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Introduction About ZYFIX LB TABLET
ZYFIX LB TABLET is a combination of Cefixime and Lactobacillus, which belong to the group of medicines called Antibiotics and Probiotics, respectively. ZYFIX LB TABLET is used in the management of bacterial infections like tonsillitis, pharyngitis, pneumonia, bronchitis, and other respiratory tract infections, skin and soft tissue infections, and urinary tract infections. Lactobacillus is used to manage diarrhea associated with the intake of cefixime.
Before taking ZYFIX LB TABLET, inform your doctor if you have swelling or inflammation of the large intestine (colon), kidney impairment, intestinal damage, had bowel surgery recently, and if you are allergic to other cephalosporin antibiotics, including penicillin.
ZYFIX LB TABLET should be used with caution in pregnant women, and it is not recommended for use in breastfeeding women. ZYFIX LB TABLET is not recommended for use in children under 10 years of age, and it should be used with caution in elderly patients (aged 65 years and above).
The common side effects of taking ZYFIX LB TABLET are nausea, vomiting, indigestion, and headache. Consult with your doctor if any of the side effects worsen.
Uses Of ZYFIX LB TABLET
Manage:
- Tonsillitis
- Pharyngitis
- Pneumonia
- Bronchitis & other respiratory tract infections
- Skin & soft tissue infections
- Urinary tract infections
How ZYFIX LB TABLET Works
ZYFIX LB TABLET is a combination of Cefixime and Lactobacillus. Cefixime works against both gram-positive and gram-negative organisms. It acts by inhibiting bacterial cell wall synthesis, which is essential for the survival of bacteria in the human body. It inhibits transpeptidase (a bacterial enzyme) and manages the cross-linking of the bacterial cell wall, resulting in the killing of bacteria. Lactobacillus acts as a probiotic, which is used along with antibiotics to restore the body`s natural microbial flora within the digestive tract. It inhibits or decreases the growth of harmful microorganisms in the gut by producing lactic acid. This collective action is useful in managing infections caused by bacteria.
How to use ZYFIX LB TABLET
Take ZYFIX LB TABLET as advised by your physician. It can be taken with or without food.
For Tablet: Swallow ZYFIX LB TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned in the label. Consume the medicine immediately after reconstitution.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and severity of the infection.
Side Effects Of ZYFIX LB TABLET
Common
- Nausea, vomiting
- Indigestion
- Headache
Rare
Stop taking ZYFIX LB TABLET and contact your doctor immediately if you experience any of the following side effects:
- Severe allergic reactions (signs include skin rash, severe itching of the skin with raised lumps, blisters in the skin, swelling of the face, lips, tongue, and/or throat with difficulty in breathing or swallowing)
- Severe skin problems such as toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) (signs include blistering, peeling, or bleeding on any part of the skin, including the lips, eyes, mouth, nose, genitals, hands, or feet). Also, flu-like symptoms such as fever, chills, or aching muscles) and acute generalized exanthematous pustulosis (AGEP) (signs include red, scaly, widespread rash with bumps under the skin, including your skin folds, chest, abdomen (including stomach), back, and arms), and blisters accompanied by fever)
- Drug rash with eosinophilia and systemic symptoms (DRESS) (signs include flu-like symptoms and a widespread rash with a high body temperature and enlarged lymph nodes)
- Severe watery diarrhea that will not stop, and you are feeling weak and have a fever; this may be something called ‘pseudomembranous colitis’
- Get infections more easily than usual
- Bruise or bleed more easily than normal
- Nose bleeds, bleeding gums, chills, tiredness, pale skin (often with a yellow tinge), shortness of breath
- Blood in urine
- Fits (convulsions)
- Brain condition with symptoms including fits (convulsions), feeling confused, feeling less alert or aware of things than usual, unusual muscle movements, or stiffness
How To Manage Side Effects

Diarrhea
Drink lots of fluids, such as water, to keep yourself hydrated. Avoid eating high-fat or spicy foods. Avoid taking any medicine on your own for managing diarrhea. Consult your doctor if the symptom does not improve.

Nausea And Vomiting
Take this medicine with or immediately after food. Stick to simple meals. Avoid eating oily, fried, and spicy foods. Do not perform any strenuous activities immediately after eating. Consult your doctor if the symptom does not improve.
Warning & Precautions

Pregnancy
Use with CautionZYFIX LB TABLET should be used with caution in pregnant women. Consult your doctor before taking ZYFIX LB TABLET.

Breastfeeding
ContraindicatedZYFIX LB TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking ZYFIX LB TABLET.

Driving and Using Machines
ContraindicatedDo not drive or operate any machines if you experience fits, confusion, feeling less alert or aware of things than usual, unusual muscle movements, or stiffness after taking ZYFIX LB TABLET.

Alcohol
ContraindicatedAvoid consumption of alcohol while taking ZYFIX LB TABLET because it might make you dizzier.

Kidney
Use with CautionZYFIX LB TABLET should be used with caution in patients with impaired kidney function. Consult your doctor before taking ZYFIX LB TABLET.

Allergy
ContraindicatedDo not take ZYFIX LB TABLET if you are allergic to cefixime or any other cephalosporin antibiotics, including penicillin.

Use In Pediatrics
Use with CautionZYFIX LB TABLET should be used with caution in children over 10 years of age or weighing more than 50 kg. Consult your child’s for advice.

