SYMBAL 40mg Tablet 10's

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Duloxetine 40mg
By Torrent Pharmaceuticals Ltd
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(per unit)
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Drug Information for SYMBAL 40mg Tablet 10's

What is SYMBAL?

  • SYMBAL contains duloxetine which belongs to a group of medicines called Serotonin and Noradrenaline Reuptake Inhibitors (SNRIs)
  • It increases the levels of serotonin and noradrenaline in the nervous system







What SYMBAL is used for?

SYMBAL is used in adults to treat:

  • depression
  • generalized anxiety disorder (chronic feeling of anxiety or nervousness)
  • diabetic neuropathic pain (often described as burning, stabbing, stinging, shooting or aching or like an electric shock, there may be loss of feeling in the affected area, or sensations such as touch, heat, cold or pressure may cause pain)
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Talk to your doctor before taking this medicine, if you:

  • are allergic to duloxetine or any of the other ingredients of this medicine
  • have liver disease, severe kidney disease
  • have high blood pressure or heart disease
  • have had seizures (fits)
  • have had mania
  • suffer from bipolar disorder
  • have eye problems, such as certain kinds of glaucoma (increased pressure in the eye)
  • have a history of bleeding disorders (tendency to develop bruises)
  • are at risk of low sodium levels 
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  • If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine
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  • SYMBAL should normally not be used for children and adolescents under 18 years
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  • SYMBAL may make you feel sleepy or dizzy. Do not drive or use any tools or machines until you know how SYMBAL affects you
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Tell your doctor if you are taking,

  • other medicines containing duloxetine
  • another antidepressant medicine called a monoamine oxidase inhibitor (MAOI). Examples of MAOIs include moclobemide (an antidepressant) and linezolid (an antibiotic)
  • fluvoxamine, used to treat depression
  • ciprofloxacin or enoxacin which are used to treat some infections
  • benzodiazepines, strong painkillers, antipsychotics, phenobarbital and antihistamines
  • triptans, tramadol, tryptophan, SSRIs (such as paroxetine and fluoxetine), SNRIs (such as venlafaxine), tricyclic antidepressants (such as clomipramine, amitriptyline), pethidine
  • herbal medicine such as St John’s Wort (Hypericum perforatum) and MAOIs (such as moclobemide and linezolid)
  • medicines with oral anticoagulants or antiplatelet agents
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  • Always take this medicine exactly as your doctor has told you
  • SYMBAL is for oral use
  • You should swallow your medicine whole with a drink of water
  • Take SYMBAL, you may find it easier to take it at the same times every day

For depression and diabetic neuropathic pain:

  • The usual dose of SYMBAL is 60 mg once a day, but your doctor will prescribe the dose that is right for you

For generalized anxiety disorder:

  • The usual starting dose of SYMBAL is 30 mg once a day after which most patients will receive 60 mg once a day, but your doctor will prescribe the dose that is right for you. The dose may be adjusted up to 120 mg a day based on your response to SYMBAL
  • To help you remember to take SYMBAL, you may find it easier to take it at the same times every day

If you take more SYMBAL

  • Call your doctor immediately if you take more than the amount of SYMBAL prescribed by your doctor
  • Symptoms of overdose include sleepiness, coma, serotonin syndrome (a rare reaction which may cause feelings of great happiness, drowsiness, clumsiness, restlessness, feeling of being drunk, fever, sweating or rigid muscles), fits, vomiting and fast heart rate

If you forget to take SYMBAL

  • If you miss a dose, take it as soon as you remember. Do not take a double dose to make up for a forgotten dose. Do not take more than the daily amount of SYMBAL that has been prescribed for you in one day

If you stop taking SYMBAL

  • Do not stop taking your medicine without the advice of your doctor even if you feel better
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Like all medicines, this medicine can cause side effects, although not everybody gets them.





  • lack of appetite
  • trouble sleeping, feeling agitated, less sex drive, anxiety, difficulty or failure to experience orgasm, unusual dreams dizziness, feeling sluggish, tremor, numbness, including pricking or tingling of the skin
  • blurred eyesight
  • tinnitus (hearing sound in the ear when there is no external sound)
  • feeling the heart pumping in the chest
  • increased blood pressure, flushing
  • increased yawning
  • constipation, stomach pain, being sick (vomiting), heartburn or indigestion, breaking wind
  • increased sweating, (itchy) rash
  • muscle pain, muscle spasm
  • painful urination, frequent urination
  • problems getting an erection, changes in ejaculation
  • falls (mostly in elderly people), fatigue
  • weight loss
  • headache, feeling sleepy
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  • throat inflammation that causes a hoarse voice
  • suicidal thoughts, grinding or clenching the teeth, feeling disorientated, lack of motivation
  • sudden involuntary jerks or twitches of the muscles
  • large pupils, problems with eyesight
  • fast and/or irregular heart beat
  • throat tightness, nose bleeds
  • vomiting blood, or black tarry stools (faeces), gastroenteritis, burping, difficulty swallowing
  • inflammation of the liver that may cause abdominal pain and yellowing of the skin or whites of the eyes (jaundice)
  • night sweats, hives, cold sweats, sensitivity to sunlight, increased tendency to bruise
  • muscle tightness, muscle twitching
  • difficulty or inability to pass urine
  • abnormal vaginal bleeding, abnormal periods, including heavy, painful, irregular or prolonged periods, unusually light or missed periods, pain in the testicles or scrotum
  • chest pain, feeling cold, thirst, shivering, feeling hot, abnormal gait
  • weight gain
  • increases in liver enzymes or blood levels of potassium, creatine phosphokinase, sugar, or cholesterol
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  • serious allergic reaction which causes difficulty in breathing or dizziness with swollen tongue or lips or face or throat
  • decreased thyroid gland activity which can cause tiredness or weight gain
  • dehydration, low levels of sodium in the blood
  • “serotonin syndrome” (a rare reaction which may cause feelings of great happiness, drowsiness, clumsiness, restlessness, feeling of being drunk, fever, sweating or rigid muscles), fits increased pressure in the eye (glaucoma)
  • inflammation of the mouth, passing bright red blood in your stools, bad breath, inflammation of the large intestine (leading to diarrhoea)
  • Stevens-Johnson syndrome (serious illness with blistering of the skin, mouth, eyes and genitals)
  • contraction of the jaw muscle
  • abnormal urine odour
  • menopausal symptoms, abnormal production of breast milk in men or women
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  • inflammation of the blood vessels in the skin (cutaneous vasculitis)
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  • Keep this medicine out of reach of children
  • Do not use this medicine after the expiry date
  • Store at room temperature (15-25°C)
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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