SULPITAC 50mg Tablet 10's

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Drug Information

What is Amisulpride used for?

Amisulpride, is used for the long-term treatment of acute and chronic symptoms of mental disorder known as schizophrenia.

Symptoms include

  • delusions (having strange or unusual thoughts);
  • hallucinations (seeing or hearing things that are not there);
  • being suspicious or aggressive for no apparent reason (these are called "positive symptoms");
  • becoming withdrawn and subdued (these are called "negative symptoms").

Amisulpride may also be prescribed for other conditions as determined by your doctor.

How does Amisulpride work?

Amisulpride is an antimigraine agent which belongs to a class of medicines known as selective serotonin reuptake inhibitors agonist. Amisulpride reduces the inflammatory response by binding to serotonin receptors in the brain blood vessel, which causes narrowing of the blood vessels.

How to take Amisulpride?

  • The dosage of oral tablet of Amisulpride depends on the age, weight and medical condition of an individual. Take Amisulpride as prescribed by your doctor.
  • Amisulpride should be taken with or without food. Do not chew the tablet.
  • Swallow the tablet with a glass of water.
  • Amisulpride is not advised to be taken by children less than 18 years of age.
  • Do not discontinue Amisulpride without consulting a doctor.
  • If you miss a dose of Amisulpride, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.
  • You must avoid breastfeeding for 24 hours after taking Amisulpride.

What should you do when you have taken an overdose of Amisulpride?

If you have taken an overdose of Amisulpride, please contact your doctor immediately.

Symptoms of overdose may include the following

  • Restlessness
  • Rigidity of muscles
  • Low blood pressure (hypotension)
  • Drowsiness
  • Sleepiness (somnolence)
  • Loss of consciousness

What are the drugs that interact with Amisulpride?

Drugs that interact with Amisulpride:

  • Amphotericin
  • Anaesthetics
  • Astemizole, Terfinadine
  • Barbiturates
  • Benzodiazepines
  • Bepridil
  • Bromocriptine, Ropinirole
  • Cisapride
  • Clotrimazole
  • Erythromycin, Sparfloxacin
  • Glucocorticoids
  • Halofantrine
  • Haloperidol
  • Imipramine, Lithium
  • Levodopa,
  • Methadone
  • Morphine, Pethidine
  • Nebivolol, Bisoprolol, Diltiazem, Verapamil, Clonidine, Guanfacine, Digoxin
  • Pentamidine
  • Pimozide
  • Promethazine
  • Quinidine, Disopyramide, Procainamide, Amiodarone, Sotalol
  • Sultopride, Thioridazine
  • Tetracosactide
  • Tramadol, Indomethacin
  • Vincamine

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Amisulpride?

Most common side effects of Amisulpride are:

  • Hypotension
  • Constipation, nausea, vomiting, dry mouth, weight gain
  • Galactorrhoea (increased milk secretion from breast)
  • Amenorrhoea or menstrual disorders
  • Gynaecomastia,
  • Breast pain or enlargement
  • Erectile dysfunction
  • Insomnia
  • Anxiety, agitation
  • Orgasmic dysfunction (inability to achieve orgasm)
  • Tremor, rigidity
  • Hypokinesia (partial or complete loss of muscle movement)
  • Hypersalivation
  • Akathisia (inability to sit still)
  • Dyskinesia (impairment of voluntary movement)
  • Acute dystonia (sustained muscle contractions)

Please stop your tablets and contact your physician immediately if you have

  • allergic reaction (itchiness, rash, swallowing and breathing difficulty, swelling of face, mouth tongue and lips);
  • seizure;
  • neuroleptic malignant syndrome (high temperature, sweating, stiffness of muscles, increased heartbeat, fast breathing and confusion, drowsiness, agitation);
  • chest pain, increased heart rate, irregular heartbeat, shortness of breath, wheezing, tightness in your chest, pain or pressure in jaw, neck or chest, (symptoms resembling a heart attack);
  • blood clots in veins (swelling, pain and redness in legs);
  • fever, sore throat, mouth ulcers;
  • syndrome of inappropriate antidiuretic hormone secretion (SIADH) (felling unwell, confusion, weakness, nausea, loss of appetite, irritability);
  • withdrawal symptoms after stopping Amisulpride (nausea, difficulty sleeping, restlessness, muscle stiffness, abnormal movements, original illness may come back).

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Amisulpride?

Seek doctor’s advice before taking any other drug or herbal products while on Amisulpride.

You are advised not to take Amisulpride if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Amisulpride?

Tell your doctor if

  • you are allergic to Amisulpride or other medicine from the same class.
  • you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • you have Parkinson’s disease.
  • you have had epileptic seizures.
  • you have an unusual heart rate.
  • you have had a heart attack, chest pain on resting, high blood pressure, uncontrolled high blood pressure.
  • you are at risk of heart disease.
  • you have long QT syndrome.
  • you have liver or kidney disease.
  • you are over 65 years of age.
  • you are taking antidepressants.
  • you have had a stroke.
  • you have low amount of potassium and magnesium in your blood.
  • you have obstruction of large arteries of arms and legs (peripheral vascular disease)
  • you are taking other medicines for migraine.
  • you are planning a surgery or any procedure.
  • you are pregnant or trying to conceive or are breastfeeding.

Frequently asked questions about Amisulpride

  • How should Amisulpride be stored?
  • Amisulpride tablets does not require any special storage conditions. Amisulpride must be kept out of children’s reach.

  • Should I follow any special dietary instructions while taking Amisulpride?
  • No, you can have your normal diet unless advised by your doctor.

  • Can I drive while taking Amisulpride?
  • Amisulpride causes drowsiness and sleepiness in some individuals. It is advisable not to drive while taking Amisulpride.

  • Can I drink alcohol with Amisulpride?
  • No, you are not advised to drink alcohol while taking Amisulpride, as the medicine can increase the effect of alcohol.


    The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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