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Introduction About AVINO AM TABLET
AVINO AM TABLET is used to manage hypertension and angina pectoris (chest pain caused due to lack of oxygen supply to the heart). It can also be used to reduce the risk of heart attack (myocardial infarction) among heart patients.
It contains a combination of Amlodipine and Atenolol which belongs to the group of medicine called Antihypertensive agents.
Take AVINO AM TABLET as advised by your physician. Avoid drinking grapefruit juice while taking AVINO AM TABLET, as it could further decrease your blood pressure and may make you feel dizzier, drowsier or faint.
Before taking AVINO AM TABLET, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have asthma, diabetes, overactive thyroid gland or low blood volume as a precaution.
AVINO AM TABLET is not recommended for use in patients with other severe heart problems apart from hypertension and angina (such as heart failure). It is also not suitable for use in patients with severe hypotension (low blood pressure).
Consult your doctor before taking AVINO AM TABLET if you are pregnant or breastfeeding. The most common side effects of taking AVINO AM TABLET are swelling of ankles or other body parts, headache, dizziness, sleepiness, tiredness, racing heartbeat, indigestion, constipation, muscle cramps, cold hands and feet and slow heartbeat. Contact your doctor if any of these side effects trouble you.
Uses Of AVINO AM TABLET
AVINO AM TABLET is used in the management of the following cardiac conditions:
- Hypertension (high blood pressure)
- Angina (chest pain)
How AVINO AM TABLET Works
AVINO AM TABLET contains two medicines namely amlodipine and atenolol. Atenolol blocks the effects of certain hormones (adrenaline) in the body that naturally increases heart rate. This slows down the heartbeat and makes the heart to pump blood with a lesser force.
Amlodipine is a vasodilator. It relaxes the blood vessels supplying the heart which improves blood flow and oxygen supply to the heart muscles. Collectively, they reduce the strain on the heart and improves heart functions.
How to use AVINO AM TABLET
- Take AVINO AM TABLET as advised by your physician.
- Swallow the medicines with a glass of water. Do not crush or chew the medicine.
- AVINO AM TABLET can be taken with or without meals.
- Your doctor will prescribe the correct dosage and duration based on your health condition.
- Do not stop taking the medication abruptly without consulting your doctor, even if you feel better.
Side Effects Of AVINO AM TABLET
Like all medicines, AVINO AM TABLET may cause side effects in some individuals, although not everyone gets them.
Common Side Effects of AVINO AM TABLET:
- edema (swelling of the ankles or other body parts)
- headache, dizziness, sleepiness
- palpitations (fast heartbeat)
- flushing (redness and warmth of the skin)
- stomach pain, nausea, diarrhea, constipation, indigestion
- changes in bowel habit
- tiredness, weakness
- muscle pains
- cold hands and feet
- slow heartbeat
- insomnia (sleeplessness)
- changes in taste
- tingling sensation in limbs, loss of pain sensation
- low blood pressure
- increased sweating
- increased urination at night
- inability to obtain an erection, enlargement of the breasts in men
- joint pain, back pain
- weight gain or decrease in weight
Stop taking AVINO AM TABLET and contact your doctor immediately if you experience any of the following side effects:
- chest pain, shortness of breath (signs of heart attack)
- inflammation of pancreas (causing severe stomach pain that radiates to the back side of the body)
Warning & Precautions
Pregnancy
Monitoring requiredAVINO AM TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.
Breastfeeding
Use with CautionAVINO AM TABLET should be used with caution in breastfeeding women as it may pass through the breast milk to the nursing infant. Therefore, consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if you feel dizzy after taking AVINO AM TABLET.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking AVINO AM TABLET as it could make you feel dizzier.
Kidney
Use with CautionAVINO AM TABLET should be used with caution in patients with kidney problems (such as dialysis). Therefore, consult your doctor before taking it.
Liver
Use with CautionAVINO AM TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take AVINO AM TABLET if you are allergic to Atenolol, Amlodipine or to any other beta blockers (such as propranolol) or calcium antagonists (such as nifedipine, diltiazem).
Lungs
Use with CautionAVINO AM TABLET should be used with caution in patients who have or previously had any breathing problems such as asthma. Therefore, consult your doctor before taking it.
Heart Disease
Consult your doctorAVINO AM TABLET is not recommended for use in patients with severe heart problems such as heart failure, aortic stenosis (narrowing of arteries) or cardiogenic shock (inability of heart to pump blood). It should be used with caution in patients having a history of recent heart attack or heart failure. Therefore, consult your doctor before taking it.
