions of the skin, kidney (like acute interstitial nephritis), bowels (like ulcerative colitis and Crohn's disease) and heart, some connective tissue disorders, malignant lymphoma. Management of organ transplant rejection

    Dosage Forms :  

    Tablet, Gel, Cream, Ointment, Lotion, Oral drops, Oil, Eye/Ear drops, Injection

    More Information

    • Keep BETNESOL TABLET out of reach from children
    • Store BETNESOL TABLET at a temperature not more than 25°C

     

    FAQs About BETNESOL TABLET

    Q: What is the use of BETNESOL TABLET?

    A: BETNESOL TABLET is used to manage various illnesses involving inflammation in the body. It is used to manage asthma, severe allergic reactions, rheumatoid arthritis, autoimmune diseases such as systemic lupus erythematosus (SLE) and polyarteritis nodosa, inflammatory conditions of the skin, kidney (acute interstitial nephritis or minimal change nephrotic syndrome), bowels (ulcerative colitis and Crohn’s disease) and heart, some connective tissue diseases, certain conditions of the blood and malignant lymphoma. It also helps in organ transplant rejection following organ transplant surgery.

    Q: Is it safe to use BETNESOL TABLET everyday?

    A: To reduce the risk of side effects, your doctor may recommend that you only use BETNESOL TABLET for a few weeks at a time or for a day or two each week. Always take as prescribed by the physician.

    Q: When should I take BETNESOL TABLET?

    A: Take BETNESOL TABLET as advised by your doctor. Swallow the medicine with enough water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

    Q: Is BETNESOL TABLET a steroid?

    A: Yes. BETNESOL TABLET is a potent steroid which inhibits certain chemical pathways in the body, which reduces the formation of substances (arachidonic acid) that cause pain. It also enhances anti-inflammatory properties which helps in reducing pain and inflammation.

    Q: What if I forget to take a dose of BETNESOL TABLET?

    A: If you forget a dose of BETNESOL TABLET, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the next scheduled dose at the prescribed time. Do not double the dose to make up for the missed dose, as this may increase the chances of developing side effects.

    Q: Is it safe to use BETNESOL TABLET during pregnancy and breastfeeding?

    A: BETNESOL TABLET should be used with caution in pregnant women as it may slow down the baby’s growth or may temporarily affect the baby’s body and heart movements. BETNESOL TABLET should be used with caution in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking BETNESOL TABLET.

    Q: When BETNESOL TABLET is not recommended?

    A: BETNESOL TABLET is not recommended for use if you have an infection and are not taking antibiotics for it. Consult with your doctor before taking BETNESOL TABLET.

    Q: Can I stop taking BETNESOL TABLET on my own?

    A: It is important to keep taking BETNESOL TABLET till the time your doctor has prescribed. Do not stop taking it on your own, even if your symptoms resolve and you feel better. If you stop taking BETNESOL TABLET suddenly, you may experience fever, joint and muscle pain, itching, mood changes, dizziness, loss of weight, fainting, or headache. Consult with your doctor if you wish to discontinue taking BETNESOL TABLET.

    Q: Is BETNESOL TABLET safe to use in patients with heart problems?

    A: BETNESOL TABLET should be used with caution in patients with heart diseases such as patients who had a recent heart attack. Consult your doctor taking it.

    Q: Is BETNESOL TABLET safe to use in patients with liver and kidney problems?

    A: BETNESOL TABLET should be used with caution in patients with severe liver and kidney problems. Contact your doctor before taking the medicine.

    References

    1. KD Tripathi. Corticosteroids. Drugs Essentials of medical pharmacology. Seventh edition. 2013. Page – 289.

    2. Komal Gaur and Barna Ganguly. Effect of Single Dose Betamethasone Administration in Pregnancy on Maternal and Newborn Parameters. Journal of Clinical and Diagnostic Research. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. May 2017. [Accessed on 18th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483699/

    3. Betamethasone. NIH National Library of Medicine, National center for biotechnology information. Pubchem. [Revised in August 2022] [Accessed on 18th August 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Betamethasone

    4. The Health Products Regulatory Authority. Betnesol. [Revised in November 2021] [Accessed on 18th August 2022] http://www.hpra.ie/img/uploaded/swedocuments/410651d2-1e55-4921-bc55-503a8d675d07.pdf

    5. ROMA Pharmaceuticals Limited. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 18th August 2022] https://www.medicines.org.uk/emc/files/pil.13323.pdf

    6. Comed Chemicals. Belar Tab. [Accessed on 18th August 2022] https://www.comedchemicals.com/product?id=10

    7. Comed Chemicals. Belar Forte Tab. [Accessed on 18th August 2022] https://www.comedchemicals.com/product?id=25

    Useful Diagnostic Tests

    • Absolute Eosinophil Count
    • Peripheral Smear Examination
    • Total IgE

    Author Details

    Written By Dr. Janet.C - Pharm.D
    Reviewed For Accuracy By Dr. M N Himaja - MBBS
    Last updated on 19 Mar 2024 | 04:25 PM(IST)
    Lab updated