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Introduction About TRITELSAR HS 80MG TABLET
TRITELSAR HS 80MG TABLET is a combination of Chlorthalidone, Amlodipine and Telmisartan which belongs to the group of medicines called Antihypertensives. TRITELSAR HS 80MG TABLET is used to manage essential hypertension in adults. Essential hypertension (primary hypertension) occurs when you have abnormally high blood pressure that's not the result of a medical condition. It is characterized by symptoms such as blurred vision, severe headache, chest pain, dizziness, light-headedness and nose bleeds.
TRITELSAR HS 80MG TABLET is not recommended for use in patients having severe liver, kidney and heart problems. Avoid eating or drinking grapefruit juice while taking TRITELSAR HS 80MG TABLET as it may potentiate the risk of side effects. Prior to management with TRITELSAR HS 80MG TABLET or during the course of management, your doctor may want you to take several tests to understand your health condition.
TRITELSAR HS 80MG TABLET is not recommended for use in pregnant and breastfeeding woman. It is not recommended for use in children and adolescents (aged less than 18 years) and it should be used with caution in elderly patients (above 65 years of age).
The common side effects of taking TRITELSAR HS 80MG TABLET are low blood pressure, dizziness, loss of appetite, stomach upset and skin rashes. Consult your doctor immediately if any of the side effect worsens.
Uses Of TRITELSAR HS 80MG TABLET
- Manage essential hypertension
How TRITELSAR HS 80MG TABLET Works
TRITELSAR HS 80MG TABLET helps to reduce high blood pressure, where amlodipine works by relaxing the blood vessels and improving the flow of blood to the heart muscles and chlorthalidone works by promoting the excretion of excess fluid and certain electrolytes (such as sodium and chloride) from the body by increasing the amount of urine produced by the kidneys. Telmisartan works by relaxing the blood vessels by managing the binding of certain substance called angiotensin-II (substance produced in the body which causes narrowing of blood vessels). All these actions together effectively control high blood pressure.
How to use TRITELSAR HS 80MG TABLET
Take TRITELSAR HS 80MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of TRITELSAR HS 80MG TABLET for you depending upon your age, body weight and disease condition.
Side Effects Of TRITELSAR HS 80MG TABLET
Common
- oedema (swelling due to fluid retention)
- low blood levels of potassium which can cause muscle weakness, muscle twitching
- low blood pressure
- low levels of sodium which can cause tiredness, confusion, muscle twitching
- fits or coma
- high blood sugar levels which can cause tiredness, weakness or feeling thirsty
- nettle like skin rash
- dizziness
- loss of appetite, stomach upset
- impotence in men
Uncommon
- urinary tract infections
- upper respiratory tract infections (signs include sore throat, inflamed sinuses, common cold)
- decreased red blood cells (anemia)
- difficulty falling asleep
- fainting
- head spinning sensation (vertigo)
- slow heart rate
- dizziness on standing up (orthostatic hypotension)
- shortness of breath, cough
- abdominal pain, diarrhoea, vomiting and bloating
- itching and increased sweating
- back pain, muscle cramps and muscle pain
- chest pain, feeling of weakness
- ringing in the ears
- sneezing/running nose caused by inflammation of the lining of the nose
- dry mouth
- hair loss, red patches on skin, skin discoloration
- difficulty in passing urine, increased urge to urinate at night, increased frequency of passing urine
- discomfort or enlargement of the breasts in men
- weight gain or decrease
- gout (pain and swelling in the joint)
Rare
- signs of increased calcium levels (agitation, sore eyes, abdominal pain)
- swelling of face or gums
- low blood sugar level in diabetic patients, worsening of diabetes
- signs of jaundice (yellowing of skin or eyes)
- increased skin sensitivity to sunlight
- impaired vision
- fast heartbeat
- altered taste sensation
- eczema, hives (urticaria)
- severe skin rash caused by drug, joint, tendon and extremities pain
- flulike illness such as fever, chills and throat pain
- signs of kidney problems (such as loss of appetite, decreased urinary output, fatigue)
- confusion and anxiety
- palpitations
- tingling and prickling sensation in arms, legs or feet
Stop taking TRITELSAR HS 80MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of sepsis (rapid swelling of the skin and mucosa)
- sudden wheezing, chest pain, shortness of breath or difficulty in breathing
- swelling of eyelids, face or lips
- swelling of the tongue and throat which causes great difficulty breathing
- signs of stevens johnson syndrome, toxic epidermal necrolysis or other allergic reactions (severe skin reactions causing intense rash, hives, reddening of the skin over the whole body, severe itching, blistering, peeling and swelling of the skin, inflammation of mucous membranes)
- heart attack, abnormal heartbeat
- signs of inflamed pancreas (severe abdominal and back pain)
- severe muscles weakness
How To Manage Side Effects
Diarrhea
Drink lot of fluids such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Do not take any medicine on your own to manage diarrhea without consulting your doctor.
