INTRODUCTION

SIRDALUD 2MG TABLET contains Tizanidine which belongs to a group of medicines called Skeletal muscle relaxants. It is used to relieve the stiffness and restriction of muscles resulting from multiple sclerosis, injury or diseases of the spinal cord.

Multiple sclerosis is a disease in which the immune system destroys the protective layer of nerves resulting in cramping, difficulty in walking, muscle paralysis, etc. Your doctor may want you to take several blood tests and liver function tests to understand your existing condition. Do not consume alcohol while taking this medicine.

SIRDALUD 2MG TABLET is not recommended for use in patients with severe liver problems, or rare hereditary problems of galactose intolerance, lapp lactase deficiency, or glucose galactose malabsorption. Before using SIRDALUD 2MG TABLET consult your doctor if you have any kidney, liver, heart disease (like coronary artery disease), or intolerance to any sugars.

SIRDALUD 2MG TABLET is not recommended in pregnant and breastfeeding women. It is not recommended for use in children and adolescents below 18 years of age. SIRDALUD 2MG TABLET should be used with caution in geriatric patients. The most common side effects of using this medicine are drowsiness, tiredness, dizziness, dry mouth. Consult your doctor if these side effects get more severe.

USES OF SIRDALUD 2MG TABLET

• It is used to relieve the stiffness and restriction of muscles resulting from multiple sclerosis, injury or diseases of the spinal cord

HOW SIRDALUD 2MG TABLET WORKS

SIRDALUD 2MG TABLET works on the specific centres in the brain and spinal cord to relieve muscle spasm and stiffness without reduction in strength. Thus relieves the pain and improves muscle movement.

DIRECTIONS FOR USE

Take SIRDALUD 2MG TABLET as advised by your physician. Swallow SIRDALUD 2MG TABLET with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF SIRDALUD 2MG TABLET

HOW TO MANAGE SIDE EFFECTS

Stomach upset:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Consult your doctor immediately if you feel sick.

Nausea:

Stick to simple meals. Avoid eating oil-rich or spicy foods. Keep yourself hydrated. Consult your doctor immediately if symptoms do not improve.

Tiredness, Dizziness:

Try to rest and relax. Apply a relaxing balm to ease off the pain or discomfort. Do not use any machinery or drive until you feel better. If there is no improvement in the symptom, contact your doctor at the earliest.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interactions:

Before taking SIRDALUD 2MG TABLET, inform your doctor, if you are taking any of the following medicine:

• medicines to treat depression (Ex. fluvoxamine)
• some antibiotics known as fluoroquinolones (Ex. enoxacin, pefloxacin or norfloxacin) to treat infections
• medicine to treat an abnormal heart rhythm (Ex. amiodarone, mexiletine or propafenone)
• medicines to treat indigestion and digestive ulcers (Ex. cimetidine)
• pain killers (Ex. rofecoxib)
• contraceptive pills (Ex. progestin/oestrogen)
• medicine to prevent blood clots (Ex. ticlopidine)
• any medicine to treat high blood pressure (Ex. atenolol, propranolol, furosemide)
• medicine to treat congestive heart failure (Ex. digoxin)
• medicines for sleeping problems or anxiety (Ex. temazepam)

Overdosage:

If you or anyone else accidentally takes too much of SIRDALUD 2MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms include nausea, vomiting, low blood pressure, a slow or abnormal heartbeat, dizziness, small pupils, difficulty breathing, coma, restlessness, or sleepiness.

SYNOPSIS

MORE INFORMATION

• Keep this medicine out of reach in children
• Store SIRDALUD 2MG TABLET at room temperature

FAQs ABOUT SIRDALUD 2MG TABLET

What is SIRDALUD 2MG TABLET used for?

SIRDALUD 2MG TABLET contains Tizanidine which belongs to a group of medicines called skeletal muscle relaxants. It is used to relieve the stiffness and restriction of muscles resulting from multiple sclerosis, injury or diseases of the spinal cord.

How does SIRDALUD 2MG TABLET work?

SIRDALUD 2MG TABLET works on the specific centres in the brain and spinal cord to relieve muscle spasms and stiffness without a reduction in strength. This relieves the pain and improves muscle movement.

Does SIRDALUD 2MG TABLET lower blood pressure?

Yes, SIRDALUD 2MG TABLET can lower blood pressure, so it is not recommended for use with other blood pressure medications. Consult your doctor for advice.

Can SIRDALUD 2MG TABLET be taken with ibuprofen?

No interactions were found with SIRDALUD 2MG TABLET and ibuprofen. However, consult your doctor before taking any medicine along with SIRDALUD 2MG TABLET for safety reasons.

Can SIRDALUD 2MG TABLET be used in pregnant women?

SIRDALUD 2MG TABLET is not recommended for use in pregnant women or women planning to have a baby. If you are pregnant or think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.

REFERENCES

1. K.D Tripathi. Skeletal Muscle Relaxants. Essentials of medical pharmacology. Seventh edition. 2013. Page –347.

2. Shirin Ghanavatian, Armen Derian. Tizanidine. NIH National Library of Medicine, National center for biotechnology information. Statpearls. September 2022 [Accessed on 14th December 2022] https://www.ncbi.nlm.nih.gov/books/NBK519505/

3. D M Coward. Tizanidine: neuropharmacology and mechanism of action. NIH National Library of Medicine, National centre for biotechnology information. Pubmed.gov. November 1994. [Accessed on 14th December 2022] Tizanidine: neuropharmacology and mechanism of action - PubMed (nih.gov)

4. Novartis Pharma. Tizanidine. [Revised in February 2017] [Accessed on 14th December 2022] https://www.hpra.ie/img/uploaded/swedocuments/2188598.PPA0465_168_002.1fdbbd95-34c9-4609-b8da-859c4fe9e9dc.000001Zanaflex%20Combined%20PIL.170214.pdf

5. Acorda Therapeutics Inc. U.S. Food & Drug Administration. Tizanidine. [Revised in October 2013] [Accessed on 14th December 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021447s011_020397s026lbl.pdf

6. Teva Pharmaceuticals works pvt ltd. Tizanidine. [Revised in October 2021] [Accessed on 14th December 2022] https://products.tevauk.com/mediafile/id/51646.pdf

USEFUL DIAGNOSTIC TESTS

• Complete blood tests
• Liver function test