Use In Geriatrics
Use with CautionZYFIX LB TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking ZYFIX LB TABLET.
Others
ZYFIX LB TABLET is not recommended for use if you:
- Have colitis (swelling or inflammation of the large intestine)
- Have weakened immune system
- Have intestinal damage
- Had bowel surgery recently
Interactions
A. Drug-drug interactions:
Before taking ZYFIX LB TABLET, inform your doctor if you are taking any of the following medicines:
- Salicylates such as aspirin (used to manage fever and pain)
- Probenecid (used to manage gout)
- Warfarin (used to manage or manage blood clots)
- Insulin (used to manage diabetes mellitus)
Overdosage:
If you or anyone else accidentally takes too much of ZYFIX LB TABLET, consult your doctor immediately or visit the nearby hospital. Overdose symptoms of ZYFIX LB TABLET are blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting.
Synopsis
Drug | : | Cefixime, Lactobacillus |
Pharmacological Category | : | Cephalosporin antibiotics, Probiotics |
Therapeutic Indication | : | Various bacterial infections |
Dosage Forms | : | Tablet, Capsule, Dispersible tablet, Dry suspension, Dry syrup, Oral suspension, Powder, Rediuse, Syrup |
More Information
Storage
- Keep ZYFIX LB TABLET out of reach of children
- Store ZYFIX LB TABLET at room temperature
FAQs About ZYFIX LB TABLET
Q: What is ZYFIX LB TABLET and why is it prescribed?
A: ZYFIX LB TABLET is a combination of Cefixime and Lactobacillus, which belong to the group of medicines called Antibiotics and Probiotics, respectively. ZYFIX LB TABLET is used in the management of bacterial infections like tonsillitis, pharyngitis, pneumonia, bronchitis, and other respiratory tract infections, skin and soft tissue infections, and urinary tract infections. Lactobacillus is used to manage diarrhea associated with the intake of cefixime.
Q: What are the side effects of ZYFIX LB TABLET?
A: The most common side effects of taking ZYFIX LB TABLET are nausea, vomiting, indigestion, and headache. Consult with your doctor if any of the side effects worsen over time.
Q: Is ZYFIX LB TABLET safe to use in patients with kidney problems?
A: ZYFIX LB TABLET should be used with caution in patients with impaired kidney function. Your doctor may monitor your kidney function during and after management with this medicine to manage the risk of any unusual effects. Consult your doctor before taking it.
Q: What happens if I accidentally take an extra dose of ZYFIX LB TABLET?
A: If you or anyone else accidentally takes too much of ZYFIX LB TABLET, consult your doctor immediately or visit the nearby hospital. Overdose symptoms of ZYFIX LB TABLET are blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting.
Q: Can ZYFIX LB TABLET be used in pregnant and breast-feeding women?
A: ZYFIX LB TABLET should be used with caution in pregnant women, and it is not recommended for use in breastfeeding women. Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding your baby.
Q: How does ZYFIX LB TABLET work?
A: ZYFIX LB TABLET contains Cefixime that works against both gram-positive and gram-negative organisms. It acts by inhibiting bacterial cell wall synthesis, which is essential for the survival of bacteria in the human body. It inhibits transpeptidase (a bacterial enzyme) and manages the cross-linking of the bacterial cell wall, resulting in the killing of bacteria. Lactobacillus acts as a probiotic, which is used along with antibiotics to restore the body`s natural microbial flora within the digestive tract. It inhibits or decreases the growth of harmful microorganisms in the gut by producing lactic acid. This collective action is useful in managing infections caused by bacteria.
Q: Is ZYFIX LB TABLET safe for kids?
A: ZYFIX LB TABLET should be used with caution in children over 10 years of age or weighing more than 50 kg. Consult your child’s for advice.
Q: What should I avoid while taking ZYFIX LB TABLET?
A: Avoid consumption of alcohol while taking ZYFIX LB TABLET because it might make you dizzier.
Q: Who should not take ZYFIX LB TABLET?
A: ZYFIX LB TABLET is not recommended for use if you have colitis (swelling or inflammation of the large intestine), a weakened immune system, intestinal damage, have had bowel surgery recently, or if you are allergic to cefixime or any other cephalosporin antibiotics, including penicillin.
Q: What precautions must be taken while using ZYFIX LB TABLET?
A: ZYFIX LB TABLET should be used with caution in patients with impaired kidney function. Consult your doctor before taking ZYFIX LB TABLET.
References
1. KD. Tripathi. Antimicrobial Drugs: General Considerations. Essentials of Medical Pharmacology. Seventh Edition. 2017. Page – 687 & 703.
2. Song HJ, Kim JY, Jung SA, Kim SE, Park HS, Jeong Y, Hong SP, Cheon JH, Kim WH, Kim HJ, Ye BD, Yang SK, Kim SW, Shin SJ, Kim HS, Sung JK, Kim EY. Effect of probiotic Lactobacillus for the prevention of antibiotic-associated diarrhoea: a prospective, randomized, double-blind, multicenter study. NIH National Library of Medicine, National Center for Biotechnology Information. December 2010 [Accessed on 23rd July 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995234/
3. University of Southern California. Cefixime Clinical Trial. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in June 2022] [Accessed on 23rd July 2024] https://clinicaltrials.gov/ct2/show/NCT04958122
4. Famar Lyon. Electronic Medicines Compendium (EMC). [Revised in April 2021] [Accessed on 23rd July 2024] https://www.medicines.org.uk/emc/files/pil.15047.pdf
5. Medicine India. Cefixime and Lactobacillus. [Accessed on 23rd July 2024] https://www.medicineindia.org/pharmacology-for-generic/357/cefixime-lactobacillus
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Kidney Function Test (KFT)
- Peripheral Smear Examination By Pathologist
- Serum Electrolytes/ Electrolytes Profile
- Culture & Sensitivity, Blood
- Healthy Midlife Checkup
- Senior Citizen Checkup - Female
- Senior Citizen Checkup - Male
- Women Health Checkup - Essential
- Full Body Checkup – Gold