Dizziness Or Drowsiness
Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Consult your doctor if the symptom gets worse.
Dry Mouth
Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.
Loss Of Appetite
Eat when you feel hungry. Eat smaller meals frequently than usual. Snack only when you're hungry. Eat a nutritious snack which is rich in calories and protein, such as dried fruit and nuts. Consult your doctor if the symptom does not improve.
Skin rash Or Itching
Try to avoid hot showers because it may cause skin irritation. Avoid frequent contact and rubbing over the affected area. Use sunscreen and protective clothing when going outdoors. Consult your doctor if the symptom does not improve.
Stomach Pain
Try to rest and relax. Eat and drink slowly or try to have smaller meals more frequently. Keep a heat pad on your stomach. If the symptom does not improve, consult your doctor.
Warning & Precautions
Pregnancy
ContraindicatedTRITELSAR HS 80MG TABLET is not generally recommended for pregnant women as it may cause serious harm to the baby. Consult your doctor before taking TRITELSAR HS 80MG TABLET.
Breastfeeding
ContraindicatedTRITELSAR HS 80MG TABLET is not recommended for use in breastfeeding women, as it may pass through breast milk. Your doctor may choose another management especially if you want to breast-feed when your baby is new-born or born prematurely. Consult your doctor before taking TRITELSAR HS 80MG TABLET.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizziness, tiredness, headache or feel sick after taking TRITELSAR HS 80MG TABLET.
Alcohol
Consult your doctorAvoid consumption of alcohol with TRITELSAR HS 80MG TABLET as it may increase the risk of low blood pressure.
Kidney
Consult your doctorTRITELSAR HS 80MG TABLET is not recommended for use in patients with kidney stones and it should be taken with caution in patients having kidney artery stenosis (narrowing of blood vessels to one or both the kidneys) and kidney transplant. Consult your doctor before taking TRITELSAR HS 80MG TABLET.
Liver
Consult your doctorTRITELSAR HS 80MG TABLET is not recommended for use in patients with severe liver problems such as cholestasis or biliary obstruction (flow of bile from liver stops or slows). It should be used with caution in patients having liver disease. Consult your doctor before taking TRITELSAR HS 80MG TABLET.
Allergy
ContraindicatedTRITELSAR HS 80MG TABLET is not recommended for use if you are allergic to Amlodipine, Chlorthalidone and Telmisartan.
Heart Disease
Consult your doctorTRITELSAR HS 80MG TABLET is not recommended for use in patients with cardiogenic shock (when the heart is unable to supply enough blood to the vital organs of the body), aortic stenosis (narrowed or blocked aortic valve), heart failure after heart attack. It should be used with caution in patients having heart trouble or low blood pressure (due to dehydration problems, low-salt intake, diarrhoea, or vomiting). Before taking TRITELSAR HS 80MG TABLET consult with your doctor.
Use In Pediatrics
ContraindicatedTRITELSAR HS 80MG TABLET is not recommended for use in children and adolescents (under 18 years of age). Consult child’s doctor for advice.
Use In Geriatrics
Use with CautionTRITELSAR HS 80MG TABLET should be used with caution in elderly patients (above 65 years of age). Consult your doctor before taking TRITELSAR HS 80MG TABLET
Others
TRITELSAR HS 80MG TABLET is not recommended for use if you:
- are not passing urine at all
- have low levels of potassium, sodium and calcium in the blood
- have gout
- have addison’s disease
Before taking TRITELSAR HS 80MG TABLET, inform your doctor if you have:
- raised aldosterone levels
- diabetes (high blood sugar)
Interactions
A. Drug-Drug interactions:
Before taking TRITELSAR HS 80MG TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used to lower the blood pressure (Ex. enalapril, lisinopril, ramipril, verapamil, diltiazem, aliskiren, bosentan, methyldopa and guanethidine)
- medicines that may increase blood potassium levels (Ex. amiloride, spironolactone)
- medicines used to manage pain and inflammation (Ex. aspirin, ibuprofen)
- heparin (used to manage blood clots)
- cyclosporin, tacrolimus, sirolimus, temsirolimus, and everolimus (used to manage organ rejection after transplant)
- medicines used to manage bacterial infections (Ex. clarithromycin, erythromycin, amphotericin, telithromycin, rifampicin, rifabutin and trimethoprim)
- furosemide, hydrochlorothiazide (used to manage oedema or high blood pressure)
- medicines used to suppress inflammation (Ex. prednisolone, betamethasone, dexamethasone and hydrocortisone)
- medicines used to manage depression (Ex. lithium, citalopram, fluoxetine, paroxetine, nefazodone and St. John’s wort (herbal medicine))
- itraconazole, ketoconazole (used to manage fungal infections)
- antiviral medicines used to manage HIV infections (Ex. ritonavir, indinavir, nelfinavir, nevirapine)
- simvastatin, colestyramine (used to manage high cholesterol)
- adrenocorticotropic hormone (ACTH) (used to manage ulcerative colitis, crohn’s disease)
- cyclophosphamide or methotrexate (used in cancer management)
- salbutamol or formoterol (used to manage asthma)
- carbenoxolone (used to manage stomach ulcers)
- insulin, chlorpropamide or glibenclamide (medicine used to manage diabetes)
- atropine (used to manage symptoms of low heart rate)
- amantadine (used to manage parkinson’s disease or viral infections)
- allopurinol (used to manage gout)
- calcium salts or vitamin D (used for vitamin deficiency)
B. Drug-Food interaction:
Avoid eating or drinking grapefruit juice while taking TRITELSAR HS 80MG TABLET as it may potentiate the blood pressure lowering effect. Consult your doctor before taking TRITELSAR HS 80MG TABLET.
