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Aldactone 25mg Tablet 15'S

Hypertension
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    Introduction About ALDACTONE 25MG TABLET

    What is Aldactone 25mg Tablet used for?

    Aldactone 25mg Tablet is commonly chosen by individuals who are managing fluid levels in the body. It contains Spironolactone, a potassium-sparing component that works by supporting healthy salt and water balance. It may be part of a broader wellness plan involving regular check-ups, dietary adjustments, or lifestyle management.

    Aldactone 25mg Tablet is typically taken once daily or as directed by your healthcare provider. Taking it after meals may help reduce the chance of stomach discomfort. Always follow your healthcare professional advice for best results.

    Avoid combining with high-potassium foods or supplements unless recommended. Check with your doctor if you are already on other medications, especially diuretics or blood pressure-related tablets. Ideal hydration practices are encouraged during the course of usage.

    Use Aldactone 25mg Tablet during pregnancy or breastfeeding should only be considered if clearly advised by a healthcare provider, as spironolactone may influence hormone levels. Always inform your doctor about any other medications, especially other diuretics, NSAIDs, or hormone-affecting therapies, to avoid interactions.

    It is important to avoid excessive potassium-rich foods or supplements, and space it away (by 2 hours) from iron or calcium tablets for best absorption. Regular monitoring of blood potassium and kidney function is advised while using Aldactone.

    The common side effects may include increased urination, mild dizziness, breast discomfort, or menstrual changes in some individuals. These effects may vary by gender and dosage.

    Key Composition

    Each tablet of Aldactone 25mg contains:

    • Spironolactone - 25 mg as the active ingredient

    Uses Of ALDACTONE 25MG TABLET

    It is used to,

    • manage fluid levels
    • support healthy salt and water balance

    Benefits of ALDACTONE 25MG TABLET

    1. Managing fluid retention

    • Aldactone 25mg Tablet contains spironolactone, which supports the body's natural elimination of excess fluid while helping to maintain healthy potassium levels.

    2. Role in blood pressure regulation

    • Spironolactone is used under medical supervision as part of a broader plan to support mild to moderate blood pressure variations, especially in individuals with underlying fluid imbalance or hormonal sensitivity. It is typically added when first-line medicines are not sufficient or when potassium levels need to be preserved
    • Taking Aldactone 25mg Tablet regularly as prescribed may assist in promoting better vascular stability over time. However, it is crucial to monitor blood pressure and electrolytes regularly while using this product.

    3. Application in Hormonal Imbalances

    • Aldactone is also known for its use in conditions involving hormonal fluctuations, such as certain androgen-related concerns. In such scenarios, spironolactone may be included as part of a personalized medical plan aimed at modulating the effects of androgens

    Who might consider Aldactone 25mg?

    • Adults who are advised to monitor fluid retention
    • Individuals managing their sodium-potassium balance
    • People seeking support for water balance along with other lifestyle measures

    How ALDACTONE 25MG TABLET Works

    What does Aldactone 25mg do in the body?

    • Aldactone 25mg Tablet contains Spironolactone, a potassium-sparing diuretic that helps the body remove excess water and sodium while retaining potassium. It works by blocking the action of a hormone called aldosterone, which is responsible for signaling the kidneys to retain salt and water. By reducing the effect of aldosterone, Aldactone helps the kidneys naturally excrete excess fluid, easing symptoms of fluid buildup such as swelling in the legs, abdomen, or lungs
    • In addition to its role in supporting fluid balance, Aldactone also has mild effects on androgen (male hormone) activity, making it suitable for certain hormone-sensitive conditions under a healthcare provider’s guidance. It is often considered in people who need fluid control without the potassium loss associated with some other water pills

    Key actions of Aldactone 25mg:

    • Helps reduce water retention (edema)
    • Supports blood pressure regulation in specific individuals
    • Maintains potassium balance
    • Assists in managing androgen-related concerns under expert advice

    Is Aldactone a water pill or hormone pill?

    • Aldactone 25mg Tablet is primarily considered a potassium-sparing diuretic, commonly referred to as a “water pill”
    • However, Aldactone also has mild anti-androgenic properties, meaning it can influence certain hormonal pathways, particularly those involving androgens (male hormones)

    Is Aldactone used for fluid retention or hormonal imbalance?

    • For fluid retention: Commonly used to manage swelling, bloating, or excess water buildup
    • For hormonal imbalance: Occasionally advised in specific cases like androgen-related concerns

    How to use ALDACTONE 25MG TABLET

    How to take Aldactone 25mg Tablet?

