Aprovel 150mg Tablet 14'S
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Introduction About APROVEL 150MG TABLET
APROVEL 150MG TABLET contains Irbesartan which belongs to the group of medicines called Angiotensin-II receptor antagonists. It is used to manage high blood pressure (essential hypertension) and protects the kidney in patients with high blood pressure, type 2 diabetes, and laboratory evidence of impaired kidney function.
Blood pressure is the pressure of blood pushing against the walls of your arteries. Arteries carry blood from your heart to other parts of your body. Hypertension (high blood pressure) is when the pressure in your blood vessels is too high. APROVEL 150MG TABLET is not recommended for use in patients with diabetes or impaired kidney function. APROVEL 150MG TABLET is generally not recommended for use among pregnant and breastfeeding women.
APROVEL 150MG TABLET is not recommended for use in children and adolescents (under 18 years of age). APROVEL 150MG TABLET should be used with caution in elderly patients (aged above 75 years). Consult your doctor before taking. The most common side effects of taking APROVEL 150MG TABLET are dizziness, vomiting and feeling tired (fatigue). Contact your doctor if any of the above side effects worsen or persists for a longer duration.
Uses Of APROVEL 150MG TABLET
It is used to:
- manage hypertension (essential hypertension)
- protect the kidney in patients with high blood pressure, type 2 diabetes, and laboratory evidence of impaired kidney function
How APROVEL 150MG TABLET Works
APROVEL 150MG TABLET works by relaxing the blood vessel by blocking the action of a chemical (angiotensin-II) that usually makes blood vessels tighter. This lowers the blood pressure, which allows the blood to flow more smoothly to different organs and the heart to pump more efficiently.
How to use APROVEL 150MG TABLET
Take APROVEL 150MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Side Effects Of APROVEL 150MG TABLET
Common
- dizziness
- vomiting
- feeling tired (fatigue)
- dizziness when getting up from a sitting or lying position
- low blood pressure when getting up from a lying or sitting position
- pain in joints or muscles
Uncommon
- heart beating faster (heart rate increased)
- flushing
- cough
- diarrhea
- indigestion/heartburn
- sexual dysfunction
- chest pain
Stop taking APROVEL 150MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- serious allergic reaction (symptoms such as itchy red rash, feeling dizzy or faint, swelling of the face, lips, and/or tongue which may cause difficulty breathing)
- yellowing of the skin and whites of the eyes, severe upper stomach pain, and feeling and being sick (liver problems)
- raised purple spots and flat red areas caused by inflammation of small blood vessels
- passing urine more often, in greater amounts which is pale in color, or straining or being unable
- to pass urine or less often, which may be darker in color or may even be bloody (kidney problems)
How To Manage Side Effects
Diarrhea
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
Nausea And Vomiting
Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods.
Warning & Precautions
Pregnancy
ContraindicatedAPROVEL 150MG TABLET is not recommended in early pregnancy and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy. Consult your doctor before taking it.
Breastfeeding
ContraindicatedAPROVEL 150MG TABLET is not recommended for use in breastfeeding women as it may pass through breast milk. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionAPROVEL 150MG TABLET is unlikely to affect your ability to drive or use machines. However, occasionally dizziness or weariness may occur during management of high blood pressure. Consult your doctor before taking it.
Kidney
Consult your doctorAPROVEL 150MG TABLET is not recommended for use if you have impaired kidney function. It should be used with caution in patients with kidney problems, including narrowing of the kidney artery or have had a kidney transplant. Consult your doctor before taking.
Allergy
ContraindicatedDo not take APROVEL 150MG TABLET if you are allergic to Irbesartan or any of the other ingredients of this medicine.
Heart Disease
Use with CautionAPROVEL 150MG TABLET should be used with caution if you have heart problems, including a narrowing of the valves in the heart, an enlarged heart muscle or a weakness of the heart muscle (heart failure) or narrowing of the heart blood vessels. Consult your doctor before taking.
Use In Pediatrics
ContraindicatedAPROVEL 150MG TABLET is not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking.
