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Introduction About AUGMENTIN DUO ORAL SUSPENSION
AUGMENTIN DUO ORAL SUSPENSION is used to manage bacterial infections such as middle ear and sinus infections, respiratory tract infections, genital tract infections, urinary tract infections, skin and soft tissue infections such as dental infections, bone and joint infections, septic abortion (any abortion complicated by uterine infection), and abdominal infections. The symptoms of a bacterial infection may include fever, difficulty breathing, pus formation, and pain.
It contains a combination of medicines called Amoxicillin and Clavulanic acid, which belongs to the group of medicines called Antibiotics. It works by preventing the growth of bacteria and helps clear up the infection.
Do not take AUGMENTIN DUO ORAL SUSPENSION if you have a history of hypersensitivity to beta-lactams, including penicillin and cephalosporins, or any other ingredients of this medicine. It is not recommended for use if you have a history of amoxicillin-clavulanate-associated jaundice or hepatic dysfunction.
Before taking AUGMENTIN DUO ORAL SUSPENSION, inform your doctor if you are suffering from hepatic or renal impairment. This medicine should be used with caution in pregnant women and only when necessary.
In breastfeeding women, it should be used with caution. AUGMENTIN DUO ORAL SUSPENSION should be used with caution in children (aged below 12 years) and elderly patients (above 50 years).
The common side effects associated with the use of AUGMENTIN DUO ORAL SUSPENSION are diarrhea, thrush (a fungal infection in the vagina, skin folds, or mouth), nausea, and vomiting. Contact your doctor immediately if any of the symptoms worsen.
Uses Of AUGMENTIN DUO ORAL SUSPENSION
It is used for managing bacterial infections such as:
How AUGMENTIN DUO ORAL SUSPENSION Works
AUGMENTIN DUO ORAL SUSPENSION helps in managing bacterial infection where amoxicillin is a penicillin that works by inhibiting the enzymes that help in the synthesis of an integral structural component of the bacterial cell wall whereas clavulanic acid is a beta-lactam (structurally related to penicillin) that works by inactivating an enzyme, namely beta-lactamase, thereby managing the inactivation of amoxicillin.
How to use AUGMENTIN DUO ORAL SUSPENSION
Take this medicine as advised by your physician.
Syrup/Oral Suspension:
- Shake well before use.
- Use the dosing syringe, cup, or spoon supplied with the pack to measure the dose accurately.
- A dosing syringe is recommended to dose a child below the age of 3 months accurately.
Dry syrup/dry suspension:
- Open the sachet, reconstitute the dry powder thoroughly in a glass of water, and swallow the mixture immediately.
Your doctor will determine the correct dose and duration for you depending on your age, body weight, and disease condition.
Side Effects Of AUGMENTIN DUO ORAL SUSPENSION
Common Side Effects of AUGMENTIN DUO ORAL SUSPENSION:
- diarrhoea
- thrush (fungal infection in the vagina, skin folds, or mouth)
- nausea
- vomiting
Stop taking AUGMENTIN DUO ORAL SUSPENSION and contact your doctor if you experience any of the following side effects:
- signs of allergic reactions such as skin rash, swelling on the face or mouth resulting in difficulty breathing or collapse
- signs of vasculitis (inflammation of blood vessels) such as raised red or purple spots on the skin
- inflammation of the liver (hepatitis), jaundice
- severe diarrhoea
Warning & Precautions

Pregnancy
Monitoring requiredAUGMENTIN DUO ORAL SUSPENSION should be used with caution in pregnant women only if it is considered necessary.

Breastfeeding
Use with CautionAUGMENTIN DUO ORAL SUSPENSION should be used with caution in breastfeeding women.

Kidney
Consult your doctorAUGMENTIN DUO ORAL SUSPENSION is not recommended for use if you have a history of amoxicillin-clavulanate-associated jaundice/hepatic dysfunction. It should be used with caution in patients with hepatic impairment.

Liver
Use with CautionAUGMENTIN DUO ORAL SUSPENSION should be used with caution in patients with renal impairment.

Allergy
ContraindicatedDo not take AUGMENTIN DUO ORAL SUSPENSION if you have a history of hypersensitivity to beta-lactams, including penicillin and cephalosporins, or any other ingredients of this medicine.

Use In Pediatrics
Use with CautionAUGMENTIN DUO ORAL SUSPENSION should be used with caution in children (below 12 years).

