AMICET PLUS Tablet 10's

INTRODUCTION

AMICET PLUS TABLET is a combination of Ambroxol, Levocetirizine and Phenylephrine which belongs to the group of medicines called Mucolytic, Antihistamines and Nasal decongestants. It is used to treat productive cough, bronchitis (inflammation of bronchioles), asthma (narrowing of airways causing difficulty in breathing), emphysema (destruction of air spaces of lungs) and other chronic inflammatory conditions.

AMICET PLUS TABLET is not recommended for use in patients with severe kidney disease. AMICET PLUS TABLET should be used with caution in patients with heart disease high blood pressure, thyroid disease, diabetes. Contact your doctor before taking it.

AMICET PLUS TABLET is generally not recommended for use during the first trimester of pregnancy and in breastfeeding women. Contact your doctor before taking it.

AMICET PLUS TABLET is not recommended for use in children under 12 years of age. AMICET PLUS TABLET should be used with caution in elderly patients. Contact your doctor before taking it.

The most common side effects of taking AMICET PLUS TABLET are drowsiness, tiredness, nausea, vomiting, diarrhea, indigestion, heartburn or bloating etc. Contact your physician if any of the symptoms worsen.

USES OF AMICET PLUS TABLET

Treats:

• Productive cough
• Bronchitis
• Asthma
• Emphysema

HOW AMICET PLUS TABLET WORKS

AMICET PLUS TABLET helps to treat productive cough, where Ambroxol is a mucolytic which thins and breaks the phlegm, making it easier to cough out. Levocetirizine is an Antihistamine blocks the binding of histamine (responsible for allergic reactions such as sneezing, watery and itchy eyes and runny nose) to Histamine H1receptors, thus preventing allergic reactions and Phenylephrine is a Nasal decongestant works by reducing swelling of the blood vessel in nasal passages, thus makes it easier to breathe.

DIRECTIONS FOR USE

Take AMICET PLUS TABLET as directed by your physician. Swallow the medicine with a glass of water and do not crush or chew the medicine. Your doctor will decide the correct dose, duration and frequency for you depending on your age, body weight and disease condition.

SIDE EFFECTS OF AMICET PLUS TABLET

HOW TO MANAGE SIDE EFFECTS

Diarrhea

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Do not take any medicine on your own for treating diarrhoea. Contact your doctor if your diarrhoea did not improve.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling drowsy. Do not drink alcohol, as it can aggravate your drowsiness. Contact your doctor if your drowsiness did not improve.

Dry Mouth

Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your doctor if the dry mouth gets worse.

Indigestion

Eat smaller and frequent meals. Eat and drink slowly and exercise regularly. If the indigestion does not improve, contact your doctor.

Nausea And Vomiting

Take AMICET PLUS TABLET, with or just after a meal. Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if your nausea and vomiting did not improve.

Skin Rash Or Itching

Avoid hot bath because hot water can irritate your skin further. Do not scratch the affected area. Use sunscreen and wear protective clothing while going outside. Use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if your rashes worsen.

Stomach Pain

Try to have smaller meals but take frequently. Keep a heat pad on your stomach. Do not self-treat and contact your doctor if the stomach pain did not improve.

WARNING & PRECAUTIONS

PREGNANCY

Monitoring required

AMICET PLUS TABLET is generally not recommended for use during the first trimester of pregnancy. Therefore, contact your doctor before taking it.

BREASTFEEDING

Contraindicated

AMICET PLUS TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking it.

DRIVING AND USING MACHINES

Use with Caution

AMICET PLUS TABLET may cause sleepiness, fatigue and weakness. Do not drive or operate any machine after taking this medicine.

ALCOHOL

Consult your doctor

Avoid consumption of alcohol while taking AMICET PLUS TABLET as it may lead to unwanted effects like decrease in alertness and impairment of performance.

KIDNEY

Contraindicated

AMICET PLUS TABLET is not recommended for use in patients with severe kidney disease or undergoing haemodialysis. Contact your doctor before taking it.

LIVER

Consult your doctor

AMICET PLUS TABLET should be used in patients with severe liver disease only after consulting your doctor. Therefore, contact your doctor before taking it.

ALLERGY

Contraindicated

Do not take AMICET PLUS TABLET if you are allergic to ambroxol, levocetirizine or to cetirizine, hydroxyzine and phenylephrine or to other ingredients of this medicine.

