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Introduction About SAFEROXIM 500 TABLET
SAFEROXIM 500 TABLET is an antibiotic medicine used in the management of various bacterial infections such as infections of the respiratory tract, throat infections, skin infections, ear infections, sinus infections, lung infections and urinary tract infections. It can also be used in the management of Lyme disease at its early stages.
It contains a medicine called Cefuroxime which is a powerful antibiotic agent that works by killing the susceptible organism that causes infection.
Take SAFEROXIM 500 TABLET as directed by your physician. It can be taken after meals for better absorption. Usually, it is prescribed for 7-10 days to attain better control on infection. Therefore, do not stop taking this medicine or skip doses, as it may make this medicine less effective.
Before taking SAFEROXIM 500 TABLET, inform your doctor if you have kidney problems. You must also inform your doctor if you are allergic to any antibiotics, previously experienced anaemia after taking antibiotics, scheduled for any blood tests, or if you are pregnant or breastfeeding.
The most common side effects of taking this medicine are headache, dizziness, diarrhoea and feeling sick. Consult your doctor immediately if any of the above symptoms worsen.
Uses Of SAFEROXIM 500 TABLET
SAFEROXIM 500 TABLET is used in the management of various bacterial infections such as:
- Respiratory tract infections (such as bronchitis, pneumonia)
- Throat infections
- Sinus infections
- Skin infections
- Ear infections
- Urinary tract infections
- Lyme’s disease
How SAFEROXIM 500 TABLET Works
SAFEROXIM 500 TABLET contains cefuroxime which is a second-generation cephalosporin that interferes with the synthesis of the bacterial cell wall by binding to specific binding proteins located inside the bacterial cell wall. This leads to breaking down the cell wall of the bacteria and reducing its stability, thus causing cell damage, and eventually causing bacterial elimination.
How to use SAFEROXIM 500 TABLET
- Take SAFEROXIM 500 TABLET as advised by your physician. It can be taken after meals for better absorption
- Swallow the medicine with a glass of water. Do not crush or chew the medicine.
- Do not exceed the recommended daily dosages
- Do not stop taking or skip doses of SAFEROXIM 500 TABLET to achieve better control over infection
- Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of infection.
Side Effects Of SAFEROXIM 500 TABLET
Common Side Effects of SAFEROXIM 500 TABLET:
- fungal infection
- headache, dizziness
- diarrhoea
- nausea, stomach pain
- increased type of white blood cells (eosinophilia)
- increase in liver enzyme
- skin rashes
- increased number of blood platelets
- decreased number of white blood cells
- positive coombs test
Stop taking SAFEROXIM 500 TABLET and consult your doctor immediately if you experience any of the following side effects
- fungal infection such as thrush
- severe diarrhoea with blood and mucus, stomach pain and fever
Warning & Precautions
Pregnancy
Consult your doctorThere are no adequate and well-controlled studies regarding the use of cefuroxime in pregnant women. Therefore, SAFEROXIM 500 TABLET should be used in pregnant women only if required. Your doctor will decide whether you should take this medicine or not based on the risk and benefits of the medicine.
Breastfeeding
Monitoring requiredStudies have shown that Cefuroxime may pass through the breast milk. Therefore, SAFEROXIM 500 TABLET should be used in breastfeeding women only under careful medical supervision. Consult your doctor for advice.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy after taking SAFEROXIM 500 TABLET.
Kidney
Use with CautionSAFEROXIM 500 TABLET should be used with caution in patients with history of kidney problems and if needed dosage will be adjusted accordingly. Consult your doctor before taking the medicine.
Allergy
ContraindicatedDo not take SAFEROXIM 500 TABLET if you are allergic (hypersensitive) to Cefuroxime, cephalosporin, penicillin, monobactams, carbapenems or to any other ingredients of this medicine.
Use In Pediatrics
Consult your doctorSAFEROXIM 500 TABLET can be used in children only if prescribed by the physician. Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition.
Use In Geriatrics
Use with CautionSAFEROXIM 500 TABLET should be used with caution in elderly especially patients with renal impairment. Consult your doctor before taking the medicine.