    • Aldactone 25mg Tablet is typically taken once daily or as directed by your healthcare provider
    • Taking it after meals may help reduce the chance of stomach discomfort
    • Always follow your healthcare professional advice for best results

    Recommended Dosage Schedule for Adults

    Initial Dose

    • Adults are often started on 25 mg to 100 mg per day, either once daily or divided into two smaller doses taken morning and evening

    Maintenance Dose

    • Based on individual response and goals, the dose may be adjusted gradually
    • For ongoing support of fluid balance, the dosage may range between 25 mg to 100 mg per day

    How long can Aldactone 25mg be used?

    The duration for using Aldactone 25mg Tablet varies based on the individual’s medical needs, the reason for its use, and the response to the medicine. Some adults may use it for a short period to support temporary fluid balance, while others may require it as part of a long-term maintenance plan under ongoing supervision.

    Doctors typically recommend regular check-ups to assess:

    • Electrolyte levels (especially potassium and sodium)
    • Kidney function
    • The effectiveness of the dose over time

    What if I forgot to take ALDACTONE 25MG TABLET

    • If you forget to take a scheduled dose of Aldactone 25mg Tablet, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule
    • Do not take two doses at once to make up for the missed one, as this may increase the risk of side effects such as dizziness or changes in potassium levels

    Overdose

    If you or anyone else accidentally take too much of Aldactone 25mg Tablet, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include nausea, vomiting, drowsiness, confusion, skin rash or diarrhea.

    Side Effects Of ALDACTONE 25MG TABLET

    Common

    • increased urination
    • mild dizziness
    • breast discomfort
    • menstrual changes in some individuals

    When to consult a doctor?

    • low blood pressure
    • worsening of kidney function
    • low blood levels of magnesium, calcium, or chloride
    • high blood sugar levels

    Warning & Precautions

    Pregnancy

    Contraindicated

    Aldactone 25mg Tablet is generally not advised during pregnancy.

    Breastfeeding

    Use with Caution

    Spironolactone and its metabolites may pass into breast milk in small amounts. While data is limited, caution is advised when Aldactone 25mg Tablet is considered for breastfeeding mothers. Your doctor will help determine if it is suitable for use during this period or if alternative options should be explored.

    Driving and Using Machines

    Use with Caution

    Aldactone 25mg Tablet may cause drowsiness, dizziness, or light-headedness in some individuals, especially during the early days of use or after a dose adjustment. These effects can affect your ability to drive safely or operate machinery.  

    Alcohol

    Consult your doctor

    It is advisable to limit or avoid alcohol consumption while using Aldactone 25mg Tablet. Alcohol can intensify side effects such as dizziness, low blood pressure, or light-headedness, especially when standing up or during physical activity. This is because both Aldactone and alcohol may have a relaxing effect on blood vessels, which could make you feel faint or unsteady.

    Kidney

    Consult your doctor

    Aldactone 25mg Tablet is generally not advised for individuals with severely reduced kidney function or sudden worsening of kidney health, especially in cases where little to no urine is being produced. It should be used with caution in those with underlying kidney concerns such as advanced renal dysfunction.

    Liver

    Monitoring required

    Aldactone 25mg Tablet should be used carefully in individuals with serious liver conditions, and only under medical supervision.

    Allergy

    Contraindicated

    Do not take Aldactone 25mg Tablet if you are allergic to Spironolactone or any other ingredients of this medicine.

    Use In Pediatrics

    Consult your doctor

    Aldactone 25mg Tablet is generally not recommended for children with moderate to severe kidney conditions. It should be used cautiously in children with high blood pressure and only under the supervision of a pediatric specialist. Always consult your child’s doctor before administering this medicine.

    Use In Geriatrics

    Use with Caution

    Aldactone 25mg Tablet should be used carefully in elderly patients, particularly if there are existing kidney concerns.

    Who should not take [GBNKEYWORD

    Aldactone 25mg Tablet is usually not recommended if you:

    • have low sodium levels in your blood
    • have high potassium levels or conditions linked to potassium imbalance
    • have Addison’s disease (a condition where the adrenal glands produce insufficient hormones)

    Diet and Lifestyle Advice

    Things to Avoid while taking Aldactone 25mg Tablet

    1. High-Potassium Foods

    • Why: Aldactone may increase potassium levels in the blood
    • Avoid: Bananas, oranges, coconut water, tomatoes, spinach, avocados, and potassium salt substitutes

    2. Excessive Salt or Salt Substitutes

    • Why: Some salt substitutes contain potassium
    • Avoid: Potassium chloride-based seasonings unless approved by your doctor

    3. Alcohol Consumption

    • Why: Alcohol may enhance dizziness, drowsiness, or sudden drops in blood pressure
    • Avoid: Drinking alcohol while adjusting to the medicine, or before operating machinery

    4. Over-the-Counter NSAIDs

    • Why: Painkillers like ibuprofen or diclofenac may affect kidney function when used with Aldactone
    • Avoid: Self-medicating with pain relievers and always consult your doctor first.