Use In Pediatrics
ContraindicatedAVINO AM TABLET is not recommended for use in children and adolescents (aged below 18 years) due to lack of safety data. Therefore, consult your doctor for advice.
Use In Geriatrics
Use with CautionAVINO AM TABLET should be used with caution in the elderly patients. Therefore, consult your doctor before taking it.
Others
AVINO AM TABLET is not recommended for use if you:
- have severe low blood pressure (hypotension)
- have a very poor blood circulation
- have unmanaged phaeochromocytoma (a tumor present in the adrenal gland)
- have metabolic acidosis (high acid levels in the blood)
Before taking AVINO AM TABLET, inform your doctor if you:
- have severe uncontrollable increase in blood pressure (hypertensive crisis)
- have diabetes
- have low blood volume (loss of fluids from the body due to vomiting or diarrhea)
- have thyrotoxicosis (increased activity of the thyroid gland)
- have psoriasis (an autoimmune skin condition causing white patches)
- any scheduled for any operations or procedures
Interactions
A. Drug-Drug interactions:
Before taking AVINO AM TABLET, inform your doctor if you are taking any of the following medicines such as:
- other medicines used to manage high blood pressure and angina (such as nifedipine, verapamil, diltiazem, enalapril, ramipril, metoprolol, clonidine)
- ketoconazole, itraconazole (used to manage fungal infections)
- ritonavir, indinavir, nelfinavir (used in management of HIV infections)
- rifampicin, erythromycin, clarithromycin (used to manage bacterial infections)
- dantrolene (a medicine used to manage muscle spasms)
- medicines used to control elevated cholesterol levels (Ex. simvastatin)
- medicines used to manage graft rejection and to suppress immune functions (such as tacrolimus, sirolimus, temsirolimus, everlimus, cyclosporine)
- St. John’s wort (an herbal medicine used to manage depression)
- medicine used to manage irregular heartbeat (Ex. amiodarone, digoxin, quinidine or disopyramide)
- adrenaline (a medicine used to stimulate the heart)
- indomethacin or ibuprofen (medicines used for pain relief)
- medicines used to manage nose or sinus congestion and other cold remedies (such as montelukast, levocetirizine)
- medicines used to manage diabetes (Ex. insulin, metformin, glimepiride)
B. Drug-Food interaction:
Avoid drinking grapefruit juice while taking AVINO AM TABLET, as it could lead to further decrease your blood pressure and may make you feel dizzier, drowsier or faint.
Overdosage:
If you or anyone else accidentally took more AVINO AM TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include dizziness, fainting, light-headedness, weakness, shock, cool or clampy skin and shortness of breath.
Synopsis
| Drug | : | Amlodipine, Atenolol |
| Pharmacological Category | : | Calcium Channel Blocker, Beta blockers |
| Therapeutic Indication | : | Hypertension, Angina pectoris |
| Dosage Forms | : | Tablet, Capsule, Tabcap, Captab |
More Information
Storage
- Keep AVINO AM TABLET out of the sight and reach of children
- Store AVINO AM TABLET at room temperature
FAQs About AVINO AM TABLET
Q: What are the uses of AVINO AM TABLET?
A: AVINO AM TABLET is used to manage hypertension (also known as high blood pressure) and angina pectoris (chest pain caused by a lack of oxygen supply to the heart). By controlling blood pressure and improving oxygen supply to the heart, this medicine can also contribute to protect your heart from heart failure if you are suffering from previous history of heart attack.
Q: What type of medicine is AVINO AM TABLET?
A: AVINO AM TABLET is an antihypertensive medicine. Atenolol blocks the effects of certain hormones (adrenaline) in the body that naturally increase heart rate. This slows down the heartbeat and makes the heart pump blood with less force. Amlodipine is a vasodilator. It relaxes the blood vessels supplying the heart, which improves blood flow and oxygen supply to the heart muscles. Collectively, they reduce the strain on the heart and improve heart function.
Q: How do I take AVINO AM TABLET?
A: Take AVINO AM TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. AVINO AM TABLET can be taken with or without meals. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition. Continue to take AVINO AM TABLET for the stipulated duration instructed by your doctor to achieve better results.
Q: What should I do if I forget to take a dose of AVINO AM TABLET?
A: If you have missed a dose of AVINO AM TABLET, take it as soon as you remember. However, if it is time for the next dose of AVINO AM TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of AVINO AM TABLET to compensate for the missed ones.
Q: What precautions should be followed while taking AVINO AM TABLET?
