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INTRODUCTION
RUTO WEL D is a combination of Bromelain, Rutoside, Trypsin and Diclofenac which belongs to the group of medicines called Proteases, Flavonoids, Proteolytic enzymes and Analgesics respectively. It is used in the treatment of pain and inflammation associated with rheumatoid arthritis, osteoarthritis, sports injuries, tooth extraction. RUTO WEL D is also used to treat post-surgical inflammation and helps in wound healing and has an anti-scarring effect.
Prior to starting the treatment with RUTO WEL D, your doctor might want you to take up several diagnostic tests to understand the existing condition.
RUTO WEL D is not recommended for use in patients having kidney or liver disorders, high blood pressure, bleeding or clotting disorders, blood in vomiting or urine and infection. It should be taken with caution in patients who have heart disease.
RUTO WEL D is not recommended for use in pregnant and breast-feeding women. There is no data on the use of RUTO WEL D in children and elderly patients hence, caution must be exercised while taking this medicine. Always, consult with your doctor before taking it.
The most common side effects of taking RUTO WEL D are nausea, loss of appetite, headache, diarrhoea and flatulence. Consult with your doctor if any of these worsen or doesn’t improve.
USES OF RUTO WEL D
- Provides relief from pain and inflammation
HOW RUTO WEL D WORKS
RUTO WEL D helps in treating pain and inflammation associated with various conditions where bromelain is a protease enzyme which decreases inflammation by inhibiting the substances that are responsible for it called proinflammatory prostaglandins. It also influences blood clotting by increasing the activity of a protein called fibrinogen. Rutoside is a flavonoid that works by enhancing the strength of blood vessels and decreases their ability to break down. Diclofenac is a non-steroidal anti-inflammatory drug which acts by stopping the release of certain chemicals called prostaglandins which is responsible for the occurrence of pain and inflammation.
DIRECTIONS FOR USE
Take RUTO WEL D as advised by your physician. Swallow the medicine as a whole with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of RUTO WEL D for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF RUTO WEL D
COMMON
- headache, dizziness
- vertigo, sickness
- nausea
- flatulence, diarrhoea
- loss of appetite
- skin rash
RARE
- sleepiness
- skin spots
- oedema (swelling due to fluid build up)
Stop taking RUTO WEL D and consult your doctor immediately if you experience the following side effects:
- mild cramping and tenderness of the abdomen followed by rectal bleeding or bloody diarrhoea
- stomach or duodenal ulcer, bleeding from the stomach or intestine, stomach pain or other abnormal stomach symptoms
- passing blood in your faeces, vomiting blood or dark particles that look like coffee grounds
- indigestion or heartburn
- allergic reactions (signs include sudden wheeziness, difficulty in breathing, swelling of the face, lips, hands or fingers, skin rash, itching, bruising, painful red areas, peeling or blistering)
- chest pain (sign of a potentially serious allergic reaction called Kounis syndrome)
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom does not improve.
Nausea And Vomiting
Try to take RUTO WEL D with or just after a meal or a snack. Stick to simple meals. Avoid eating oil rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.
Headache
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Do not consume too much of alcohol. Consult your doctor if the symptom does not improve.
WARNING & PRECAUTIONS
PREGNANCY
ContraindicatedRUTO WEL D is not recommended for use in pregnant women. Consult your doctor before taking it.
BREASTFEEDING
ContraindicatedRUTO WEL D is not recommended for use in breastfeeding women. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Use with CautionDo not drive or operate any machines if you experience dizziness or sleepiness. Consult your doctor before taking it.
ALCOHOL
ContraindicatedAvoid the use of alcohol with RUTO WEL D as it can increase the risk of gastric irritation.
KIDNEY
ContraindicatedRUTO WEL D is not recommended for use in patients having kidney disorders. Consult your doctor before taking it.
LIVER
ContraindicatedRUTO WEL D is not recommended for use in patients having liver disorders. Consult your doctor before taking it.
ALLERGY
ContraindicatedDo not take RUTO WEL D if you are allergic to Bromelain, Rutoside, Trypsin and Diclofenac.
HEART DISEASE
Use with CautionRUTO WEL D should be used with caution in patients having heart disease. Consult your doctor before taking it.