    5. Dehydration or Excessive Fluid Loss

    • Why: Aldactone supports fluid balance, losing too much water (e.g., from diarrhea, vomiting, or sweating) can affect how it works
    • Avoid: Intense exercise or heat exposure without hydration guidance

    6. Combining with Certain Blood Pressure Medicines

    • Why: Some ACE inhibitors, ARBs, and diuretics can interact with Aldactone
    • Avoid: Starting or changing any heart or kidney-related medicines without informing your doctor

    Exercises that support better circulation while using diuretics

    • Ankle Pumps and Toe Flexes (For Desk or Bedside)
    • Walking (15–30 Minutes Daily)
    • Seated Leg Raises
    • Gentle Yoga or Stretching
    • Calf Raises

    Drug - Drug interaction

    Drug category

    Examples

    What to watch for

    Potassium supplements

    Potassium chloride

    May raise blood potassium levels too high

    ACE inhibitors

    Enalapril, Ramipril

    Increased risk of high potassium or low blood pressure

    Angiotensin receptor blockers

    Losartan, Telmisartan

    Similar interaction risk as with ACE inhibitors

    NSAIDs

    Ibuprofen, Diclofenac

    May reduce kidney function when taken together

    Diuretics (loop/thiazide)

    Furosemide, Hydrochlorothiazide

    Can lead to electrolyte imbalance

    Lithium

    -

    May increase lithium levels and side effects

    Digoxin

    -

    Spironolactone may affect digoxin concentration

    Drug - Food interaction

    • Avoid having foods rich in potassium while taking Aldactone 25mg Tablet
    • It is advisable to limit potassium-rich foods while using Aldactone 25mg Tablet, as this medicine may increase potassium levels in the blood
    • Examples of potassium-rich foods to limit bananas, oranges, tomatoes, potatoes, spinach, and coconut water

    Synopsis

    Drug :   Spironolactone
    Pharmacological Category :   Potassium-sparing diuretic
    Therapeutic Indication :   Fluid retention, Hypertension, Kidney disorders
    Dosage Forms :   Tablet

    More Information

    How does Aldactone 25mg Tablet compare to Furosemide or Amiloride?

    Feature

    Aldactone 25mg (Spironolactone)

    Furosemide

    Amiloride

    Type of Diuretic

    Potassium-sparing diuretic

    Loop diuretic

    Potassium-sparing diuretic

    Primary Action

    Reduces excess fluid by affecting aldosterone

    Rapid removal of excess fluid via loop of Henle

    Helps reduce fluid retention without potassium loss

    Effect on Potassium

    May increase potassium levels

    May lower potassium levels

    May increase potassium levels

    Speed of Action

    Slower onset, long-acting

    Fast-acting

    Moderate-acting

    Common Use Cases

    Hormone-sensitive conditions, mild to moderate fluid retention

    Severe fluid overload, high BP

    Mild fluid retention with potassium preservation

    Monitoring Required

    Potassium, kidney function

    Potassium, electrolytes

    Potassium, kidney function

    Use in Heart Conditions

    Yes, under guidance

    Yes, commonly used

    Yes, selectively used

    Use in Liver or Kidney Support

    With caution in liver/kidney issues

    Often used in edema with liver disease

    With caution in renal impairment

    Available as Combination

    Sometimes with hydrochlorothiazide

    Yes, often used in combinations

    Often combined with thiazides

    Doctor Supervision Required?

    Yes

    Yes

    Yes

     

    Did you know?

    Spironolactone has been studied for its role in supporting electrolyte balance. A PubMed analysis notes its potassium-conserving properties make it unique among diuretics.

    Natural ways to complement Aldactone 25mg

    • Following a sodium-moderated diet
    • Monitoring daily fluid intake
    • Incorporating foods rich in magnesium, unless otherwise advised

    FAQs About ALDACTONE 25MG TABLET

    Q: Can Aldactone 25mg Tablet be used in children?

