Simbrinza Eye Drops 5ml


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Drug Information for Simbrinza Eye Drops 5ml

What is SIMBRINZA?

  • SIMBRINZA contains Brimonidine and Brinzolamide
  • Brinzolamide belongs to a group of medicines called carbonic anhydrase inhibitors
  • Brimonidine belongs to a group of medicines called alpha adrenergic agonists
CONSUMER MEDICINE INFORMATION

THERAPEUTIC USES

WARNING & PRECAUTIONS

INTERACTIONS

DIRECTIONS FOR USE

SIDE EFFECTS

MORE INFORMATION

What SIMBRINZA is used for?

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TALK TO YOUR DOCTOR

PREGNANCY AND BREAST-FEEDING

CHILDREN AND ADOLESCENTS

DRIVING AND USING MACHINES

Talk to your Doctor before use of this medicine, if you:

  • are allergic (hypersensitive) to Brimonidine and Brinzolamide or any of the other ingredients of this medicine
  • suffer from depression
  • suffer from heart disease or heart problems
  • suffer from dizziness or light-headedness on standing up (due to a fall in blood pressure)
  • suffer from reduced mental capacity, reduced blood supply to the brain
  • suffer from blood vessel disease in the limbs, or from poor blood circulation which makes the fingers or toes numb and pale
  • have dry eyes or cornea problems
  • have been told you have the following eye conditions: pseudo exfoliative, pigmentary or narrow angle glaucoma
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  • SIMBRINZA should not be used while breast-feeding
  • If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine
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  • It is not usually recommended for use in a child between the ages of 2 and 12
  • Talk to your doctor if it is intended for use in this age group
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  • SIMBRINZA may cause blurred or abnormal vision. This effect may seem worse at night or in reduced lighting
  • If you experience any of these symptoms, do not drive or use machinery until the symptoms are cleared
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Tell your doctor if you are using:

  • monoamine oxidase (MAO) inhibitors medicine or any other antidepressants
  • chlorpromazine, methylphenidate or reserpine (for mental/personality disorders)
  • pain killers
  • medicines which work in the same way as brimonidine, prazosin and isoprenaline
  • other sulphonamide medicines
  • sedative, barbiturate, opiates or hypnotic medicines
  • carbonic anhydrase inhibitor (acetazolamide or dorzolamide)
  • medicines for treating a heart condition or for lowering blood pressure
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  • Always use this medicine exactly as your doctor has told you. Check with your doctor if you are not sure
  • The recommended dose is one drop into each affected eye twice daily, approximately 12 hours apart
  • Avoid touching the eye (or any other surface) with the tip of the bottle
  • If you wear soft contact lenses, they should be removed before using the eye drops and wait at least 15 minutes before reinserting
  • Hold the bottle upside down above the eye and gently squeeze the bottle to release a drop into your eye
  • Keep the affected eye closed and press your fingertip against the inside corner of the closed eye, and hold for 1 minute
  • Repeat for the other eye if necessary
  • Replace and tighten the cap immediately after use

If you use more SIMBRINZA

  • If you use too many drops or if the eye drops are accidentally swallowed, you should contact your doctor

If you forget to use SIMBRINZA

  • Apply the drops as soon as you remember. However, if it is almost time for your next dose, do not double your dose and carry on with the normal schedule dose

If you stop using SIMBRINZA

  • To be effective it must be used every day. Do not stop using SIMBRINZA until your doctor tells you so
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Like all medicines, this medicine can cause side effects, although not everybody gets them.

SERIOUS

COMMON

UNCOMMON

RARE

VERY RARE

Brimonidine:

  • allergic reaction (difficulty breathing, closing of the throat, swelling of the lips, tongue, or face or hives) to brimonidine

Brinzolamide:

  • eye pain, redness of the eye, blurred vision, increased tear production with possible sensitivity to light, or a feeling that something is in the eye
  • difficulty breathing, increase in rate of breathing with sweating, wheezing or crackling sounds
  • heavy or pressing sensation on your chest with chest pain
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Brimonidine

  • an allergic reaction in the eye causing eye redness, burning, stinging, follicles or white spots on the membrane covering the inside of the eyelid/white of the eye, blurred vision, a feeling of something in the eye or itching
  • headache, tiredness, drowsiness and dry mouth
  • changes to the surface of the eye, swollen or red eyelid, abnormal vision, sticky, weepy or watery eyes, sensitivity to light, irritation, pain, whitening of the membrane covering the inside of the eyelid/white of the eye inflammation of the see-through layer which covers the surface of the eye
  • cold-like symptoms or abnormal taste

Brinzolamide

  • bitter or unusual taste in your mouth
  • eye irritation

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Brimonidine

  • depression
  • palpitations or changes in heart rate
  • dry nose or general allergic reactions

Brinzolamide:

  • eye sensitivity to light
  • dry or itchy eye
  • eye discharge, inflammation of the eyelid glands
  • growth on surface of eye
  • increased pigmentation of the eye or a grey coloured band around the eye
  • fatty or mineral deposits in or around the eye
  • tired eyes, eyelid crusting
  • increased tear production
  • decreased heart rate, palpitations, which can be felt as a thumping in your chest
  • decreased red blood cell count in the blood
  • blood tests show an increased chloride level in the blood
  • dizziness, depression or lack of enthusiasm or interest
  • tingling or pins and needles sensations in the hands or feet
  • having nightmares, nervousness
  • decreased sex drive or problems getting or maintaining an erection
  • throat irritation, pain or sore throat
  • mucus build up in back of nose or throat
  • abnormal or decreased sensation in mouth
  • inflammation of the lining of the food pipe with pain
  • abdominal pain, nausea, vomiting, upset stomach or indigestion
  • frequent bowel movements, diarrhoea or intestinal gas
  • headache
  • muscle pain or muscle spasms, back pain
  • difficulty walking or lifting
  • nose bleeds, runny nose, or sneezing
  • red rash or an red area of skin with small bumps
  • skin tightness
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Brimonidine

  • shortness of breath

Brinzolamide:

  • difficulty sleeping
  • drowsiness
  • increased pressure in eye
  • damage to the optic nerve
  • abnormal , double or reduced vision
  • seeing flashing lights with discomfort or pain
  • decreased eye sensation
  • puffy eyes or swelling around the eyes
  • irregular heart rate
  • dry or stuffy nose
  • chest congestion or cough
  • itchy rash (known as nettle rash) or hives
  • itching
  • loss of hair
  • generalised weakness
  • feeling jittery or irritable
  • chest pain
  • difficulty with memory
  • ringing in ears
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Brimonidine

  • eye inflammation or a reduction in pupil size
  • fainting, high or low blood pressure or sleeplessness
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STORAGE

  • Keep this medicine out of the sight and reach of children
  • Do not use this medicine after the expiry date
  • Store at room temperature (15-25°C)
  • Discard the medicine after 1 month of opening
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Disclaimer:

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Disclaimer:

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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