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Introduction About AMLOPIN 5MG TABLET
AMLOPIN 5MG TABLET is a medication used primarily for the management of high blood pressure (hypertension) and angina (Prinzmetal’s or variant angina). The active ingredient, Amlodipine , is a calcium channel blocker that helps relax blood vessels, reducing strain on the heart and lowering blood pressure and chest pain.
You can take AMLOPIN 5MG TABLET at any time of the day, with or without food. For the best results, try to take it around the same time every day. Always follow your doctor’s instructions and take the medication for as long as prescribed, even if you feel fine. Sudden discontinuation may worsen your condition, as high blood pressure often has no visible symptoms.
Complement your therapy with regular physical activity, a healthy diet, and weight management to maintain optimal blood pressure levels.
Before taking AMLOPIN 5MG TABLET, inform your doctor if you have any liver, heart, or kidney problems, as this may affect your dosage. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Always share details about any other medications you are taking, especially those for blood pressure or heart conditions, as interactions could affect the efficacy of AMLOPIN 5MG TABLET.
Regular monitoring of blood pressure is essential to ensure the medication is working as intended and to adjust the dosage if needed. The most common side effects of taking AMLOPIN 5MG TABLET are headache, edema (swelling), fatigue, nausea, abdominal pain, and drowsiness. If these symptoms persist or worsen, consult your doctor.
Uses Of AMLOPIN 5MG TABLET
- high blood pressure (hypertension)
- Angina (prinzmetal’s or variant angina)
Benefits of AMLOPIN 5MG TABLET
Benefits of AMLOPIN 5MG TABLET in Hypertension:
AMLOPIN 5MG TABLET works by relaxing and widening blood vessels, which helps to reduce blood pressure. It improves overall circulation, making it easier for the heart to pump blood, thus effectively managing high blood pressure and reducing the risk of heart disease and stroke.
Benefits of AMLOPIN 5MG TABLET in Angina:
By improving blood flow and reducing cholesterol plaque build-up in arteries, AMLOPIN 5MG TABLET helps reduce angina (heart-related chest pain) caused by blocked or narrowed coronary arteries. This reduces the frequency and intensity of chest pain episodes, allowing for improved quality of life for patients with heart disease.
Other Benefits:
By controlling blood pressure, AMLOPIN 5MG TABLET helps reduce the chances of heart attacks, strokes, and other serious cardiovascular events in patients suffering from hypertension and angina.
How AMLOPIN 5MG TABLET Works
AMLOPIN 5MG TABLET contains Amlodipine. In patients with high blood pressure it works by relaxing blood vessels, so that blood passes through them more easily. In patients with angina it works by improving blood supply to the heart muscle which then receives more oxygen and as a result chest pain is managed. This medicine does not provide immediate relief of chest pain from angina.
How to use AMLOPIN 5MG TABLET
- Take AMLOPIN 5MG TABLET exactly as prescribed by your healthcare provider. It is usually taken once a day, with or without food. For best results, try to take it at the same time each day.
- Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Recommended Dosage:
- The typical starting dose of Amlodipine is 5mg per day. Depending on your condition and response to the medication, your doctor may adjust the dose.
- Always follow your doctor's instructions regarding the dose and duration of treatment for optimal results in managing cholesterol levels and cardiovascular health.
What if I forgot to take AMLOPIN 5MG TABLET
- If you miss a dose of AMLOPIN 5MG TABLET, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose. Do not double the dose to make up for the missed one, as this may lead to side effects or complications.
Overdose
Symptoms of Overdosage: Overdosing on AMLOPIN 5MG TABLET may cause symptoms such as dizziness, confusion, muscle pain, or weakness. If you suspect an overdose, seek immediate medical attention or contact your healthcare provider.
Side Effects Of AMLOPIN 5MG TABLET
Like all medicines, AMLOPIN 5MG TABLET may cause certain side effects although not everybody gets them
Common Side Effects of AMLOPIN 5MG TABLET:
- Swelling of ankles
- headache, dizziness
- sleepiness, tiredness, muscle cramps
- palpitations (awareness of heart beat)
- flushing
- abdominal pain, diarrhoea, constipation, indigestion
- nausea
- altered bowel habits
- visual disturbances, double vision
- vomiting
- joint or muscle pain, back pain
When to consult your doctor?