    A: Aldactone 25mg Tablet is not recommended for use in children with moderate to severe kidney disease. It should be used with caution in children with hypertension. They should be managed under guidance of a pediatrician. Your doctor will decide the correct dose or select a suitable alternative therapy for your child.

    Q: Can Aldactone 25mg Tablet cause erectile dysfunction?

    A: Erectile dysfunction is an uncommon side effect of Aldactone 25mg Tablet. Consult your physician if you have trouble getting an erection or related symptoms.

    Q: Is Aldactone 25mg Tablet safe to use in pregnancy?

    A: Aldactone 25mg Tablet is not recommended for use in pregnant women. So before taking Aldactone 25mg Tablet, inform your doctor if you are pregnant, think you might be pregnant, or planning to get pregnant.

    Q: Can I stop taking Aldactone 25mg Tablet?

    A: Do not stop taking Aldactone 25mg Tablet unless your doctor advises you to stop. Your original symptoms may return if you stop taking it suddenly. Ask for your doctor’s advice if you wish to discontinue taking Aldactone 25mg Tablet.

    Q: Can Aldactone 25mg Tablet be crushed?

    A: Aldactone 25mg Tablet should be generally swallowed whole with a glass of water, but to make it easier for children to take, the medicine may first be ground or crushed and then mixed in a glass of water by stirring. If you have any further doubts regarding use of Aldactone 25mg Tablet, contact your doctor.

    Q: What if I forget to take a dose of Aldactone 25mg Tablet?

    A: If you forget to take a dose of Aldactone 25mg Tablet, take it as soon as you remember, and then continue your management as usual. Do not take the medicine twice to make up for the forgotten dose. If you have any further doubts regarding use of Aldactone 25mg Tablet contact your doctor.

    Q: Can I take Aldactone 25mg before meals?

    A: Aldactone 25mg Tablet can be taken either with or after meals. Taking it after food may help reduce the chance of stomach upset. It is best to take it at the same time each day to maintain consistent levels in your body.

    Q: Should I Be Concerned About Dizziness or Fatigue?

    A: Mild dizziness or fatigue can occur when starting Aldactone 25mg Tablet, especially during the first few days or after a dose change. This may happen due to the medicine’s effect on blood pressure or fluid balance in the body.

    Q: Is hair loss or hair growth linked to Aldactone use?

    A: Aldactone 25mg Tablet contains spironolactone, which is sometimes prescribed under medical guidance for hormone-related concerns. In certain cases, spironolactone has been observed to influence hair growth patterns, particularly in individuals with hormone-related hair issues.

    Q: Is Aldactone used for hormonal bloating?

    A: Aldactone 25mg Tablet helps to manage fluid balance in certain hormone-related conditions under medical guidance. In some cases, healthcare providers may consider it when addressing concerns like cyclical bloating associated with hormonal fluctuations such as during specific phases of the menstrual cycle.

    Q: Does Aldactone cause frequent urination?

    A: Yes, frequent urination is a commonly observed effect when starting Aldactone 25mg Tablet. This happens because the medicine contains spironolactone, which supports the body in managing excess fluid through its diuretic action.

    Q: Can Aldactone cause irregular periods or breast tenderness?

    A: Yes, changes in menstrual cycle patterns and breast tenderness have been reported by some individuals taking Aldactone 25mg Tablet, especially when used over a longer duration or under hormone-related conditions.

    References

    1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Hypertension. Pharmacotherapy Handbook. Ninth edition. Page- 87.

    2. Andreas P Kalogeropoulos,, Jincy Thankachen, Javed Butler, James C Fang. Diuretic and renal effects of spironolactone and heart failure hospitalizations: a TOPCAT Americas analysis. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed.gov. September 2020. [Accessed on 10th June 2025] 

    3. Chen C, Zhu XY, Li D, Lin Q, Zhou K. Clinical efficacy and safety of spironolactone in patients with resistant hypertension: A systematic review and meta-analysis. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed.gov. August 2020. [Accessed on 10th June 2025] 

    4. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed on 10th June 2025] 

    5. Pfizer Labs. Spironolactone. [Revised in February 2021] [Accessed on 10th June 2025] 

    6. Fluid retention (oedema). Better Health Channel. [Accessed on 10th June 2025] 

    Author Details

    Written By Dr. Janet.C - Pharm.D
    Reviewed For Accuracy By Dr. Venkatesh Poludasu - MBBS
    Last updated on 11 Jun 2025 | 03:14 PM(IST)
    Lab updated