USE IN GERIATRICS
Consult your doctorYour doctor will decide the correct dose and duration of the treatment with RUTO WEL D depending upon your age, disease condition and body weight. Consult your doctor for advice.
OTHERS
RUTO WEL D is not recommended for use if you:
- have high blood pressure
- have bleeding or clotting disorders
- have blood in vomiting or urine
- have infection
INTERACTIONS
A. Drug – Drug Interactions:
Before taking RUTO WEL D inform to your doctor, if you are taking any of these medicines:
- cardiac glycosides such as digoxin (used to treat heart problems), antihypertensives such as ramipril (used to treat high blood pressure)
- lithium (used to treat bipolar disorder)
Overdosage:
If you or anyone else accidentally take too much of RUTO WEL D, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Bromelain, Rutoside, Trypsin, Diclofenac |
| Pharmacological Category | : | Proteas, Flavonoids, Proteolytic enzymes, Analgesics |
| Therapeutic Indication | : | Pain and Inflammation |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep RUTO WEL D out of reach of children
- Store at room temperature
FAQs ABOUT RUTO WEL D
Q: What is RUTO WEL D and why is it prescribed?
A: RUTO WEL D is a combination of Bromelain, Rutoside, Trypsin and Diclofenac which belongs to the group of medicines called Proteases, Flavonoids, Proteolytic enzymes and Analgesics respectively. It is used in treatment of pain and inflammation associated with rheumatoid arthritis, osteoarthritis, sports injuries, tooth extraction. RUTO WEL D is also used to treat post-surgical inflammation and helps in wound healing and has an anti-scarring effect.
Q: Can RUTO WEL D cause stomach disturbances?
A: Yes, RUTO WEL D may cause side effects like nausea, diarrhoea, indigestion and flatulence. Keep a check on your food habits while taking RUTO WEL D, consume less spicy and healthy food and drink plenty of liquid. Do not take any medication on your own. Ask for your doctor’s advice if these doesn’t improve.
Q: What should I tell my doctor before taking RUTO WEL D?
A: Before taking RUTO WEL D tell your doctor if you have any heart, kidney or liver disorders, high blood pressure, bleeding or clotting disorders, blood in vomiting or urine and infection.
Q: Is RUTO WEL D safe for pregnant and breast-feeding women?
A: RUTO WEL D is not recommended for use in pregnant and breast-feeding women. Consult your doctor for advice to select a suitable alternative medicine to treat pain and inflammation.
Q: Can RUTO WEL D be given to children?
A: There is no information regarding the use of RUTO WEL D in children. Your child’s doctor will select a alternative or decide the correct dose and duration of the treatment with RUTO WEL D depending upon your child’s age, disease condition and body weight.
REFERENCES
1. K.D. Tripathi. Drugs Affecting Blood and Blood Formation, Autacoids and Related Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 616 & 204
2. R.S. Satoskar, Nirmala N. Rege, S.D. Bhandarkar. Enzymes in Therapy. Pharmacology and Pharmacotherapeutics. Twenty Fourth Edition. 2015. Page – 1670, 1103
3. Pavan R, Jain S, Shraddha, Kumar A. Properties and therapeutic application of bromelain: a review. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. December 2012. [Accessed on 4th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529416/
4. Diclofenac Sodium. NIH National Library of Medicine, National center for biotechnology information. [Accessed on 4th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK557879/
5. Shah D, Mital K. The Role of Trypsin: Chymotrypsin in Tissue Repair. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. January 2018. [Accessed on 4th July 2022] https://pubmed.ncbi.nlm.nih.gov/29209994/
6. Swiss Caps GmbH. Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed on 4th July 2022] https://www.medicines.org.uk/emc/files/pil.1118.pdf
7. Tasmed India Pvt Ltd. Rutor D. [Accessed on 4th July 2022] https://tasmedlab.com/allproduct/rutor-rutor-d/
8. Leo Genic Healthcare. LoeTryps D. [Accessed on 4th July 2022] https://www.leogenic.com/leotryps-d-trypsin-bromelain-rutoside-diclofenac-tablets/
USEFUL DIAGNOSTIC TESTS
- Complete blood count
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