A: Before taking AVINO AM TABLET, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have severe high or low blood pressure or other heart problems (such as narrowing of the arteries, cardiogenic shock, or a recent heart attack). Consult your doctor before taking AVINO AM TABLET if you are pregnant and breastfeeding. Regularly visit your doctor and take all the necessary blood tests recommended by your doctor without fail.
Q: Can I consume alcohol while taking AVINO AM TABLET?
A: Avoid consumption of alcohol while taking AVINO AM TABLET, as it might make you feel dizzy.
Q: What happens if I accidentally take more AVINO AM TABLET?
A: If you or anyone else accidentally took more AVINO AM TABLET, consult your doctor immediately. Symptoms of overdosage might include dizziness, fainting, light-headedness, weakness, shock, cool or clampy skin, and shortness of breath.
Q: Can AVINO AM TABLET cause ankle swelling?
A: AVINO AM TABLET may cause edema or swelling of the ankles in a few patients. If you experience ankle swelling, keep your legs on a table or slightly elevated from ground level. If this symptom bothers you, contact your doctor.
Q: What are the side effects of AVINO AM TABLET?
A: The most common side effects of taking AVINO AM TABLET are swelling of ankles or other body parts, headache, dizziness, sleepiness, tiredness, racing heartbeat, indigestion, constipation, muscle cramps, cold hands and feet, and a slow heartbeat. Contact your doctor if any of these side effects trouble you.
Q: Can I stop taking AVINO AM TABLET suddenly?
A: No. Do not stop taking AVINO AM TABLET without consulting your doctor. As hypertension is a chronic condition, long term management may be necessary to control its symptoms. Therefore, take AVINO AM TABLET as advised by your doctor for the stipulated duration. Premature discontinuation of therapy may increase your blood pressure once again.
Q: Can AVINO AM TABLET be taken during pregnancy?
A: AVINO AM TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.
Q: Can AVINO AM TABLET be taken during breastfeeding?
A: AVINO AM TABLET should be used with caution in breastfeeding women as it may pass through the breast milk to the nursing infant. Therefore, consult your doctor before taking it.
Q: Can I take other medicines with AVINO AM TABLET?
A: Before taking AVINO AM TABLET, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, non-prescription, or any herbal medicine, as these might interact with each other and cause serious side effects.
Q: Can the use of AVINO AM TABLET affect the liver?
A: Yes. AVINO AM TABLET should be used with caution in patients with liver problems. Consult your doctor before taking it.
Q: Can AVINO AM TABLET cause erectile dysfunction?
A: AVINO AM TABLET may cause problems in erection in a few individuals. Consult your doctor if it bothers you.
Q: Is AVINO AM TABLET safe to use in patients with heart problems?
A: AVINO AM TABLET is not recommended for use in patients with severe heart problems such as heart failure, aortic stenosis (narrowing of arteries), or cardiogenic shock (inability of the heart to pump blood). It should be used with caution in patients with a history of recent heart attacks or heart failure. Therefore, consult your doctor before taking it.
References
1. KD. Tripathi. Antiadrenergic agents and drugs for glaucoma. Antianginal and Other Anti-ischaemic Drugs, Antihypertensive Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 149, 549 & 562-563.
2. Gerald G. Briggs and Roger K. Freeman. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 196-198 and 306-316.
3. Gang Ling, Ai-jun Liu, Fu-ming Shen, Guo-jun Cai, Jian-guo Liu & Ding-feng Su. Effects of combination therapy with atenolol and amlodipine on blood pressure control and stroke prevention in stroke-prone spontaneously hypertensive rats. Acta Pharmacologica Sinica. November 2007. [Accessed on 3rd January 2023] click here
4. Kishen G. Bulsara; Manouchkathe Cassagnol. Amlodipine. StatPearls. NIH. National Library of Medicine, National Center for biotechnology information. PMC. PubMed Central. January 2022. [Accessed on 3rd January 2023] click here
5. Dr. Reddy’s Laboratories (UK) Ltd. Electronic Medicines Compendium (EMC). [Revised in July 2022] [Accessed on 3rd January 2023] click here
6. Zentiva Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 3rd January 2023] click here
7. Accord Healthcare Limited, Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 3rd January 2023] click here
8. Cipla Ltd. AMLOPRES AT Tablets (Amlodipine + Atenolol). Ciplamed. [Revised in December 2020]. [Accessed on 3rd January 2023] click here
9. Central Drugs Standard Control Organization. Amlodipine besylate eq. to Amlodipine 5mg+ Atenolol 50mg Besylate uncoated tablets. May 1996. [Accessed on 3rd January 2023] click here
10. Leeford Healthcare Pvt Ltd. Wellamo AT. [Accessed on 3rd January 2023] click here
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