INTRODUCTION

TIOVA SYNCHROBREATHE INHALER contains Tiotropium bromide which belongs to the group of medicines called Bronchodilators. It is used in maintenance treatment of chronic obstructive pulmonary disease (COPD) and help patients breathe more easily.

Chronic obstructive pulmonary disease (COPD) is a breathing disorder in which there is progressive airflow limitation that cannot be fully reversed, characterized by long-term cough and phlegm production. Prior to the treatment, your doctor may want you to take several tests to understand your existing condition.

Before using TIOVA SYNCHROBREATHE INHALER, inform your doctor if you have kidney problem or have suffered from heart attack during the last 6 months, any unstable or life-threatening irregular heart beat, severe heart failure within the past year or urinary retention (difficulty passing urine, painful urination especially in patients with prostate problems).

Also inform your doctor if you have narrow-angle glaucoma, sudden attack of breathlessness or wheezing, intolerance to certain sugar or milk protein. TIOVA SYNCHROBREATHE INHALER should be used in pregnant or breastfeeding women only if specifically directed by your doctor.

TIOVA SYNCHROBREATHE INHALER is not recommended for use in children and adolescents under 18 years, so consult your doctor before using it. The most common side effect of using TIOVA SYNCHROBREATHE INHALER is dry mouth. Contact your doctor if any of the side effects worsen.

USES OF TIOVA SYNCHROBREATHE INHALER

• For maintenance treatment of chronic obstructive pulmonary disease (COPD) 

HOW TIOVA SYNCHROBREATHE INHALER WORKS

TIOVA SYNCHROBREATHE INHALER works by opening your airways and makes it easier for air to get in and out of your lungs. Hence it helps to minimise the effects of the disease in everyday life and to be active longer.

DIRECTIONS FOR USE

Use TIOVA SYNCHROBREATHE INHALER as advised by your physician. It is for inhalation use only. Do not swallow the medicine. Do not to let the medicine enter your eyes as there can be blurred vision, eye pain and/or red eyes, you should wash your eyes in warm water immediately.

Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop using TIOVA SYNCHROBREATHE INHALER unless your doctor advises you to stop.

SIDE EFFECTS OF TIOVA SYNCHROBREATHE INHALER

HOW TO MANAGE SIDE EFFECTS

Dry mouth:

Sipping water frequently or any other sugar free fluids or chewing sugar free gum helps in keeping mouth moist. If symptoms do not improve inform your doctor.

WARNING & PRECAUTIONS

PREGNANCY

TIOVA SYNCHROBREATHE INHALER is not recommended for use in pregnant women or women planning or have a baby unless specifically recommended by your doctor. Consult your doctor before using it.

BREASTFEEDING

TIOVA SYNCHROBREATHE INHALER is not recommended for use in breastfeeding women unless specifically recommended by your doctor. Consult your doctor before using it.

DRIVING AND USING MACHINES

Do not drive or use any machines if you experience dizziness, blurred eyesight or headache after using TIOVA SYNCHROBREATHE INHALER.

KIDNEY

TIOVA SYNCHROBREATHE INHALER should be used with caution patients having trouble/pain while passing urine or other kidney problems. Consult your doctor before using it.

LIVER

Safety and effectiveness of TIOVA SYNCHROBREATHE INHALER in patients with liver problems has not been studied yet.

ALLERGY

Do not use TIOVA SYNCHROBREATHE INHALER if you are allergic to Tiotropium or any of the other ingredients of this medicine.

LUNGS

TIOVA SYNCHROBREATHE INHALER is not recommended for use in patients who have sudden attack of breathlessness or wheezing. Consult your doctor before using it.

HEART DISEASE

TIOVA SYNCHROBREATHE INHALER should be used with caution in patients who had a myocardial infarction (heart attack) in past 6 months or any unstable or life-threatening irregular heartbeat or severe heart failure during the past year. Consult your doctor before using it.

