ZILARTA CT 40/6.25mg Tablet 10's

Hypertension Rx required

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(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Micro Labs Ltd * Country of Origin: NA * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

ZILARTA CT 40/6.25MG is a fixed-dose combination of Azilsartan and Chlorthalidone which belongs to the group of medicines called Antihypertensive agents. It is used in adults to treat hypertension. Hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high, and as a result it may lead to severe damage to the blood vessels supplying several organs, like heart, kidney, or brain.

Azilsartan is an angiotensin II receptor blocker. It acts by relaxing the blood vessels supplying the vital organs. Chlorthalidone is a thiazide-diuretic. It acts by increasing the removal of water and certain electrolytes (sodium and chloride) from the body in the form of urine which eventually reduces blood volume. Collectively, they improve blood flow through the blood vessels and reduces the elevated blood pressure.

While undergoing therapy with ZILARTA CT 40/6.25MG your doctor will regularly monitor your blood pressure, kidney function, blood sugar, cholesterol or uric acid levels and electrolyte profile (sodium, potassium, and magnesium levels) to avoid the risk of unwanted side effects.

Before taking ZILARTA CT 40/6.25MG inform your doctor if you have any heart, kidney, or liver problems. You must also inform your doctor if you have diabetes related kidney problems, gout, or are severely dehydrated (due to vomiting or diarrhea).

ZILARTA CT 40/6.25MG is strictly not recommended for use in pregnant or breastfeeding women. Women taking ZILARTA CT 40/6.25MG must inform their doctor immediately if they become pregnant while undergoing therapy with ZILARTA CT 40/6.25MG.

ZILARTA CT 40/6.25MG may make you feel dizzy or faint. Therefore, be cautious while you drive or operate any tools that requires proper attention. Other common side effects of ZILARTA CT 40/6.25MG are low blood potassium levels, tiredness, or muscle spasms. Consult your doctor if any of these side effect worsens.

USES OF ZILARTA CT 40/6.25MG

  • Treats hypertension in adults

HOW ZILARTA CT 40/6.25MG WORKS

ZILARTA CT 40/6.25MG effectively controls blood pressure. It contains azilsartan and chlorthalidone. Azilsartan blocks the actions of a peptide hormone called angiotensin-II that increases blood pressure. This makes the blood vessels to relax and improves blood flow within them. Chlorthalidone increases the excretion of water and electrolytes (sodium and chloride) from the body in the form of urine. This reduces blood volume which makes the blood to be pumped easier by the heart with less pressure. Collectively they reduces blood pressure.

DIRECTIONS FOR USE

Take ZILARTA CT 40/6.25MG as directed by the physician. Swallow ZILARTA CT 40/6.25MG with a glass of water. Do not crush or chew the medicine. ZILARTA CT 40/6.25MG can be taken with or without meals.

Your doctor will decide the correct dose and for how long ZILARTA CT 40/6.25MG must be taken depending upon your age, body weight and disease condition. Do not stop taking ZILARTA CT 40/6.25MG without consulting your doctor.

SIDE EFFECTS OF ZILARTA CT 40/6.25MG

COMMON

  • feeling dizzy or faint with or without changing position
  • diarrhea, nausea, loss of appetite, stomach upset
  • feeling tired
  • muscle spasms
  • swelling of the hands, ankles, or feet
  • skin rash, itching
  • impotence in men
  • worsening of blood cholesterol
  • hypokalaemia (decrease in serum potassium levels)
  • increase in creatinine and uric acid levels

UNCOMMON

  • fainting
  • sense of tingling and numbness
  • vomiting
  • gout (pain and swelling in the joints)
  • anaemia (low RBC count)
  • worsening of diabetes
  • migraine (severe headache on one side)

RARE

  • abnormal heartbeat
  • yellowing of the skin or eyes caused by liver problems
  • increased photosensitivity (sensitivity to sunlight)
  • problems in breathing due to fluid build-up in the lungs
  • stomach pain, constipation

Stop taking ZILARTA CT 40/6.25MG and contact your doctor immediately if you experience any of the following side effects:

  • signs of allergic reactions (such as swelling of the face, lips, tongue, and/or throat which can lead to difficulty in breathing or swallowing)
  • decrease in vision

HOW TO MANAGE SIDE EFFECTS

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Nausea and Vomiting:

Take ZILARTA CT 40/6.25MG with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.

WARNING & PRECAUTIONS

PREGNANCY

ZILARTA CT 40/6.25MG is strictly not recommended for use in pregnant women as it may cause serious harm to the unborn baby. Therefore, consult your doctor before taking it. Women taking ZILARTA CT 40/6.25MG must inform their doctor immediately if they become pregnant while undergoing therapy with ZILARTA CT 40/6.25MG.