Others
SAFEROXIM 500 TABLET is not recommended for use if you:
- have cephalosporin-associated hemolytic anaemia
Before taking SAFEROXIM 500 TABLET, inform your doctor if you are:
- going to undergo blood sugar test or coombs test
Interactions
A. Drug-Drug interactions:
Before taking SAFEROXIM 500 TABLET, inform your doctor if you are taking any of the following medicine:
- Other antibiotics (Ex: streptomycin, neomycin, gentamycin)
- Antacids (such as calcium carbonate)
- Anticoagulants (Ex. warfarin)
- Birth control pills (Ex. ethinyl estradiol)
- Anti-gout agents (Ex. probenecid)
Overdosage:
If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms are neurological disorders such as seizures (fits).
Synopsis
| Drug | : |
Cefuroxime |
| Pharmacological Category | : |
Cephalosporin Antibiotics |
| Therapeutic Indication | : |
Manages Bacterial infections |
| Dosage Forms | : |
Tablet, Injection, Capsule, Syrup, Dry Suspension, Drops, Dispersible tablet |
More Information
Storage
- Keep out of reach of children
- Store at room temperature
FAQs About SAFEROXIM 500 TABLET
Q: What is SAFEROXIM 500 TABLET used for?
A: SAFEROXIM 500 TABLET is an antibiotic medicine used in the management of various bacterial infections such as infections of the respiratory tract, throat infections, skin infections, ear infections, sinus infections, lung infections and urinary tract infections. It can also be used in the management of Lyme disease at its early stages.
Q: Is SAFEROXIM 500 TABLET same as penicillin?
A: No, SAFEROXIM 500 TABLET (which contains cefuroxime, a type of cephalosporin antibiotic) is not the same as penicillin. Both cefuroxime and penicillin are antibiotics, but they belong to different classes and have different chemical structures. While they work similarly by targeting bacterial cell walls, they are used in the management of slightly different infections, and some people who are allergic to penicillin may also react to cephalosporins like cefuroxime. It’s always best to check with a healthcare provider before taking a new antibiotic, especially if you have a penicillin allergy.
Q: If I start feeling well, can I skip the dose of SAFEROXIM 500 TABLET?
A: No. You should complete the full course of SAFEROXIM 500 TABLET as prescribed by your doctor. It is important that SAFEROXIM 500 TABLET be taken at the right dose and for the right duration given. Otherwise, the symptoms can prevail and sometimes worsen. Consult your doctor before taking the medicine.
Q: Will SAFEROXIM 500 TABLET affect the contraceptive pill that is taken?
A: Yes. SAFEROXIM 500 TABLET may interact with birth control pills and lowers its efficiency. So, you should tell your doctor if you are using any birth control pills. Your doctor could suggest an alternative contraceptive barrier to manage unwanted pregnancies.
Q: In what condition SAFEROXIM 500 TABLET should be avoided?
A: SAFEROXIM 500 TABLET should not be taken if you have a history of serious anaphylactic reaction to cefuroxime or any other cephalosporin antibiotics or if you have a history of cephalosporin-induced haemolytic anaemia. Consult your doctor before taking SAFEROXIM 500 TABLET.
Q: Can SAFEROXIM 500 TABLET be used in children?
A: SAFEROXIM 500 TABLET can be used in children only if prescribed by the physician. Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition.
Q: Can SAFEROXIM 500 TABLET be used during pregnancy?
A: There are no adequate and well-controlled studies regarding the use of cefuroxime in pregnant women. Therefore, SAFEROXIM 500 TABLET should be used in pregnant women only if required. Your doctor will decide whether you should take this medicine or not based on the risk and benefits of the medicine.
References
1. KD Tripathi. Second-generation cephalosporins. Essentials of Medical Pharmacology. Eighth edition. Page - 777.
2. Brogden, R.N., Heel, R.C., Speight, T.M. et al. Cefuroxime: A Review of its Antibacterial Activity, Pharmacological Properties and Therapeutic Use. Drugs. [Revised in November 2012] [Accessed on 7th September 2022] click here
3. Sandoz Limited. Electronic Medicines Compendium (EMC) [Revised in December 2020] [Accessed on 7th September 2022] click here
4. TEVA UK Ltd. Health Products Regulatory Authority. [Revised in June 2013] [Accessed on 7th September 2022] click here
5. Blenheim Pharmacal, Inc. [Revised in June 2010] [Accessed on 7th September 2022] click here
10. GlaxoSmithKline. [Revised in January 2007] [Accessed on 7th September 2022] click here
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