Overdosage:
If you or anyone else accidentally takes too much of TRITELSAR HS 80MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of TRITELSAR HS 80MG TABLET are low blood pressure, fast or slow heartbeat and dizziness.
Synopsis
| Drug | : | Chlorthalidone, Amlodipine, Telmisartan |
| Pharmacological Category | : | Thiazide Diuretics, Calcium Channel Blockers, Angiotensin II receptor antagonist |
| Therapeutic Indication | : | Essential hypertension |
| Dosage Forms | : | Tablet |
More Information
- Keep TRITELSAR HS 80MG TABLET out of reach of children
- Store TRITELSAR HS 80MG TABLET at room temperature
FAQs About TRITELSAR HS 80MG TABLET
Q: What is TRITELSAR HS 80MG TABLET and why is it given?
A: TRITELSAR HS 80MG TABLET is a combination of chlorthalidone, amlodipine and telmisartan. It is used in the management of essential hypertension (blood pressure that is not caused by any other condition) in adults.
Q: Is TRITELSAR HS 80MG TABLET safe to use in pregnant women?
A: TRITELSAR HS 80MG TABLET is not recommended in early pregnancy and must not be taken when more than 3 months pregnant, as it may cause serious harm to the baby if used after 3 months of pregnancy. Consult your doctor for advice before taking TRITELSAR HS 80MG TABLET.
Q: Can TRITELSAR HS 80MG TABLET be used in patients with liver disease?
A: TRITELSAR HS 80MG TABLET is not recommended for use in patients with severe liver problems such as cholestasis or biliary obstruction (flow of bile from liver stops or slows). It should be used with caution in patients having liver disease. Consult your doctor for advice before taking TRITELSAR HS 80MG TABLET.
Q: Can TRITELSAR HS 80MG TABLET be used in elderly patients?
A: TRITELSAR HS 80MG TABLET should be used with caution in elderly patients (above 65 years of age). Your doctor may adjust the dose with the lowest effective dose depending upon vital organ functions such as kidney, liver and heart. Consult your doctor before taking TRITELSAR HS 80MG TABLET.
Q: Is TRITELSAR HS 80MG TABLET safe to use in patients with kidney problems?
A: TRITELSAR HS 80MG TABLET is not recommended for use in patients with kidney stones and it should be used with caution in patients having kidney artery stenosis (narrowing of blood vessels to one or both the kidneys) and with surgical history of kidney transplant. Consult your doctor before taking TRITELSAR HS 80MG TABLET.
Q: What to do If I forget to take a dose of TRITELSAR HS 80MG TABLET?
A: You should take TRITELSAR HS 80MG TABLET immediately when you remember. If it is time for your next dose skip the missed dose and follow your regular dose schedule. Do not double the dose of TRITELSAR HS 80MG TABLET to match up your missed dose.
References
1. KD. Tripathi. Calcium channel blockers, Diuretics, Drugs Affecting Renin Angiotensin System. Essentials of medical pharmacology. Eighth edition. 2019. Page – 595-597, 630-632, 535-538.
2. A Prem Kumar, Anirudra Ghorai, Vasudev Kriplani, Rabindra Kumar Dash, J Aravinda, Paramesh Shamanna, TK Sabeer, Abdul Hannan and Santosh Revankar. Clinical data analysis of telmisartan for hypertension management in Indian population. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. June 2021. [Accessed on 20th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819792/
3. Connor C. Kerndt; Jayesh B. Patel. Chlorthalidone. National Library of Medicine, National center for biotechnology information. [Revised in May 2022]. [Accessed on 20th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK553174/#:~:text=Mechanism%20of%20Action,Chlorthalidone%20exerts%20its&text=Chlorthalidone%20inhibits%20sodium%20reabsorption%20at,retains%20a%20higher%20sodium%20content.
4. GKM New Pharma. Tritelsar (Chlorthalidone, Amlodipine and Telmisartan Tablets) [Revised in May 2020]. [Accessed on 20th June 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2949.pdf
Useful Diagnostic Tests
- Serum electrolyte panel
- Liver function test
- Kidney function test
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