TRETIN 0.025 Cream 20gm

INTRODUCTION

TRETIN 0.025 CREAM contains Tretinoin, which belongs to the group of medicines called Retinoids. It is used to treat acne. It can also be used to treat wrinkles, skin spots and rough skin. Acne is defined as a skin disease involving inflammation of the sebaceous follicles of the face and upper body, characterized by lesions on the face, back, upper chest and shoulders.

Before using TRETIN 0.025 CREAM, inform your doctor if you have any sunburn, sun sensitivity or any other skin problems. TRETIN 0.025 CREAM should be used in pregnancy only if specifically directed by your doctor. TRETIN 0.025 CREAM should be used with caution in breastfeeding women.

The safety and effectiveness of TRETIN 0.025 CREAM in children (aged less than 12 years) have not been established, so consult your doctor before using it. The most common side effect of using TRETIN 0.025 CREAM is skin irritation like redness, burning, stinging, dryness and peeling. Contact your doctor if any of the side effects worsen.

USES OF TRETIN 0.025 CREAM

• It is used to treat acne, wrinkles, skin spots and rough skin.

HOW TRETIN 0.025 CREAM WORKS

TRETIN 0.025 CREAM works by modifying the abnormal cavity formation that comes from the excessive conversion of cytoplasm to keratin (a strong protein that is the main substance that forms hair, skin, etc.) of epithelial cells, promoting detachment of tough cells and enhancing shedding.

DIRECTIONS FOR USE

Apply TRETIN 0.025 CREAM as advised by your physician. It is for external use only. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

SIDE EFFECTS OF TRETIN 0.025 CREAM

WARNING & PRECAUTIONS

PREGNANCY

TRETIN 0.025 CREAM should be used in pregnant women only if specifically directed by your doctor. Consult your doctor before using it.

BREASTFEEDING

TRETIN 0.025 CREAM should be used with caution in breastfeeding women. Consult your doctor before using it.

ALLERGY

Do not use TRETIN 0.025 CREAM if you are allergic to Tretinoin or any of the other ingredients of this medicine.

INTERACTIONS

A. Drug-Drug interactions:

Before using TRETIN 0.025 CREAM, inform your doctor if you are taking any of the following medicines:

• other medicines used to treat acne (Ex. benzoyl peroxide, resorcinol, salicylic acid)
• medicated or abrasive soaps and cleansers
• medicines containing high concentrations of alcohol, astringents or spices

B. Drug-Food interactions:

Avoid contact of the skin with the lime peel during treatment with TRETIN 0.025 CREAM.

Overdosage:

If you or anyone else accidentally applied too much of TRETIN 0.025 CREAM, contact your doctor immediately. Symptoms of overdose include irritation or increased irritation of your skin.

SYNOPSIS

MORE INFORMATION

• Keep TRETIN 0.025 CREAM out of reach of children
• Store below 25°C

FAQs ABOUT TRETIN 0.025 CREAM

What if I accidentally swallow TRETIN 0.025 CREAM?

TRETIN 0.025 CREAM may be harmful if swallowed. If you accidentally swallow it, call your doctor or poison control centre right away.

What precautions should I take while using TRETIN 0.025 CREAM?

Do not use TRETIN 0.025 CREAM on sunburned skin, cuts, scrapes, eczema or damaged skin. Practice good skin care and avoid exposure to sunlight as you may get sunburned more easily. Use sunscreen and wear clothing and eyewear to protect your skin from the sun. Some weather conditions may irritate your skin. Talk with your doctor in such a case.

Can I use makeup during treatment with TRETIN 0.025 CREAM?

You may use make-up during treatment with TRETIN 0.025 CREAM unless your doctor has told you otherwise. Before using TRETIN 0.025 CREAM, clean the area of treatment where you have applied makeup.

What if I forget to use a dose of TRETIN 0.025 CREAM?

If you forget to use a dose of TRETIN 0.025 CREAM, apply it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not apply TRETIN 0.025 CREAM twice to make up for a forgotten dose.

Can I use other skin preparations with TRETIN 0.025 CREAM?

Do not use any other skin preparations with TRETIN 0.025 CREAM without asking your doctor. Avoid preparations that may dry or irritate your skin, like those containing astringents, alcohol, spices or lime or certain medicated soaps, shampoos, etc. Do not allow anyone else to use this medication. Do not use other medicines containing retinoids which are not recommended by your doctor, as it might cause unnecessary redness or peeling.

REFERENCES

1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Acne Vulgaris. Pharmacotherapy Handbook. Ninth edition. Page- 135.

2. Athina L. Yoham; Damian Casadesus. Tretinoin. StatPearls [Internet]. StatPearls Publishing. March 2022. [Accessed on 24th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK557478/#:~:text=Mechanism%20of%20Action,-The%20exact%20mechanism&text=Tretinoin's%20effectiveness%20as%20an%20acne,cell%20detachment%20and%20enhances%20shedding

3. Ortho-McNeil Pharmaceutical, Inc. U.S. Food & Drug Administration. [Revised in June 2022] [Accessed on 24th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/16921s21s22s25lbl.pdf

4. DPT Laboratories. U.S. Food & Drug Administration. [Revised in January 2012] [Accessed on 24th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/202567Orig1s000lbl.pdf

5. Memorial Sloan Kettering Cancer Center. Tretinoin. [Revised in June 2022] [Accessed on 24th June 2022] https://www.mskcc.org/pdf/cancer-care/patient-education/tretinoin-topical-01

AUTHOR DETAILS

Written By Dr. Dhivakaran R, BDS
Last updated on 16 Nov 2022 | 01:39 PM(IST)