Stop taking the medicine, and contact your doctor immediately if you experience any of the following side effects:
- sudden wheeziness, chest pain, shortness of breath or difficulty in breathing
- swelling of the tongue and throat which causes great difficulty breathing
- severe skin reactions including an intense skin rash, hives, reddening of the skin over your whole body, severe itching, blistering, peeling and swelling of the skin, inflammation of mucous membranes (stevens-johnson syndrome, toxic epidermal necrolysis) or other allergic reactions
How To Manage Side Effects
Dizziness Or Drowsiness
To manage dizziness caused by AMLOPIN 5MG TABLET, follow the below mentioned tips:
- Lie Down or Sit Down: If you feel dizzy, sit or lie down immediately to avoid falls or injury. Rest until the dizziness passes, and get up slowly when you're ready to stand.
- Stay Hydrated: Drink plenty of water throughout the day to help maintain your blood pressure and prevent dehydration, which can worsen dizziness.
- Avoid Sudden Movements: Stand up slowly from sitting or lying positions, and avoid quick head movements to reduce the risk of dizziness or lightheadedness.
These simple steps can help manage dizziness caused by amlodipine while ensuring your safety and comfort.
Warning & Precautions
Pregnancy
Consult your doctorThe safety of AMLOPIN 5MG TABLET in human pregnancy has not been established. If you think you might be pregnant, or are planning to get pregnant, consult your doctor before taking the medicine.
Breastfeeding
Consult your doctorAMLOPIN 5MG TABLET has been shown to pass into breast milk in small amounts. If you are breast-feeding or about to start breast-feeding, consult your doctor before taking the medicine.
Driving and Using Machines
Use with CautionDo not drive or handle any machines if you experience sickness, dizziness or tiredness or headache after taking AMLOPIN 5MG TABLET.
Liver
Use with CautionAMLOPIN 5MG TABLET should be used with caution in patients with liver disease.
Allergy
ContraindicatedDo not take AMLOPIN 5MG TABLET if you are allergic to Amlodipine or any other ingredients of this medicine.
Heart Disease
Consult your doctorAMLOPIN 5MG TABLET is not recommended if you have narrowing of the aortic heart valve (aortic stenosis) or cardiogenic shock or suffer from heart failure after a heart attack. It should be used with caution if you have recent heart attack or heart failure, severe increase in blood pressure (hypertensive crisis).
Use In Pediatrics
Consult your doctorAMLOPIN 5MG TABLET has not been studied in children under the age of 6 years. It should only be used for hypertension in children and adolescents from 6 years to 17 years of age.
Use In Geriatrics
Use with CautionAMLOPIN 5MG TABLET should be used with caution in elderly patients (aged 65 years and above). Dosage will be adjusted accordingly.
Who should not take [GBNKEYWORD
AMLOPIN 5MG TABLET is not recommended for use if you:
- have signs of an allergic reaction may include itching, reddening of the skin or difficulty in breathing
- have severe low blood pressure (hypotension)
Safety Advice
Expert Advice to maximise the effects of AMLOPIN 5MG TABLET:
To get the best results from AMLOPIN 5MG TABLET, here are some expert tips for effective management of hypertension and angina:
- Take Consistently at the Same Time: For optimal results, take AMLOPIN 5MG TABLET at the same time every day to maintain a steady level of the medication in your body.
- Follow a Healthy Diet: Incorporate a heart-healthy diet, rich in fruits, vegetables, and whole grains, while limiting salt and processed foods to help lower blood pressure and support cardiovascular health.
- Stay Active: Regular physical activity, such as walking or light exercise, can enhance the effectiveness of AMLOPIN 5MG TABLET by improving circulation and helping to maintain a healthy weight.
- Monitor Your Blood Pressure: Regularly check your blood pressure to ensure that the medication is effectively controlling it. This also helps to adjust the dosage if needed.
- Avoid Alcohol and Smoking: Limit alcohol consumption and quit smoking to prevent interference with the medication's effects and improve overall heart health.
- Follow Doctor’s Instructions: Always adhere to your doctor’s advice regarding dosage, lifestyle changes, and follow-up appointments to ensure maximum benefit from AMLOPIN 5MG TABLET.