BREASTFEEDING

ZILARTA CT 40/6.25MG is not recommended for use in breast feeding women. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any tools or machines if you feel dizzy after taking ZILARTA CT 40/6.25MG.

ALCOHOL

Avoid consumption of alcohol while undergoing therapy ZILARTA CT 40/6.25MG as it may make you feel dizzy or drowsy.

KIDNEY

ZILARTA CT 40/6.25MG is not recommended for use in patients with severe kidney diseases or problems in passing urine. It should be used with caution in patients with other kidney problems (such as dialysis or any recent kidney transplant). Therefore, consult your doctor before taking it.

LIVER

ZILARTA CT 40/6.25MG is not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it.

ALLERGY

Do not take ZILARTA CT 40/6.25MG if you are allergic to Azilsartan or Chlorthalidone.

HEART DISEASE

ZILARTA CT 40/6.25MG should be used with caution in patients with heart problems (such as heart attack or failure, low blood pressure, narrowing or heart valves or increase in thickness of heart muscles). Therefore, consult your doctor before taking it.

OTHERS

ZILARTA CT 40/6.25MG is not recommended for use if you:

  • have low levels of sodium in the blood that cannot be corrected despite treatment
  • have high blood calcium levels
  • have gout or high levels of uric acid in the blood
  • have diabetes

Before taking ZILARTA CT 40/6.25MG, inform your doctor if you:

  • have ever had a stroke
  • have muscle pains, cramps, or weakness
  • are severely dehydrated or have conditions such as nausea, vomiting or diarrhoea that may make you dehydrate very easily
  • have dry mouth, thirst, or feeling tired
  • have primary hyperaldosteronism (problems in adrenal gland)

Use in pediatrics:

ZILARTA CT 40/6.25MG should not be used in children and adolescents (below 18 years) due to lack of safety data. Therefore, consult your doctor before taking it.

Use in geriatrics:

ZILARTA CT 40/6.25MG should be used with caution in elderly patients. Therefore, consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug Interaction:

Before taking ZILARTA CT 40/6.25MG, inform your doctor if you are taking any of the following medicines such as:

  • other medicines that can control blood pressure (such as captopril, enalapril, lisinopril, ramipril, valsartan, telmisartan, irbesartan or aliskiren)
  • lithium (a medicine used to treat mental illnesses)
  • non-steroidal anti-inflammatory drugs (used for pain relief) such as ibuprofen, diclofenac, celecoxib, or aspirin
  • medicines used to increase potassium levels in the blood such as potassium supplements, or potassium-sparing medicines (such as spironolactone, aldosterone)
  • medicines that can reduce blood potassium levels such as amphotericin, carbenoxolone, prednisone, or ACTH
  • heparin (a medicine used for blood thinning)
  • medicines used to treat diabetes (such as metformin, glimepiride)
  • medicines used to treat gout (Ex. allopurinol, probenecid)
  • medicines used to treat asthma (Ex. salbutamol, budesonide, formoterol)
  • digitalis (a medicine used to correct abnormal heart rhythm)
  • anticholinergics (used to reduce muscle spasms and to increase heart functions) such as atropine
  • amantadine (a medicine used to treat viral infections or Parkinson´s disease)
  • cholestyramine (a medicine used to reduce blood cholesterol levels)
  • ciclosporin (a medicine used to suppress immune functions or to prevent graft rejection)
  • medicines used to treat cancer (Ex. cyclophosphamide or methotrexate)
  • Vitamin D and calcium supplements

Overdosage:

If you or anyone else accidentally took more ZILARTA CT 40/6.25MG, consult your doctor immediately. Symptoms of overdosage might include feeling dizzy or faint.

SYNOPSIS

Drug :  

Azilsartan, Chlorthalidone

Pharmacological Category :  

Angiotensin Receptor Blockers, Thiazide Diuretics

Therapeutic Indication :  

Hypertension

Dosage Forms :  

Tablet

MORE INFORMATION

  • Keep ZILARTA CT 40/6.25MG out of reach to children
  • Store ZILARTA CT 40/6.25MG at room temperature

FAQs ABOUT ZILARTA CT 40/6.25MG

What are the uses of ZILARTA CT 40/6.25MG?

ZILARTA CT 40/6.25MG is used in adults to treat hypertension. It effectively controls blood pressure, where azilsartan acts by relaxing the blood vessels and chlorthalidone acts by increasing the excretion of sodium and water from the body in the form of urine. Collectively, they relax blood vessels, improves blood flow and reduces blood pressure.