HEART DISEASE

Use with Caution

AMICET PLUS TABLET should be used with caution in patients with heart disease high blood pressure. Contact your doctor before taking it.

INTERACTIONS

A. Drug-Drug interactions:

Before taking AMICET PLUS TABLET, inform your doctor if you are taking any of the following medicine:

• central nervous system depressants Ex. lorazepam, diazepam (medicines used for anxiety, fits, panic disorders)
• theophylline (used to treat asthma)
• ritonavir (used for HIV infection)
• monoamine oxidase inhibitor Ex. selegiline (medicines used for depression, parkinson’s disease)

Overdosage:

If you or anyone else accidentally take too much of AMICET PLUS TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage may include drowsiness, agitation and restlessness.

SYNOPSIS

MORE INFORMATION

• Keep AMICET PLUS TABLET out of the sight and reach of children.
• Store AMICET PLUS TABLET below 30°C

FAQs ABOUT AMICET PLUS TABLET

Q: How fast does AMICET PLUS TABLET works?

A: AMICET PLUS TABLET starts to work within 30 minutes of oral administration and the effect persists for 6 to 12 hours. Contact your doctor if your symptoms did not improve.

Q: What precautions have to be taken while using AMICET PLUS TABLET?

A: Before taking AMICET PLUS TABLET inform your doctor if you have severe liver disease, heart disease high blood pressure, difficulty in urination due to spinal cord lesion, prostate gland enlargement, thyroid disease and diabetes. Contact your doctor before taking AMICET PLUS TABLET.

Q: Is AMICET PLUS TABLET safe in pregnancy?

A: No. AMICET PLUS TABLET is generally not recommended for use during the first trimester of pregnancy. Inform your doctor if you are pregnant or planning for pregnancy before taking this medicine.

Q: What are the side effects of taking AMICET PLUS TABLET?

A: The most common side effects of taking AMICET PLUS TABLET are drowsiness, tiredness, nausea, vomiting, diarrhea, indigestion, heartburn, bloating, abdominal pain and dry mouth or dry throat. Contact your physician if any of the symptoms worsen.

Q: Does AMICET PLUS TABLET cause sleepiness?

A: Yes. AMICET PLUS TABLET may cause sleepiness. Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling sleepy. Do not consume alcohol, as it increases sleepiness. Contact your doctor if sleepiness did not improve.

REFERENCES

1. K.D. Tripathi. Drugs for Cough and Bronchial Asthma, Histamine and Antihistaminics, Adrenergic System and Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 219, 167, 135.

2. Hair PI, Scott L J. Levocetirizine: a review of its use in the management of allergic rhinitis and skin allergies. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed.gov 2006. [Accessed on 22nd July 2022]. https://pubmed.ncbi.nlm.nih.gov/16740020/

3. Bethesda (MD). Ambroxol. NIH National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 22nd July 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Ambroxol

4. Actavis Group PTC ehf. Ambroxol. [Revised in 2020] [Accessed on 22nd July 2022]. https://file.wuxuwang.com/hma/DK_H_2363_002_FinalSPC.pdf

5. GSK limited. Levocetirizine. [Revised in April 2016] [Accessed on 22nd July 2022]. https://gskpro.com/content/dam/global/hcpportal/en_NG/PDF/Home/Products/xyzal/xyzal_prescribing_information.pdf

6. Levocetirizine tablet. Daily Med: National Library of Medicine: National Institute of Health. [Revised in December 2021] [Accessed on 22nd July 2022]. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=717eb542-3a05-485e-be76-3930efb40d33

7. Phenylephrine tablet. Daily Med: National Library of Medicine: National Institute of Health. [Revised in March 2022] [Accessed on 22nd July 2022]. https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=2868f830-3bd7-4c4d-b667-b74950d740ac&type=pdf

8. Phenylephrine tablet. Daily Med: National Library of Medicine: National Institute of Health. [Revised in August 2022] [Accessed on 22nd July 2022]. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0153294d-7f52-4d92-8db8-daeca3e29a3b

9. Amicet Plus tablet (Ambroxol, Levocetirizine and Phenylephrine). Leeford Healthcare Ltd. [Accessed on 22nd July 2022]. https://www.leeford.in/product/544/amicet-plus-tablets

AUTHOR DETAILS

Written By Dr. N. Sai Swaroop, Pharm.D
Last updated on 28 Jan 2023 | 11:42 AM(IST)