Diet and Lifestyle Advice
When taking AMLOPIN 5MG TABLET for managing high blood pressure (hypertension) or angina (chest pain), combining it with healthy lifestyle choices and a balanced diet can significantly enhance the medication's effectiveness. Here are some expert tips:
1. Follow a Heart-Healthy Diet:
- Limit Salt Intake: Reduce your sodium intake to help manage blood pressure. Aim for less than 2,300 mg of sodium per day, or lower if advised by your doctor.
- Increase Fruits and Vegetables: Include plenty of potassium-rich foods like bananas, oranges, leafy greens, and sweet potatoes to help regulate blood pressure.
- Opt for Whole Grains: Choose whole grains like oats, brown rice, and whole wheat bread instead of refined grains to improve heart health and control cholesterol levels.
- Healthy Fats: Focus on unsaturated fats (found in olive oil, nuts, and avocados) and avoid trans fats and excessive saturated fats that can increase cholesterol.
2. Maintain a Healthy Weight:
- Exercise Regularly: Aim for at least 30 minutes of moderate exercise (like walking or cycling) most days of the week. Regular physical activity helps reduce blood pressure, improve heart function, and maintain a healthy weight.
- Weight Management: If you are overweight, losing even a small amount of weight can significantly help in lowering blood pressure and improving heart health.
3. Limit Alcohol and Quit Smoking
- Limit Alcohol Consumption: Drinking alcohol in excess can increase blood pressure and reduce the effectiveness of medications like AMLOPIN 5MG TABLET. Stick to the recommended limits: up to one drink per day for women and two drinks per day for men.
- Quit Smoking: Smoking can increase the risk of heart disease and complications associated with hypertension. Quitting smoking improves overall heart health and reduces blood pressure.
4. Monitor Your Blood Pressure Regularly
- Keep track of your blood pressure readings at home to ensure that your AMLOPIN 5MG TABLET dosage is working effectively. Regular monitoring can help adjust treatment if needed.
5. Manage Stress
- Chronic stress can contribute to high blood pressure and heart-related issues. Incorporate stress-reducing techniques like yoga, meditation, or deep breathing exercises into your daily routine to help manage blood pressure.
6. Stay Hydrated
- Drink Plenty of Water: Staying hydrated helps regulate blood pressure and supports overall cardiovascular health.
Drug - Drug interaction
1. CYP3A4 Inhibitors (e.g., Ketoconazole, Itraconazole, Ritonavir)
Effect: These medications can increase the blood levels of Amlodipine, leading to a higher risk of side effects like severe low blood pressure (hypotension), dizziness, or swelling in the ankles and feet.
2. Nitrates (e.g., Nitroglycerin, Isosorbide Dinitrate)
Effect: Combining Amlodipine with nitrates can result in severe hypotension (low blood pressure), causing dizziness, fainting, or even shock, especially when used in patients with heart disease.
3. Alpha-blockers (e.g., Doxazosin, Prazosin)
Effect: When used together, Amlodipine can intensify the blood pressure-lowering effects of alpha-blockers, leading to excessive hypotension and an increased risk of dizziness or fainting, particularly when standing up.
Other drug-drug interactions are:
- Antibiotics (Ex. rifampicin, erythromycin, clarithromycin)
- St. John’s Wort (Ex. hypericum perforatum)
- Heart medicines (Ex. verapamil, diltiazem)
- Skeletal muscle relaxant (Ex. Dantrolene)
- Immunosuppressants (Ex. tacrolimus, sirolimus, temsirolimus, everolimus, ciclosporin)
- HMG-CoA reductase inhibitors (Ex. Simvastatin)
Drug - Food interaction
- Grapefruit juice and grapefruit is not recommended while taking the medicine. This is because grapefruit and grapefruit juice can lead to an increase in the blood levels of the active ingredient amlodipine, which can cause an unpredictable increase in the blood pressure lowering effect of the medicine.
Synopsis
| Drug | : | Amlodipine |
| Pharmacological Category | : | Calcium Channel Blockers |
| Therapeutic Indication | : | Hypertension, Angina |
| Dosage Forms | : | Tablet |
FAQs About AMLOPIN 5MG TABLET
Q: What is AMLOPIN 5MG TABLET used for?
A: AMLOPIN 5MG TABLET is primarily used for managing high blood pressure (hypertension) and angina (chest pain). It helps lower blood pressure, relax blood vessels, and reduce the heart's workload, which prevents heart attacks and strokes.
Q: How does AMLOPIN 5MG TABLET work?