What type of a drug is ZILARTA CT 40/6.25MG?

ZILARTA CT 40/6.25MG is an antihypertensive medicine used to reduce elevated blood pressure. It contains a combination of two medicines called azilsartan and chlorthalidone. Azilsartan is an angiotensin II receptor blocker and chlorthalidone is a thiazide-diuretic. They both acts together in reducing blood pressure.

What are the side effects of ZILARTA CT 40/6.25MG?

ZILARTA CT 40/6.25MG may make you feel dizzy or faint. Therefore, be cautious while you drive or operate any tools that requires proper attention. Other common side effects of ZILARTA CT 40/6.25MG are low blood potassium levels, tiredness, or muscle spasms. Consult your doctor if any of these side effect worsens.

Can the use of ZILARTA CT 40/6.25MG cause kidney problems?

Yes. The use of ZILARTA CT 40/6.25MG may affect your kidney functions. It is strictly not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems (such as dialysis or any recent kidney transplant). Therefore, consult your doctor before taking ZILARTA CT 40/6.25MG as a precaution.

Can ZILARTA CT 40/6.25MG reduce blood pressure?

Yes. ZILARTA CT 40/6.25MG effectively controls blood pressure in patients with hypertension.

What happens when I stop taking ZILARTA CT 40/6.25MG?

Do not stop taking ZILARTA CT 40/6.25MG without consulting your doctor as your blood pressure may raise once again. Make sure to take ZILARTA CT 40/6.25MG for the stipulated duration recommended by your doctor to achieve maximum results.

What is the best time to take ZILARTA CT 40/6.25MG?

ZILARTA CT 40/6.25MG can be taken with or without meals. Your doctor will decide the best time for you to take ZILARTA CT 40/6.25MG based on your age, body weight and disease condition.

How long will it take for ZILARTA CT 40/6.25MG to show the results?

You might be able to notice a reduction in your blood pressure within 1-2 weeks of starting therapy with ZILARTA CT 40/6.25MG. However, it may take around 4 weeks for you to notice the maximum benefits. Therefore, continue to take ZILARTA CT 40/6.25MG as advised by your doctor.

What to do if I forgot to take a dose of ZILARTA CT 40/6.25MG?

If you have missed a dose of ZILARTA CT 40/6.25MG, take it as soon as you remember. However, if it is time for the next dose of ZILARTA CT 40/6.25MG, skip the missed dose and take the next one regularly. Do not take a double dose of ZILARTA CT 40/6.25MG to compensate the missed ones.

REFERENCES

1. K.D. Tripathi. Diuretics. Antihypertensives. Essential of Medical Pharmacology. 7th Edition. 2013. Page: 583-586 and 561.

2. David J. Collier MD, PhD, Attila Juhasz MD, PhD, Enrico Agabiti-Rosei MD, PhD, Eric Lloyd MS, Michie Hisada MD, MPH, ScD, Lin Zhao PhD, Stuart Kupfer MD, Mark J. Caulfield MD. Efficacy and safety of azilsartan medoxomil/chlortalidone fixed-dose combination in hypertensive patients uncontrolled on azilsartan medoxomil alone: A randomized trial. Wiley Online Library. October 2018. [Accessed on 23rd June 2022] https://onlinelibrary.wiley.com/doi/10.1111/jch.13376

3. Ipca Laboratories. Optimising TRIUMPH with 6·25 mg chlorthalidone. The Lancet.com. February 2020. [Accessed on 23rd June 2022] https://www.thelancet.com/pdfs/journals/langlo/PIIS2214-109X(19)30535-2.pdf

4. Takeda Ireland Limited. Health Products Regulatory Authority (HPRA). [Revised in December 2021] [Accessed on 23rd June 2022] https://www.hpra.ie/img/uploaded/swedocuments/cf80a3a8-cab0-4606-85da-ef6eb00fe5ee.pdf

5. Takeda Pharmaceuticals America, Inc. U.S. Food & Drug Administration. [Revised in December 2011] [Accessed on 23rd June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/202331lbl.pdf

USEFUL DIAGNOSTIC TESTS

  • Kidney Function Tests

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    AZILSARTAN MEDOXOMIL 40 mg+CHLORTHALIDONE 6.25 mg
    Hsn Code
    30049079
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

ZILARTA CT 40/6.25mg Tablet 10's

ZILARTA CT 40/6.25mg Tablet 10's Mkt: Micro Labs Ltd

M.R.P.: Rs.129.00
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