Use In Geriatrics
Use with CautionAPROVEL 150MG TABLET should be used with caution in elderly patients (aged above 75 years). Consult your doctor before taking.
Others
APROVEL 150MG TABLET is not recommended for use if you:
- diabetes
Before taking APROVEL 150MG TABLET, inform your doctor if you:
- have or had, or during management have, excessive vomiting (being sick) or diarrhea
- develop low blood sugar levels (symptoms may include sweating, weakness, hunger, dizziness, trembling, headache, flushing or paleness, numbness, having a fast, pounding heartbeat)
- have primary aldosteronism (high production of the hormone aldosterone)
- are going to have an operation (surgery) or be given anesthetics
- have low sodium diet
Interactions
A. Drug-Drug interactions:
Before taking APROVEL 150MG TABLET, inform your doctor if you are taking any of the following medicine:
- medicines used to manage high blood pressure (Ex. enalapril, lisinopril, ramipril, aliskiren)
- water tablets (Ex. spironolactone, furosemide)
Overdosage:
If you or anyone else accidentally takes too much of APROVEL 150MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are feeling dizzy and/or feeling the heart beating faster or slower.
Synopsis
| Drug | : | Irbesartan |
| Pharmacological Category | : | Angiotensin-II receptor antagonists |
| Therapeutic Indication | : | Hypertension, Protects the kidney in patients with high blood pressure, type 2 diabetes, and laboratory evidence of impaired kidney function |
| Dosage Forms | : | Tablet |
More Information
- Keep APROVEL 150MG TABLET out of reach of children
- Store at a room temperature
FAQs About APROVEL 150MG TABLET
Q: What is the use of APROVEL 150MG TABLET?
A: APROVEL 150MG TABLET used to manage high blood pressure (essential hypertension) and protects the kidney in patients with high blood pressure, type 2 diabetes, and laboratory evidence of impaired kidney function.
Q: Can I use APROVEL 150MG TABLET along with ACE inhibitors?
A: APROVEL 150MG TABLET should not be taken along with ACE inhibitors, as they may cause side effects. Consult your doctor before taking it.
Q: What are the symptoms of overdosage of APROVEL 150MG TABLET?
A: Symptoms of overdose are feeling dizzy and/or feeling the heart beating faster or slower. If you or anyone else accidentally takes too much of APROVEL 150MG TABLET, consult your doctor immediately or visit the nearby hospital.
Q: How should I take APROVEL 150MG TABLET?
A: Take APROVEL 150MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Q: When not to take APROVEL 150MG TABLET?
A: APROVEL 150MG TABLET should not be taken if you have diabetes or impaired kidney function. Proper dose adjustment and careful monitoring are required in such patients. Consult your doctor before taking.
Q: Is APROVEL 150MG TABLET cause dizziness?
A: One of the most common side effects of taking APROVEL 150MG TABLET is dizziness. However, it does not affect every individual. Contact your doctor if any of the symptoms worsen.
References
1. Thomas Eschenhagen. Treatment of Hypertension. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018. Page – 507-526.
2. Valentina Forni, Grégoire Wuerzner, Menno Pruijm, and Michel Burnier. Long-term use and tolerability of irbesartan for control of hypertension. Journal of Integrated Blood Pressure Control. April 2011. [Accessed on 31st May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172075/
3. Hubert G. Pouleur. clinical Overview of Irbesartan: A New Angiotensin II Receptor Antagonist. American Journal of Hypertension. December 1997. [Accessed on 31st May 2022] https://academic.oup.com/ajh/article/10/S9/318S/131622
4. Noriaki Nagai, Fumihiko Ogata, Ayari Ike, Yurisa Shimomae, Hanano Osako, Yosuke Nakazawa, Naoki Yamamoto and Naohito Kawasaki. Oral Formulation Based on Irbesartan Nanocrystals Improve Drug Solubility, Absorbability, and Efficacy. February 2022. [Accessed on 31st May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875686/pdf/pharmaceutics-14-00387.pdf
5. Mylan Products Ltd. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 31st May 2022] https://www.medicines.org.uk/emc/files/pil.11833.pdf
Useful Diagnostic Tests
- Kidney function test
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