A: AMLOPIN 5MG TABLET is a calcium channel blocker that works by relaxing the blood vessels and improving blood flow. This helps lower blood pressure and prevent chest pain (angina). It also reduces the strain on the heart by lowering the heart's workload.
Q: How should I take AMLOPIN 5MG TABLET?
A: Take AMLOPIN 5MG TABLET once daily, with or without food, at the same time each day. Swallow the tablet whole with a glass of water. Avoid breaking or chewing the tablet. Follow your doctor's prescribed dosage instructions.
Q: What are the common side effects of AMLOPIN 5MG TABLET?
A: Common side effects of AMLOPIN 5MG TABLET include headache, dizziness, swelling of the ankles, fatigue, and nausea. If you experience persistent or severe side effects, consult your healthcare provider.
Q: Can AMLOPIN 5MG TABLET cause weight gain?
A: AMLOPIN 5MG TABLET may cause swelling (edema) in the ankles and feet, which can sometimes lead to weight gain. To manage this, it's recommended to maintain a healthy diet and engage in regular physical activity.
Q: Can I take AMLOPIN 5MG TABLET with other medications?
A: AMLOPIN 5MG TABLET may interact with other medications, especially those used for blood pressure or heart conditions. Always inform your doctor about all the medications you are taking to avoid potential interactions.
Q: Is AMLOPIN 5MG TABLET safe to take during pregnancy or breastfeeding?
A: or breastfeeding women should consult their doctor before taking AMLOPIN 5MG TABLET. While it's classified as a Category C medication, meaning risks cannot be ruled out, a healthcare provider can determine if the benefits outweigh potential risks.
Q: What should I do if I miss a dose of AMLOPIN 5MG TABLET?
A: If you miss a dose of AMLOPIN 5MG TABLET, take it as soon as you remember, unless it’s almost time for your next dose. Do not take a double dose to make up for the missed one, as this could increase the risk of side effects.
Q: Can AMLOPIN 5MG TABLET cause dizziness?
A: Yes, dizziness is a common side effect of AMLOPIN 5MG TABLET. To minimize the risk of dizziness, avoid sudden changes in position, such as standing up quickly, and ensure you stay hydrated. If dizziness persists, consult your doctor.
Q: How can I manage the swelling in my ankles caused by AMLOPIN 5MG TABLET?
A: To manage swelling (edema) in the ankles caused by AMLOPIN 5MG TABLET, elevate your feet whenever possible, reduce your salt intake, and engage in regular physical activity. If the swelling continues or worsens, contact your healthcare provider.
Q: What precautions should be followed while taking AMLOPIN 5MG TABLET?
A: Before taking the medicine, inform your doctor if you have any liver problems. You must also inform your doctor if you have severe high or low blood pressure or other heart problems (such as narrowing of the arteries, cardiogenic shock, or a recent heart attack). Regularly visit your doctor and take all the necessary blood tests recommended by your doctor without fail.
Q: Can I stop taking AMLOPIN 5MG TABLET once my symptoms subside?
A: No. Do not stop taking AMLOPIN 5MG TABLET without consulting your doctor. As hypertension is a chronic condition, long-term management may be necessary to control its symptoms. Therefore, take the medicine as advised by your doctor for the stipulated duration. Premature discontinuation of therapy may increase the blood pressure once again.
References
1. KD. Tripathi. Antianginal and other Anti-ischaemic Drugs & Drugs Affecting Renin Angiotensin System. Eighth edition. June 2018. Page-596 & 536.
2. C Venkata S Ram, Baby Shalini Muppalla, Sarvepalli Vijaya Parthasaradhi, Gajjela Praveen Kumar, Saumitra Ray, Uday Jadhav, J P S Sawhney, Govindan Unni, Nagaraj Desai, Members of the TelCom Study Group. Achieving the Latest American Heart Association and American College of Cardiology Therapeutic Goals for Hypertension With Combination Therapy and Its Effects on Blood Pressure and Central Hemodynamic Parameters. NIH National Library of Medicine. National Centre for Biotechnology Information. Pubmed.gov. April 2022. [Accessed on 8th July 2025] 
3. Zentiva Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised on November 2023] [Accessed on 8th July 2025] 
4. Dr. Reddy’s Laboratories (UK) Ltd. [Revised on February 2024] [Accessed on 8th July 2025]
5. Cipla (EU) Limited. [Revised on May 2015] [Accessed on 8th July 2025]
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