INTERACTIONS

A. Drug - Drug interactions:

Before using TIOVA SYNCHROBREATHE INHALER, inform your doctor if you are taking any of the following medicine:

• other medicines used to widen your airways (Ex. oxitropium, ipratropium)

Overdosage:

If you or anyone else accidentally use too much of TIOVA SYNCHROBREATHE INHALER, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are dry mouth, constipation, trouble passing urine, increased heartbeat or blurred eyesight.

SYNOPSIS

MORE INFORMATION

• Keep TIOVA SYNCHROBREATHE INHALER out of reach of children
• Do not store above 25°C

FAQs ABOUT TIOVA SYNCHROBREATHE INHALER

Q: Can I use TIOVA SYNCHROBREATHE INHALER for sudden breathing problems?

A: TIOVA SYNCHROBREATHE INHALER is not a rescue medicine and is indicated for maintenance treatment of your chronic obstructive pulmonary disease, so it should not be used to treat a sudden breathing problems like breathlessness or wheezing attack. Your doctor may give you suitable alternative to use for sudden breathing problems.

Q: What if TIOVA SYNCHROBREATHE INHALER accidentally gets in my eye?

A: Do not let the contents of TIOVA SYNCHROBREATHE INHALER get into your eyes. This may result in worsening of narrow-angle glaucoma (an eye disease), leading to eye pain or discomfort, blurred eyesight, seeing halos around lights or coloured images related to red eyes. Eye symptoms may occur along with headache, nausea or vomiting. Stop using TIOVA SYNCHROBREATHE INHALER in such case and call your doctor.

Q: Can I stop using TIOVA SYNCHROBREATHE INHALER if symptoms improve?

A: Do not stop using TIOVA SYNCHROBREATHE INHALER without consulting your doctor. The signs and symptoms might worsen if you do so. If you have any more doubts regarding the use of this medicine, ask your doctor.

Q: How does TIOVA SYNCHROBREATHE INHALER work?

TIOVA SYNCHROBREATHE INHALER works by opening your airways and makes it easier for air to get in and out of your lungs. Hence it helps to minimise the effects of the disease in everyday life and to be active longer.

Q: Can TIOVA SYNCHROBREATHE INHALER be used on infants?

A: No. TIOVA SYNCHROBREATHE INHALER is used for adults and not recommended for children and adolescents below 18 years of age. Your doctor will decide the correct dose or select a suitable alternative therapy for your child.

REFERENCES

1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Chronic Obstructive Pulmonary Disease. Pharmacotherapy Handbook. Ninth edition. 2015. Page-835.

2. Keating, G. M. Tiotropium bromide inhalation powder. Drugs. A Review of its Use in the Management of Chronic Obstructive Pulmonary Disease. Springer Link. December 2012. [Accessed on 27th June 2022]. https://link.springer.com/article/10.2165/11208620-000000000-00000

3. Alcibey Alvarado-Gonzaleza and Isabel Arce. Tiotropium Bromide in Chronic Obstructive Pulmonary Disease and Bronchial Asthma. NIH National library of medicine, National centre for biotechnology information. Pubmed 2015. [Accessed on 27th June 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596263/#:~:text=Tiotropium%20bromide%20is%20an%20inhaled,%2Dh%20bronchodilatation%20%5B10%5D.

4. Boehringer Ingelheim Pharma GmbH & Co. KG. Electronic Medicines Compendium (EMC). [Revised in July 2021] [Accessed on 27th June 2022]. https://www.medicines.org.uk/emc/files/pil.1693.pdf

5. Cipla Ltd. Tiotropium bromide. [Revised in January 2022] [Accessed on 27th June 2022]. https://www.ciplamed.com/content/tiova-inhaler

USEFUL DIAGNOSTIC TESTS

• FeNO test
• Spirometry
• Peak flow test
• Chest X-Ray

AUTHOR DETAILS

Written By Dr. Shruthi M R, BDS
Last updated on 18 Jan 2023 | 10:25 AM(IST)