Use In Geriatrics
Use with CautionAUGMENTIN DUO ORAL SUSPENSION should be used with caution in elderly patients (above 50 years).
Interactions
A. Drug-Drug Interactions:
Before taking AUGMENTIN DUO ORAL SUSPENSION, inform your doctor if you are taking any of the following medicines:
- medicine used to manage gout Ex. allopurinol, probenecid
- medicine used to delay blood clotting, Ex. warfarin, acenocoumarol
- mycophenolate mofetil (a medicine used to manage organ rejection after an organ transplant)
- contraceptives (medicines used to manage conception) Ex. oestrogen
Overdosage:
If you or anyone else accidentally takes too much of AUGMENTIN DUO ORAL SUSPENSION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are gastrointestinal symptoms (including heartburn, indigestion, bloating, and constipation), fluid and electrolyte disturbance, and amoxicillin crystalluria, which may lead to renal failure in some cases.
Synopsis
Drug | : | Amoxicillin, Clavulanic Acid |
Pharmacological Category | : | Penicillins and Beta-Lactamase Inhibitors |
Therapeutic Indication | : | Bacterial infections |
Dosage Forms | : | Tablet, Capsule, Sachet, Dry Syrup, Suspension, Syrup, Tablet, Capsule, Sachet, Dry Syrup, Suspension, Syrup, Drops, Injections |
FAQs About AUGMENTIN DUO ORAL SUSPENSION
Q: What AUGMENTIN DUO ORAL SUSPENSION is used for?
A: AUGMENTIN DUO ORAL SUSPENSION is used for managing bacterial infections including middle ear & sinus infections, respiratory tract infections, genital tract infections, urinary tract infections, skin & soft tissue infections such as dental infections, bone & joint infections, septic abortion (any abortion complicated by uterine infection), and abdominal infections.
Q: What happens if you take more AUGMENTIN DUO ORAL SUSPENSION than your required dose?
A: If you or anyone else accidentally takes too much of AUGMENTIN DUO ORAL SUSPENSION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are gastrointestinal symptoms (including heartburn, indigestion, bloating, and constipation).
Q: What side effects are seen with AUGMENTIN DUO ORAL SUSPENSION?
A: The common side effects associated with the use of AUGMENTIN DUO ORAL SUSPENSION are diarrhea, thrush (fungal infection in the vagina, skin folds, or mouth), nausea, and vomiting. Contact your doctor immediately if any of the symptoms worsen.
Q: Who should avoid taking AUGMENTIN DUO ORAL SUSPENSION?
A: Do not take AUGMENTIN DUO ORAL SUSPENSION if you are allergic to amoxicillin, clavulanic acid, penicillin, or any antibiotic. It is not recommended for use if you have liver problems or jaundice upon taking an antibiotic or amoxicillin-clavulanate.
Q: Is AUGMENTIN DUO ORAL SUSPENSION safe to use in children?
A: AUGMENTIN DUO ORAL SUSPENSION should be used with caution in children (below 12 years). Children (aged 6 years or below) should be managed with oral suspension or sachets containing amoxicillin and clavulanic acid. Consult your doctor before taking AUGMENTIN DUO ORAL SUSPENSION.
Q: How does AUGMENTIN DUO ORAL SUSPENSION work?
A: AUGMENTIN DUO ORAL SUSPENSION helps in managing bacterial infection where amoxicillin is a penicillin that works by inhibiting the enzymes that help in the synthesis of an integral structural component of the bacterial cell wall whereas clavulanic acid is a beta-lactam (structurally related to penicillin) that works by inactivating an enzyme, namely beta-lactamase, thereby managing the inactivation of amoxicillin.
Q: Is AUGMENTIN DUO ORAL SUSPENSION safe for kidneys?
A: AUGMENTIN DUO ORAL SUSPENSION should be used with caution in patients with renal impairment or kidney problems. Consult your doctor before taking it.
Q: What if I forget to take AUGMENTIN DUO ORAL SUSPENSION dose?
A: If you forgot to take AUGMENTIN DUO ORAL SUSPENSION dose, take it as early as possible. Avoid taking the next dose too soon. Wait for about 4 hours before taking the scheduled next dose. Consult your doctor before taking AUGMENTIN DUO ORAL SUSPENSION.
Q: When to stop taking AUGMENTIN DUO ORAL SUSPENSION?
A: Do not stop taking AUGMENTIN DUO ORAL SUSPENSION without thoroughly discussing it with your doctor until the management course is completed, even if you start feeling better. This is because if some bacteria survive due to incomplete medication, they may relapse into the infection.
Q: Is AUGMENTIN DUO ORAL SUSPENSION safe to use in liver patients?
A: AUGMENTIN DUO ORAL SUSPENSION is not recommended for use if you have liver problems or jaundice upon taking an antibiotic or amoxicillin-clavulanate. It should be used with caution in patients with hepatic impairment or liver problems. Consult your doctor before taking AUGMENTIN DUO ORAL SUSPENSION.
References
1. KD Tripathi. Beta-Lactam Antibiotics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 723.
2. Justin Evans, Maryam Hannoodee, Micah Wittler. Amoxicillin Clavulanate. NIH National Library of Medicine. National Centre for Biotechnology Information. Stat Pearls [Internet]. December 2021. [Assessed on 7th October 2024] click here
3. GSK group of companies. Augmentin. [Revised in December 2017] [Assessed on 7th October 2024] click here
4. Micro Labs Ltd. Erox CV 228.5 Dry Syrup. [Assessed on 7th October 2024] click here
5. Micro Labs Ltd. Erox CV 457 Dry Syrup. [Assessed on 7th October 2024] click here
6. Geno Pharmaceuticals Pvt. Ltd. Genomox-CV. [Assessed on 7th October 2024] click here
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